-
1
-
-
43049088843
-
Stem and progenitor cell-mediated tumor selective gene therapy
-
Aboody KS, Najbauer J, Danks MK. 2008. Stem and progenitor cell-mediated tumor selective gene therapy. Gene Ther 15: 739-752.
-
(2008)
Gene Ther
, vol.15
, pp. 739-752
-
-
Aboody, K.S.1
Najbauer, J.2
Danks, M.K.3
-
2
-
-
0345276632
-
Essential role of endothelial nitric oxide synthase for mobilization of stem and progenitor cells
-
Aicher A, Heeschen C, Mildner-Rihm C, Urbich C, Ihling C, Technau-Ihling K, Zeiher AM, Dimmeler S. 2003. Essential role of endothelial nitric oxide synthase for mobilization of stem and progenitor cells. Nat Med 9: 1370-1376.
-
(2003)
Nat Med
, vol.9
, pp. 1370-1376
-
-
Aicher, A.1
Heeschen, C.2
Mildner-Rihm, C.3
Urbich, C.4
Ihling, C.5
Technau-Ihling, K.6
Zeiher, A.M.7
Dimmeler, S.8
-
3
-
-
34548219477
-
ABT-510, a modified type 1 repeat peptide of thrombospondin, inhibits malignant glioma growth in vivo by inhibiting angiogenesis
-
Anderson JC, Grammer JR, Wang W, Nabors LB, Henkin J, Stewart JE Jr., GladsonCL. 2007. ABT-510, a modified type 1 repeat peptide of thrombospondin, inhibits malignant glioma growth in vivo by inhibiting angiogenesis. Cancer Biol Ther 6: 454-462.
-
(2007)
Cancer Biol Ther
, vol.6
, pp. 454-462
-
-
Anderson, J.C.1
Grammer, J.R.2
Wang, W.3
Nabors, L.B.4
Henkin, J.5
Stewart Jr., J.E.6
Gladson, C.L.7
-
5
-
-
0025171017
-
Specific inhibition of endothelial cell proliferation by thrombospondin
-
Bagavandoss P, Wilks JW. 1990. Specific inhibition of endothelial cell proliferation by thrombospondin. Biochem Biophys Res Commun 170: 867-872.
-
(1990)
Biochem Biophys Res Commun
, vol.170
, pp. 867-872
-
-
Bagavandoss, P.1
Wilks, J.W.2
-
6
-
-
57149111052
-
Randomized, phase II study of the thrombospondin-1-mimetic angiogenesis inhibitor ABT-510 in patients with advanced soft tissue sarcoma
-
Baker LH, Rowinsky EK, Mendelson D, Humerickhouse RA, Knight RA, Qian J, Carr RA, Gordon GB, Demetri GD. 2008. Randomized, phase II study of the thrombospondin-1-mimetic angiogenesis inhibitor ABT-510 in patients with advanced soft tissue sarcoma. J Clin Oncol 26: 5583-5588.
-
(2008)
J Clin Oncol
, vol.26
, pp. 5583-5588
-
-
Baker, L.H.1
Rowinsky, E.K.2
Mendelson, D.3
Humerickhouse, R.A.4
Knight, R.A.5
Qian, J.6
Carr, R.A.7
Gordon, G.B.8
Demetri, G.D.9
-
7
-
-
0034644748
-
Thrombospondin type 1 repeats interact with matrix metalloproteinase 2. Regulation of metalloproteinase activity
-
Bein K, Simons M. 2000. Thrombospondin type 1 repeats interact with matrix metalloproteinase 2. Regulation of metalloproteinase activity. J Biol Chem 275: 32167-32173.
-
(2000)
J Biol Chem
, vol.275
, pp. 32167-32173
-
-
Bein, K.1
Simons, M.2
-
8
-
-
0027745333
-
Thrombospondin and in vivo angiogenesis induced by basic fibroblast growth factor or lipopolysaccharide
-
BenEzra D, Griffin BW, Maftzir G, Aharonov O. 1993. Thrombospondin and in vivo angiogenesis induced by basic fibroblast growth factor or lipopolysaccharide. Invest Ophthalmol Vis Sci 34: 3601-3608.
