Phagocyte-myocyte interactions and consequences during hypoxic wound healing

Cellular Immunology

Volumn 291, Issue 1-2, 2014, Pages 65-73

  Zhang, Shuang ^a   Dehn, Shirley ^a   DeBerge, Matthew ^a   Rhee, Ki Jong ^a   Hudson, Barry ^a   Thorp, Edward B ^a  

^a NORTHWESTERN UNIVERSITY   (United States)

Author keywords

Cardiomyocyte; Monocyte; Myocardial infarction

Indexed keywords

ARTICLE; BLOOD; CELL INTERACTION; GRANULOCYTE FUNCTION; HEART; HEART INFARCTION SIZE; HEART MUSCLE; HUMAN; HYPOXIA; IMMUNOCOMPETENT CELL; INFLAMMATION; MACROPHAGE; MONOCYTE; MUSCLE CELL; NEUTROPHIL; NONHUMAN; PHAGOCYTE; PHAGOCYTOSIS; WOUND HEALING; ANIMAL; CELL HYPOXIA; CYTOLOGY; HEART INFARCTION; HEART MUSCLE CELL; IMMUNOLOGY; MOUSE; PATHOLOGY;

ANIMALS; CELL HYPOXIA; HUMANS; INFLAMMATION; MICE; MYOCARDIAL INFARCTION; MYOCYTES, CARDIAC; PHAGOCYTES; WOUND HEALING;

EID: 84908513897     PISSN: 00088749     EISSN: 10902163     Source Type: Journal    
DOI: 10.1016/j.cellimm.2014.04.006     Document Type: Article

References (144)

1. Akatsu T., Nakamura M., et al. Increased mRNA expression of tumour necrosis factor-alpha and its converting enzyme in circulating leucocytes of patients with acute myocardial infarction. Clin. Sci. (Lond) 2003, 105(1):39-44.
2. Akpek M., Kaya M.G., et al. Relation of neutrophil/lymphocyte ratio to coronary flow to in-hospital major adverse cardiac events in patients with ST-elevated myocardial infarction undergoing primary coronary intervention. Am. J. Cardiol. 2012, 110(5):621-627.
3. Anzai A., Anzai T., et al. Regulatory role of dendritic cells in postinfarction healing and left ventricular remodeling. Circulation 2012, 125(10):1234-1245.
4. Arur S., Uche U.E., et al. Annexin I is an endogenous ligand that mediates apoptotic cell engulfment. Dev. Cell. 2003, 4(4):587-598.
5. Auffray C., Fogg D., et al. Monitoring of blood vessels and tissues by a population of monocytes with patrolling behavior. Science 2007, 317(5838):666-670.
6. Aversano T., Zhou W., et al. A chimeric IgG4 monoclonal antibody directed against CD18 reduces infarct size in a primate model of myocardial ischemia and reperfusion. J. Am. Coll. Cardiol. 1995, 25(3):781-788.
7. Ayata C.K., Ganal S.C., et al. Purinergic P2Y(2) receptors promote neutrophil infiltration and hepatocyte death in mice with acute liver injury. Gastroenterology 2012, 143(6):1620-1629.
8. Bassols A., Massague J. Transforming growth factor beta regulates the expression and structure of extracellular matrix chondroitin/dermatan sulfate proteoglycans. J. Biol. Chem. 1988, 263(6):3039-3045.
9. Belperio J.A., Keane M.P., et al. Critical role for CXCR2 and CXCR2 ligands during the pathogenesis of ventilator-induced lung injury. J. Clin. Invest. 2002, 110(11):1703-1716.
10. Ben-Mordechai T., Holbova R., et al. Macrophage subpopulations are essential for infarct repair with and without stem cell therapy. J. Am. Coll. Cardiol. 2013, 62(20):1890-1901.
11. Birge R.B., Ucker D.S. Innate apoptotic immunity: the calming touch of death. Cell Death Differ. 2008, 15(7):1096-1102.
