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Volumn 4, Issue 10, 2014, Pages 2013-2021

The alternative oxidase AOX does not rescue the phenotype of tko25t mutant flies

Author keywords

Developmental delay; Gene therapy; Mitochondrial disease; Oxidative phosphorylation; Seizures

Indexed keywords

OXIDOREDUCTASE; PROTEIN NDI1; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE; UNCLASSIFIED DRUG; ADENOSINE TRIPHOSPHATE; ALTERNATIVE OXIDASE; BETA CAROTENE; CITROXANTHIN; DROSOPHILA PROTEIN; HORMONE ANTAGONIST; MIFEPRISTONE; MITOCHONDRIAL PROTEIN; MITOCHONDRIAL RIBOSOMAL PROTEIN S12; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE (UBIQUINONE); RIBOSOME PROTEIN; VEGETABLE PROTEIN;

EID: 84908433164     PISSN: None     EISSN: 21601836     Source Type: Journal    
DOI: 10.1534/g3.114.013946     Document Type: Article
Times cited : (20)

References (37)
  • 1
    • 84896351554 scopus 로고    scopus 로고
    • Interrelation between protein synthesis, proteostasis and life span
    • Arnsburg, K., and J. Kirstein-Miles, 2014 Interrelation between protein synthesis, proteostasis and life span. Curr. Genomics 15: 66-75.
    • (2014) Curr. Genomics , vol.15 , pp. 66-75
    • Arnsburg, K.1    Kirstein-Miles, J.2
  • 2
    • 34548644716 scopus 로고    scopus 로고
    • Sex differences in survival and mitochondrial bioenergetics during aging in Drosophila
    • Ballard, J. W., R. G. Melvin, J. T. Muller, and S. D. Katewa, 2007 Sex differences in survival and mitochondrial bioenergetics during aging in Drosophila. Aging Cell 6: 699-708.
    • (2007) Aging Cell , vol.6 , pp. 699-708
    • Ballard, J.W.1    Melvin, R.G.2    Muller, J.T.3    Katewa, S.D.4
  • 3
    • 84867181855 scopus 로고    scopus 로고
    • A cytoplasmic suppressor of a nuclear mutation affecting mitochondrial functions in Drosophila
    • Chen, S., M. T. Oliveira, A. Sanz, E. Kemppainen, A. Fukuoh et al., 2012 A cytoplasmic suppressor of a nuclear mutation affecting mitochondrial functions in Drosophila. Genetics 192: 483-493.
    • (2012) Genetics , vol.192 , pp. 483-493
    • Chen, S.1    Oliveira, M.T.2    Sanz, A.3    Kemppainen, E.4    Fukuoh, A.5
  • 4
    • 84897456295 scopus 로고    scopus 로고
    • Engineering the alternative oxidase gene to better understand and counteract mitochondrial defects: State of the art and perspectives
    • El-Khoury, R., K. K. Kemppainen, E. Dufour, M. Szibor, H. T. Jacobs et al., 2014 Engineering the alternative oxidase gene to better understand and counteract mitochondrial defects: State of the art and perspectives. Br. J. Pharmacol. 171: 2243-2249.
    • (2014) Br. J. Pharmacol. , vol.171 , pp. 2243-2249
    • El-Khoury, R.1    Kemppainen, K.K.2    Dufour, E.3    Szibor, M.4    Jacobs, H.T.5
  • 5
    • 0028500356 scopus 로고
    • Altered mechanoreceptor response in Drosophila bang-sensitive mutants
    • Engel, J. E., and C. F. Wu, 1994 Altered mechanoreceptor response in Drosophila bang-sensitive mutants. J. Comp. Physiol. A. 175: 267-78.
    • (1994) J. Comp. Physiol. A. , vol.175 , pp. 267-278
    • Engel, J.E.1    Wu, C.F.2
  • 6
    • 33746384132 scopus 로고    scopus 로고
    • Metabolic disruption in Drosophila bang-sensitive seizure mutants
    • Fergestad, T., B. Bostwick, and B. Ganetzky, 2006 Metabolic disruption in Drosophila bang-sensitive seizure mutants. Genetics 173: 1357-1364.
