Gene expression in the skin of dogs sensitized to the house dust mite Dermatophagoides farinae

G3: Genes, Genomes, Genetics

Volumn 4, Issue 10, 2014, Pages 1787-1795

  Schamber, Paz ^a,c   Schwab Richards, Rachel ^b   Bauersachs, Stefan ^a,d   Mueller, Ralf S ^c  

^a UNIVERSITY OF MUNICH   (Germany)

^b Novartis Centre de Recherche   (Switzerland)

^c Laboratory for Functional Genome Analysis Ludwig Maximilians Universität München ^*  (Germany)

^d ETH ZURICH   (Switzerland)

Author keywords

Allergy; Beagle; Canine; Canis familiaris; Microarray

Indexed keywords

ANTIGEN; MESSENGER RNA; TRANSCRIPTOME; ALLERGEN; HOUSE DUST ALLERGEN;

ANIMAL TISSUE; ARTICLE; ATOPIC DERMATITIS; BEAGLE; CONTROLLED STUDY; DERMATOPHAGOIDES FARINAE; DNA MICROARRAY; ENVIRONMENTAL FACTOR; FEMALE; GENE EXPRESSION; GENETIC PREDISPOSITION; IMMUNE RESPONSE; IMMUNOSTIMULATION; INFLAMMATION; MALE; NONHUMAN; NUCLEOTIDE SEQUENCE; PATCH TEST; PATHOGENESIS; PATHOPHYSIOLOGY; QUANTITATIVE ANALYSIS; REAL TIME POLYMERASE CHAIN REACTION; SKIN BIOPSY; WOUND HEALING; ANIMAL; BIOLOGY; DOG; DOWN REGULATION; DRUG EFFECTS; METABOLISM; PATHOLOGY; SKIN; TIME; UPREGULATION;

CANIS FAMILIARIS; DERMATOPHAGOIDES FARINAE; PYROGLYPHIDAE;

ALLERGENS; ANIMALS; ANTIGENS, DERMATOPHAGOIDES; COMPUTATIONAL BIOLOGY; DERMATITIS, ATOPIC; DERMATOPHAGOIDES FARINAE; DOGS; DOWN-REGULATION; FEMALE; MALE; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; REAL-TIME POLYMERASE CHAIN REACTION; RNA, MESSENGER; SKIN; TIME FACTORS; UP-REGULATION;

EID: 84908398946     PISSN: None     EISSN: 21601836     Source Type: Journal    
DOI: 10.1534/g3.114.013003     Document Type: Article

References (60)