12. Blume K.E., Soeroes S., et al. Cleavage of annexin A1 by ADAM10 during secondary necrosis generates a monocytic "find-me" signal. J. Immunol. 2012, 188(1):135-145.
13. Bosco M.C., Puppo M., et al. Monocytes and dendritic cells in a hypoxic environment: spotlights on chemotaxis and migration. Immunobiology 2008, 213(9-10):733-749.
14. Bournazou I., Pound J.D., et al. Apoptotic human cells inhibit migration of granulocytes via release of lactoferrin. J. Clin. Invest. 2009, 119(1):20-32.
15. Bowden R.A., Ding Z.M., et al. Role of alpha4 integrin and VCAM-1 in CD18-independent neutrophil migration across mouse cardiac endothelium. Circ. Res. 2002, 90(5):562-569.
16. Braunersreuther V., Pellieux C., et al. Chemokine CCL5/RANTES inhibition reduces myocardial reperfusion injury in atherosclerotic mice. J. Mol. Cell. Cardiol. 2010, 48(4):789-798.
17. Briaud S.A., Ding Z.M., et al. Leukocyte trafficking and myocardial reperfusion injury in ICAM-1/P-selectin-knockout mice. Am. J. Physiol. Heart Circ. Physiol. 2001, 280(1):H60-H67.
18. Bujak M., Dobaczewski M., et al. Induction of the CXC chemokine interferon-gamma-inducible protein 10 regulates the reparative response following myocardial infarction. Circ. Res. 2009, 105(10):973-983.
19. Bujak M., Frangogiannis N.G. The role of TGF-beta signaling in myocardial infarction and cardiac remodeling. Cardiovasc. Res. 2007, 74(2):184-195.
20. Bujak M., Kweon H.J., et al. Aging-related defects are associated with adverse cardiac remodeling in a mouse model of reperfused myocardial infarction. J. Am. Coll. Cardiol. 2008, 51(14):1384-1392.
21. Capoccia B.J., Gregory A.D., et al. Recruitment of the inflammatory subset of monocytes to sites of ischemia induces angiogenesis in a monocyte chemoattractant protein-1-dependent fashion. J. Leukoc. Biol. 2008, 84(3):760-768.
22. Carlin L.M., Stamatiades E.G., et al. Nr4a1-dependent Ly6C(low) monocytes monitor endothelial cells and orchestrate their disposal. Cell 2013, 153(2):362-375.
23. Casanova-Acebes M., Pitaval C., et al. Rhythmic modulation of the hematopoietic niche through neutrophil clearance. Cell 2013, 153(5):1025-1035.
24. Cavanagh S.P., Gough M.J., et al. The role of the neutrophil in ischaemia-reperfusion injury: potential therapeutic interventions. Cardiovasc. Surg. 1998, 6(2):112-118.
25. Chambers S.E., O'Neill C.L., et al. The role of immune-related myeloid cells in angiogenesis. Immunobiology 2013, 218(11):1370-1375.
26. Chekeni F.B., Elliott M.R., et al. Pannexin 1 channels mediate 'find-me' signal release and membrane permeability during apoptosis. Nature 2010, 467(7317):863-867.
27. Chen W., Frangogiannis N.G. The role of inflammatory and fibrogenic pathways in heart failure associated with aging. Heart Fail. Rev. 2010, 15(5):415-422.
28. Chen Y., Corriden R., et al. ATP release guides neutrophil chemotaxis via P2Y2 and A3 receptors. Science 2006, 314(5806):1792-1795.
29. Cheong H.S., Lee S.O., et al. MERTK polymorphisms associated with risk of haematological disorders among Korean SLE patients. Rheumatology 2007, 46(2):209-214.
30. Ciz M., Denev P., et al. Flavonoids inhibit the respiratory burst of neutrophils in mammals. Oxid. Med. Cell. Longev. 2012, 2012:181295.
