Gene expression profiles of three different models of reconstructed human epidermis and classical cultures of keratinocytes using cDNA arrays

Archives of Dermatological Research

Volumn 296, Issue 4, 2004, Pages 145-156

  Mehul B ^a   Asselineau, D ^a   Bernard, D ^a   Leclaire, J ^a   Regnier M ^a   Schmidt, R ^a   Bernerd, F ^a  

^a L ORÉAL RECHERCHE   (France)

Author keywords

cDNA arrays; Keratinocyte differentiation; Reconstructed epidermis

Indexed keywords

BULLOUS PEMPHIGOID ANTIGEN 1; CALMODULIN LIKE SKIN PROTEIN; CASPASE 14; COLECALCIFEROL RECEPTOR; COLLAGEN GEL; COLLAGENASE 3; CORNEODESMOSIN; CORNIFIN A; CORNIFIN B; DESMOCOLLIN; DESMOPLAKIN; FILAGGRIN; FLI 1 ONCOPROTEIN; GALECTIN; GALECTIN 7; GENE PRODUCT; GLYCEROPHOSPHOINOSITOL INOSITOLPHOSPHODIESTERASE; GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 153; KERATIN; KERATIN TYPE 1; LORICRIN; ONCOPROTEIN; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PLAKOGLOBIN; PLASTIC; PROCOLLAGEN; PROCOLLAGEN ALPHA 2; SMALL PROLINE RICH PROTEIN 2B; SMALL PROTEIN RICH PROTEIN 2-1; TRIACYLGLYCEROL LIPASE; UNCLASSIFIED DRUG;

ARTICLE; CELL DIFFERENTIATION; CELL PROLIFERATION; COMPARATIVE STUDY; CONTROLLED STUDY; DNA MICROARRAY; EPIDERMIS; FIBROBLAST; GENE EXPRESSION PROFILING; GENE OVEREXPRESSION; HISTOLOGY; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; KERATINOCYTE; PRIORITY JOURNAL; SKIN CULTURE;

EID: 5644261441     PISSN: 03403696     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00403-004-0491-2     Document Type: Article

References (83)