-
(1993)
Invest Ophthalmol Vis Sci
, vol.34
, pp. 3601-3608
-
-
BenEzra, D.1
Griffin, B.W.2
Maftzir, G.3
Aharonov, O.4
-
9
-
-
0242331613
-
Thrombospondin 1, a mediator of the antiangiogenic effects of low-dose metronomic chemotherapy
-
Bocci G, Francia G, Man S, Lawler J, Kerbel RS. 2003. Thrombospondin 1, a mediator of the antiangiogenic effects of low-dose metronomic chemotherapy. Proc Natl Acad Sci 100: 12917-12922.
-
(2003)
Proc Natl Acad Sci
, vol.100
, pp. 12917-12922
-
-
Bocci, G.1
Francia, G.2
Man, S.3
Lawler, J.4
Kerbel, R.S.5
-
10
-
-
0034032882
-
Antiangiogenic scheduling of chemotherapy improves efficacy against experimental drug-resistant cancer
-
Browder T, Butterfield CE, Kraling BM, Shi B, Marshall B, O'Reilly MS, Folkman J. 2000. Antiangiogenic scheduling of chemotherapy improves efficacy against experimental drug-resistant cancer. Cancer Res 60: 1878-1886.
-
(2000)
Cancer Res
, vol.60
, pp. 1878-1886
-
-
Browder, T.1
Butterfield, C.E.2
Kraling, B.M.3
Shi, B.4
Marshall, B.5
O'Reilly, M.S.6
Folkman, J.7
-
11
-
-
4744352055
-
1 integrin binding sites in the type 1 and type 2 repeats of thrombospondin-1
-
1 integrin binding sites in the type 1 and type 2 repeats of thrombospondin-1. J Biol Chem 279: 41734-41743.
-
(2004)
J Biol Chem
, vol.279
, pp. 41734-41743
-
-
Calzada, M.J.1
Annis, D.S.2
Zeng, B.3
Marcinkiewicz, C.4
Banas, B.5
Lawler, J.6
Mosher, D.F.7
Roberts, D.D.8
-
12
-
-
77949621084
-
The thrombospondin-1 mimetic ABT-510 increases the uptake and effectiveness of cisplatin and paclitaxel in a mouse model of epithelial ovarian cancer
-
Campbell NE, Greenaway J, Henkin J, Moorehead RA, Petrik J. 2010. The thrombospondin-1 mimetic ABT-510 increases the uptake and effectiveness of cisplatin and paclitaxel in a mouse model of epithelial ovarian cancer. Neoplasia 12: 275-283.
-
(2010)
Neoplasia
, vol.12
, pp. 275-283
-
-
Campbell, N.E.1
Greenaway, J.2
Henkin, J.3
Moorehead, R.A.4
Petrik, J.5
-
13
-
-
0033734494
-
The cell biology of thrombospondin-1
-
Chen H, Herndon ME, Lawler J. 2000. The cell biology of thrombospondin-1. Matrix Biol 19: 597-614.
-
(2000)
Matrix Biol
, vol.19
, pp. 597-614
-
-
Chen, H.1
Herndon, M.E.2
Lawler, J.3
-
14
-
-
67649099677
-
Antiangiogenic strategies for treatment of malignant gliomas
-
Chi AS, Norden AD, Wen PY. 2009a. Antiangiogenic strategies for treatment of malignant gliomas. Neurotherapeutics 6: 513-526.
-
(2009)
Neurotherapeutics
, vol.6
, pp. 513-526
-
-
Chi, A.S.1
Norden, A.D.2
Wen, P.Y.3
-
16
-
-
77950551541
-
Non-peptidic thrombospondin-1 mimics as fibroblast growth factor-2 inhibitors: An integrated strategy for the development of new antiangiogenic compounds
-
Colombo G, Margosio B, Ragona L, Neves M, Bonifacio S, Annis DS, StravalaciM, Tomaselli S, Giavazzi R, Rusnati M, et al. 2010. Non-peptidic thrombospondin-1 mimics as fibroblast growth factor-2 inhibitors: An integrated strategy for the development of new antiangiogenic compounds. J Biol Chem 285: 8733-8742.
-
(2010)
J Biol Chem
, vol.285
, pp. 8733-8742
-
-
Colombo, G.1
Margosio, B.2
Ragona, L.3
Neves, M.4
Bonifacio, S.5
Annis, D.S.6
Stravalaci, M.7
Tomaselli, S.8
Giavazzi, R.9
Rusnati, M.10
-
17
-
-
0030833817
-
CD36 mediates the in vitro inhibitory effects of thrombospondin-1 on endothelial cells
-
Dawson DW, Pearce SF, Zhong R, Silverstein RL, Frazier WA, Bouck NP. 1997. CD36 mediates the in vitro inhibitory effects of thrombospondin-1 on endothelial cells. J Cell Biol 138: 707-717.