31. Cleutjens J.P., Blankesteijn W.M., et al. The infarcted myocardium: simply dead tissue, or a lively target for therapeutic interventions. Cardiovasc. Res. 1999, 44(2):232-241.
32. Cochain C., Rodero M.P., et al. Regulation of monocyte subset systemic levels by distinct chemokine receptors controls post-ischaemic neovascularization. Cardiovasc. Res. 2010, 88(1):186-195.
33. Cramer T., Yamanishi Y., et al. HIF-1alpha is essential for myeloid cell-mediated inflammation. Cell 2003, 112(5):645-657.
34. Curran C.S., Demick K.P., et al. Lactoferrin activates macrophages via TLR4-dependent and -independent signaling pathways. Cell. Immunol. 2006, 242(1):23-30.
35. Dahl C.P., Husberg C., et al. Increased production of CXCL16 in experimental and clinical heart failure: a possible role in extracellular matrix remodeling. Circulation. Heart Failure 2009, 2(6):624-632.
36. Daleau P. Lysophosphatidylcholine, a metabolite which accumulates early in myocardium during ischemia, reduces gap junctional coupling in cardiac cells. J. Mol. Cell. Cardiol. 1999, 31(7):1391-1401.
37. Degrossoli A., Giorgio S. Functional alterations in macrophages after hypoxia selection. Exp. Biol. Med. (Maywood) 2007, 232(1):88-95.
38. Dolmatova E., Spagnol G., et al. Cardiomyocyte ATP release through pannexin 1 aids in early fibroblast activation. Am. J. Physiol. Heart Circ. Physiol. 2012, 303(10):14.
39. Dong F., Khalil M., et al. Critical role for leukocyte hypoxia inducible factor-1alpha expression in post-myocardial infarction left ventricular remodeling. Circ. Res. 2010, 106(3):601-610.
40. Dutta P., Courties G., et al. Myocardial infarction accelerates atherosclerosis. Nature 2012, 487(7407):325-329.
41. Elliott K.J., Harriman A., et al. A porphyrin-polyoxometallate bio-inspired mimic for artificial photosynthesis. Phys. Chem. Chem. Phys. 2009, 11(39):8767-8773.
42. Epelman S., Lavine K.J., et al. Embryonic and adult-derived resident cardiac macrophages are maintained through distinct mechanisms at steady state and during inflammation. Immunity 2014, 40(1):91-104.
43. Ergen A.V., Boles N.C., et al. Rantes/Ccl5 influences hematopoietic stem cell subtypes and causes myeloid skewing. Blood 2012, 119(11):2500-2509.
44. Esmann L., Idel C., et al. Phagocytosis of apoptotic cells by neutrophil granulocytes: diminished proinflammatory neutrophil functions in the presence of apoptotic cells. J. Immunol. 2010, 184(1):391-400.
45. Fadok V.A., Bratton D.L., et al. Macrophages that have ingested apoptotic cells in vitro inhibit proinflammatory cytokine production through autocrine/paracrine mechanisms involving TGF-beta, PGE2, and PAF. J. Clin. Invest. 1998, 101(4):890-898.
46. Fiane A.E., Videm V., et al. Mechanism of complement activation and its role in the inflammatory response after thoracoabdominal aortic aneurysm repair. Circulation 2003, 108(7):849-856.
47. Frangogiannis N.G. The immune system and the remodeling infarcted heart: cell biological insights and therapeutic opportunities. J. Cardiovasc. Pharmacol. 2014, 63(3):185-195.
48. Frangogiannis N.G., Mendoza L.H., et al. MCSF expression is induced in healing myocardial infarcts and may regulate monocyte and endothelial cell phenotype. Am. J. Physiol. Heart Circ. Physiol. 2003, 285(2):H483-H492.
49. Frangogiannis N.G., Smith C.W., et al. The inflammatory response in myocardial infarction. Cardiovasc. Res. 2002, 53(1):31-47.