1. Applegate LA, Scaletta C, Panizzon R, Frenk E (1998) Evidence that ferritin is UV inducible in human skin: part of a putative defense mechanism. J Invest Dermatol 111:159-163
2. Arnemann J, Sullivan KH, Magee AI, King IA, Buxton RS (1993) Stratification-related expression of isoforms of the desmosomal cadherins in human epidermis. J Cell Sci 104:741-750
3. Asselineau D, Bernard BA, Bailly C, Darmon M (1985) Epidermal morphogenesis and induction of the 67 kD keratin polypeptide by culture at the liquid-air interface. Exp Cell Res 159:536-539
4. Asselineau D, Bernard BA, Bailly C, Darmon M (1989) Retinoic acid improves epidermal morphogenesis. Dev Biol 133:322-335
5. Banks-Schlegel S, Green H (1981) Involucrin synthesis and tissue assembly by keratinocytes in natural and cultured human epithelia. J Cell Biol 90:732-737
6. Barondes SH, Cooper DN, Gitt MA, Leffler H (1994) Galectins. Structure and function of a large family of animal lectins. J Biol Chem 269:20807-20810
7. Bastian BC, van der Piepen U, Romisch J, Paques EP, Brocker EB (1993) Localization of annexins in normal and diseased human skin. J Dermatol Sci 6:225-234
8. Beißbarth T, Fellenberg K, Brors B, Arribas-Prat R, Boer J, Hauser NC, Scheideler M, Hoheisel JD, Schutz G, Poustka A, Vingron M (2000) Processing and quality control of DNA array hybridization data. Bioinformatics 16:1014-1022
9. Bell E, Ivarsson B, Merrill C (1979) Production of a tissue-like structure by contraction of collagen lattices by human fibroblasts of different proliferative potential in vitro. Proc Natl Acad Sci U S A 76:1274-1278
10. Bernard FX, Pedretti N, Rosdy M, Deguercy A (2002) Comparison of gene expression profiles in human keratinocyte mono-layer cultures, reconstituted epidermis and normal human skin; transcriptional effects of retinoid treatments in reconstituted human epidermis. Exp Dermatol 11:59-74
11. Bernerd F, Asselineau D (1997) Successive alteration and recovery of epidermal differentiation and morphogenesis after specific UVB-damages in skin reconstructed in vitro. Dev Biol 183:123-138
12. Bernerd F, Asselineau D (1998) UV A exposure of human skin reconstructed in vitro induces apoptosis of dermal fibroblasts: subsequent connective tissue repair and implications in photoaging. Cell Death Differ 5:792-802
13. Bernerd F, Magnaldo T, Darmon M (1992) Delayed onset of epidermal differentiation in psoriasis. J Invest Dermatol 98:902-910
14. Bernstam LI, Vaughan FL, Berstein IA (1988) Keratinocytes grown at the air-liquid interface. In vitro Cell Dev Biol 22:695-705
15. Boelsma E, Gibbs S, Faller C, Ponec M (2000) Characterization and comparison of reconstructed skin models: morphological and immunohistochemical evaluation. Acta Derm Venereol 80:82-88
16. Bornslaeger EA, Godsel LM, Corcoran CM, Park JK, Hatzfeld M, Kowalczyk AP, Green KJ (2001) Plakophilin 1 interferes with plakoglobin binding to desmoplakin, yet together with plakoglobin promotes clustering of desmosomal plaque complexes at cell-cell borders. J Cell Sci 114:727-738
17. Bouwstra JA, Gooris GS, Weerheim A, Kempenaar J, Ponec M (1995) Characterization of stratum corneum structure in reconstructed epidermis by X-ray diffraction. J Lipid Res 36:496-504
18. Boyce ST, Christianson DJ, Hansbrough JF (1988) Structure of a collagen-GAG dermal skin substitute optimized for cultured human epidermal keratinocytes. J Biomed Mater Res 22:939-957
19. Byrne C, Tainsky M, Fuchs E (1994) Programming gene expression in developing epidermis. Development 120:2369-2383
20. Chidgey MA, Yue KK, Gould S, Byrne C, Garrod DR (1997) Changing pattern of desmocollin 3 expression accompanies epidermal organisation during skin development. Dev Dyn 210:315-327
21. Cohen C, Roguet R, Cottin M, Olive C, Leclaire J, Rougier A (1998) The use of a reconstructed epidermis in the evaluation of protective effect of sunscreens against chemical phototoxicity induced by UV. In: Rougier A.-A., Schaefer H (eds) John Libbey, Paris, pp 195-200