    • (2006) Genetics , vol.173 , pp. 1357-1364
    • Fergestad, T.1    Bostwick, B.2    Ganetzky, B.3
  • 7
    • 40849084018 scopus 로고    scopus 로고
    • Neuropathology in Drosophila mutants with increased seizure susceptibility
    • Fergestad, T., L. Olson, K. P. Patel, R. Miller, M. J. Palladino et al., 2008 Neuropathology in Drosophila mutants with increased seizure susceptibility. Genetics 178: 947-956.
    • (2008) Genetics , vol.178 , pp. 947-956
    • Fergestad, T.1    Olson, L.2    Patel, K.P.3    Miller, R.4    Palladino, M.J.5
  • 8
    • 65349167880 scopus 로고    scopus 로고
    • Expression of the Ciona intestinalis alternative oxidase (AOX) in Drosophila complements defects in mitochondrial oxidative phosphorylation
    • Fernández-Ayala, D. J., A. Sanz, S. Vartiainen, K. K. Kemppainen, M. Babusiak et al., 2009 Expression of the Ciona intestinalis alternative oxidase (AOX) in Drosophila complements defects in mitochondrial oxidative phosphorylation. Cell Metab. 9: 449-460.
    • (2009) Cell Metab. , vol.9 , pp. 449-460
    • Fernández-Ayala, D.J.1    Sanz, A.2    Vartiainen, S.3    Kemppainen, K.K.4    Babusiak, M.5
  • 10
    • 84878138385 scopus 로고    scopus 로고
    • Mitonuclear protein imbalance as a conserved longevity mechanism
    • Houtkooper, R. H., L. Mouchiroud, D. Ryu, N. Moullan, E. Katsyuba et al., 2013 Mitonuclear protein imbalance as a conserved longevity mechanism. Nature 497: 451-457.
    • (2013) Nature , vol.497 , pp. 451-457
    • Houtkooper, R.H.1    Mouchiroud, L.2    Ryu, D.3    Moullan, N.4    Katsyuba, E.5
  • 11
    • 84861749376 scopus 로고    scopus 로고
    • Alternative oxidase rescues mitochondria-mediated dopaminergic cell loss in Drosophila
    • Humphrey, D. M., R. B. Parsons, Z. N. Ludlow, T. Riemensperger, G. Esposito et al., 2012 Alternative oxidase rescues mitochondria-mediated dopaminergic cell loss in Drosophila. Hum. Mol. Genet. 21: 2698-2712.
    • (2012) Hum. Mol. Genet. , vol.21 , pp. 2698-2712
    • Humphrey, D.M.1    Parsons, R.B.2    Ludlow, Z.N.3    Riemensperger, T.4    Esposito, G.5
  • 12
    • 0037869565 scopus 로고    scopus 로고
    • Altered drug resistance and recovery from paralysis in Drosophila melanogaster with a deficient histamine-gated chloride channel
    • Iovchev, M., P. Kodrov, A. J. Wolstenholme, W. L. Pak, and E. P. Semenov, 2002 Altered drug resistance and recovery from paralysis in Drosophila melanogaster with a deficient histamine-gated chloride channel. J. Neurogenet. 16: 249-261.
    • (2002) J. Neurogenet. , vol.16 , pp. 249-261
    • Iovchev, M.1    Kodrov, P.2    Wolstenholme, A.J.3    Pak, W.L.4    Semenov, E.P.5
  • 13
    • 12944315071 scopus 로고    scopus 로고
    • Drugresistant Drosophila indicate glutamate-gated chloride channels are targets for the antiparasitics nodulisporic acid and ivermectin
    • Kane, N. S., B. Hirschberg, S. Qian, D. Hunt, B. Thomas et al., 2000 Drugresistant Drosophila indicate glutamate-gated chloride channels are targets for the antiparasitics nodulisporic acid and ivermectin. Proc. Natl. Acad. Sci. USA 97: 13949-13954.
    • (2000) Proc. Natl. Acad. Sci. USA , vol.97 , pp. 13949-13954
    • Kane, N.S.1    Hirschberg, B.2    Qian, S.3    Hunt, D.4    Thomas, B.5
  • 14
    • 70149110198 scopus 로고    scopus 로고
    • Phenotypic suppression of the Drosophila mitochondrial disease-like mutant tko25t by duplication of the mutant gene in its natural chromosomal context
    • Kemppainen, E, D. J. Fernández-Ayala, L. C. Galbraith, and K. M. C. O'Dell, and H. T. Jacobs, 2009 Phenotypic suppression of the Drosophila mitochondrial disease-like mutant tko25t by duplication of the mutant gene in its natural chromosomal context. Mitochondrion 9: 353-363.
