-
1
-
-
84874114984
-
Prevalence of diabetes mellitus in pancreatic cancer compared to common cancers
-
Aggarwal, G., Kamada, P., and Chari, ST. (2013). Prevalence of diabetes mellitus in pancreatic cancer compared to common cancers. Pancreas 42(2), 198-201. doi: 10.1097/MPA.0b013e3182592c96.
-
(2013)
Pancreas
, vol.42
, Issue.2
, pp. 198-201
-
-
Aggarwal, G.1
Kamada, P.2
Chari, S.T.3
-
2
-
-
84869816038
-
Adrenomedullin is up-regulated in patients with pancreatic cancer and causes insulin resistance in ß cells and mice
-
Aggarwal, G., Ramachandran, V., Javeed, N., Arumugam, T., Dutta, S., Klee, G.G., et al. (2012). Adrenomedullin is up-regulated in patients with pancreatic cancer and causes insulin resistance in ß cells and mice. Gastroenterology 143(6), 1510-1517. doi: 10.1053/j.gastro.2012.08.044.
-
(2012)
Gastroenterology
, vol.143
, Issue.6
, pp. 1510-1517
-
-
Aggarwal, G.1
Ramachandran, V.2
Javeed, N.3
Arumugam, T.4
Dutta, S.5
Klee, G.G.6
-
3
-
-
84863601677
-
Metformin reduces endogenous reactive oxygen species and associated DNA damage
-
Algire, C, Moiseeva, O., Deschênes-Simard, X., Amrein, L., Petruccelli, L., Birman, E., et al. (2012). Metformin reduces endogenous reactive oxygen species and associated DNA damage. Cancer Prev Res (Phila) 5(4), 536-543. doi: 10.1158/1940-6207.CAPR-11-0536.
-
(2012)
Cancer Prev Res (Phila)
, vol.5
, Issue.4
, pp. 536-543
-
-
Algire, C.1
Moiseeva, O.2
Deschênes-Simard, X.3
Amrein, L.4
Petruccelli, L.5
Birman, E.6
-
4
-
-
84908115589
-
Factors that affect risk for pancreatic disease in the general population: a systematic review and meta-analysis of prospective cohort studies
-
Alsamarrai, A., Das, S.L.M., Windsor, J.A., and Petrov, M.S. (2014). Factors that affect risk for pancreatic disease in the general population: a systematic review and meta-analysis of prospective cohort studies. Clin Gastroenterol Hepatol pii: S1542-3565(14), 00183-9. doi: 10.1016/j.cgh.2014.01.038.
-
(2014)
Clin Gastroenterol Hepatol
, pp. 00183-00189
-
-
Alsamarrai, A.1
Das, S.L.M.2
Windsor, J.A.3
Petrov, M.S.4
-
5
-
-
77952177097
-
Anthropometric measures, body mass index, and pancreatic cancer: a pooled analysis from the Pancreatic Cancer Cohort Consortium (PanScan)
-
Arslan, A.A., Helzlsouer, K.J., Kooperberg, C, Shu, X.O., Steplowski, E., Bueno-de-Mesquita, H.B., et al. (2010). Anthropometric measures, body mass index, and pancreatic cancer: a pooled analysis from the Pancreatic Cancer Cohort Consortium (PanScan). Arch Intern Med 170(9), 791-802. doi: 10.1001/archinternmed.2010.63.
-
(2010)
Arch Intern Med
, vol.170
, Issue.9
, pp. 791-802
-
-
Arslan, A.A.1
Helzlsouer, K.J.2
Kooperberg, C.3
Shu, X.O.4
Steplowski, E.5
Bueno-de-Mesquita, H.B.6
-
6
-
-
84859463669
-
Metformin inhibits cell proliferation, migration and invasion by attenuating CSC function mediated by deregulating miRNAs in pancreatic cancer cells
-
Bao, B., Wang, Z., Ali, S., Ahmad, A., Azmi, A.S., Sarkar, S.H., et al. (2012). Metformin inhibits cell proliferation, migration and invasion by attenuating CSC function mediated by deregulating miRNAs in pancreatic cancer cells. Cancer Prev Res 5(3), 355-364. doi: 10.1158/1940-6207.CAPR-11-0299.
-
(2012)
Cancer Prev Res
, vol.5
, Issue.3
, pp. 355-364
-
-
Bao, B.1
Wang, Z.2
Ali, S.3
Ahmad, A.4
Azmi, A.S.5
Sarkar, S.H.6
-
7
-
-
78651355589
-
The complexities of obesity and diabetes with the development and progression of pancreatic cancer
-
Bao, B., Wang, Z., Li, Y., Kong, D., Ali, S., Banerjee, S., et al. (2011). The complexities of obesity and diabetes with the development and progression of pancreatic cancer. Biochim Biophys Acta 1815(2), 135-146. doi: 10.1016/j.bbcan.2010.11.003.
-
(2011)
Biochim Biophys Acta
, vol.1815
, Issue.2
, pp. 135-146
-
-
Bao, B.1
Wang, Z.2
Li, Y.3
Kong, D.4
Ali, S.5
Banerjee, S.6
-
8
-
-
84872590843
-
A prospective study of plasma adiponectin and pancreatic cancer risk in five US cohorts
-
Bao, Y., Giovannucci, E.L., Kraft, P., Stampfer, M.J., Ogino, S., Ma, J., et al. (2013). A prospective study of plasma adiponectin and pancreatic cancer risk in five US cohorts. J Natl Cancer Inst 105(2), 95-103. doi: 10.1093/jnci/djs474.
-
(2013)
J Natl Cancer Inst
, vol.105
, Issue.2
, pp. 95-103
-
-
Bao, Y.1
Giovannucci, E.L.2
Kraft, P.3
Stampfer, M.J.4
Ogino, S.5
Ma, J.6
-
9
-
-
33747852700
-
Pancreatic cancer-derived S-100A8 N-terminal peptide: a diabetes cause?
-
Epub 2006 Mar 29
-
Basso, D., Greco, E., Fogar, P., Pucci, P., Flagiello, A., Baldo, G, et al. (2006). Pancreatic cancer-derived S-100A8 N-terminal peptide: a diabetes cause? Clin Chim Acta 372(1-2), 120-128. Epub 2006 Mar 29. doi: 10.1016/j.cca.2006.03.027.
-
(2006)
Clin Chim Acta
, vol.372
, Issue.1-2
, pp. 120-128
-
-
Basso, D.1
Greco, E.2
Fogar, P.3
Pucci, P.4
Flagiello, A.5
Baldo, G.6
-
10
-
-
79960204025
-
Diabetes mellitus and risk of pancreatic cancer: A meta-analysis of cohort studies
-
Ben, Q., Xu, M., Ning, X., Liu, J., Hong, S, Huang, W., et al. (2011). Diabetes mellitus and risk of pancreatic cancer: A meta-analysis of cohort studies. Eur J Cancer 47(13), 1928-1937. doi: 10.1016/j.ejca.2011.03.003.
-
(2011)
Eur J Cancer
, vol.47
, Issue.13
, pp. 1928-1937
-
-
Ben, Q.1
Xu, M.2
Ning, X.3
Liu, J.4
Hong, S.5
Huang, W.6
-
11
-
-
44849099894
-
The antidiabetic drug metformin exerts an antitumoral effect in vitro and in vivo through a decrease of cyclin D1 level
-
Ben Sahra, I., Laurent, K., Loubat, A., Giorgetti-Peraldi, S., Colosetti, P., Auberger, P., et al. (2008). The antidiabetic drug metformin exerts an antitumoral effect in vitro and in vivo through a decrease of cyclin D1 level. Oncogene 27(25), 3576-3586. doi: 10.1038/sj.onc.1211024.
