The role of angiotensin II, endothelin-1 and transforming growth factor-β as autocrine/paracrine mediators of stretch-induced cardiomyocyte hypertrophy

Molecular and Cellular Biochemistry

Volumn 218, Issue 1-2, 2001, Pages 113-124

  Van Wamel, A J E T ^a   Ruwhof, C ^a   Van Der Valk Kokshoorn, L E J M ^a   Schriern, P I ^a   Van Der Laarse, A ^a  

^a LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

Autocrine paracrine mediators; Cardiomyocytes; Endothelial cells; Fibroblasts; Gene expression; Hypertrophy; Stretch; Vascular smooth muscle cells

Indexed keywords

ANGIOTENSIN; ANGIOTENSIN RECEPTOR ANTAGONIST; ATRIAL NATRIURETIC FACTOR; BQ 610; ENDOTHELIN 1; ENDOTHELIN A RECEPTOR ANTAGONIST; LOSARTAN; MESSENGER RNA; PROTEIN C FOS; TRANSFORMING GROWTH FACTOR BETA;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; AUTOCRINE EFFECT; CELL INTERACTION; CELL TYPE; CONTROLLED STUDY; CULTURE MEDIUM; ENDOTHELIUM CELL; FIBROBLAST; GENE EXPRESSION; HEART MUSCLE CELL; HEART VENTRICLE HYPERTROPHY; MARKER GENE; MECHANICAL STRESS; MEDIATOR; MUSCLE STRETCHING; NEWBORN; NONHUMAN; ONCOGENE C FOS; PARACRINE SIGNALING; PHENOTYPE; PROTEIN EXPRESSION; PROTO ONCOGENE; RAT; SMOOTH MUSCLE FIBER; VASCULAR SMOOTH MUSCLE;

ANGIOTENSIN II; ANIMALS; CARDIOMEGALY; CELLS, CULTURED; CULTURE MEDIA, CONDITIONED; ENDOTHELIN-1; ENDOTHELIUM, VASCULAR; FIBROBLASTS; GENE EXPRESSION; GENES, FOS; MUSCLE, SMOOTH, VASCULAR; MYOCARDIUM; RATS; RATS, WISTAR; RNA, MESSENGER; STRESS, MECHANICAL; TRANSFORMING GROWTH FACTOR BETA; VASOCONSTRICTOR AGENTS;

ANIMALIA;

EID: 0035072921     PISSN: 03008177     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1007279700705     Document Type: Article

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