1. Ando-Akatsuka, Y., M. Saitou, T. Hirase, M. Kishi, A. Sakakibara et al., 1996 Interspecies diversity of the occludin sequence: cDNA cloning of human, mouse, dog, and rat-kangaroo homologues. J. Cell Biol. 133: 43-47.
2. Barnes, K. C., 2010 An update on the genetics of atopic dermatitis: scratching the surface in 2009. J. Allergy Clin. Immunol. 125: 16-29.
3. Boguniewicz, M., and D. Y. Leung, 2011 Atopic dermatitis: a disease of altered skin barrier and immune dysregulation. Immunol. Rev. 242: 233-246.
4. Broccardo, C. J., S. Mahaffey, J. Schwarz, L. Wruck, G. David et al., 2011 Comparative proteomic profiling of patients with atopic dermatitis based on history of eczema herpeticum infection and Staphylococcus aureus colonization. J. Allergy Clin. Immunol. 127: 186-193.
5. Bussmann, C., S.Weidinger, and N. Novak, 2011 Genetics of atopic dermatitis. J. Dtsch. Dermatol. Ges. 9: 670-676.
6. Chapman, S. J., and A. Walsh, 1990 Desmosomes, corneosomes and desquamation. An ultrastructural study of adult pig epidermis. Arch. Dermatol. Res. 282: 304-310.
7. Cookson, W. O., and M. F. Moffatt, 2002 The genetics of atopic dermatitis. Curr. Opin. Allergy Clin. Immunol. 2: 383-387.
8. Credille, K. M., J. S. Minor, K. F. Barnhart, E. Lee, M. L. Cox et al., 2009 Transglutaminase 1-deficient recessive lamellar ichthyosis associated with a LINE-1 insertion in Jack Russell terrier dogs. Br. J. Dermatol. 161: 265-272.
9. DeBoer, D. J., and A. Hillier, 2001 The ACVD task force on canine atopic dermatitis (XV): fundamental concepts in clinical diagnosis. Vet. Immunol. Immunopathol. 81: 271-276.
10. DeBoer, D. J., and R. Marsella, 2001 The ACVD task force on canine atopic dermatitis (XII): the relationship of cutaneous infections to the pathogenesis and clinical course of canine atopic dermatitis. Vet. Immunol. Immunopathol. 81: 239-249.
11. Denecker, G., P. Ovaere, P. Vandenabeele, andW. Declercq, 2008 Caspase-14 reveals its secrets. J. Cell Biol. 180: 451-458.
12. Elias, P. M., 2005 Stratum corneum defensive functions: an integrated view. J. Invest. Dermatol. 125: 183-200.
13. Elias, P. M., and K. R. Feingold, 2001 Does the tail wag the dog? Role of the barrier in the pathogenesis of inflammatory dermatoses and therapeutic implications. Arch. Dermatol. 137: 1079-1081.
14. Elias, P.M., and M. Schmuth, 2009 Abnormal skin barrier in the etiopathogenesis of atopic dermatitis. Curr. Allergy Asthma Rep. 9: 265-272.
15. Frijters, R., B. Heupers, P. van Beek, M. Bouwhuis, R. van Schaik et al., 2008 CoPub: a literature-based keyword enrichment tool for microarray data analysis. Nucleic Acids Res. 36: W406-410.
16. Giustizieri, M. L., F. Mascia, A. Frezzolini, O. De Pita, L. M. Chinni et al., 2001 Keratinocytes from patients with atopic dermatitis and psoriasis show a distinct chemokine production profile in response to T cellderived cytokines. J. Allergy Clin. Immunol. 107: 871-877.
17. Halliwell, R., 2006 Revised nomenclature for veterinary allergy. Vet. Immunol. Immunopathol. 114: 207-208.
18. Hansson, L., A. Backman, A. Ny, M. Edlund, E. Ekholmet al., 2002 Epidermal overexpression of stratum corneum chymotryptic enzyme in mice: a model for chronic itchy dermatitis. J. Invest. Dermatol. 118: 444-449.
19. Hightower, K., R. Marsella, E. Creary, and P. Dutcher, 2008 Evaluation of transepidermal water loss in canine atopic dermatitis: a pilot study in Beagle dogs sensitized to house dust mites. Vet. Dermatol. 19: 108.
20. Hillier, A., and C. E. Griffin, 2001 The ACVD task force on canine atopic dermatitis (I): incidence and prevalence. Vet. Immunol. Immunopathol. 81: 147-151.
21. Horikoshi, T., S. Igarashi, H. Uchiwa, H. Brysk, and M. M. Brysk, 1999 Role of endogenous cathepsin D-like and chymotrypsin-like proteolysis in human epidermal desquamation. Br. J. Dermatol. 141: 453-459.