-
(2008)
Oncogene
, vol.27
, Issue.25
, pp. 3576-3586
-
-
Ben Sahra, I.1
Laurent, K.2
Loubat, A.3
Giorgetti-Peraldi, S.4
Colosetti, P.5
Auberger, P.6
-
12
-
-
79959764729
-
Metformin, independent of AMPK, induces mTOR inhibition and cell-cycle arrest through REDD1
-
Ben Sahra, I., Regazzetti, C, Robert, G., Laurent, K., Le Marchand-Brustel, Y., Auberger, P., et al. (2011). Metformin, independent of AMPK, induces mTOR inhibition and cell-cycle arrest through REDD1. Cancer Res 71(13), 4366-4372. doi: 10.1158/0008-5472.CAN-10-1769.
-
(2011)
Cancer Res
, vol.71
, Issue.13
, pp. 4366-4372
-
-
Ben Sahra, I.1
Regazzetti, C.2
Robert, G.3
Laurent, K.4
Le Marchand-Brustel, Y.5
Auberger, P.6
-
13
-
-
8244254377
-
Improvements in survival and clinical benefit with gemcitabine as first-line therapy for patients with advanced pancreas cancer: a randomized trial
-
PMID: 9196156
-
Burris, H.A., Moore, M.J., Andersen, J., Green, M.R., Rothenberg, M.L., Modiano, M.R., et al. (1997). Improvements in survival and clinical benefit with gemcitabine as first-line therapy for patients with advanced pancreas cancer: a randomized trial. J Clin Oncol 15, 2403-2413. PMID: 9196156.
-
(1997)
J Clin Oncol
, vol.15
, pp. 2403-2413
-
-
Burris, H.A.1
Moore, M.J.2
Andersen, J.3
Green, M.R.4
Rothenberg, M.L.5
Modiano, M.R.6
-
14
-
-
79956008277
-
Management strategies in pancreatic cancer
-
Campen, C.J., Dragovich, T., and Baker, A.F. (2011). Management strategies in pancreatic cancer. Am J Health Syst Pharm 68(7), 573-584. doi: 10.2146/ajhp100254.
-
(2011)
Am J Health Syst Pharm
, vol.68
, Issue.7
, pp. 573-584
-
-
Campen, C.J.1
Dragovich, T.2
Baker, A.F.3
-
15
-
-
84892484894
-
Contextual inhibition of fatty acid synthesis by metformin involves glucose-derived acetyl-CoA and cholesterol in pancreatic tumor cells
-
Cantoria, M.J., Boros, L.G., and Meuillet, E.J. (2014). Contextual inhibition of fatty acid synthesis by metformin involves glucose-derived acetyl-CoA and cholesterol in pancreatic tumor cells. Metabolomics 10, 91-104. doi: 10.1007/s11306-013-0555-4.
-
(2014)
Metabolomics
, vol.10
, pp. 91-104
-
-
Cantoria, M.J.1
Boros, L.G.2
Meuillet, E.J.3
-
16
-
-
37349014799
-
Pancreatic cancer-associated diabetes mellitus: prevalence and temporal association with diagnosis of cancer
-
Chari, S.T., Leibson, C.L., Rabe, K.G, Timmons, L.J., Ransom, J., de Andrade, M., et al. (2008). Pancreatic cancer-associated diabetes mellitus: prevalence and temporal association with diagnosis of cancer. Gastroenterology 134(1), 95-101. doi: http://dx.doi.org/10.1053/j.gastro.2007.10.040.
-
(2008)
Gastroenterology
, vol.134
, Issue.1
, pp. 95-101
-
-
Chari, S.T.1
Leibson, C.L.2
Rabe, K.G.3
Timmons, L.J.4
Ransom, J.5
de Andrade, M.6
-
17
-
-
84904114424
-
Profiling and targeting of cellular bioenergetics: inhibition of pancreatic cancer cell proliferation
-
Cheng, G, Zielonka, J., McAllister, D., Tsai, S., Dwinell, M.B., and Kalyanaraman, B. (2014). Profiling and targeting of cellular bioenergetics: inhibition of pancreatic cancer cell proliferation. Br J Cancer 111, 85-93. doi:10.1038/bjc.2014.272.
-
(2014)
Br J Cancer
, vol.111
, pp. 85-93
-
-
Cheng, G.1
Zielonka, J.2
McAllister, D.3
Tsai, S.4
Dwinell, M.B.5
Kalyanaraman, B.6
-
18
-
-
79955921754
-
FOLFIRINOX versus gemcitabine for metastatic pancreatic cancer
-
Conroy, T., Desseigne, F., Ychou, M., Bouché, O., Guimbaud, R., Bécouarn, Y., et al (2011). FOLFIRINOX versus gemcitabine for metastatic pancreatic cancer. N Engl J Med 364(19), 1817-1825. doi: 10.1056/NEJMoa1011923.
-
(2011)
N Engl J Med
, vol.364
, Issue.19
, pp. 1817-1825
-
-
Conroy, T.1
Desseigne, F.2
Ychou, M.3
Bouché, O.4
Guimbaud, R.5
Bécouarn, Y.6
-
19
-
-
78649872745
-
Metformin against TGFß-induced epithelial-to-mesenchymal transition (EMT): from cancer stem cells to aging-associated fibrosis
-
Cufí, S., Vazquez-Martin, A., Oliveras-Ferraros, C, Martin-Castillo, B., Joven, J., and Menendez, J.A. (2010). Metformin against TGFß-induced epithelial-to-mesenchymal transition (EMT): from cancer stem cells to aging-associated fibrosis. Cell Cycle 9(22), 4461-4468. doi: 10.4161/cc.9.22.14048.
-
(2010)
Cell Cycle
, vol.9
, Issue.22
, pp. 4461-4468
-
-
Cufí, S.1
Vazquez-Martin, A.2
Oliveras-Ferraros, C.3
Martin-Castillo, B.4
Joven, J.5
Menendez, J.A.6
-
20
-
-
68449094325
-
The influence of glucose-lowering therapies on cancer risk in type 2 diabetes
-
Currie, C.J., Poole, CD., and Gale, E.A. (2009). The influence of glucose-lowering therapies on cancer risk in type 2 diabetes. Diabetologia 52(9), 1766-1777. doi: 10.1007/s00125-009-1440-6.
-
(2009)
Diabetologia
, vol.52
, Issue.9
, pp. 1766-1777
-
-
Currie, C.J.1
Poole, CD.2
Gale, E.A.3
-
21
-
-
84908364611
-
The anti-diabetic drug metformin perturbs proliferation and cellular differentiation of pancreatic cancer cells: a key mechanism of its anticancer activity (784.6)
-
Das, A., De, A., Maity, G. Banerjee, S., and Banerjee, S. (2014). The anti-diabetic drug metformin perturbs proliferation and cellular differentiation of pancreatic cancer cells: a key mechanism of its anticancer activity (784.6). The FASEB Journal 28, 784-786.
