CSNK1A1 and Gli2 as novel targets identified through an integrative analysis of gene expression data, protein-protein interaction and pathways networks in glioblastoma tumors: Can these two be antagonistic proteins?

Cancer Informatics

Volumn 13, Issue , 2014, Pages 93-108

  Mishra, Seema ^a  

^a UNIVERSITY OF HYDERABAD   (India)

Author keywords

Alpha 1 (CSNK1A1) and glioma associated oncogene 2 (Gli2) proteins; Bottleneck nodes; Casein kinase 1; Gene expression; Glioblastoma; Integrative analysis; Protein protein interaction networks; Simultaneous targeting; Wnt and SHH signaling pathways; catenin (CTNNB1)

Indexed keywords

APC PROTEIN; BETA CATENIN; CASEIN KINASE; CASEIN KINASE 1 ALPHA 1; FAS ANTIGEN; FRIZZLED PROTEIN; GLIOMA ASSOCIATED ONCOGENE 2 PROTEIN; GLYCOGEN SYNTHASE KINASE 3BETA; LOW DENSITY LIPOPROTEIN RECEPTOR RELATED PROTEIN 5; LOW DENSITY LIPOPROTEIN RECEPTOR RELATED PROTEIN 6; LYMPHOID ENHANCER FACTOR 1; MESSENGER RNA; PROTEIN PATCHED 1; PROTEIN PATCHED 2; SECRETED FRIZZLED RELATED PROTEIN 1; SMOOTHENED PROTEIN; SONIC HEDGEHOG PROTEIN; TRANSCRIPTION FACTOR 7 LIKE 1; TRANSCRIPTION FACTOR GLI1; TRANSCRIPTION FACTOR GLI2; TRANSCRIPTION FACTOR GLI3; TUMOR MARKER; UNCLASSIFIED DRUG; WNT PROTEIN; WNT5A PROTEIN;

APC GENE; ARTICLE; CONTROLLED STUDY; CSNK1A1 GENE; DOWN REGULATION; FAS GENE; FRIZZLED RECEPTOR GENE; GENE; GENE EXPRESSION; GENE IDENTIFICATION; GLI1 GENE; GLI2 GENE; GLI3 GENE; GLIOBLASTOMA; GSK3 BETA GENE; HUMAN; HUMAN TISSUE; INTRACELLULAR SIGNALING; JAG2 GENE; LEF1 GENE; LRP5 GENE; LRP6 GENE; MAJOR CLINICAL STUDY; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; PROTEIN TARGETING; PTCH1 GENE; PTCH2 GENE; SFRP1 GENE; SHH GENE; SMARCB1 GENE; TCF7L1 GENE; UPREGULATION; WNT SIGNALING PATHWAY;

EID: 84908551185     PISSN: None     EISSN: 11769351     Source Type: Journal    
DOI: 10.4137/CIN.S18377     Document Type: Article

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