-
(1997)
J Cell Biol
, vol.138
, pp. 707-717
-
-
Dawson, D.W.1
Pearce, S.F.2
Zhong, R.3
Silverstein, R.L.4
Frazier, W.A.5
Bouck, N.P.6
-
18
-
-
0033027727
-
Three distinct D-amino acid substitutions confer potent antiangiogenic activity on an inactive peptide derived from a thrombospondin-1 type 1 repeat
-
Dawson DW, Volpert OV, Pearce SF, Schneider AJ, Silverstein RL, Henkin J, Bouck NP. 1999. Three distinct D-amino acid substitutions confer potent antiangiogenic activity on an inactive peptide derived from a thrombospondin-1 type 1 repeat. Mol Pharmacol 55: 332-338.
-
(1999)
Mol Pharmacol
, vol.55
, pp. 332-338
-
-
Dawson, D.W.1
Volpert, O.V.2
Pearce, S.F.3
Schneider, A.J.4
Silverstein, R.L.5
Henkin, J.6
Bouck, N.P.7
-
19
-
-
58149151390
-
Circulating endothelial cells, bone marrow-derived endothelial progenitor cells and proangiogenic hematopoietic cells in cancer: From biology to therapy
-
Dome B, Timar J, Ladanyi A, Paku S, Renyi-Vamos F, Klepetko W, Lang G, Dome P, Bogos K, Tovari J. 2009. Circulating endothelial cells, bone marrow-derived endothelial progenitor cells and proangiogenic hematopoietic cells in cancer: From biology to therapy. Crit Rev Oncol Hematol 69: 108-124.
-
(2009)
Crit Rev Oncol Hematol
, vol.69
, pp. 108-124
-
-
Dome, B.1
Timar, J.2
Ladanyi, A.3
Paku, S.4
Renyi-Vamos, F.5
Klepetko, W.6
Lang, G.7
Dome, P.8
Bogos, K.9
Tovari, J.10
-
20
-
-
1642619061
-
Role of eNOS in neovascularization: NO for endothelial progenitor cells
-
Duda DG, Fukumura D, Jain RK. 2004. Role of eNOS in neovascularization: NO for endothelial progenitor cells. Trends Mol Med 10: 143-145.
-
(2004)
Trends Mol Med
, vol.10
, pp. 143-145
-
-
Duda, D.G.1
Fukumura, D.2
Jain, R.K.3
-
21
-
-
34250731849
-
Life history of eNOS: Partners and pathways
-
Dudzinski DM, Michel T. 2007. Life history of eNOS: Partners and pathways. Cardiovasc Res 75: 247-260.
-
(2007)
Cardiovasc Res
, vol.75
, pp. 247-260
-
-
Dudzinski, D.M.1
Michel, T.2
-
22
-
-
36749060830
-
Phase 2 study of ABT-510 in patients with previously untreated advanced renal cell carcinoma
-
Ebbinghaus S, Hussain M, Tannir N, Gordon M, Desai AA, Knight RA, Humerickhouse RA, Qian J, Gordon GB, Figlin R. 2007. Phase 2 study of ABT-510 in patients with previously untreated advanced renal cell carcinoma. Clin Cancer Res 13: 6689-6695.
-
(2007)
Clin Cancer Res
, vol.13
, pp. 6689-6695
-
-
Ebbinghaus, S.1
Hussain, M.2
Tannir, N.3
Gordon, M.4
Desai, A.A.5
Knight, R.A.6
Humerickhouse, R.A.7
Qian, J.8
Gordon, G.B.9
Figlin, R.10
-
23
-
-
0036070105
-
2-terminal heparin-binding domain of the adhesive glycoprotein, thrombospondin-1, promotes endothelial tube formation and cell survival: A possible role for syndecan-4 proteoglycan
-
2-terminal heparin-binding domain of the adhesive glycoprotein, thrombospondin-1, promotes endothelial tube formation and cell survival: A possible role for syndecan-4 proteoglycan. Matrix Biol 21: 311-324.
