Targeting the extracellular matrix: Matricellular proteins regulate cell-extracellular matrix communication within distinct niches of the intervertebral disc

Matrix Biology

Volumn 37, Issue , 2014, Pages 124-130

  Bedore, Jake ^a   Leask, Andrew ^a   Séguin, Cheryle A ^a  

^a WESTERN UNIVERSITY   (Canada)

Author keywords

Disc degeneration; Extracellular matrix; Intervertebral disc; Matricellular proteins; Microenvironment

Indexed keywords

CELL PROTEIN; CELL SURFACE RECEPTOR; HORMONE; MATRICELLULAR PROTEIN; PROTEINASE; TENASCIN; THROMBOSPONDIN; TRANSCRIPTION FACTOR RUNX2; UNCLASSIFIED DRUG; CCN PROTEIN; CELL ADHESION MOLECULE; OSTEONECTIN; POSTN PROTEIN, HUMAN; SCLEROPROTEIN; SPARC PROTEIN, HUMAN; THROMBOSPONDIN 2;

ANIMAL EXPERIMENT; ARTICLE; CELL COMMUNICATION; CELL FUNCTION; CELL TYPE; EXTRACELLULAR MATRIX; IN VIVO STUDY; INTERVERTEBRAL DISK; MICROENVIRONMENT; MOUSE; NONHUMAN; PHENOTYPE; REGULATORY MECHANISM; CYTOLOGY; DRUG DELIVERY SYSTEM; HUMAN; INTERVERTEBRAL DISC DEGENERATION; METABOLISM; PHYSIOLOGY; PROCEDURES; SIGNAL TRANSDUCTION; TUMOR MICROENVIRONMENT;

CCN INTERCELLULAR SIGNALING PROTEINS; CELL ADHESION MOLECULES; CELL COMMUNICATION; CELLULAR MICROENVIRONMENT; DRUG DELIVERY SYSTEMS; EXTRACELLULAR MATRIX PROTEINS; HUMANS; INTERVERTEBRAL DISC; INTERVERTEBRAL DISC DEGENERATION; OSTEONECTIN; SIGNAL TRANSDUCTION; TENASCIN; THROMBOSPONDINS;

EID: 84908352590     PISSN: 0945053X     EISSN: 15691802     Source Type: Journal    
DOI: 10.1016/j.matbio.2014.05.005     Document Type: Review

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