-
(2014)
The FASEB Journal
, vol.28
, pp. 784-786
-
-
Das, A.1
De, A.2
Maity G.Banerjee, S.3
Banerjee, S.4
-
22
-
-
84898858497
-
Diagnosis and management of pancreatic cancer
-
PubMed PMID: 24784121
-
De La Cruz, M.S., Young, A.P., and Ruffin, M.T. (2014). Diagnosis and management of pancreatic cancer. Am Fam Physician 89(8), 626-632. PubMed PMID: 24784121.
-
(2014)
Am Fam Physician
, vol.89
, Issue.8
, pp. 626-632
-
-
De La Cruz, M.S.1
Young, A.P.2
Ruffin, M.T.3
-
23
-
-
0033798639
-
Physiological concentrations of insulin augment pancreatic cancer cell proliferation and glucose utilization by activating MAP kinase, PI3 kinase and enhancing GLUT-1 expression
-
PubMed PMID: 11039477
-
Ding, X.Z., Fehsenfeld, D.M., Murphy, L.O., Permert, J., and Adrian, T.E. (2000). Physiological concentrations of insulin augment pancreatic cancer cell proliferation and glucose utilization by activating MAP kinase, PI3 kinase and enhancing GLUT-1 expression. Pancreas 21(3), 310-320. PubMed PMID: 11039477.
-
(2000)
Pancreas
, vol.21
, Issue.3
, pp. 310-320
-
-
Ding, X.Z.1
Fehsenfeld, D.M.2
Murphy, L.O.3
Permert, J.4
Adrian, T.E.5
-
24
-
-
79958272949
-
Mechanism of the mitogenic influence of hyperinsulinemia
-
Draznin, B. (2011). Mechanism of the mitogenic influence of hyperinsulinemia. Diabetol Metab Syndr 3(1), 10. doi: 10.1186/1758-5996-3-10.
-
(2011)
Diabetol Metab Syndr
, vol.3
, Issue.1
, pp. 10
-
-
Draznin, B.1
-
25
-
-
84871770725
-
Diabetes and risk of pancreatic cancer: a pooled analysis from the pancreatic cancer cohort consortium
-
Elena, J.W., Steplowski, E., Yu, K., Hartge, P., Tobias, G.S., Brotzman MJ, et al. (2013). Diabetes and risk of pancreatic cancer: a pooled analysis from the pancreatic cancer cohort consortium. Cancer Causes Control 24(1), 13-25. doi: 10.1007/s10552-012-0078-8.
-
(2013)
Cancer Causes Control
, vol.24
, Issue.1
, pp. 13-25
-
-
Elena, J.W.1
Steplowski, E.2
Yu, K.3
Hartge, P.4
Tobias, G.S.5
Brotzman, MJ.6
-
26
-
-
0034614420
-
Dimethylbiguanide inhibits cell respiration via an indirect effect targeted on the respiratory chain complex I
-
Pubmed PMID: 10617608
-
El-Mir, M.Y., Nogueira, V., Fontaine, E., Avéret, N., Riqoulet, M., and Leverve, X. (2000). Dimethylbiguanide inhibits cell respiration via an indirect effect targeted on the respiratory chain complex I. J Biol Chem 275(1), 223-228. Pubmed PMID: 10617608.
-
(2000)
J Biol Chem
, vol.275
, Issue.1
, pp. 223-228
-
-
El-Mir, M.Y.1
Nogueira, V.2
Fontaine, E.3
Avéret, N.4
Riqoulet, M.5
Leverve, X.6
-
27
-
-
20444461067
-
Metformin and reduced risk of cancer in diabetic patients
-
Evans, J.M., Donnelly, L.A., Emslie-Smith, A.M., Alessi, D.R., and Morris AD. (2005). Metformin and reduced risk of cancer in diabetic patients. BMJ 330(7503), 1304-1305. doi: http://dx.doi.org/10.1136/bmj.38415.708634.F7.
-
(2005)
BMJ
, vol.330
, Issue.7503
, pp. 1304-1305
-
-
Evans, J.M.1
Donnelly, L.A.2
Emslie-Smith, A.M.3
Alessi, D.R.4
Morris, AD.5
-
28
-
-
0029017953
-
Diabetes mellitus as a risk factor for pancreatic cancer. A meta-analysis.
-
Everhart J., and Wright, D. (1995). Diabetes mellitus as a risk factor for pancreatic cancer. A meta-analysis. JAMA 273(20), 1605-1609. doi: 10.1001/jama.1995.03520440059037.
-
(1995)
JAMA
, vol.273
, Issue.20
, pp. 1605-1609
-
-
Everhart, J.1
Wright, D.2
-
29
-
-
84904112514
-
Radiosensitization of pancreatic cancer cells by metformin through the AMPK pathway
-
Fasih, A., Elbaz, H.A., Hüttemann, M., Konski, A.A., and Zielske S.P. (2014). Radiosensitization of pancreatic cancer cells by metformin through the AMPK pathway. Radiat Res 182(1), 50-59. doi: 10.1667/RR13568.1.
-
(2014)
Radiat Res
, vol.182
, Issue.1
, pp. 50-59
-
-
Fasih, A.1
Elbaz, H.A.2
Hüttemann, M.3
Konski, A.A.4
Zielske, S.P.5
-
30
-
-
0028641452
-
Diabetes mellitus in pancreatic cancer follow-up
-
PubMed PMID: 7532931
-
Fogar, P., Pasquali, C., Basso, D., Sperti, C., Panozzo, M.P., Tessari, G., et al. (1994). Diabetes mellitus in pancreatic cancer follow-up. Anticancer Res 14(6B), 2827-2830. PubMed PMID: 7532931.
-
(1994)
Anticancer Res
, vol.14 B
, Issue.6
, pp. 2827-2830
-
-
Fogar, P.1
Pasquali, C.2
Basso, D.3
Sperti, C.4
Panozzo, M.P.5
Tessari, G.6
-
31
-
-
79960923640
-
A pooled analysis of 14 cohort studies of anthropometric factors and pancreatic cancer risk
-
Genkinger, J.M., Spiegelman, D., Anderson, K.E., Bernstein, L., van den Brandt, P.A., Calle, E.E., et al. (2011). A pooled analysis of 14 cohort studies of anthropometric factors and pancreatic cancer risk. Int J Cancer 129(7), 1708-1717. doi: 10.1002/ijc.25794.
-
(2011)
Int J Cancer
, vol.129
, Issue.7
, pp. 1708-1717
-
-
Genkinger, J.M.1
Spiegelman, D.2
Anderson, K.E.3
Bernstein, L.4
Den Brandt, P.A.5
Calle, E.E.6
-
32
-
-
84895890605
-
Optimum chemotherapy in the management of metastatic pancreatic cancer
-
Ghosn, M., Kourie, H.R., El Karak, F., Hanna, C., Antoun, J., and Nasr, D. (2014). Optimum chemotherapy in the management of metastatic pancreatic cancer. World J Gastroenterol 20(9), 2352-2357. doi: 10.3748/wjg.v20.i9.2352.
-
(2014)
World J Gastroenterol
, vol.20
, Issue.9
, pp. 2352-2357
-
-
Ghosn, M.1
Kourie, H.R.2
El Karak, F.3
Hanna, C.4
Antoun, J.5
Nasr, D.6
-
33
-
-
71449120059
-
Insulin resistance and hyperinsulinaemia in the development and progression of cancer
-
Godsland, I.F. (2009). Insulin resistance and hyperinsulinaemia in the development and progression of cancer. Clin Sci (Lond) 118(5),315-332. doi: 10.1042/CS20090399.