50. Frommhold D., Ludwig A., et al. Sialyltransferase ST3Gal-IV controls CXCR2-mediated firm leukocyte arrest during inflammation. J. Exp. Med. 2008, 205(6):1435-1446.
51. Getts D.R., Terry R.L., et al. Therapeutic inflammatory monocyte modulation using immune-modifying microparticles. Sci. Transl. Med. 2014, 6(219):219ra217.
52. Griendling K.K., FitzGerald G.A. Oxidative stress and cardiovascular injury: Part I: basic mechanisms and in vivo monitoring of ROS. Circulation 2003, 108(16):1912-1916.
53. Hammerman H., Kloner R.A., et al. Dose-dependent effects of short-term methylprednisolone on myocardial infarct extent, scar formation, and ventricular function. Circulation 1983, 68(2):446-452.
54. Hannah S., Mecklenburgh K., et al. Hypoxia prolongs neutrophil survival in vitro. FEBS Lett. 1995, 372(2-3):233-237.
55. Hashimoto D., Chow A., et al. Tissue-resident macrophages self-maintain locally throughout adult life with minimal contribution from circulating monocytes. Immunity 2013, 38(4):792-804.
56. Herr B., Zhou J., et al. The supernatant of apoptotic cells causes transcriptional activation of hypoxia-inducible factor-1alpha in macrophages via sphingosine-1-phosphate and transforming growth factor-beta. Blood 2009, 114(10):2140-2148.
57. Hochreiter-Hufford A., Ravichandran K.S. Clearing the dead: apoptotic cell sensing, recognition, engulfment, and digestion. Cold Spring Harb. Perspect. Biol. 2013, 5(1).
58. Hochreiter-Hufford A.E., Lee C.S., et al. Phosphatidylserine receptor BAI1 and apoptotic cells as new promoters of myoblast fusion. Nature 2013, 497(7448):263-267.
59. Hunt T.K., Twomey P., et al. Respiratory gas tensions and pH in healing wounds. Am. J. Surg. 1967, 114(2):302-307.
60. Imtiyaz H.Z., Williams E.P., et al. Hypoxia-inducible factor 2alpha regulates macrophage function in mouse models of acute and tumor inflammation. J. Clin. Invest. 2010, 120(8):2699-2714.
61. Izmirly P.M., Saxena A., et al. Maternal and fetal factors associated with mortality and morbidity in a multi-racial/ethnic registry of anti-SSA/Ro-associated cardiac neonatal lupus. Circulation 2011, 124(18):1927-1935.
62. Kaikita K., Hayasaki T., et al. Targeted deletion of CC chemokine receptor 2 attenuates left ventricular remodeling after experimental myocardial infarction. Am. J. Pathol. 2004, 165(2):439-447.
63. Kawamoto A., Gwon H.C., et al. Therapeutic potential of ex vivo expanded endothelial progenitor cells for myocardial ischemia. Circulation 2001, 103(5):634-637.
64. Kempf T., Zarbock A., et al. GDF-15 is an inhibitor of leukocyte integrin activation required for survival after myocardial infarction in mice. Nat. Med. 2011, 17(5):581-588.
65. Keyes K.T., Ye Y., et al. Resolvin E1 protects the rat heart against reperfusion injury. Am. J. Physiol. Heart Circ. Physiol. 2010, 299(1):H153-H164.
66. Kong T., Scully M., et al. Identification of Pur alpha as a new hypoxia response factor responsible for coordinated induction of the beta 2 integrin family. J. Immunol. 2007, 179(3):1934-1941.
67. Krishnamurthy P., Rajasingh J., et al. IL-10 inhibits inflammation and attenuates left ventricular remodeling after myocardial infarction via activation of STAT3 and suppression of HuR. Circ. Res. 2009, 104(2):18.
68. Kukielka G.L., Youker K.A., et al. Role of early reperfusion in the induction of adhesion molecules and cytokines in previously ischemic myocardium. Mol. Cell. Biochem. 1995, 147(1-2):5-12.
