Adrenomedullin is up-regulated in patients with pancreatic cancer and causes insulin resistance in β cells and mice

Gastroenterology

Volumn 143, Issue 6, 2012, Pages

  Aggarwal, Gaurav ^a   Ramachandran, Vijaya ^d   Javeed, Naureen ^b   Arumugam, Thiruvengadam ^d   Dutta, Shamit ^b   Klee, George G ^c   Klee, Eric W ^c   Smyrk, Thomas C ^c   Bamlet, William ^c   Han, Jing Jing ^c   Rumie Vittar, Natalia B ^c   De Andrade, Mariza ^c   Mukhopadhyay, Debabrata ^b   Petersen, Gloria M ^c   Fernandez Zapico, Martin E ^a,c   Logsdon, Craig D ^d   Chari, Suresh T ^a  

^a MAYO CLINIC   (United States)

^b MAYO GRADUATE SCHOOL   (United States)

^c Mayo Clinic   (United States)

^d UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

Author keywords

Mechanisms; Mouse Model; Pancreas; Tumor

Indexed keywords

ADRENOMEDULLIN; GLUCOSE; INSULIN; MESSENGER RNA;

ADULT; AGED; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CANCER CELL CULTURE; CONTROLLED STUDY; DIABETES MELLITUS; FEMALE; GLUCOSE BLOOD LEVEL; GLUCOSE INTOLERANCE; GLUCOSE TOLERANCE; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; INSULIN RELEASE; INSULIN RESISTANCE; MALE; MICROARRAY ANALYSIS; MOUSE; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; PANCREAS CANCER; PANCREAS ISLET; PRIORITY JOURNAL; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SUPERNATANT; UPREGULATION; XENOGRAFT;

EID: 84869816038     PISSN: 00165085     EISSN: 15280012     Source Type: Journal    
DOI: 10.1053/j.gastro.2012.08.044     Document Type: Article

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