Mitochondrial reactive oxygen species generation triggers inflammatory response and tissue injury associated with hepatic ischemiareperfusion: Therapeutic potential of mitochondrially targeted antioxidants

Free Radical Biology and Medicine

Volumn 53, Issue 5, 2012, Pages 1123-1138

  Mukhopadhyay, Partha ^a   Horváth, Bela ^a,e   Zsengeller, Zsuzsanna ^c   Bátkai, Sándor ^a   Cao, Zongxian ^a   Kechrid, Malek ^a   Holovac, Eileen ^a   Erdlyi, Katalin ^a   Tanchian, Galin ^a   Liaudet, Lucas ^d   Stillman, Isaac E ^c   Joseph, Joy ^b   Kalyanaraman, Balaraman ^b   Pacher, Pál ^a  

^a NATIONAL INSTITUTE ON ALCOHOL ABUSE AND ALCOHOLISM   (United States)

^b FREE RADICAL RESEARCH CENTER   (United States)

^c HARVARD MEDICAL SCHOOL   (United States)

^d LAUSANNE UNIVERSITY HOSPITAL   (Switzerland)

^e SEMMELWEIS UNIVERSITY   (Hungary)

Author keywords

Antioxidants; Free radicals; Ischemiareperfusion; Oxidative stress; Reactive oxygen and nitrogen species

Indexed keywords

3 NITROTYROSINE; ANTIOXIDANT; CXCL2 CHEMOKINE; MACROPHAGE INFLAMMATORY PROTEIN 1ALPHA; MALONALDEHYDE; MITO CP; MITOQ; REACTIVE OXYGEN METABOLITE; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL DEATH; CELL INFILTRATION; CONTROLLED STUDY; HISTOPATHOLOGY; INFLAMMATION; LIVER; LIVER CELL DAMAGE; LIVER DYSFUNCTION; LIVER ISCHEMIA; LIVER MITOCHONDRION; MALE; MITOCHONDRION; MOUSE; NEUTROPHIL CHEMOTAXIS; NITRATIVE STRESS; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; REPERFUSION INJURY; TISSUE INJURY;

ANIMALS; ANTIOXIDANTS; CYCLIC N-OXIDES; DOSE-RESPONSE RELATIONSHIP, DRUG; INFLAMMATION; LIVER DISEASES; MALE; MICE; MICE, INBRED C57BL; MITOCHONDRIA, LIVER; ORGANOPHOSPHORUS COMPOUNDS; OXIDATIVE STRESS; REACTIVE OXYGEN SPECIES; REPERFUSION INJURY; UBIQUINONE;

VASCONCELLEA CANDICANS;

EID: 84864956266     PISSN: 08915849     EISSN: 18734596     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2012.05.036     Document Type: Article

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