-
(2002)
Matrix Biol
, vol.21
, pp. 311-324
-
-
Ferrari do Outeiro-Bernstein, M.A.1
Nunes, S.S.2
Andrade, A.C.3
Alves, T.R.4
Legrand, C.5
Morandi, V.6
-
24
-
-
85013312416
-
Tumor angiogenesis: Therapeutic implications
-
Folkman J. 1971. Tumor angiogenesis: Therapeutic implications. N Engl J Med 285: 1182-1186.
-
(1971)
N Engl J Med
, vol.285
, pp. 1182-1186
-
-
Folkman, J.1
-
25
-
-
0035956947
-
Predominant role of endothelial nitric oxide synthase in vascular endothelial growth factor-induced angiogenesis and vascular permeability
-
Fukumura D, Gohongi T, Kadambi A, Izumi Y, Ang J, Yun CO, Buerk DG, HuangPL, Jain RK. 2001. Predominant role of endothelial nitric oxide synthase in vascular endothelial growth factor-induced angiogenesis and vascular permeability. Proc Natl Acad Sci 98: 2604-2609.
-
(2001)
Proc Natl Acad Sci
, vol.98
, pp. 2604-2609
-
-
Fukumura, D.1
Gohongi, T.2
Kadambi, A.3
Izumi, Y.4
Ang, J.5
Yun, C.O.6
Buerk, D.G.7
Huang, P.L.8
Jain, R.K.9
-
26
-
-
0030032579
-
Integrin-associated protein is a receptor for the C-terminal domain of thrombospondin
-
Gao AG, Lindberg FP, Finn MB, Blystone SD, Brown EJ, Frazier WA. 1996. Integrin-associated protein is a receptor for the C-terminal domain of thrombospondin. J Biol Chem 271: 21-24.
-
(1996)
J Biol Chem
, vol.271
, pp. 21-24
-
-
Gao, A.G.1
Lindberg, F.P.2
Finn, M.B.3
Blystone, S.D.4
Brown, E.J.5
Frazier, W.A.6
-
27
-
-
0025147371
-
A tumor suppressor-dependent inhibitor of angiogenesis is immunologically and functionally indistinguishable from a fragment of thrombospondin
-
Good DJ, Polverini PJ, Rastinejad F, Le Beau MM, Lemons RS, Frazier WA, BouckNP. 1990. A tumor suppressor-dependent inhibitor of angiogenesis is immunologically and functionally indistinguishable from a fragment of thrombospondin. Proc Natl Acad Sci 87: 6624-6628.
-
(1990)
Proc Natl Acad Sci
, vol.87
, pp. 6624-6628
-
-
Good, D.J.1
Polverini, P.J.2
Rastinejad, F.3
Le Beau, M.M.4
Lemons, R.S.5
Frazier, W.A.6
Bouck, N.P.7
-
28
-
-
57649139197
-
A phase 1 trial of 2 dose schedules of ABT-510, an antiangiogenic, thrombospondin-1-mimetic peptide, in patients with advanced cancer
-
Gordon MS, Mendelson D, Carr R, Knight RA, Humerickhouse RA, Iannone M, Stopeck AT. 2008. A phase 1 trial of 2 dose schedules of ABT-510, an antiangiogenic, thrombospondin-1-mimetic peptide, in patients with advanced cancer. Cancer 113: 3420-3429.
-
(2008)
Cancer
, vol.113
, pp. 3420-3429
-
-
Gordon, M.S.1
Mendelson, D.2
Carr, R.3
Knight, R.A.4
Humerickhouse, R.A.5
Iannone, M.6
Stopeck, A.T.7
-
29
-
-
33846598411
-
Thrombospondin-1 inhibits VEGF levels in the ovary directly by binding and internalization via the low density lipoprotein receptor-related protein-1 (LRP-1)
-
Greenaway J, Lawler J, Moorehead R, Bornstein P, Lamarre J, Petrik J. 2007. Thrombospondin-1 inhibits VEGF levels in the ovary directly by binding and internalization via the low density lipoprotein receptor-related protein-1 (LRP-1). J Cell Physiol 210: 807-818.
-
(2007)
J Cell Physiol
, vol.210
, pp. 807-818
-
-
Greenaway, J.1
Lawler, J.2
Moorehead, R.3
Bornstein, P.4
Lamarre, J.5
Petrik, J.6
-
30
-
-
58149521990
-
ABT-510 induces tumor cell apoptosis and inhibits ovarian tumor growth in an orthotopic, syngeneic model of epithelial ovarian cancer
-
Greenaway J, Henkin J, Lawler J, Moorehead R, Petrik J. 2009. ABT-510 induces tumor cell apoptosis and inhibits ovarian tumor growth in an orthotopic, syngeneic model of epithelial ovarian cancer. Mol Cancer Ther 8: 64-74.