    • (2009) Mitochondrion , vol.9 , pp. 353-363
    • Kemppainen, E.1    Fernández-Ayala, D.J.2    Galbraith, L.C.3    O'Dell, K.M.C.4    Jacobs, H.T.5
  • 15
    • 84897880940 scopus 로고    scopus 로고
    • Expression of alternative oxidase in Drosophila ameliorates diverse phenotypes due to cytochrome oxidase deficiency
    • Kemppainen, K. K., J. Rinne, A. Sriram, M. Lakanmaa, A. Zeb et al., 2014 Expression of alternative oxidase in Drosophila ameliorates diverse phenotypes due to cytochrome oxidase deficiency. Hum. Mol. Genet. 23: 2078-2093.
    • (2014) Hum. Mol. Genet. , vol.23 , pp. 2078-2093
    • Kemppainen, K.K.1    Rinne, J.2    Sriram, A.3    Lakanmaa, M.4    Zeb, A.5
  • 16
    • 0037114955 scopus 로고    scopus 로고
    • Electroconvulsive seizure behavior in Drosophila: analysis of the physiological repertoire underlying a stereotyped action pattern in bang-sensitive mutants
    • Lee, J., and C. F. Wu, 2002 Electroconvulsive seizure behavior in Drosophila: analysis of the physiological repertoire underlying a stereotyped action pattern in bang-sensitive mutants. J. Neurosci. 22: 11065-11079.
    • (2002) J. Neurosci. , vol.22 , pp. 11065-11079
    • Lee, J.1    Wu, C.F.2
  • 17
    • 77949899075 scopus 로고    scopus 로고
    • Flightless flies: Drosophila models of neuromuscular disease
    • Lloyd, T. E., and J. P. Taylor, 2010 Flightless flies: Drosophila models of neuromuscular disease. Ann. N. Y. Acad. Sci. 1184: e1-e20.
    • (2010) Ann. N. Y. Acad. Sci. , vol.1184 , pp. e1-e20
    • Lloyd, T.E.1    Taylor, J.P.2
  • 18
    • 66149135641 scopus 로고    scopus 로고
    • Drosophila models of neurodegenerative diseases
    • Lu, B., and H. Vogel, 2009 Drosophila models of neurodegenerative diseases. Annu. Rev. Pathol. 4: 315-342.
    • (2009) Annu. Rev. Pathol. , vol.4 , pp. 315-342
    • Lu, B.1    Vogel, H.2
  • 19
    • 68249124533 scopus 로고    scopus 로고
    • Alternative oxidase in animals: unique characteristics and taxonomic distribution
    • McDonald, A. E., G. C. Vanlerberghe, and J. F. Staples, 2009 Alternative oxidase in animals: unique characteristics and taxonomic distribution. J. Exp. Biol. 212: 2627-2634.
    • (2009) J. Exp. Biol. , vol.212 , pp. 2627-2634
    • McDonald, A.E.1    Vanlerberghe, G.C.2    Staples, J.F.3
  • 20
    • 84880517634 scopus 로고    scopus 로고
    • The NAD(+)/sirtuin pathway modulates longevity through activation of mitochondrial UPR and FOXO signaling
    • Mouchiroud, L., R. H. Houtkooper, N. Moullan, E. Katsyuba, D. Ryu et al., 2013 The NAD(+)/sirtuin pathway modulates longevity through activation of mitochondrial UPR and FOXO signaling. Cell 154: 430-441.
    • (2013) Cell , vol.154 , pp. 430-441
    • Mouchiroud, L.1    Houtkooper, R.H.2    Moullan, N.3    Katsyuba, E.4    Ryu, D.5
  • 21
    • 77955847307 scopus 로고    scopus 로고
    • Modeling mitochondrial encephalomyopathy in Drosophila
    • Palladino, M. J., 2010 Modeling mitochondrial encephalomyopathy in Drosophila. Neurobiol. Dis. 40: 40-45.
