Metabolically competent human skin models: Activation and genotoxicity of benzo[a]pyrene

Toxicological Sciences

Volumn 131, Issue 2, 2013, Pages 351-359

  Brinkmann, Joep ^a   Stolpmann, Kristin ^a   Trappe, Susanne ^a   Otter, Timo ^a   Genkinger, Doris ^a   Bock, Udo ^b   Liebsch, Manfred ^a   Henkler, Frank ^a   Hutzler, Christoph ^a   Luch, Andreas ^a  

^a FEDERAL INSTITUTE FOR RISK ASSESSMENT   (Germany)

^b ACROSS BARRIERS GMBH   (Germany)

Author keywords

Benzo a pyrene; Comet assay; Human skin; Metabolism; Primary normal human epidermal keratinocytes; Skin models

Indexed keywords

BENZO[A]PYRENE;

ARTICLE; CATALYSIS; COMET ASSAY; CONTROLLED STUDY; EX VIVO STUDY; FOLLOW UP; GENOTOXICITY; HUMAN; HUMAN TISSUE; KERATINOCYTE; LIQUID CHROMATOGRAPHY; METABOLIC ACTIVATION; SKIN; SKIN CULTURE; TANDEM MASS SPECTROMETRY;

BENZO(A)PYRENE; BIOTRANSFORMATION; CELLS, CULTURED; CHROMATOGRAPHY, LIQUID; HUMANS; MODELS, BIOLOGICAL; MUTAGENICITY TESTS; MUTAGENS; SKIN; TANDEM MASS SPECTROMETRY;

EID: 84873820397     PISSN: 10966080     EISSN: 10960929     Source Type: Journal    
DOI: 10.1093/toxsci/kfs316     Document Type: Article

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