22. Huang, D. W., B. T. Sherman, and R. A. Lempicki, 2008 Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources. Nat. Protoc. 4: 44-57.
23. Huber, W., A. von Heydebreck, H. Sultmann, A. Poustka, and M. Vingron, 2002 Variance stabilization applied to microarray data calibration and to the quantification of differential expression. Bioinformatics 18(Suppl 1): S96-S104.
24. Inman, A. O., T. Olivry, S. M. Dunston, N. A. Monteiro-Riviere, and H. Gatto, 2001 Electron microscopic observations of stratum corneum intercellular lipids in normal and atopic dogs. Vet. Pathol. 38: 720-723.
25. Kaburagi, Y., Y. Shimada, T. Nagaoka, M. Hasegawa, K. Takehara et al., 2001 Enhanced production of CC-chemokines (RANTES, MCP-1, MIP-1alpha, MIP-1beta, and eotaxin) in patients with atopic dermatitis. Arch. Dermatol. Res. 293: 350-355.
26. Kanehisa, M., M. Araki, S. Goto, M. Hattori, M. Hirakawa et al., 2008 KEGG for linking genomes to life and the environment. Nucleic Acids Res. 36: D480-D484.
27. Leung, D. Y., 1999 Pathogenesis of atopic dermatitis. J. Allergy Clin. Immunol. 104: S99-S108.
28. Leyden, J. J., R. R. Marples, and A. M. Kligman, 1974 Staphylococcus aureus in the lesions of atopic dermatitis. Br. J. Dermatol. 90: 525-530.
29. Lian, T. M., and R. E. W. Halliwell, 1998 Allergen-specific IgE and IgGd antibodies in atopic and normal dogs. Vet. Immunol. Immunopathol. 66: 203-223.
30. Lindblad-Toh, K., C. M. Wade, T. S. Mikkelsen, E. K. Karlsson, D. B. Jaffe et al., 2005 Genome sequence, comparative analysis and haplotype structure of the domestic dog. Nature 438: 803-819.
31. Marenholz, I., V. A. Rivera, J. Esparza-Gordillo, A. Bauerfeind,M. A. Lee-Kirsch et al., 2011 Association screening in the Epidermal Differentiation Complex (EDC) identifies an SPRR3 repeat number variant as a risk factor for eczema. J. Invest. Dermatol. 131: 1644-1649.
32. Marsella, R., T. Olivry, and S. Maeda, 2006 Cellular and cytokine kinetics after epicutaneous allergen challenge (atopy patch testing) with house dust mites in high-IgE beagles. Vet. Dermatol. 17: 111-120.
33. Marsella, R., D. Samuelson, K. Doerr, K. Hightower, and L. Harrington, 2008 Defective barrier function in an experimental model of atopic dermatitis in high IgE producing beagles. Proceedings of the 5th George Rajka International Symposium on Atopic Dermatitis, Kyoto: 18.
34. Marsella, R., T. Olivry, and D. N. Carlotti International Task Force on Canine Atopic Dermatitis, 2011 Current evidence of skin barrier dysfunction in human and canine atopic dermatitis. Vet. Dermatol. 22: 239-248.
35. Matsui, T., K. Miyamoto, A. Kubo, and H. Kawasaki, T. Ebihara T, et al., 2011 SASPase regulates stratum corneum hydration through profilaggrin-to-filaggrin processing. EMBO Mol. Med. 3: 320-333.
36. Merryman-Simpson, A. E., S. H. Wood, N. Fretwell, P. G. Jones, W. M. McLaren et al., 2008 Gene (mRNA) expression in canine atopic dermatitis: microarray analysis. Vet. Dermatol. 19: 59-66.
37. Minegishi, Y., and M. Saito, 2011 Molecular mechanisms of the immunological abnormalities in hyper-IgE syndrome. Ann. N. Y. Acad. Sci. 1246: 34-40.
38. Nishio, Y., E. Noguchi, M. Shibasaki, M. Kamioka, E. Ichikawa et al., 2003 Association between polymorphisms in the SPINK5 gene and atopic dermatitis in the Japanese. Genes Immun. 4: 515-517.
39. Nuttall, T. J., P. A. Knight, S. M. McAleese, J. R. Lamb, and P. B. Hill, 2002 Expression of Th1, Th2 and immunosuppressive cytokine gene transcripts in canine atopic dermatitis. Clin. Exp. Allergy 32: 789-795.
40. Oh, D. Y., R. R. Schumann, L. Hamann, K. Neumann, M. Worm et al., 2009 Association of the toll-like receptor 2 A-16934T promoter polymorphism with severe atopic dermatitis. Allergy 64: 1608-1615.
41. Olivry, T., D. J. DeBoer, C. E. Griffin, R. E. W. Halliwell, P. B. Hill et al., 2001 The ACVD task force on canine atopic dermatitis: forewords and lexicon. Vet. Immunol. Immunopathol. 81: 143-146.