    • (2010) Neurobiol. Dis. , vol.40 , pp. 40-45
    • Palladino, M.J.1
  • 22
    • 79951548110 scopus 로고    scopus 로고
    • Drosophila as a model for epilepsy: bss is a gain-of-function mutation in the para sodium channel gene that leads to seizures
    • Parker, L., M. Padilla, Y. Du, K. Dong, and M. A. Tanouye, 2011 Drosophila as a model for epilepsy: bss is a gain-of-function mutation in the para sodium channel gene that leads to seizures. Genetics 187: 523-534.
    • (2011) Genetics , vol.187 , pp. 523-534
    • Parker, L.1    Padilla, M.2    Du, Y.3    Dong, K.4    Tanouye, M.A.5
  • 23
    • 0029088206 scopus 로고
    • Seizures and failures in the giant fiber pathway of Drosophila bang-sensitive paralytic mutants
    • Pavlidis, P., and M. A. Tanouye, 1995 Seizures and failures in the giant fiber pathway of Drosophila bang-sensitive paralytic mutants. J. Neurosci. 15: 5810-5819.
    • (1995) J. Neurosci. , vol.15 , pp. 5810-5819
    • Pavlidis, P.1    Tanouye, M.A.2
  • 24
    • 0028108924 scopus 로고
    • The Drosophila easily shocked gene: a mutation in a phospholipid synthetic pathway causes seizure, neuronal failure, and paralysis
    • Pavlidis, P., M. Ramaswami, and M. A. Tanouye, 1994 The Drosophila easily shocked gene: a mutation in a phospholipid synthetic pathway causes seizure, neuronal failure, and paralysis. Cell 79: 23-33.
    • (1994) Cell , vol.79 , pp. 23-33
    • Pavlidis, P.1    Ramaswami, M.2    Tanouye, M.A.3
  • 26
    • 0023663056 scopus 로고
    • The tko locus, site of a behavioral mutation in D. melanogaster, codes for a protein homologous to prokaryotic ribosomal protein S12
    • Royden, C. S., V. Pirrotta, and L. Y. Jan, 1987 The tko locus, site of a behavioral mutation in D. melanogaster, codes for a protein homologous to prokaryotic ribosomal protein S12. Cell 51: 165-173.
    • (1987) Cell , vol.51 , pp. 165-173
    • Royden, C.S.1    Pirrotta, V.2    Jan, L.Y.3
  • 28
    • 77953163811 scopus 로고    scopus 로고
    • Mitochondrial ROS production correlates with, but does not directly regulate lifespan in Drosophila
    • Sanz, A., D. J. Fernández-Ayala, R. K. Stefanatos, and H. T. Jacobs, 2010a Mitochondrial ROS production correlates with, but does not directly regulate lifespan in Drosophila. Aging 2: 200-223.
    • (2010) Aging , vol.2 , pp. 200-223
    • Sanz, A.1    Fernández-Ayala, D.J.2    Stefanatos, R.K.3    Jacobs, H.T.4
  • 29
    • 77952689461 scopus 로고    scopus 로고
    • Expression of the yeast NADH dehydrogenase Ndi1 in Drosophila confers increased lifespan independently of dietary restriction
    • Sanz, A., M. Soikkeli, M. Portero-Otín, A. Wilson, E. Kemppainen et al., 2010b Expression of the yeast NADH dehydrogenase Ndi1 in Drosophila confers increased lifespan independently of dietary restriction. Proc. Natl. Acad. Sci. USA 107: 9105-9110.
    • (2010) Proc. Natl. Acad. Sci. USA , vol.107 , pp. 9105-9110
    • Sanz, A.1    Soikkeli, M.2    Portero-Otín, M.3    Wilson, A.4    Kemppainen, E.5
  • 30
    • 79957960940 scopus 로고    scopus 로고
    • Metabolic control of mitochondrial biogenesis through the PGC-1 family regulatory network
    • Scarpulla, R. C., 2011 Metabolic control of mitochondrial biogenesis through the PGC-1 family regulatory network. Biochim. Biophys. Acta 1813: 1269-1278.