-
(2009)
Clin Sci (Lond)
, vol.118
, Issue.5
, pp. 315-332
-
-
Godsland, I.F.1
-
34
-
-
84877259011
-
Low concentrations of metformin selectively inhibit CD133+ cell proliferation in pancreatic cancer and have anticancer action
-
Gou, S., Cui, P., Li, X., Shi, P., Liu, T., and Wang, C. (2013). Low concentrations of metformin selectively inhibit CD133+ cell proliferation in pancreatic cancer and have anticancer action. PLoS One 8(5), e63969. doi: 10.1371/journal.pone.0063969.
-
(2013)
PLoS One
, vol.8
, Issue.5
, pp. e63969
-
-
Gou, S.1
Cui, P.2
Li, X.3
Shi, P.4
Liu, T.5
Wang, C.6
-
35
-
-
84872529696
-
Metformin inhibits the inflammatory response associated with cellular transformation and cancer stem cell growth
-
Hirsch, H.A., Iliopoulos, D., and Struhl, K. (2013). Metformin inhibits the inflammatory response associated with cellular transformation and cancer stem cell growth. Proc Natl Acad Sci USA 110(3), 972-977. doi: 10.1073/pnas.1221055110.
-
(2013)
Proc Natl Acad Sci USA
, vol.110
, Issue.3
, pp. 972-977
-
-
Hirsch, H.A.1
Iliopoulos, D.2
Struhl, K.3
-
36
-
-
79958043675
-
-
National Cancer Institute. Bethesda, MD, based on November 2013 SEER data submission, posted to the SEER web site, April 2014.
-
Howlader, N., Noone, A.M., Krapcho, M., Garshell, J., Miller, D., Altekruse, S.F., et al. ed. (2014). SEER Cancer Statistics Review, 1975-2011, National Cancer Institute. Bethesda, MD, http://seer.cancer.gov/csr/1975_2011/, based on November 2013 SEER data submission, posted to the SEER web site, April 2014.
-
(2014)
SEER Cancer Statistics Review, 1975-2011
-
-
Howlader, N.1
Noone, A.M.2
Krapcho, M.3
Garshell, J.4
Miller, D.5
Altekruse, S.F.6
-
37
-
-
21244485747
-
Type-II diabetes and pancreatic cancer: a meta-analysis of 36 studies
-
Huxley, R., Ansary-Moghaddam, A., Berrington de González, A., Barzi, F., and Woodward M. (2005). Type-II diabetes and pancreatic cancer: a meta-analysis of 36 studies. Br J Cancer 92(11), 2076-2083. doi: 10.1038/sj.bjc.6602619.
-
(2005)
Br J Cancer
, vol.92
, Issue.11
, pp. 2076-2083
-
-
Huxley, R.1
Ansary-Moghaddam, A.2
Berrington de González, A.3
Barzi, F.4
Woodward, M.5
-
38
-
-
79955490053
-
Metformin decreases the dose of chemotherapy for prolonging tumor remission in mouse xenografts involving multiple cancer cell types
-
Iliopoulos, D., Hirsch, H.A., and Struhl, K. (2011). Metformin decreases the dose of chemotherapy for prolonging tumor remission in mouse xenografts involving multiple cancer cell types. Cancer Res 71(9), 3196-3201. doi: 10.1158/0008-5472.CAN-10-3471.
-
(2011)
Cancer Res
, vol.71
, Issue.9
, pp. 3196-3201
-
-
Iliopoulos, D.1
Hirsch, H.A.2
Struhl, K.3
-
39
-
-
43149114451
-
Tobacco and the risk of pancreatic cancer: a review and meta-analysis
-
Iodice, S., Gandini, S., Maisonneuve, P., and Lowenfels, A.B. (2008). Tobacco and the risk of pancreatic cancer: a review and meta-analysis. Langenbecks Arch Surg 393(4), 535-545. doi: 10.1007/s00423-007-0266-2.
-
(2008)
Langenbecks Arch Surg
, vol.393
, Issue.4
, pp. 535-545
-
-
Iodice, S.1
Gandini, S.2
Maisonneuve, P.3
Lowenfels, A.B.4
-
40
-
-
77955923866
-
Metformin: taking away the candy for cancer?
-
Jalving, M., Gietema, J.A., Lefrandt, J.D., de Jong, S., Reyners, A.K., Gans, R.O., et al. (2010). Metformin: taking away the candy for cancer? Eur J Cancer 46(13), 2369-2380. doi: 10.1016/j.ejca.2010.06.012.
-
(2010)
Eur J Cancer
, vol.46
, Issue.13
, pp. 2369-2380
-
-
Jalving, M.1
Gietema, J.A.2
Lefrandt, J.D.3
de Jong, S.4
Reyners, A.K.5
Gans, R.O.6
-
41
-
-
77955713296
-
Body mass index, effect modifiers, and risk of pancreatic cancer: a pooled study of seven prospective cohorts
-
Jiao, L., Berrington de Gonzalez, A., Hartge, P., Pfeiffer, R.M., Park, Y., Freedman, D.M., et al. (2010). Body mass index, effect modifiers, and risk of pancreatic cancer: a pooled study of seven prospective cohorts. Cancer Causes Control 21(8), 1305-1314. doi: 10.1007/s10552-010-9558-x.
-
(2010)
Cancer Causes Control
, vol.21
, Issue.8
, pp. 1305-1314
-
-
Jiao, L.1
Berrington de Gonzalez, A.2
Hartge, P.3
Pfeiffer, R.M.4
Park, Y.5
Freedman, D.M.6
-
42
-
-
77955287742
-
Metformin, independent of AMPK, inhibits mTORC1 in a rag GTPase-dependent manner
-
Kalender, A., Selvaraj, A., Kim, S.Y., Gulati, P., Brûlé, S., Viollet, B., et al. (2010). Metformin, independent of AMPK, inhibits mTORC1 in a rag GTPase-dependent manner. Cell Metab 11(5), 390-401. doi: 10.1016/j.cmet.2010.03.014.
-
(2010)
Cell Metab
, vol.11
, Issue.5
, pp. 390-401
-
-
Kalender, A.1
Selvaraj, A.2
Kim, S.Y.3
Gulati, P.4
Brûlé, S.5
Viollet, B.6
-
43
-
-
84877251996
-
Metformin-mediated growth inhibition involves suppression of the IGF-I receptor signalling pathway in human pancreatic cancer cells
-
Karnevi, E., Said, K., Andersson, R., and Rosendahl, A.H. (2013). Metformin-mediated growth inhibition involves suppression of the IGF-I receptor signalling pathway in human pancreatic cancer cells. BMC Cancer 13, 325. doi: 10.1186/1471-2407-13-235.
-
(2013)
BMC Cancer
, vol.13
, pp. 325
-
-
Karnevi, E.1
Said, K.2
Andersson, R.3
Rosendahl, A.H.4
-
44
-
-
69249162223
-
Metformin disrupts crosstalk between G protein-coupled receptor and insulin receptor signaling systems and inhibits pancreatic cancer growth
-
Kisfalvi, K., Eibl, G., Sinnett-Smith, J., and Rozengurt, E. (2009). Metformin disrupts crosstalk between G protein-coupled receptor and insulin receptor signaling systems and inhibits pancreatic cancer growth. Cancer Res 69, 6539-6545. doi: 10.1158/0008-5472.CAN-09-0418.