22. Contard P, Bartel R, Jacob L II, Perlish JS, MacDonald ED II, Handler L, Cone D, Fleischmajer R (1993) Culturing keratinocytes and fibroblasts in a three dimensional mesh results in epidermal differentiation and formation of a basal lamina anchoring zone. J Invest Dermatol 100:35-39
23. Curto EV, Lambert GW, Davis RL, Wilborn TW, Dooley TP (2002) Biomarkers of human skin cells identified using Derm-Array DNA arrays and new bioinformatics methods. Biochem Biophys Res Commun 291:1052-1064
24. Denning MF, Guy SG, Ellerbroek SM, Norvell SM, Kowalczyk AP, Green KJ (1998) The expression of desmoglein isoforms in cultured human keratinocytes is regulated by calcium, serum, and protein kinase C. Exp Cell Res 239:50-59
25. Eckert RL, Yaffe MB, Crish JF, Murthy S, Rorke EA, Welter JF (1993) Involucrin-structure and role in envelope assembly. J Invest Dermatol 100:613-617
26. Eckert RL, Crish JF, Banks EB, Welter JF (1997) The epidermis: genes on-genes off. J Invest Dermatol 109:501-509
27. Eckhart L, Ban J, Fischer H, Tschachler E (2000) Caspase-14: analysis of gene structure and mRNA expression during keratinocyte differentiation. Biochem Biophys Res Commun 277:655-659
28. Ekholm E, Egelrud T (2000) Expression of stratum corneum chymotryptic enzyme in relation to other markers of epidermal differentiation in a skin explant model. Exp Dermatol 9:65-70
29. Enerback C, Porter DA, Seth P, Sgroi D, Gaudet J, Weremowicz S, Morton CC, Schnitt S, Pitts RL, Stampl J, Barnhart K, Polyak K (2002) Psoriasin expression in mammary epithelial cells in vitro and in vivo. Cancer Res 62:43-47
30. Fleckman P, Dale BA, Holbrook KA (1985) Profilaggrin, a high-molecular-weight precursor of filaggrin in human epidermis and cultured keratinocytes. J Invest Dermatol 85:507-512
31. Fuchs E (1993) Epidermal differentiation and keratin gene expression. J Cell Sci [Suppl 17]:197-208
32. Fuchs E, Byrne C (1994) The epidermis: rising to the surface. Curr Opin Genet Dev 4:725-736
33. Fuchs E, Green H (1980) Changes in keratin gene expression during terminal differentiation of the keratinocyte. Cell 19:1033-1042
34. Fujimoto W, Nakanishi G, Arata J, Jetten AM (1997) Differential expression of human cornifin alpha and beta in squamous differentiating epithelial tissues and several skin lesions. J Invest Dermatol 108:200-204
35. Gazel A, Ramphal P, Rosdy M, De Wever B, Tornier C, Hosein N, Lee B, Tomic-Canic M, Blumenberg M (2003) Transcriptional profiling of epidermal keratinocytes: comparison of genes expressed in skin, cultured keratinocytes, and reconstructed epidermis, using large scale DNA microarrays. J Invest Dermatol 121:1459-1468
36. Gibson DF, Ratnam AV, Bikle DD (1996) Evidence for separate control mechanisms at the message, protein, and enzyme activation levels for transglutaminase during calcium-induced differentiation of normal and transformed human keratinocytes. J Invest Dermatol 106:154-161
37. Hansson L, Stromqvist M, Backman A, Wallbrandt P, Carlstein A, Egelrud T (1994) Cloning, expression, and characterization of stratum corneum chymotryptic enzyme. A skin-specific human serine proteinase. J Biol Chem 269:19420-19426
38. Jiang CK, Magnaldo T, Ohtsuki M, Freedberg IM, Bernerd F, Blumenberg M (1993) Epidermal growth factor and transforming growth factor α specifically induce the activation- and hyperproliferation-associated keratins 6 and 16. Proc Natl Acad Sci U S A 90:6786-6790
39. Kartasova T, van de Putte P (1988) Isolation, characterization, and UV-stimulated expression of two families of genes encoding polypeptides of related structure in human epidermal keratinocytes. Mol Cell Biol 8:2195-2203
40. Kivirikko S, McGrath JA, Baudoin C, Aberdam D, Ciatti S, Dunnill MG, McMillan JR, Eady RA, Ortonne JP, Meneguzzi G, et al (1995) A homozygous nonsense mutation in the alpha 3 chain gene of laminin 5 (LAMA3) in lethal (Herlitz) junctional epidermolysis bullosa. Hum Mol Genet 4:959-962
41. Kuechle MK, Predd HM, Fleckman P, Dale BA, Presland RB (2001) Caspase-14, a keratinocyte specific caspase: mRNA splice variants and expression pattern in embryonic and adult mouse. Cell Death Differ 8:868-870
42. Lillie JH, MacCallum DK, Jepsen A (1980) Fine structure of subcultivated stratified squamous epithelium grown on collagen rafts. Exp Cell Res 125:153-165