-
(2009)
Mol Cancer Ther
, vol.8
, pp. 64-74
-
-
Greenaway, J.1
Henkin, J.2
Lawler, J.3
Moorehead, R.4
Petrik, J.5
-
31
-
-
0030874871
-
Antiproliferative and antitumor activities of D-reverse peptides derived from the second type-1 repeat of thrombospondin-1
-
Guo NH, Krutzsch HC, Inman JK, Shannon CS, Roberts DD. 1997. Antiproliferative and antitumor activities of D-reverse peptides derived from the second type-1 repeat of thrombospondin-1. J Pept Res 50: 210-221.
-
(1997)
J Pept Res
, vol.50
, pp. 210-221
-
-
Guo, N.H.1
Krutzsch, H.C.2
Inman, J.K.3
Shannon, C.S.4
Roberts, D.D.5
-
32
-
-
0009849965
-
Binding and displacement of vascular endothelial growth factor (VEGF) by thrombospondin: Effect on human microvascular endothelial cell proliferation and angiogenesis
-
Gupta K, Gupta P, Wild R, Ramakrishnan S, Hebbel RP. 1999. Binding and displacement of vascular endothelial growth factor (VEGF) by thrombospondin: Effect on human microvascular endothelial cell proliferation and angiogenesis. Angiogenesis 3: 147-158.
-
(1999)
Angiogenesis
, vol.3
, pp. 147-158
-
-
Gupta, K.1
Gupta, P.2
Wild, R.3
Ramakrishnan, S.4
Hebbel, R.P.5
-
33
-
-
0030576517
-
Patterns and emerging mechanisms of the angiogenic switch during tumorigenesis
-
Hanahan D, Folkman J. 1996. Patterns and emerging mechanisms of the angiogenic switch during tumorigenesis. Cell 86: 353-364.
-
(1996)
Cell
, vol.86
, pp. 353-364
-
-
Hanahan, D.1
Folkman, J.2
-
34
-
-
20944443196
-
Thrombospondin-1 mimetic peptide inhibitors of angiogenesis and tumor growth: Design, synthesis, and optimization of pharmacokinetics and biological activities
-
Haviv F, Bradley MF, Kalvin DM, Schneider AJ, Davidson DJ, Majest SM, McKayLM, Haskell CJ, Bell RL, Nguyen B, et al. 2005. Thrombospondin-1 mimetic peptide inhibitors of angiogenesis and tumor growth: Design, synthesis, and optimization of pharmacokinetics and biological activities. J Med Chem 48: 2838-2846.
-
(2005)
J Med Chem
, vol.48
, pp. 2838-2846
-
-
Haviv, F.1
Bradley, M.F.2
Kalvin, D.M.3
Schneider, A.J.4
Davidson, D.J.5
Majest, S.M.6
McKay, L.M.7
Haskell, C.J.8
Bell, R.L.9
Nguyen, B.10
-
35
-
-
1642303371
-
Heparin affin regulatory peptide binds to vascular endothelial growth factor (VEGF) and inhibits VEGF-induced angiogenesis
-
Heroult M, Bernard-Pierrot I, Delbe J, Hamma-Kourbali Y, Katsoris P, BarritaultD, Papadimitriou E, Plouet J, Courty J. 2004. Heparin affin regulatory peptide binds to vascular endothelial growth factor (VEGF) and inhibits VEGF-induced angiogenesis. Oncogene 23: 1745-1753.
-
(2004)
Oncogene
, vol.23
, pp. 1745-1753
-
-
Heroult, M.1
Bernard-Pierrot, I.2
Delbe, J.3
Hamma-Kourbali, Y.4
Katsoris, P.5
Barritault, D.6
Papadimitriou, E.7
Plouet, J.8
Courty, J.9
-
36
-
-
24644508961
-
Phase I safety, pharmacokinetic, and pharmacodynamic study of the thrombospondin-1-mimetic angiogenesis inhibitor ABT-510 in patients with advanced cancer
-
Hoekstra R, de Vos FY, Eskens FA, Gietema JA, van der Gaast A, Groen HJ, Knight RA, Carr RA, Humerickhouse RA, Verweij J, et al. 2005. Phase I safety, pharmacokinetic, and pharmacodynamic study of the thrombospondin-1-mimetic angiogenesis inhibitor ABT-510 in patients with advanced cancer. J Clin Oncol 23: 5188-5197.
