Quantitative determination of myricetin in rat plasma by ultra performance liquid chromatography tandem mass spectrometry and its absolute bioavailability

Drug Research

Volumn 64, Issue 10, 2013, Pages 516-522

  Dang, Y ^a   Lin, G ^a   Xie, Y ^a   Duan, J ^a   Ma, P ^b   Li, G ^c   Ji, G ^a  

^a SHANGHAI UNIVERSITY OF TRADITIONAL CHINESE MEDICINE   (China)

^b Hospira Inc   (United States)

^c Shanghai TCM Integrated Hospital   (China)

Author keywords

Absolute bioavailability; Myricetin; Pharmacokinetics; Rat plasma; UPLC MS MS

Indexed keywords

ACETIC ACID ETHYL ESTER; BETA GLUCURONIDASE; KAEMPFEROL; MYRICETIN; SULFATASE; FLAVONOID;

ANALYTIC METHOD; ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DRUG BIOAVAILABILITY; DRUG BLOOD LEVEL; LIQUID LIQUID EXTRACTION; MALE; NONHUMAN; QUANTITATIVE ANALYSIS; RAT; TANDEM MASS SPECTROMETRY; ULTRA PERFORMANCE LIQUID CHROMATOGRAPHY; ANIMAL; BIOAVAILABILITY; BLOOD; CALIBRATION; ELECTROSPRAY MASS SPECTROMETRY; INTRAVENOUS DRUG ADMINISTRATION; LIMIT OF DETECTION; LIQUID CHROMATOGRAPHY; ORAL DRUG ADMINISTRATION; REPRODUCIBILITY; SPRAGUE DAWLEY RAT; STANDARD; STANDARDS; STATISTICAL MODEL; VALIDATION STUDY;

ADMINISTRATION, INTRAVENOUS; ADMINISTRATION, ORAL; ANIMALS; BIOLOGICAL AVAILABILITY; CALIBRATION; CHROMATOGRAPHY, LIQUID; FLAVONOIDS; LIMIT OF DETECTION; LINEAR MODELS; MALE; RATS, SPRAGUE-DAWLEY; REFERENCE STANDARDS; REPRODUCIBILITY OF RESULTS; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; TANDEM MASS SPECTROMETRY;

EID: 84908514055     PISSN: 21949379     EISSN: 21949387     Source Type: Journal    
DOI: 10.1055/s-0033-1363220     Document Type: Article

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