43. Magnaldo T, Barrandon Y (1996) CD24 (heat stable antigen, nectadrin), a novel keratinocyte differentiation marker, is preferentially expressed in areas of the hair follicle containing the colony-forming cells. J Cell Sci 109:3035-3045
44. Magnaldo T, Bernerd F, Asselineau D, Darmon M (1992) Expression of loricrin is negatively controlled by retinoic acid in human epidermis reconstructed in vitro. Differentiation 49:39-46
45. Magnaldo T, Bernerd F, Darmon M (1995) Galectin-7, a human 14-kDa S-lectin, specifically expressed in keratinocytes and sensitive to retinoic acid. Dev Biol 168:259-271
46. Marinkovich MP, Verrando P, Keene DR, Meneguzzi G, Lunstrum GP, Ortonne JP, Burgeson RE (1993) Basement membrane proteins kalinin and nicein are structurally and immunologically identical. Lab Invest 69:295-299
47. Marionnet C, Bernerd F, Dumas A, Verrecchia F, Mollier K, Compan D, Bernard B, Lahfa M, Leclaire J, Medaisko C, Méhul B, Seite S, Mauviel A, Dubertret L (2003) Modulation of gene expression induced in human epidermis by environmental stress in vivo. J Invest Dermatol 121:1447-1458
48. Méhul B, Bernard D, Simonetti L, Bernard MA, Schmidt R (2000) Identification and cloning of a new calmodulin-like protein from human epidermis. J Biol Chem 275:12841-12847
49. Méhul B, Bernard D, Schmidt R (2001) Calmodulin-like skin protein: a new marker of keratinocyte differentiation. J Invest Dermatol 116:905-909
50. Michel S, Bernerd F, Jetten AM, Floyd EE, Shroot B, Reichert U (1992) Expression of keratinocyte transglutaminase mRNA revealed by in situ hybridization. J Invest Dermatol 98:364-368
51. Munz B, Gerke V, Gillitzer R, Werner S (1997) Differential expression of the calpactin I subunits annexin II and pII in cultured keratinocytes and during wound repair. J Invest Dermatol 108:307-312
52. Naughton GK, Jacob L, Naughton BA (1989) A physiological skin model for in vitro toxicity studies. In: Goldberg AM (ed) Alternative methods in toxicology, vol 7. Mary Ann Liebert, New York, pp 183-189
53. North AJ, Bardsley WG, Hyam J, Bornslaeger EA, Cordingley HC, Trinnaman B, Hatzfeld M, Green KJ, Magee AI, Garrod DR (1999) Molecular map of the desmosomal plaque. J Cell Sci 112:4325-4336
54. Pechkovsky DV, Zalutskaya OM, Ivanov GI, Misuno NI (2000) Calprotectin (MRP8/14 protein complex) release during mycobacterial infection in vitro and in vivo. FEMS Immunol Med Microbiol 29:27-33
55. Ponec M (1991) Reconstruction of human epidermis on deepidermized dermis: expression of differentiation-specific protein markers and lipid composition. Toxicol In Vitro 5:597-606
56. Prunieras M, Régnier M, Schlotterer M (1979) Nouveau procédé de culture des cellules épidermiques humaines sur derme homologue ou hétérologue: préparation de greffons recombinés. Ann Chir Plast 24:357-362
57. Prunieras M, Régnier M, Woodley DT (1983) Methods for cultivation of keratinocytes with an air-liquid interface. J Invest Dermatol 81:285-335
58. Reddy SP, Konkin T, Wu R (1998) Structure and organization of the genes encoding mouse small proline-rich proteins, mSPRR1A and 1B. Gene 224:59-66
59. Régnier M, Darmon M (1989) Human epidermis reconstructed in vitro: a model to study keratinocyte differentiation and its modulation by retinoic acid. In Vitro Cell Dev Biol 25:1000-1008
60. Regnier M, Darmon M (1991) 1,25-Dihydroxyvitamin D3 stimulates specifically the last steps of epidermal differentiation of cultured human keratinocytes. Differentiation 47:173-188
61. Regnier M, Prunieras M, Woodley D (1981) Growth and differentiation of adult human epidermal cells on dermal substrates. Front Matrix Biol 9:4-35
62. Régnier M, Schweizer J, Michel S, Bailly C, Prunieras M (1986) Expression of high molecular weight (67 kD) keratin in isolated human keratinocytes cultured on dead de-epidermized dermis. Exp Cell Res 165:63-72
63. Régnier M, Asselineau D, Lenoir MC (1990) Human epidermis reconstructed on dermal substrates in vitro: an alternative to animals in skin pharmacology. Skin Pharmacol 3:70-85
64. Régnier M, Duval C, Schmidt R (1999) Potential cosmetic applications of reconstructed epidermis. Int J Cosmet Sci 21:51-58