-
(2009)
Cancer Res
, vol.69
, pp. 6539-6545
-
-
Kisfalvi, K.1
Eibl, G.2
Sinnett-Smith, J.3
Rozengurt, E.4
-
45
-
-
84880047529
-
Metformin inhibits the growth of human pancreatic cancer xenografts
-
Kisfalvi, K., Moro, A., Sinnett-Smith, J., Eibl, G., and Rozengurt, E. (2013). Metformin inhibits the growth of human pancreatic cancer xenografts. Pancreas 42(5), 781-785. doi: 10.1097/MPA.0b013e31827aec40.
-
(2013)
Pancreas
, vol.42
, Issue.5
, pp. 781-785
-
-
Kisfalvi, K.1
Moro, A.2
Sinnett-Smith, J.3
Eibl, G.4
Rozengurt, E.5
-
46
-
-
84863477848
-
Pancreatic cancer: mouse models link metabolism and deubiquitination with Kras
-
Kirk, R. (2012). Pancreatic cancer: mouse models link metabolism and deubiquitination with Kras. Nat Rev Clin Oncol 9(7), 368. doi:10.1038/nrclinonc.2012.85.
-
(2012)
Nat Rev Clin Oncol
, vol.9
, Issue.7
, pp. 368
-
-
Kirk, R.1
-
47
-
-
33947191596
-
Body mass index and pancreatic cancer risk: a meta-analysis of prospective studies
-
Larsson, S.C., Orsini, N., and Wolk, A. (2007). Body mass index and pancreatic cancer risk: a meta-analysis of prospective studies. Int J Cancer 120(9), 1993-1998. doi: 10.1002/ijc.22535.
-
(2007)
Int J Cancer
, vol.120
, Issue.9
, pp. 1993-1998
-
-
Larsson, S.C.1
Orsini, N.2
Wolk, A.3
-
48
-
-
83455196951
-
Diabetes and pancreatic cancer
-
Li, D,. (2012). Diabetes and pancreatic cancer. Mol Carcinog 51(1), 64-74. doi: 10.1002/mc.20771.
-
(2012)
Mol Carcinog
, vol.51
, Issue.1
, pp. 64-74
-
-
Li, D.1
-
49
-
-
84862777219
-
Metformin alters the expression profiles of microRNAs in human pancreatic cancer cells
-
Li, W., Yuan, Y., Huang, L., Qiao, M., and Zhang, Y. (2012). Metformin alters the expression profiles of microRNAs in human pancreatic cancer cells. Diabetes Res Clin Pract 96(2), 187-195. doi: 10.1016/j.diabres.2011.12.028.
-
(2012)
Diabetes Res Clin Pract
, vol.96
, Issue.2
, pp. 187-195
-
-
Li, W.1
Yuan, Y.2
Huang, L.3
Qiao, M.4
Zhang, Y.5
-
50
-
-
84885742331
-
Metformin targets the metabolic Achilles heel of human pancreatic cancer stem cells
-
Lonardo, E., Cioffi, M., Sancho, P., Sanchez-Ripoll, Y., Trabulo, S.M., Dorado, J., et al. (2013). Metformin targets the metabolic Achilles heel of human pancreatic cancer stem cells. PLOS One 8(10), e76518. doi:10.1371/journal.pone.0076518.
-
(2013)
PLOS One
, vol.8
, Issue.10
, pp. e76518
-
-
Lonardo, E.1
Cioffi, M.2
Sancho, P.3
Sanchez-Ripoll, Y.4
Trabulo, S.M.5
Dorado, J.6
-
51
-
-
0030975440
-
Hereditary pancreatitis and the risk of pancreatic cancer
-
Lowenfels, A.B., Maisonneuve, P., DiMagno, E.P., Elitsur, Y., Gates, L.K., Jr, Perrault, J., et al. (1997). Hereditary pancreatitis and the risk of pancreatic cancer. J Natl Cancer Inst 89(6), 442-446. doi: 10.1093/jnci/89.6.442.
-
(1997)
J Natl Cancer Inst
, vol.89
, Issue.6
, pp. 442-446
-
-
Lowenfels, A.B.1
Maisonneuve, P.2
DiMagno, E.P.3
Elitsur, Y.4
Gates, L.K.5
Jr Perrault, J.6
-
52
-
-
77950188361
-
IGF-1 mediates PTEN suppression and enhances cell invasion and proliferation via activation of the IGF 1/PI3K/Akt signaling pathway in pancreatic cancer cells
-
Ma, J., Sawai, H., Matsuo, Y., Ochi, N., Yasuda, A., Takahashi, H., et al. (2010). IGF-1 mediates PTEN suppression and enhances cell invasion and proliferation via activation of the IGF 1/PI3K/Akt signaling pathway in pancreatic cancer cells. J Surg Res 160(1), 90-101. doi: 10.1016/j.jss.2008.08.016.
-
(2010)
J Surg Res
, vol.160
, Issue.1
, pp. 90-101
-
-
Ma, J.1
Sawai, H.2
Matsuo, Y.3
Ochi, N.4
Yasuda, A.5
Takahashi, H.6
-
53
-
-
84891723543
-
Antidiabetic drug metformin prevents progression of pancreatic cancer by targeting in part cancer stem cells and mTOR signaling
-
Pubmed PMID: 24466367
-
Mohammed, A., Janakiram, N.B., Brewer, M., Ritchie, R.L., Marya, A., Lightfoot, S., et al. (2013). Antidiabetic drug metformin prevents progression of pancreatic cancer by targeting in part cancer stem cells and mTOR signaling. Transl Oncol 6(6), 649-659. Pubmed PMID: 24466367.
-
(2013)
Transl Oncol
, vol.6
, Issue.6
, pp. 649-659
-
-
Mohammed, A.1
Janakiram, N.B.2
Brewer, M.3
Ritchie, R.L.4
Marya, A.5
Lightfoot, S.6
-
54
-
-
84905579496
-
Targeting mTOR dependency in pancreatic cancer
-
Morran, D.C., Wu, J., Jamieson, N.B., Mrowinska, A., Kalna, G., Karim, S.A., et al. (2014). Targeting mTOR dependency in pancreatic cancer. Gut 0, 1-9. doi:10.1136/gutjnl-2013-306202.
-
(2014)
Gut
, vol.0
, pp. 1-9
-
-
Morran, D.C.1
Wu, J.2
Jamieson, N.B.3
Mrowinska, A.4
Kalna, G.5
Karim, S.A.6
-
55
-
-
84889011636
-
Metformin inhibits pancreatic cancer cell and tumor growth and downregulates Sp transcription factors
-
Nair, V., Pathi, S., Jutooru, I., Sreevalsan, S., Basha, R., Abdelrahim, M., et al. (2013). Metformin inhibits pancreatic cancer cell and tumor growth and downregulates Sp transcription factors. Carcinogenesis 34(12), 2870-2879. doi: 10.1093/carcin/bgt231.
-
(2013)
Carcinogenesis
, vol.34
, Issue.12
, pp. 2870-2879
-
-
Nair, V.1
Pathi, S.2
Jutooru, I.3
Sreevalsan, S.4
Basha, R.5
Abdelrahim, M.6
-
56
-
-
84907495391
-
Mechanism of metformin-dependent inhibition of mammalian target of rapamycin (mTOR) and Ras activity in pancreatic cancer: role of specificity protein (Sp) transcription factors
-
Nair, V., Sreevalsan, S., Basha, R., Abdelrahim, M., Abudayyeh, A., Hoffman, A.R., et al. (2014). Mechanism of metformin-dependent inhibition of mammalian target of rapamycin (mTOR) and Ras activity in pancreatic cancer: role of specificity protein (Sp) transcription factors. J Biol Chem 289(40), 27692-27701. doi: 10.1074/jbc.M114.592576.