-
(2005)
J Clin Oncol
, vol.23
, pp. 5188-5197
-
-
Hoekstra, R.1
de Vos, F.Y.2
Eskens, F.A.3
Gietema, J.A.4
van der Gaast, A.5
Groen, H.J.6
Knight, R.A.7
Carr, R.A.8
Humerickhouse, R.A.9
Verweij, J.10
-
37
-
-
32444431721
-
Phase I study of the thrombospondin-1-mimetic angiogenesis inhibitor ABT-510 with 5-fluorouracil and leucovorin: A safe combination
-
Hoekstra R, de Vos FY, Eskens FA, de Vries EG, Uges DR, Knight R, Carr RA, Humerickhouse R, Verweij J, Gietema JA. 2006. Phase I study of the thrombospondin-1-mimetic angiogenesis inhibitor ABT-510 with 5-fluorouracil and leucovorin: A safe combination. Eur J Cancer 42: 467-472.
-
(2006)
Eur J Cancer
, vol.42
, pp. 467-472
-
-
Hoekstra, R.1
de Vos, F.Y.2
Eskens, F.A.3
de Vries, E.G.4
Uges, D.R.5
Knight, R.6
Carr, R.A.7
Humerickhouse, R.8
Verweij, J.9
Gietema, J.A.10
-
38
-
-
70849099495
-
The extracellular matrix: Not just pretty fibrils
-
Hynes RO. 2009. The extracellular matrix: Not just pretty fibrils. Science 326: 1216-1219.
-
(2009)
Science
, vol.326
, pp. 1216-1219
-
-
Hynes, R.O.1
-
39
-
-
0036481769
-
Connective tissue growth factor binds vascular endothelial growth factor (VEGF) and inhibits VEGF-induced angiogenesis
-
Inoki I, Shiomi T, Hashimoto G, Enomoto H, Nakamura H, Makino K, Ikeda E, Takata S, Kobayashi K, Okada Y. 2002. Connective tissue growth factor binds vascular endothelial growth factor (VEGF) and inhibits VEGF-induced angiogenesis. FASEB J 16: 219-221.
-
(2002)
FASEB J
, vol.16
, pp. 219-221
-
-
Inoki, I.1
Shiomi, T.2
Hashimoto, G.3
Enomoto, H.4
Nakamura, H.5
Makino, K.6
Ikeda, E.7
Takata, S.8
Kobayashi, K.9
Okada, Y.10
-
40
-
-
65849137401
-
Regulation of thrombospondin1 by extracellular proteases
-
Iruela-Arispe ML. 2008. Regulation of thrombospondin1 by extracellular proteases. Curr Drug Targets 9: 863-868.
-
(2008)
Curr Drug Targets
, vol.9
, pp. 863-868
-
-
Iruela-Arispe, M.L.1
-
41
-
-
0033613226
-
Inhibition of angiogenesis by thrombospondin-1 is mediated by 2 independent regions within the type 1 repeats
-
Iruela-Arispe ML, Lombardo M, Krutzsch HC, Lawler J, Roberts DD. 1999. Inhibition of angiogenesis by thrombospondin-1 is mediated by 2 independent regions within the type 1 repeats. Circulation 100: 1423-1431.
-
(1999)
Circulation
, vol.100
, pp. 1423-1431
-
-
Iruela-Arispe, M.L.1
Lombardo, M.2
Krutzsch, H.C.3
Lawler, J.4
Roberts, D.D.5
-
42
-
-
24944572974
-
Thrombospondin-1 inhibits endothelial cell responses to nitric oxide in a cGMP-dependent manner
-
Isenberg JS, Ridnour LA, Perruccio EM, Espey MG, Wink DA, Roberts DD. 2005. Thrombospondin-1 inhibits endothelial cell responses to nitric oxide in a cGMP-dependent manner. Proc Natl Acad Sci 102: 13141-13146.
-
(2005)
Proc Natl Acad Sci
, vol.102
, pp. 13141-13146
-
-
Isenberg, J.S.1
Ridnour, L.A.2
Perruccio, E.M.3
Espey, M.G.4
Wink, D.A.5
Roberts, D.D.6
-
43
-
-
33748747969
-
CD47 is necessary for inhibition of nitric oxide-stimulated vascular cell responses by thrombospondin-1
-
Isenberg JS, Ridnour LA, Dimitry J, Frazier WA, Wink DA, Roberts DD. 2006. CD47 is necessary for inhibition of nitric oxide-stimulated vascular cell responses by thrombospondin-1. J Biol Chem 281: 26069-26080.