65. Rendl M, Ban J, Mrass P, Mayer C, Lengauer B, Eckhart L, Declerq W, Tschachler E (2002) Caspase-14 expression by epidermal keratinocytes is regulated by retinoids in a differentiation-associated manner. J Invest Dermatol 119:1150-1155
66. Rentrop M, Knapp B, Winter H, Schweizer J (1986) Differential localization of distinct keratin mRNA-species in mouse tongue epithelium by in situ hybridization with specific cDNA probes. J Cell Biol 103:2583-2591
67. Rheinwald JG, Green H (1975) Serial cultivation of strains of human keratinocytes: the formation of keratinizing colonies from single cells. Cell 6:331-343
68. Rice RH, Qin Q, Pilato A, Rubin AL (1992) Keratinocyte differentiation markers: involucrin, transglutaminase, and toxicity. J Natl Cancer Inst Monogr 13:87-91
69. Roguet R, Cohen C, Robles C, Courtellemont P, Tolle M, Guillot JP, Pouradier, Duteil X (1998) An interlaboratory study of the reproducibility and relevance of Episkin, a reconstructed human epidermis, in the assessment of cosmetics irritancy. Toxicol In Vitro 12:295-304
70. Rosdy M, Clauss LC (1990) Terminal epidermal differentiation of human keratinocytes grown in chemically defined medium on inert filter substrates at the air-liquid interface. J Invest Dermatol 95:409-414
71. Rothnagel JA, Greenhalgh DA, Gagne TA, Longley MA, Roop DR (1993) Identification of a calcium-inducible, epidermal-specific regulatory element in the 3′-flanking region of the human keratin I gene. J Invest Dermatol 101:506-513
72. Saintigny G, Schmidt R, Shroot B, Juhlin L, Reichert U, Michel S (1992) Differential expression of calgranulin A and B in various epithelial cell lines and reconstructed epidermis. J Invest Dermatol 99:639-644
73. Schermer A, Jester JV, Hardy C, Milano D, Sun TT (1989) Transient synthesis of K6 and K16 keratins in regenerating rabbit corneal epithelium: keratin markers for an alternative pathway of keratinocyte differentiation. Differentiation 42:103-110
74. Schweizer J, Kinjo M, Fürstenberger G, Winter H (1984) Sequential expression of mRNA-encoded keratin sets in neonatal mouse epidermis: basal cells with properties of terminally differentiating cells. Cell 37:159-170
75. Serre G, Mils V, Haftek M, Vincent C, Croute F, Reano A, Ouhayoun JP, Bettinger S, Soleilhavoup JP (1991) Identification of late differentiation antigens of human cornified epithelia, expressed in re-organized desmosomes and bound to crosslinked envelope. J Invest Dermatol 97:1061-1072
76. Siegenthaler G, Roulin K, Chatellard-Gruaz D, Hotz R, Saurat JH, Hellman U, Hagens G (1997) A heterocomplex formed by the calcium-binding proteins MRP8 (S100A8) and MRP14 (S100A9) binds unsaturated fatty acids with high affinity. J Biol Chem 272:9371-9377
77. Simon M, Jonca N, Guerrin M, Haftek M, Bernard D, Caubet C, Egelrud T, Schmidt R, Serre G (2001) Refined characterization of corneodesmosin proteolysis during terminal differentiation of human epidermis and its relationship to desquamation. J Biol Chem 276:20292-20299
78. Stanley JR, Hawley-Nelson P, Yaar M, Martin GR, Katz SI (1982) Laminin and bullous pemphigoid antigen are distinct basement membrane proteins synthesized by epidermal cells. J Invest Dermatol 78:456-459
79. Tinois E, Tiollier J, Gaucherand M, Dumas H, Tardy M, Thivolet J (1991) In vitro and post-transplantation differentiation of human keratinocytes grown on the human type IV collagen film of a bilayered dermal substitute. Exp Cell Res 193:310-319
80. Törma H, Asselineau D, Anderson E, Martin B, Shroot B, Darmon M, Vahlquist A (1994) Biological activities of RA and 3,4 ddRA in human keratinocytes are similar and correlate with receptor affinities and transactivation properties. J Invest Dermatol 102:49-54
81. Watson PH, Leygue ER, Murphy LC (1998) Psoriasin (S100A7). Int J Biochem Cell Biol 30:567-571
82. Watt FM (1983) Involucrin and other markers of keratinocyte terminal differentiation. J Invest Dermatol 81:100s-103s
83. Watt FM, Green H (1981) Involucrin synthesis is correlated with cell size in human epidermal cultures. J Cell Biol 90:738-742