69. Kyne L., Hausdorff J.M., et al. Neutrophilia and congestive heart failure after acute myocardial infarction. Am. Heart J. 2000, 139(1 Pt 1):94-100.
70. Lauber K., Bohn E., et al. Apoptotic cells induce migration of phagocytes via caspase-3-mediated release of a lipid attraction signal. Cell 2003, 113(6):717-730.
71. Leuschner F., Panizzi P., et al. Angiotensin-converting enzyme inhibition prevents the release of monocytes from their splenic reservoir in mice with myocardial infarction. Circ. Res. 2010, 107(11):1364-1373.
72. Leuschner F., Rauch P.J., et al. Rapid monocyte kinetics in acute myocardial infarction are sustained by extramedullary monocytopoiesis. J. Exp. Med. 2012, 209(1):123-137.
73. Li L., Huang L., et al. IL-17 produced by neutrophils regulates IFN-gamma-mediated neutrophil migration in mouse kidney ischemia-reperfusion injury. J. Clin. Invest. 2010, 120(1):331-342.
74. Libby P. Inflammation in atherosclerosis. Arterioscler. Thromb. Vasc. Biol. 2012, 32(9):2045-2051.
75. Lin M., Jackson P., et al. Matrix metalloproteinase-8 facilitates neutrophil migration through the corneal stromal matrix by collagen degradation and production of the chemotactic peptide Pro-Gly-Pro. Am. J. Pathol. 2008, 173(1):144-153.
76. Lindsey M.L., Gannon J., et al. Selective matrix metalloproteinase inhibition reduces left ventricular remodeling but does not inhibit angiogenesis after myocardial infarction. Circulation 2002, 105(6):753-758.
77. Lloyd-Jones D., Adams R.J., et al. Executive summary: heart disease and stroke statistics-2010 update: a report from the American Heart Association. Circulation 2010, 121(7):948-954.
78. Lou O., Alcaide P., et al. CD99 is a key mediator of the transendothelial migration of neutrophils. J. Immunol. 2007, 178(2):1136-1143.
79. Ma X.L., Weyrich A.S., et al. Monoclonal antibody to L-selectin attenuates neutrophil accumulation and protects ischemic reperfused cat myocardium. Circulation 1993, 88(2):649-658.
80. Ma Y.J., Doni A., et al. Ficolin-1-PTX3 complex formation promotes clearance of altered self-cells and modulates IL-8 production. J. Immunol. 2013, 191(3):1324-1333.
81. Majmudar M.D., Keliher E.J., et al. Monocyte-directed RNAi targeting CCR2 improves infarct healing in atherosclerosis-prone mice. Circulation 2013, 127(20):2038-2046.
82. Marchetti V., Yanes O., et al. Differential macrophage polarization promotes tissue remodeling and repair in a model of ischemic retinopathy. Sci. Rep. 2011, 1:76.
83. Matloubian M., Lo C.G., et al. Lymphocyte egress from thymus and peripheral lymphoid organs is dependent on S1P receptor 1. Nature 2004, 427(6972):355-360.
84. Medina R.J., O'Neill C.L., et al. Myeloid angiogenic cells act as alternative M2 macrophages and modulate angiogenesis through interleukin-8. Mol. Med. 2011, 17(9-10):1045-1055.
85. Meisel S.R., Shapiro H., et al. Increased expression of neutrophil and monocyte adhesion molecules LFA-1 and Mac-1 and their ligand ICAM-1 and VLA-4 throughout the acute phase of myocardial infarction: possible implications for leukocyte aggregation and microvascular plugging. J. Am. Coll. Cardiol. 1998, 31(1):120-125.
86. Meissner J., Irfan A., et al. Use of neutrophil count in early diagnosis and risk stratification of AMI. Am. J. Med. 2011, 124(6):534-542.
87. Muller W.A. The role of PECAM-1 (CD31) in leukocyte emigration: studies in vitro and in vivo. J. Leukoc. Biol. 1995, 57(4):523-528.