-
(2006)
J Biol Chem
, vol.281
, pp. 26069-26080
-
-
Isenberg, J.S.1
Ridnour, L.A.2
Dimitry, J.3
Frazier, W.A.4
Wink, D.A.5
Roberts, D.D.6
-
44
-
-
34447508335
-
Thrombospondin-1 inhibits nitric oxide signaling via CD36 by inhibiting myristic acid uptake
-
Isenberg JS, Jia Y, Fukuyama J, Switzer CH, Wink DA, Roberts DD. 2007. Thrombospondin-1 inhibits nitric oxide signaling via CD36 by inhibiting myristic acid uptake. J Biol Chem 282: 15404-15415.
-
(2007)
J Biol Chem
, vol.282
, pp. 15404-15415
-
-
Isenberg, J.S.1
Jia, Y.2
Fukuyama, J.3
Switzer, C.H.4
Wink, D.A.5
Roberts, D.D.6
-
45
-
-
37549059962
-
Blockade of thrombospondin-1-CD47 interactions prevents necrosis of full thickness skin grafts
-
Isenberg JS, Pappan LK, Romeo MJ, Abu-Asab M, Tsokos M, Wink DA, FrazierWA, Roberts DD. 2008. Blockade of thrombospondin-1-CD47 interactions prevents necrosis of full thickness skin grafts. Ann Surg 247: 180-190.
-
(2008)
Ann Surg
, vol.247
, pp. 180-190
-
-
Isenberg, J.S.1
Pappan, L.K.2
Romeo, M.J.3
Abu-Asab, M.4
Tsokos, M.5
Wink, D.A.6
Frazier, W.A.7
Roberts, D.D.8
-
46
-
-
59449091909
-
Differential interactions of thrombospondin-1,-2, and-4 with CD47 and effects on cGMP signaling and ischemic injury responses
-
Isenberg JS, Annis DS, Pendrak ML, Ptaszynska M, Frazier WA, Mosher DF, Roberts DD. 2009a. Differential interactions of thrombospondin-1,-2, and-4 with CD47 and effects on cGMP signaling and ischemic injury responses. J Biol Chemo 284: 1116-1125.
-
(2009)
J Biol Chemo
, vol.284
, pp. 1116-1125
-
-
Isenberg, J.S.1
Annis, D.S.2
Pendrak, M.L.3
Ptaszynska, M.4
Frazier, W.A.5
Mosher, D.F.6
Roberts, D.D.7
-
47
-
-
60749091126
-
Regulation of nitric oxide signaling by thrombospondin 1: Implications for anti-angiogenic therapies
-
Isenberg JS, Martin-Manso G, Maxhimer JB, Roberts DD. 2009b. Regulation of nitric oxide signaling by thrombospondin 1: Implications for anti-angiogenic therapies. Nat Rev Cancer 9: 182-194.
-
(2009)
Nat Rev Cancer
, vol.9
, pp. 182-194
-
-
Isenberg, J.S.1
Martin-Manso, G.2
Maxhimer, J.B.3
Roberts, D.D.4
-
48
-
-
34447635695
-
Angiogenesis inhibitor therapies: Focus on kidney toxicity and hypertension
-
Izzedine H, Rixe O, Billemont B, Baumelou A, Deray G. 2007. Angiogenesis inhibitor therapies: Focus on kidney toxicity and hypertension. Am J Kidney Dis 50: 203-218.
-
(2007)
Am J Kidney Dis
, vol.50
, pp. 203-218
-
-
Izzedine, H.1
Rixe, O.2
Billemont, B.3
Baumelou, A.4
Deray, G.5
-
49
-
-
0342445431
-
Signals leading to apoptosis-dependent inhibition of neovascularization by thrombospondin-1
-
Jimenez B, Volpert OV, Crawford SE, Febbraio M, Silverstein RL, Bouck N. 2000. Signals leading to apoptosis-dependent inhibition of neovascularization by thrombospondin-1. Nat Med 6: 41-48.
