Dioscin attenuates hepatic ischemia-reperfusion injury in rats through inhibition of oxidative-nitrative stress, inflammation and apoptosis

Transplantation

Volumn 98, Issue 6, 2014, Pages 604-611

  Tao, Xufeng ^a   Wan, Xianyao ^a   Xu, Youwei ^a   Xu, Lina ^a   Qi, Yan ^a   Yin, Lianhong ^a   Han, Xu ^a   Lin, Yuan ^a   Peng, Jinyong ^a  

^a DALIAN MEDICAL UNIVERSITY   (China)

Author keywords

Apoptosis; Dioscin; Hepatic I R injury; Inflammation; Natural product

Indexed keywords

ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; CASPASE 3; CATALASE; CYCLOOXYGENASE 2; CYTOCHROME P450 2E1; DIOSCIN; FAS ANTIGEN; FAS LIGAND; GLUTATHIONE; GLUTATHIONE PEROXIDASE; HIGH MOBILITY GROUP B1 PROTEIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERCELLULAR ADHESION MOLECULE 1; INTERLEUKIN 1BETA; INTERLEUKIN 6; LIVER PROTECTIVE AGENT; MACROPHAGE INFLAMMATORY PROTEIN 1ALPHA; MACROPHAGE INFLAMMATORY PROTEIN 2; MALONALDEHYDE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; PROTEIN BAK; PROTEIN P53; SUPEROXIDE DISMUTASE; TRANSCRIPTION FACTOR AP 1; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; UNINDEXED DRUG; ANTIOXIDANT; DIOSGENIN; NITROGEN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BLOOD LEVEL; CONTROLLED STUDY; DNA FRAGMENTATION; DRUG EFFECT; DRUG EFFICACY; DRUG MECHANISM; DRUG RESPONSE; ENZYME ACTIVITY; ENZYME PHOSPHORYLATION; GENE EXPRESSION; INFLAMMATION; LIVER ISCHEMIA; MALE; NITRATIVE STRESS; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RAT; REPERFUSION INJURY; SURVIVAL RATE; UPREGULATION; ANALOGS AND DERIVATIVES; ANIMAL; BLOOD; DOSE RESPONSE; ISCHEMIA; LIVER; METABOLISM; PHOSPHORYLATION; TIME; WISTAR RAT;

ALANINE TRANSAMINASE; ANIMALS; ANTIOXIDANTS; APOPTOSIS; ASPARTATE AMINOTRANSFERASES; DIOSGENIN; DOSE-RESPONSE RELATIONSHIP, DRUG; INFLAMMATION; LIVER; MALE; NITROGEN; OXIDATIVE STRESS; PHOSPHORYLATION; RATS; RATS, WISTAR; REPERFUSION INJURY; TIME FACTORS; WARM ISCHEMIA;

EID: 84908437770     PISSN: 00411337     EISSN: None     Source Type: Journal    
DOI: 10.1097/TP.0000000000000262     Document Type: Article

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