-
(2014)
J Biol Chem
, vol.289
, Issue.40
, pp. 27692-27701
-
-
Nair, V.1
Sreevalsan, S.2
Basha, R.3
Abdelrahim, M.4
Abudayyeh, A.5
Hoffman, A.R.6
-
57
-
-
84902290137
-
Metformin suppresses Sonic hedgehog expression in pancreatic cancer cells
-
Pubmed PMID: PMID: 24692708
-
Nakamura, M., Ogo, A., Yamura, M., Yamaguchi, Y., and Nakashima, H. (2014). Metformin suppresses Sonic hedgehog expression in pancreatic cancer cells. Anticancer Research 34(4), 1765-1769. Pubmed PMID: PMID: 24692708.
-
(2014)
Anticancer Research
, vol.34
, Issue.4
, pp. 1765-1769
-
-
Nakamura, M.1
Ogo, A.2
Yamura, M.3
Yamaguchi, Y.4
Nakashima, H.5
-
58
-
-
41349090088
-
Prevalence and clinical profile of pancreatic cancer-associated diabetes mellitus
-
Pannala, R., Leirness, J.B., Bamlet, W.R., Basu, A., Petersen, G.M., and Chari, S.T. (2008). Prevalence and clinical profile of pancreatic cancer-associated diabetes mellitus. Gastroenterology 134(4), 981-987. doi: 10.1053/j.gastro.2008.01.039.
-
(2008)
Gastroenterology
, vol.134
, Issue.4
, pp. 981-987
-
-
Pannala, R.1
Leirness, J.B.2
Bamlet, W.R.3
Basu, A.4
Petersen, G.M.5
Chari, S.T.6
-
59
-
-
0027242101
-
Improved glucose metabolism after subtotal pancreatectomy for pancreatic cancer
-
Permert, J., Ihse, I., Jorfeldt, L., von Schenck, H., Arnquist, H.J., and Larsson, J. (1993). Improved glucose metabolism after subtotal pancreatectomy for pancreatic cancer. Br J Surg 80(8), 1047-1050. doi: 10.1002/bjs.1800800841.
-
(1993)
Br J Surg
, vol.80
, Issue.8
, pp. 1047-1050
-
-
Permert, J.1
Ihse, I.2
Jorfeldt, L.3
von Schenck, H.4
Arnquist, H.J.5
Larsson, J.6
-
60
-
-
0027521023
-
Pancreatic cancer is associated with impaired glucose metabolism
-
PubMed PMID: 8098623
-
Permert, J., Ihse, I., Jorfeldt, L., von Schenck, H., Arnqvist, H.J., and Larsson, J. (1993). Pancreatic cancer is associated with impaired glucose metabolism. Eur J Surg 159(2), 101-107. PubMed PMID: 8098623.
-
(1993)
Eur J Surg
, vol.159
, Issue.2
, pp. 101-107
-
-
Permert, J.1
Ihse, I.2
Jorfeldt, L.3
von Schenck, H.4
Arnqvist, H.J.5
Larsson, J.6
-
61
-
-
0028054783
-
Islet amyloid polypeptide in patients with pancreatic cancer and diabetes
-
Permert, J., Larsson, J., Westermark, G.T., Herrington, M.K., Christmanson, L., Pour, P.M., et al. (1994). Islet amyloid polypeptide in patients with pancreatic cancer and diabetes. N Engl J Med 330(5), 313-318. doi: 10.1056/NEJM199402033300503.
-
(1994)
N Engl J Med
, vol.330
, Issue.5
, pp. 313-318
-
-
Permert, J.1
Larsson, J.2
Westermark, G.T.3
Herrington, M.K.4
Christmanson, L.5
Pour, P.M.6
-
62
-
-
3042781558
-
Insulin-like growth factors and neoplasia
-
Pollak, M.N., Schernhammer, E.S., and Hankinson, S.E. (2004). Insulin-like growth factors and neoplasia. Nat Rev Cancer 4(7), 505-518. doi: 10.1038/nrc1387.
-
(2004)
Nat Rev Cancer
, vol.4
, Issue.7
, pp. 505-518
-
-
Pollak, M.N.1
Schernhammer, E.S.2
Hankinson, S.E.3
-
63
-
-
0026052697
-
Insulin inhibits transcription of the human gene for insulin-like growth factor-binding protein-1
-
PubMed PMID: 1717456
-
Powell, D.R., Suwanichkul, A., Cubbage, M.L., DePaolis, L.A., Snuggs, M.B., and Lee, P.D. (1991). Insulin inhibits transcription of the human gene for insulin-like growth factor-binding protein-1. J Biol Chem 266(28), 18868-18876. PubMed PMID: 1717456.
-
(1991)
J Biol Chem
, vol.266
, Issue.28
, pp. 18868-18876
-
-
Powell, D.R.1
Suwanichkul, A.2
Cubbage, M.L.3
DePaolis, L.A.4
Snuggs, M.B.5
Lee, P.D.6
-
64
-
-
77956194328
-
Pancreatic cancer in chronic pancreatitis; aetiology, incidence, and early detection
-
Raimondi, S., Lowenfels, A.B., Morselli-Labate, A.M., Maisonneuve, P., and Pezzilli, R. (2010). Pancreatic cancer in chronic pancreatitis; aetiology, incidence, and early detection. Best Pract Res Clin Gastroenterol 24(3), 349-358. doi: 10.1016/j.bpg.2010.02.007.
-
(2010)
Best Pract Res Clin Gastroenterol
, vol.24
, Issue.3
, pp. 349-358
-
-
Raimondi, S.1
Lowenfels, A.B.2
Morselli-Labate, A.M.3
Maisonneuve, P.4
Pezzilli, R.5
-
65
-
-
84911863692
-
Mechanistic target of rapamycin (mTOR): a point of convergence in the action of insulin/IGF-1 and G protein-coupled receptor agonists in pancreatic cancer cells
-
Rozengurt, E. (2014). Mechanistic target of rapamycin (mTOR): a point of convergence in the action of insulin/IGF-1 and G protein-coupled receptor agonists in pancreatic cancer cells. Front Physiol 5(357), 1-8. doi: 10.3389/fphys.2014.00357.
-
(2014)
Front Physiol
, vol.5
, Issue.357
, pp. 1-8
-
-
Rozengurt, E.1
-
66
-
-
77951708711
-
Crosstalk between insulin/insulin-like growth factor-1 receptors and G protein-coupled receptor signaling systems: a novel target for the antidiabetic drug metformin in pancreatic cancer
-
Rozengurt, E., Sinnett-Smith, J., and Kisfalvi, K. (2010). Crosstalk between insulin/insulin-like growth factor-1 receptors and G protein-coupled receptor signaling systems: a novel target for the antidiabetic drug metformin in pancreatic cancer. Clin Cancer Res 16, 2505-2511. doi: 10.1158/1078-0432.CCR-09-2229.
