Expression of alternative oxidase in Drosophila ameliorates diverse phenotypes due to cytochrome oxidase deficiency

Human Molecular Genetics

Volumn 23, Issue 8, 2014, Pages 2078-2093

  Kemppainen, Kia K ^a   Rinne, Juho ^a   Sriram, Ashwin ^a   Lakanmaa, Matti ^a   Zeb, Akbar ^a   Tuomela, Tea ^a   Popplestone, Anna ^a   Singh, Satpal ^b   Sanz, Alberto ^a   Rustin, Pierre ^c   Jacobs, Howard T ^a,d  

^a TAMPERE UNIVERSITY OF TECHNOLOGY   (Finland)

^b UNIVERSITY AT BUFFALO   (United States)

^c HÔPITAL ROBERT DEBRÉ   (France)

^d UNIVERSITY OF HELSINKI   (Finland)

Author keywords

[No Author keywords available]

Indexed keywords

ALTERNATIVE OXIDASE; CYTOCHROME C OXIDASE; MITOCHONDRIAL ENZYME; OXIDOREDUCTASE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE (UBIQUINONE); UNCLASSIFIED DRUG;

ADULT; ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; COVB GENE; CYTOCHROME C OXIDASE DEFICIENCY; DROSOPHILA; ENZYME ACTIVITY; ENZYME MECHANISM; ENZYME SUBUNIT; FEMALE; GENE SILENCING; LETHALITY; MALE; MITOCHONDRIAL GENE; MOTOR DYSFUNCTION; NERVE CELL; NONHUMAN; PAEDOGENESIS; PHENOTYPE; PRIORITY JOURNAL; PROTEIN ASSEMBLY; PROTEIN EXPRESSION; PROTEIN MULTIMERIZATION; RESPIRATORY CHAIN; SEIZURE;

ANIMALS; ANIMALS, GENETICALLY MODIFIED; BLOTTING, WESTERN; CELLS, CULTURED; CYTOCHROME-C OXIDASE DEFICIENCY; DEVELOPMENTAL DISABILITIES; DROSOPHILA MELANOGASTER; ELECTRON TRANSPORT COMPLEX IV; FEMALE; HUMANS; IMMUNOENZYME TECHNIQUES; INFERTILITY, MALE; MALE; MITOCHONDRIA; MITOCHONDRIAL PROTEINS; NEURODEGENERATIVE DISEASES; OXIDOREDUCTASES; PHENOTYPE; PLANT PROTEINS; REAL-TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER;

EID: 84897880940     PISSN: 09646906     EISSN: 14602083     Source Type: Journal    
DOI: 10.1093/hmg/ddt601     Document Type: Article

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