42. Olivry, T., and C. A. Sousa, 2001 The ACVD task force on canine atopic dermatitis (XIX): general principles of therapy. Vet. Immunol. Immunopathol. 81: 311-316.
43. Olivry, T., A. P. Foster, R. S. Mueller, N. A. McEwan, C. Chesney et al., 2010 Interventions for atopic dermatitis in dogs: a systematic review of randomized controlled trials. Vet. Dermatol. 21: 4-22.
44. Palmer, C. N., A. D. Irvine, A. Terron-Kwiatkowski, Y. Zhao et al., 2006 Common loss-of-function variants of the epidermal barrier protein filaggrin are a major predisposing factor for atopic dermatitis. Nat. Genet. 38: 441-446.
45. Prefontaine, D., S. Lajoie-Kadoch, S. Foley, S. Audusseau, R. Olivenstein et al., 2009 Increased expression of IL-33 in severe asthma: evidence of expression by airway smooth muscle cells. J. Immunol. 183: 5094-5103.
46. Saeed, A. I., V. Sharov, J. White, J. Li, W. Liang et al., 2003 TM4: a free, open-source system for microarray data management and analysis. Biotechniques 34: 374-378.
47. Schulze, A., and J. Downward, 2001 Navigating gene expression using microarrays - a technology review. Nat. Cell Biol. 3: E190-E195.
48. Smyth, G. K., 2005 Limma: linear models for microarray data, pp. 397-420 in Bioinformatics and Computational Biology Solutions using R and Bioconductor, edited by R. Gentleman, S.Dudoit, R. Irizarry, and W.Huber, Springer, New York.
49. Streyl, D., R. Kenngott, N. Herbach, R. Wanke et al., 2012 Gene expression profiling of bovine peripartal placentomes: detection of molecular pathways potentially involved in the release of foetal membranes. Reproduction 143: 85-105.
50. Taha, R. A., E. M. Minshall, D. Y. Leung, M. Boguniewicz, A. Luster et al., 2000 Evidence for increased expression of eotaxin and monocyte chemotactic protein-4 in atopic dermatitis. J. Allergy Clin. Immunol. 105: 1002-1007.
51. Taieb, A., 1999 Hypothesis: from epidermal barrier dysfunction to atopic disorders. Contact Dermat. 41: 177-180.
52. Togias, A. 2004 Systemic effects of local allergic disease. J. Allergy Clin. Immunol. 113: S8-S14.
53. Trzeciak, M., J. Glen, J. Roszkiewicz, and B. Nedoszytko, 2010 Association of single nucleotide polymorphism of interleukin-18 with atopic dermatitis. J. Eur. Acad. Dermatol. Venereol. 24: 78-79.
54. Walley, A. J., S. Chavanas, M. F. Moffatt, R. M. Esnouf, B. Ubhi et al., 2001 Gene polymorphism in Netherton and common atopic disease. Nat. Genet. 29: 175-178.
55. Weidinger, S., H. Baurecht, S. Wagenpfeil, J. Henderson, N. Novak et al., 2008 Analysis of the individual and aggregate genetic contributions of previously identified serine peptidase inhibitor Kazal type 5 (SPINK5), kallikrein-related peptidase 7 (KLK7), and filaggrin (FLG) polymorphisms to eczema risk. J. Allergy Clin. Immunol. 122: 560-568.
56. Wood, S. H., D. N. Clements, N. A.McEwan, T. Nuttall et al., 2008 Reference genes for canine skin when using quantitative real-time PCR. Vet. Immunol. Immunopathol. 126: 392-395.
57. Wood, S. H., D. N. Clements, W. E. Ollier, T. Nuttall, N. A. McEwan et al., 2009 Gene expression in canine atopic dermatitis and correlation with clinical severity scores. J. Dermatol. Sci. 55: 27-33.
58. Wu, Z., B. Hansmann, U. Meyer-Hoffert, R. Glaser, and J. M. Schroder, 2009 Molecular identification and expression analysis of filaggrin-2, a member of the S100 fused-type protein family. PLoS ONE 4: e5227.
59. Wüthrich, B., 1978 Serum IgE in atopic dermatitis: relationship to severity of cutaneous involvement and course of disease as well as coexistence of atopic respiratory diseases. Clin. Allergy 8: 241-248.
60. Yamasaki, K., J. Schauber, A. Coda, H. Lin, R. A. Dorschner et al., 2006 Kallikrein-mediated proteolysis regulates the antimicrobial effects of cathelicidins in skin. FASEB J. 20: 2068-2080.