-
(2010)
Clin Cancer Res
, vol.16
, pp. 2505-2511
-
-
Rozengurt, E.1
Sinnett-Smith, J.2
Kisfalvi, K.3
-
67
-
-
84891711129
-
A modular and flexible ESC-based mouse model of pancreatic cancer
-
Saborowski, M., Saborowski, A., Morris, J.P., Bosbach, B., Dow, L.E., Pelletier, J., et al. (2014). A modular and flexible ESC-based mouse model of pancreatic cancer. Genes & Dev 28(1), 85-97. doi: 10.1101/gad.232082.113.
-
(2014)
Genes & Dev
, vol.28
, Issue.1
, pp. 85-97
-
-
Saborowski, M.1
Saborowski, A.2
Morris, J.P.3
Bosbach, B.4
Dow, L.E.5
Pelletier, J.6
-
68
-
-
84861127026
-
Metformin use is associated with better survival of diabetic patients with pancreatic cancer
-
Sadeghi, N., Abbruzzese, J.L., Yeung, S.J., Hassan, M., and Li, D. (2012). Metformin use is associated with better survival of diabetic patients with pancreatic cancer. Clin Cancer Res 18(10), 2905-2912. doi: 10.1158/1078-0432.CCR-11-2994.
-
(2012)
Clin Cancer Res
, vol.18
, Issue.10
, pp. 2905-2912
-
-
Sadeghi, N.1
Abbruzzese, J.L.2
Yeung, S.J.3
Hassan, M.4
Li, D.5
-
69
-
-
84879974685
-
New insights into pancreatic cancer-induced paraneoplastic diabetes
-
Sah, R.P., Nagpal, S.J., Mukhopadhyay, D., and Chari, S.T. (2013). New insights into pancreatic cancer-induced paraneoplastic diabetes. Nat Rev Gastroenterol Hepatol 10(7), 423-433. doi: 10.1038/nrgastro.2013.49.
-
(2013)
Nat Rev Gastroenterol Hepatol
, vol.10
, Issue.7
, pp. 423-433
-
-
Sah, R.P.1
Nagpal, S.J.2
Mukhopadhyay, D.3
Chari, S.T.4
-
70
-
-
0035082644
-
Prevention of pancreatic cancer induction in hamsters by metformin
-
Schneider, M.B., Matsuzaki, H., Haorah, J., Ulrich, A., Standop, J., Ding XZ, et al. (2001). Prevention of pancreatic cancer induction in hamsters by metformin. Gastroenterology 120(5), 1263-1270. doi: http://dx.doi.org/10.1053/gast.2001.23258.
-
(2001)
Gastroenterology
, vol.120
, Issue.5
, pp. 1263-1270
-
-
Schneider, M.B.1
Matsuzaki, H.2
Haorah, J.3
Ulrich, A.4
Standop, J.5
Ding, XZ.6
-
71
-
-
84866595004
-
Pancreatic adenocarcinoma: ESMO-ESDO clinical practice guidelines for diagnosis, treatment and followup
-
Seufferlein, T., Bachet, J.B., Van Cutsem, E., and Rougier, P. (2012). Pancreatic adenocarcinoma: ESMO-ESDO clinical practice guidelines for diagnosis, treatment and followup. Ann Oncol 23(Suppl 7), 733-740. doi: 10.1093/annonc/mds224.
-
(2012)
Ann Oncol
, vol.23
, pp. 733-740
-
-
Seufferlein, T.1
Bachet, J.B.2
Van Cutsem, E.3
Rougier, P.4
-
72
-
-
84872412569
-
Metformin inhibition of mTORC1 activation, DNA synthesis and proliferation in pancreatic cancer cells: dependence on glucose concentration and role of AMPK
-
Sinnett-Smith, J., Kisfalvi, K., Kui, R., and Rozengurt, E. (2012). Metformin inhibition of mTORC1 activation, DNA synthesis and proliferation in pancreatic cancer cells: dependence on glucose concentration and role of AMPK. Biochem Biophys Res Commun 430(1), 352-357. doi: 10.1016/j.bbrc.2012.11.010.
-
(2012)
Biochem Biophys Res Commun
, vol.430
, Issue.1
, pp. 352-357
-
-
Sinnett-Smith, J.1
Kisfalvi, K.2
Kui, R.3
Rozengurt, E.4
-
73
-
-
84912058780
-
In vitro and in vivo biological evaluation of O-carboxymethyl chitosan encapsulated metformin nanoparticles for pancreatic cancer therapy
-
Snima, K.S., Jayakumar, R., Lakshmanan, V.K. (2014). In vitro and in vivo biological evaluation of O-carboxymethyl chitosan encapsulated metformin nanoparticles for pancreatic cancer therapy. Pharm Res 2014, 1-10. doi: 10.1007/s11095-014-1425-0.
-
(2014)
Pharm Res
, vol.2014
, pp. 1-10
-
-
Snima, K.S.1
Jayakumar, R.2
Lakshmanan, V.K.3
-
74
-
-
84861651472
-
OCarboxymethyl chitosan nanoparticles for metformin delivery to pancreatic cancer cells
-
Snima, K.S., Jayakumar, R., Unnikrishnan, A.G., Nair, S.V., and Lakshmanan, V.K. (2012). OCarboxymethyl chitosan nanoparticles for metformin delivery to pancreatic cancer cells. Carbohydrate Polymers 89(3), 1003-1007. doi: 10.1016/j.carbpol.2012.04.050.
-
(2012)
Carbohydrate Polymers
, vol.89
, Issue.3
, pp. 1003-1007
-
-
Snima, K.S.1
Jayakumar, R.2
Unnikrishnan, A.G.3
Nair, S.V.4
Lakshmanan, V.K.5
-
75
-
-
84874310577
-
Different patterns of Akt and ERK feedback activation in response to rapamycin, active-site mTOR inhibitors and metformin in pancreatic cancer cells
-
Soares, H.P., Ni, Y., Kisfalvi, K., Sinnett-Smith, J., and Rozengurt, E. (2013). Different patterns of Akt and ERK feedback activation in response to rapamycin, active-site mTOR inhibitors and metformin in pancreatic cancer cells. PLOS One 8(2), e57289. doi: 10.1371/journal.pone.0057289.
-
(2013)
PLOS One
, vol.8
, Issue.2
, pp. e57289
-
-
Soares, H.P.1
Ni, Y.2
Kisfalvi, K.3
Sinnett-Smith, J.4
Rozengurt, E.5
-
76
-
-
84875894714
-
Glutamine supports pancreatic cancer growth through a KRAS-regulated metabolic pathway
-
Son, J., Lyssiotis, C.A., Ying, H., Wang, X., Hua, S., Ligorio, M., et al. (2013). Glutamine supports pancreatic cancer growth through a KRAS-regulated metabolic pathway. Nature 496, 101-105. doi:10.1038/nature12040.
-
(2013)
Nature
, vol.496
, pp. 101-105
-
-
Son, J.1
Lyssiotis, C.A.2
Ying, H.3
Wang, X.4
Hua, S.5
Ligorio, M.6
-
77
-
-
74949137279
-
Alcohol drinking and pancreatic cancer risk: a meta-analysis of the dose-risk relation
-
Tramacere, I., Scotti, L., Jenab, M., Bagnardi, V., Bellocco, R., Rota, M., et al. (2010). Alcohol drinking and pancreatic cancer risk: a meta-analysis of the dose-risk relation. Int J Cancer 126(6), 1474-1486. doi: 10.1002/ijc.24936.