88. Munoz X., Sumoy L., et al. Human vitamin K-dependent GAS6: gene structure, allelic variation, and association with stroke. Hum. Mutat. 2004, 23(5):506-512.
89. Nahrendorf M., Swirski F.K. Monocyte and macrophage heterogeneity in the heart. Circ. Res. 2013, 112(12):1624-1633.
90. Nahrendorf M., Swirski F.K., et al. The healing myocardium sequentially mobilizes two monocyte subsets with divergent and complementary functions. J. Exp. Med. 2007, 204(12):3037-3047.
91. Nie H.J., Tian Y.M., et al. Changes of erythrocyte deformability in rats acclimatized to hypoxia and its molemechanism. Zhongguo Ying Yong Sheng Li Xue Za Zhi 2011, 27(1):23-28.
92. Novak M.L., Weinheimer-Haus E.M., et al. Macrophage activation and skeletal muscle healing following traumatic injury. J. Pathol. 2014, 232(3):344-355.
93. O'Donoghue M., Morrow D.A., et al. Association between baseline neutrophil count, clopidogrel therapy, and clinical and angiographic outcomes in patients with ST-elevation myocardial infarction receiving fibrinolytic therapy. Eur. Heart J. 2008, 29(8):984-991.
94. Oda T., Hirota K., et al. Activation of hypoxia-inducible factor 1 during macrophage differentiation. Am. J. Physiol. Cell Physiol. 2006, 291(1):C104-C113.
95. Panizzi P., Swirski F.K., et al. Impaired infarct healing in atherosclerotic mice with Ly-6C(hi) monocytosis. J. Am. Coll. Cardiol. 2010, 55(15):1629-1638.
96. Park Y.J., Liu G., et al. PAI-1 inhibits neutrophil efferocytosis. Proc. Natl. Acad. Sci. USA 2008, 105(33):11784-11789.
97. Peter C., Waibel M., et al. Migration to apoptotic "find-me" signals is mediated via the phagocyte receptor G2A. J. Biol. Chem. 2008, 283(9):5296-5305.
98. Pinto A.R., Paolicelli R., et al. An abundant tissue macrophage population in the adult murine heart with a distinct alternatively-activated macrophage profile. PLoS ONE 2012, 7(5):10.
99. Ravichandran K.S. Beginnings of a good apoptotic meal: the find-me and eat-me signaling pathways. Immunity 2011, 35(4):445-455.
100. Rogers N.M., Yao M., et al. Activated CD47 regulates multiple vascular and stress responses: implications for acute kidney injury and its management. Am. J. Physiol. Renal. Physiol. 2012, 303(8):F1117-F1125.
101. Romson J.L., Hook B.G., et al. Reduction of the extent of ischemic myocardial injury by neutrophil depletion in the dog. Circulation 1983, 67(5):1016-1023.
102. Rudolph V., Goldmann B.U., et al. Diagnostic value of MPO plasma levels in patients admitted for suspected myocardial infarction. Int. J. Cardiol. 2011, 153(3):267-271.
103. Sather S., Kenyon K.D., et al. A soluble form of the Mer receptor tyrosine kinase inhibits macrophage clearance of apoptotic cells and platelet aggregation. Blood 2007, 109(3):1026-1033.
104. Scheerer N., Dehne N., et al. Myeloid hypoxia-inducible factor-1alpha is essential for skeletal muscle regeneration in mice. J. Immunol. 2013, 191(1):407-414.
105. Schwab J.M., Chiang N., et al. Resolvin E1 and protectin D1 activate inflammation-resolution programmes. Nature 2007, 447(7146):869-874.
106. Serhan C.N., Maddox J.F., et al. Design of lipoxin A4 stable analogs that block transmigration and adhesion of human neutrophils. Biochemistry 1995, 34(44):14609-14615.
107. Serhan C.N., Savill J. Resolution of inflammation: the beginning programs the end. Nat. Immunol. 2005, 6(12):1191-1197.