    • (2011) Biochim. Biophys. Acta , vol.1813 , pp. 1269-1278
    • Scarpulla, R.C.1
  • 31
    • 0028180084 scopus 로고
    • A mutation of the Drosophila sodium pump alpha subunit gene results in bang-sensitive paralysis
    • Schubiger, M., Y. Feng, D. M. Fambrough, and J. Palka, 1994 A mutation of the Drosophila sodium pump alpha subunit gene results in bang-sensitive paralysis. Neuron 12: 373-381.
    • (1994) Neuron , vol.12 , pp. 373-381
    • Schubiger, M.1    Feng, Y.2    Fambrough, D.M.3    Palka, J.4
  • 32
    • 0031578910 scopus 로고    scopus 로고
    • Metazoan nuclear genes for mitoribosomal protein S12
    • Shah, Z. H., K. M. C. O'Dell, S. C. Miller, X. An, and H. T. Jacobs, 1997 Metazoan nuclear genes for mitoribosomal protein S12. Gene 204: 55-62.
    • (1997) Gene , vol.204 , pp. 55-62
    • Shah, Z.H.1    O'Dell, K.M.C.2    Miller, S.C.3    An, X.4    Jacobs, H.T.5
  • 33
    • 0034809484 scopus 로고    scopus 로고
    • technical knockout, a Drosophila model of mitochondrial deafness
    • Toivonen, J. M., K. M. O'Dell, N. Petit, S. C. Irvine, G. K. Knight et al., 2001 technical knockout, a Drosophila model of mitochondrial deafness. Genetics 159: 241-254.
    • (2001) Genetics , vol.159 , pp. 241-254
    • Toivonen, J.M.1    O'Dell, K.M.2    Petit, N.3    Irvine, S.C.4    Knight, G.K.5
  • 34
    • 45149120493 scopus 로고    scopus 로고
    • Mutation of Drosophila focal adhesion kinase induces bang-sensitive behavior and disrupts glial function, axonal conduction and synaptic transmission
    • Ueda, A., C. Grabbe, J. Lee, J. Lee, R. H. Palmer et al., 2008 Mutation of Drosophila focal adhesion kinase induces bang-sensitive behavior and disrupts glial function, axonal conduction and synaptic transmission. Eur. J. Neurosci. 27: 2860-2870.
    • (2008) Eur. J. Neurosci. , vol.27 , pp. 2860-2870
    • Ueda, A.1    Grabbe, C.2    Lee, J.3    Lee, J.4    Palmer, R.H.5
  • 35
    • 84902259954 scopus 로고    scopus 로고
    • Phenotypic rescue of a Drosophila model of mitochondrial ANT1 disease
    • Vartiainen, S., S. Chen, J. George, T. Tuomela, K. R. Luoto et al., 2014 Phenotypic rescue of a Drosophila model of mitochondrial ANT1 disease. Dis. Model. Mech. 7: 635-648.
    • (2014) Dis. Model. Mech. , vol.7 , pp. 635-648
    • Vartiainen, S.1    Chen, S.2    George, J.3    Tuomela, T.4    Luoto, K.R.5
  • 36
    • 0036859943 scopus 로고    scopus 로고
    • The Drosophila slamdance gene: a mutation in an aminopeptidase can cause seizure, paralysis and neuronal failure
    • Zhang, H., J. Tan, E. Reynolds, D. Kuebler, S. Faulhaber et al., 2002 The Drosophila slamdance gene: a mutation in an aminopeptidase can cause seizure, paralysis and neuronal failure. Genetics 162: 1283-1299.
    • (2002) Genetics , vol.162 , pp. 1283-1299
    • Zhang, H.1    Tan, J.2    Reynolds, E.3    Kuebler, D.4    Faulhaber, S.5
  • 37
    • 0032843441 scopus 로고    scopus 로고
    • stress sensitive B encodes an Adenine Nucleotide Translocase in Drosophila melanogaster
    • Zhang, Y. Q., J. Roote, S. Brogna, A. W. Davis, D. A. Barbash et al., 1999 stress sensitive B encodes an Adenine Nucleotide Translocase in Drosophila melanogaster. Genetics 153: 891-903.
    • (1999) Genetics , vol.153 , pp. 891-903
    • Zhang, Y.Q.1    Roote, J.2    Brogna, S.3    Davis, A.W.4    Barbash, D.A.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.