Antimycobacterial activity of natural products and synthetic agents: Pyrrolodiquinolines and vermelhotin as anti-tubercular leads against clinical multidrug resistant isolates of Mycobacterium tuberculosis

European Journal of Medicinal Chemistry

Volumn 89, Issue , 2015, Pages 1-12

  Ganihigama, Dakshina U ^a   Sureram, Sanya ^b   Sangher, Sasithorn ^b   Hongmanee, Poonpilas ^c   Aree, Thammarat ^d   Mahidol, Chulabhorn ^a,b   Ruchirawat, Somsak ^a,b,e   Kittakoop, Prasat ^a,b,e  

^a Research and Innovation   (Thailand)

^b CHULABHORN RESEARCH INSTITUTE   (Thailand)

^c MAHIDOL UNIVERSITY   (Thailand)

^d CHULALONGKORN UNIVERSITY   (Thailand)

^e Thailand Ministry of Science and Technology   (Thailand)

Author keywords

Antimycobacterial activity; Antimycobacterial compound; Microwave assisted synthesis; Multidrug resistant tuberculosis; Mycobacterium tuberculosis; Natural product

Indexed keywords

1 METHYLQUINOLINIUM IODIDE; ANTIMYCOBACTERIAL AGENT; BENZOXAZOCINE DERIVATIVE; COUMARIN; COUMARIN DERIVATIVE; ETHAMBUTOL; IODIDE; ISONIAZID; NATURAL PRODUCT; OFLOXACIN; PYRROLODIQUINOLINE DERIVATIVE; RIFAMPICIN; STREPTOMYCIN; TUBERCULOSTATIC AGENT; UNCLASSIFIED DRUG; VERMELHOTIN; BIOLOGICAL PRODUCT; PYRROLIDINE DERIVATIVE; QUINOLINE DERIVATIVE;

ARTICLE; CYTOTOXICITY; GREEN CHEMISTRY; MICROWAVE IRRADIATION; MINIMUM INHIBITORY CONCENTRATION; MULTIDRUG RESISTANT TUBERCULOSIS; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; ONE POT SYNTHESIS; X RAY CRYSTALLOGRAPHY; CHEMICAL STRUCTURE; CHEMISTRY; DOSE RESPONSE; DRUG EFFECTS; ISOLATION AND PURIFICATION; MICROBIAL SENSITIVITY TEST; MULTIDRUG RESISTANCE; STRUCTURE ACTIVITY RELATION; SYNTHESIS;

ANTITUBERCULAR AGENTS; BIOLOGICAL PRODUCTS; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG RESISTANCE, MULTIPLE, BACTERIAL; MICROBIAL SENSITIVITY TESTS; MOLECULAR STRUCTURE; MYCOBACTERIUM TUBERCULOSIS; PYRROLIDINES; QUINOLINES; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84908405187     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2014.10.026     Document Type: Article

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