Familial hypertrophic cardiomyopathy: Functional variance among individual cardiomyocytes as a trigger of fhc-phenotype development

Frontiers in Physiology

Volumn 5, Issue OCT, 2014, Pages

  Brenner, Bernhard ^a   Seebohm, Benjamin ^a   Tripathi, Snigdha ^a   Montag, Judith ^a   Kraft, Theresia ^a  

^a HANNOVER MEDICAL SCHOOL   (Germany)

Author keywords

Allelic imbalance; Calcium sensitivity of cardiomyocytes; Calcium sensitivity of muscle fibers; Converter domain of myosin head; Interstitial fibrosis; MYH7 mutations; Myocyte disarray; Myosin head stiffness

Indexed keywords

ADENOSINE TRIPHOSPHATASE; CALCIUM ION; MYOSIN HEAVY CHAIN BETA; TROPONIN I;

AMINO ACID SEQUENCE; ANIMAL TISSUE; ARTICLE; CALCIUM ACTIVATION; CALCIUM SENSITIVITY; CHEMICAL REACTION; CONTROLLED STUDY; FAMILIAL HYPERTROPHIC CARDIOMYOPATHY; GENE; GENE EXPRESSION; GENETIC ASSOCIATION; GENETIC VARIABILITY; HEART CONTRACTION; HEART MUSCLE CELL; HUMAN; HUMAN TISSUE; MISSENSE MUTATION; MYH7 GENE; NONHUMAN; PHENOTYPE; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; SENSITIVITY AND SENSIBILITY; SIGNAL TRANSDUCTION; SOLEUS MUSCLE;

EID: 84908463504     PISSN: None     EISSN: 1664042X     Source Type: Journal    
DOI: 10.3389/fphys.2014.00392     Document Type: Article

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