-
(2010)
Int J Cancer
, vol.126
, Issue.6
, pp. 1474-1486
-
-
Tramacere, I.1
Scotti, L.2
Jenab, M.3
Bagnardi, V.4
Bellocco, R.5
Rota, M.6
-
78
-
-
84911861458
-
Oncogene ablation-resistant pancreatic cancer cells depend on mitochondrial function
-
Viale, A., Pettazzoni, P., Lyssiotis, C.A., Ying, H., Sánchez, N., Marchesini, M., et al. (2014). Oncogene ablation-resistant pancreatic cancer cells depend on mitochondrial function. Nature 2014, 1-8. doi:10.1038/nature13611.
-
(2014)
Nature
, vol.2014
, pp. 1-8
-
-
Viale, A.1
Pettazzoni, P.2
Lyssiotis, C.A.3
Ying, H.4
Sánchez, N.5
Marchesini, M.6
-
79
-
-
65849256893
-
Metformin induces apoptosis of pancreatic cancer cells
-
Wang, L.W., Li, Z.S., Zou, D.W., Jin, Z.D., Gao, J., and Xu, G.M. (2008). Metformin induces apoptosis of pancreatic cancer cells. World J Gastroenterol 14(47), 7192-7198. doi: 10.3748/wjg.14.7192.
-
(2008)
World J Gastroenterol
, vol.14
, Issue.47
, pp. 7192-7198
-
-
Wang, L.W.1
Li, Z.S.2
Zou, D.W.3
Jin, Z.D.4
Gao, J.5
Xu, G.M.6
-
80
-
-
84908028466
-
Metformin is associated with reduced risk of pancreatic cancer in patients with type 2 diabetes mellitus: a systematic review and meta-analysis
-
Wang, Z., Lai, S.T., Xie, L., Zhao, J.D., Ma, N.Y., Zhu, J., et al. (2014). Metformin is associated with reduced risk of pancreatic cancer in patients with type 2 diabetes mellitus: a systematic review and meta-analysis. Diabetes Res Clin Pract pii:S0168-8227(14), 00190-00199. doi: 10.1016/j.diabres.2014.04.007.
-
(2014)
Diabetes Res Clin Pract
, pp. 00190-00199
-
-
Wang, Z.1
Lai, S.T.2
Xie, L.3
Zhao, J.D.4
Ma, N.Y.5
Zhu, J.6
-
81
-
-
80052044405
-
Impact of pancreatic cancer and subsequent resection on glycemic control in diabetic and nondiabetic patients
-
PubMed PMID: 21944519
-
White, M.A., Agle, S.C., Fuhr, H.M., Mehaffey, J.H., Waibel, B.H., and Zervos, E.E. (2011). Impact of pancreatic cancer and subsequent resection on glycemic control in diabetic and nondiabetic patients. Am Surg 77(8), 1032-1037. PubMed PMID: 21944519.
-
(2011)
Am Surg
, vol.77
, Issue.8
, pp. 1032-1037
-
-
White, M.A.1
Agle, S.C.2
Fuhr, H.M.3
Mehaffey, J.H.4
Waibel, B.H.5
Zervos, E.E.6
-
82
-
-
84880538920
-
Hyperglycemia, insulin resistance, impaired pancreatic ß-cell function, and risk of pancreatic cancer
-
Wolpin, B.M., Bao, Y., Qian, Z.R., Wu, C, Kraft, P., Ogino, S., et al. (2013). Hyperglycemia, insulin resistance, impaired pancreatic ß-cell function, and risk of pancreatic cancer. J Natl Cancer Inst 105(14), 1027-1035. doi: 10.1093/jnci/djt123.
-
(2013)
J Natl Cancer Inst
, vol.105
, Issue.14
, pp. 1027-1035
-
-
Wolpin, B.M.1
Bao, Y.2
Qian, Z.R.3
Wu, C.4
Kraft, P.5
Ogino, S.6
-
83
-
-
84908363581
-
Limiting glucose availability with metformin increased reactive oxygen species, decreased cell survival, and promoted apoptosis in human and mouse pancreatic cancer cells
-
abstrnr 5405
-
Yan, G., Freeman, T., and Lanza-Jacoby, S. (2013). Limiting glucose availability with metformin increased reactive oxygen species, decreased cell survival, and promoted apoptosis in human and mouse pancreatic cancer cells. Cancer Res 73(8 Suppl 1), abstrnr 5405. doi: 10.1158/1538-7445.AM2013-5405.
-
(2013)
Cancer Res
, vol.73
, Issue.8
-
-
Yan, G.1
Freeman, T.2
Lanza-Jacoby, S.3
-
84
-
-
84857735480
-
PTEN is a major tumor suppressor in pancreatic ductal adenocarcinoma and regulates an NF-?Bcytokine network
-
Ying, H., Elpek, K.G., Vinjamoori, A., Zimmerman, S.M., Chu, G.C., Yan, H., et al. (2011). PTEN is a major tumor suppressor in pancreatic ductal adenocarcinoma and regulates an NF-?Bcytokine network. Cancer Disc 1(2), 158-169. doi: 10.1158/2159-8290.CD-11-0031.
-
(2011)
Cancer Disc
, vol.1
, Issue.2
, pp. 158-169
-
-
Ying, H.1
Elpek, K.G.2
Vinjamoori, A.3
Zimmerman, S.M.4
Chu, G.C.5
Yan, H.6
-
85
-
-
84898853705
-
Repurposing of metformin and aspirin by targeting AMPK-mTOR and inflammation for pancreatic cancer prevention and treatment
-
Yue, W., Yang, C.S., DiPaola, R.S., and Tan, X.L. (2014). Repurposing of metformin and aspirin by targeting AMPK-mTOR and inflammation for pancreatic cancer prevention and treatment. Cancer Prev Res 7(4), 388-397. doi: 10.1158/1940-6207.CAPR-13-0337.
-
(2014)
Cancer Prev Res
, vol.7
, Issue.4
, pp. 388-397
-
-
Yue, W.1
Yang, C.S.2
DiPaola, R.S.3
Tan, X.L.4
-
86
-
-
84899733576
-
Metformin inhibits the IL-6-induced epithelial-mesenchymal transition and lung adenocarcinoma growth and metastasis
-
Zhao, Z., Cheng, X., Wang, Y., Han, R, Li, L., Xiang, T., et al. (2014). Metformin inhibits the IL-6-induced epithelial-mesenchymal transition and lung adenocarcinoma growth and metastasis. PLoS One 9(4), e95884. doi: 10.1371/journal.pone.0095884.
-
(2014)
PLoS One
, vol.9
, Issue.4
, pp. e95884
-
-
Zhao, Z.1
Cheng, X.2
Wang, Y.3
Han, R.4
Li, L.5
Xiang, T.6
-
87
-
-
84891598818
-
Non-linear dose-response relationship between cigarette smoking and pancreatic cancer risk: evidence from a metaanalysis of 42 observational studies
-
Zou, L., Zhong, R., Shen, N., Chen, W., Zhu, B., Ke, J., et al. (2014). Non-linear dose-response relationship between cigarette smoking and pancreatic cancer risk: evidence from a metaanalysis of 42 observational studies. Eur J Cancer 50(1), 193-203. doi: 10.1016/j.ejca.2013.08.014.
-
(2014)
Eur J Cancer
, vol.50
, Issue.1
, pp. 193-203
-
-
Zou, L.1
Zhong, R.2
Shen, N.3
Chen, W.4
Zhu, B.5
Ke, J.6
|