Evaluation of in vitro vs. in vivo methods for assessment of dermal absorption of organic flame retardants: A review

Environment International

Volumn 74, Issue , 2015, Pages 13-22

  Abdallah, Mohamed Abou Elwafa ^a,b   Pawar, Gopal ^a   Harrad, Stuart ^a  

^a UNIVERSITY OF BIRMINGHAM   (United Kingdom)

^b Assiut University   (Egypt)

Author keywords

Bioavailability; Dermal absorption; Flame retardants; Human exposure; Human skin equivalents

Indexed keywords

BIOCHEMISTRY; ORGANIC POLLUTANTS; RISK ASSESSMENT; RISK PERCEPTION;

BIOAVAILABILITY; BROMINATED FLAME RETARDANTS; DERMAL ABSORPTION; HUMAN EXPOSURES; HUMAN SKIN; PERCUTANEOUS PENETRATION; PERSISTENT ORGANIC POLLUTANT (POP); PHARMACOKINETIC STUDIES;

FLAME RETARDANTS;

FLAME RETARDANT; HEXABROMOCYCLODODECANE; PHOSPHORIC ACID TRIS(2 CHLOROETHYL) ESTER; POLYBROMINATED DIPHENYL ETHER; TRIS(1,3 DICHLORO 2 PROPYL)PHOSPHATE; TRIS(2 CHLORO 1 METHYLETHYL)PHOSPHATE; UNCLASSIFIED DRUG; XENOBIOTIC AGENT; ORGANIC COMPOUND; POLLUTANT;

ADSORPTION; BIOAVAILABILITY; CHEMICAL POLLUTANT; GUIDELINE; ORGANIC POLLUTANT; POLLUTION EXPOSURE; RISK ASSESSMENT; SKIN; THREE-DIMENSIONAL MODELING;

ENVIRONMENTAL EXPOSURE; HUMAN; HUMAN SKIN EQUIVALENT MODEL; IN VITRO STUDY; IN VIVO STUDY; INTERMETHOD COMPARISON; NONBIOLOGICAL MODEL; NONHUMAN; PERSISTENT ORGANIC POLLUTANT; REVIEW; RISK ASSESSMENT; SKIN ABSORPTION; SKIN PERMEABILITY; SKINFOLD THICKNESS; THREE DIMENSIONAL IMAGING; TOXICITY TESTING; XENOBIOTIC METABOLISM; ANIMAL; BIOAVAILABILITY; DERMIS; METABOLISM; PHARMACOKINETICS; POLLUTANT; TISSUE CULTURE TECHNIQUE;

ANIMALS; BIOLOGICAL AVAILABILITY; DERMIS; ENVIRONMENTAL EXPOSURE; ENVIRONMENTAL POLLUTANTS; FLAME RETARDANTS; HUMANS; ORGANIC CHEMICALS; RISK ASSESSMENT; SKIN ABSORPTION; TISSUE CULTURE TECHNIQUES; XENOBIOTICS;

EID: 84908426087     PISSN: 01604120     EISSN: 18736750     Source Type: Journal    
DOI: 10.1016/j.envint.2014.09.012     Document Type: Review

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