108. Shantsila E., Lip G.Y. Monocyte diversity in myocardial infarction. J. Am. Coll. Cardiol. 2009, 54(2):139-142.
109. Shantsila E., Wrigley B., et al. Immunophenotypic characterization of human monocyte subsets: possible implications for cardiovascular disease pathophysiology. Journal of thrombosis and haemostasis: JTH 2011, 9(5):1056-1066.
110. Shingu M., Nonaka S., et al. Activation of complement in normal serum by hydrogen peroxide and hydrogen peroxide-related oxygen radicals produced by activated neutrophils. Clin. Exp. Immunol. 1992, 90(1):72-78.
111. Singer I.I., Tian M., et al. Sphingosine-1-phosphate agonists increase macrophage homing, lymphocyte contacts, and endothelial junctional complex formation in murine lymph nodes. J. Immunol. 2005, 175(11):7151-7161.
112. Singh M.V., Swaminathan P.D., et al. MyD88 mediated inflammatory signaling leads to CaMKII oxidation, cardiac hypertrophy and death after myocardial infarction. J. Mol. Cell. Cardiol. 2012, 52(5):1135-1144.
113. Soehnlein O., Weber C., et al. Neutrophil granule proteins tune monocytic cell function. Trends Immunol. 2009, 30(11):538-546.
114. Stark M.A., Huo Y., et al. Phagocytosis of apoptotic neutrophils regulates granulopoiesis via IL-23 and IL-17. Immunity 2005, 22(3):285-294.
115. Swinnen M., Vanhoutte D., et al. Absence of thrombospondin-2 causes age-related dilated cardiomyopathy. Circulation 2009, 120(16):1585-1597.
116. Swirski F.K., Nahrendorf M., et al. Identification of splenic reservoir monocytes and their deployment to inflammatory sites. Science 2009, 325(5940):612-616.
117. Swirski F.K., Robbins C.S. Neutrophils usher monocytes into sites of inflammation. Circ. Res. 2013, 112(5):744-745.
118. Tabas I. Consequences and therapeutic implications of macrophage apoptosis in atherosclerosis: the importance of lesion stage and phagocytic efficiency. Arterioscler. Thromb. Vasc. Biol. 2005, 25(11):2255-2264.
119. Tabas I., Glass C.K. Anti-inflammatory therapy in chronic disease: challenges and opportunities. Science 2013, 339(6116):166-172.
120. Takano T., Clish C.B., et al. Neutrophil-mediated changes in vascular permeability are inhibited by topical application of aspirin-triggered 15-epi-lipoxin A4 and novel lipoxin B4 stable analogues. J. Clin. Invest. 1998, 101(4):819-826.
121. Takeda Y., Costa S., et al. Macrophage skewing by Phd2 haplodeficiency prevents ischaemia by inducing arteriogenesis. Nature 2011, 479(7371):122-126.
122. Tao Z.Y., Cavasin M.A., et al. Temporal changes in matrix metalloproteinase expression and inflammatory response associated with cardiac rupture after myocardial infarction in mice. Life Sci. 2004, 74(12):1561-1572.
123. Tapp L.D., Shantsila E., et al. The CD14++CD16+ monocyte subset and monocyte-platelet interactions in patients with ST-elevation myocardial infarction. J. Thromb. Haemostasis 2012, 10(7):1231-1241.
124. Thompson A.A., Binham J., et al. Hypoxia, the HIF pathway and neutrophilic inflammatory responses. Biol. Chem. 2013, 394(4):471-477.
125. Thorp E., Vaisar T., et al. Shedding of the MER tyrosine kinase receptor is mediated by ADAM17 through a pathway involving reactive oxygen species, protein kinase {delta}, and P38 map kinase. J. Biol. Chem. 2011, 286(38):33335-33344.
126. Thorp E.B. Contrasting inflammation resolution during atherosclerosis and post myocardial infarction at the level of monocyte/macrophage phagocytic clearance. Front. Immunol. 2012, 3:39.
127. Truman L.A., Ford C.A., et al. CX3CL1/fractalkine is released from apoptotic lymphocytes to stimulate macrophage chemotaxis. Blood 2008, 112(13):5026-5036.
128. Tsai R.K., Discher D.E. Inhibition of "self" engulfment through deactivation of myosin-II at the phagocytic synapse between human cells. J. Cell Biol. 2008, 180(5):989-1003.
129. Tsujioka H., Imanishi T., et al. Impact of heterogeneity of human peripheral blood monocyte subsets on myocardial salvage in patients with primary acute myocardial infarction. J. Am. Coll. Cardiol. 2009, 54(2):130-138.
130. Uderhardt S., Herrmann M., et al. 12/15-lipoxygenase orchestrates the clearance of apoptotic cells and maintains immunologic tolerance. Immunity 2012, 36(5):834-846.
131. Vandivier R.W., Henson P.M., et al. Burying the dead: the impact of failed apoptotic cell removal (efferocytosis) on chronic inflammatory lung disease. Chest 2006, 129(6):1673-1682.
132. Vasilyev N., Williams T., et al. Myeloperoxidase-generated oxidants modulate left ventricular remodeling but not infarct size after myocardial infarction. Circulation 2005, 112(18):2812-2820.
133. Walmsley S.R., Chilvers E.R., et al. Prolyl hydroxylase 3 (PHD3) is essential for hypoxic regulation of neutrophilic inflammation in humans and mice. J. Clin. Invest. 2011, 121(3):1053-1063.
134. Wan E., Yeap X.Y., et al. Enhanced efferocytosis of apoptotic cardiomyocytes through myeloid-epithelial-reproductive tyrosine kinase links acute inflammation resolution to cardiac repair after infarction. Circ. Res. 2013, 113(8):1004-1012.
135. Wantha S., Alard J.E., et al. Neutrophil-derived cathelicidin promotes adhesion of classical monocytes. Circ. Res. 2013, 112(5):792-801.
136. Werno C., Menrad H., et al. Knockout of HIF-1alpha in tumor-associated macrophages enhances M2 polarization and attenuates their pro-angiogenic responses. Carcinogenesis 2010, 31(10):1863-1872.
137. Whelan R.S., Kaplinskiy V., et al. Cell death in the pathogenesis of heart disease: mechanisms and significance. Annu. Rev. Physiol. 2010, 72:19-44.
138. Xiong M., Elson G., et al. Production of vascular endothelial growth factor by murine macrophages: regulation by hypoxia, lactate, and the inducible nitric oxide synthase pathway. Am. J. Pathol. 1998, 153(2):587-598.
139. Yan X., Anzai A., et al. Temporal dynamics of cardiac immune cell accumulation following acute myocardial infarction. J. Mol. Cell. Cardiol. 2013, 62:24-35.
140. Yang Z., Zingarelli B., et al. Crucial role of endogenous interleukin-10 production in myocardial ischemia/reperfusion injury. Circulation 2000, 101(9):1019-1026.
141. Yndestad A., Landro L., et al. Increased systemic and myocardial expression of neutrophil gelatinase-associated lipocalin in clinical and experimental heart failure. Eur. Heart J. 2009, 30(10):1229-1236.
142. Zakharova E.E., Korneeva V.A., et al. Psychrophilic sulfur-reducing bacterium from aerobic Black Sea waters. Mikrobiologiia 2012, 81(6):812-814.
143. Zhou J., Dehne N., et al. Nitric oxide causes macrophage migration via the HIF-1-stimulated small GTPases Cdc42 and Rac1. Free Rad. Biol. Med. 2009, 47(6):741-749.
144. Zouggari Y., Ait-Oufella H., et al. B lymphocytes trigger monocyte mobilization and impair heart function after acute myocardial infarction. Nat. Med. 2013, 19(10):1273-1280.