-
(2000)
Nat Med
, vol.6
, pp. 41-48
-
-
Jimenez, B.1
Volpert, O.V.2
Crawford, S.E.3
Febbraio, M.4
Silverstein, R.L.5
Bouck, N.6
-
50
-
-
0035821779
-
c-Jun N-terminal kinase activation is required for the inhibition of neovascularization by thrombospondin-1
-
Jimenez B, Volpert OV, Reiher F, Chang L, Munoz A, Karin M, Bouck N. 2001. c-Jun N-terminal kinase activation is required for the inhibition of neovascularization by thrombospondin-1. Oncogene 20: 3443-3448.
-
(2001)
Oncogene
, vol.20
, pp. 3443-3448
-
-
Jimenez, B.1
Volpert, O.V.2
Reiher, F.3
Chang, L.4
Munoz, A.5
Karin, M.6
Bouck, N.7
-
51
-
-
0037219173
-
Brain angiogenesis inhibitor 1 is differentially expressed in normal brain and glioblastoma independently of p53 expression
-
Kaur B, Brat DJ, Calkins CC, Van Meir EG. 2003. Brain angiogenesis inhibitor 1 is differentially expressed in normal brain and glioblastoma independently of p53 expression. Am J Pathol 162: 19-27.
-
(2003)
Am J Pathol
, vol.162
, pp. 19-27
-
-
Kaur, B.1
Brat, D.J.2
Calkins, C.C.3
Van Meir, E.G.4
-
52
-
-
0035887379
-
Continuous administration of endostatin by intraperitoneally implanted osmotic pump improves the efficacy and potency of therapy in a mouse xenograft tumor model
-
Kisker O, Becker CM, Prox D, Fannon M, D'Amato R, Flynn E, Fogler WE, SimBK, Allred EN, Pirie-Shepherd, et al. 2001. Continuous administration of endostatin by intraperitoneally implanted osmotic pump improves the efficacy and potency of therapy in a mouse xenograft tumor model. Cancer Res 61: 7669-7674.
-
(2001)
Cancer Res
, vol.61
, pp. 7669-7674
-
-
Kisker, O.1
Becker, C.M.2
Prox, D.3
Fannon, M.4
D'Amato, R.5
Flynn, E.6
Fogler, W.E.7
Sim, B.K.8
Allred, E.N.9
Pirie-Shepherd10
-
53
-
-
79959706654
-
CD36-mediated activation of endothelial cell apoptosis by an N-terminal recombinant fragment of thrombospondin-2 inhibits breast cancer growth and metastasis in vivo
-
Koch M, Hussein F, Woeste A, Grundker C, Frontzek K, Emons G, HawighorstT. 2011. CD36-mediated activation of endothelial cell apoptosis by an N-terminal recombinant fragment of thrombospondin-2 inhibits breast cancer growth and metastasis in vivo. Breast Cancer Res Treat 128: 337-346.
-
(2011)
Breast Cancer Res Treat
, vol.128
, pp. 337-346
-
-
Koch, M.1
Hussein, F.2
Woeste, A.3
Grundker, C.4
Frontzek, K.5
Emons, G.6
Hawighorst, T.7
-
54
-
-
0018253429
-
Isolation and characterization of a high molecular weight glycoprotein from human blood platelets
-
Lawler JW, Slayter HS, Coligan JE. 1978. Isolation and characterization of a high molecular weight glycoprotein from human blood platelets. J Biol Chem 253: 8609-8616.
-
(1978)
J Biol Chem
, vol.253
, pp. 8609-8616
-
-
Lawler, J.W.1
Slayter, H.S.2
Coligan, J.E.3
-
55
-
-
63849185760
-
Enhanced angiogenesis and reduced contraction in thrombospondin-2-null wounds is associated with increased levels of matrix metalloproteinases-2 and-9, and soluble VEGF
-
Maclauchlan S, Skokos EA, Agah A, Zeng J, Tian W, Davidson JM, Bornstein P, Kyriakides TR. 2009. Enhanced angiogenesis and reduced contraction in thrombospondin-2-null wounds is associated with increased levels of matrix metalloproteinases-2 and-9, and soluble VEGF. J Histochem Cytochem 57: 301-313.
-
(2009)
J Histochem Cytochem
, vol.57
, pp. 301-313
-
-
McLauchlan, S.1
Skokos, E.A.2
Agah, A.3
Zeng, J.4
Tian, W.5
Davidson, J.M.6
Bornstein, P.7
Kyriakides, T.R.8
-
56
-
-
34249990658
-
A phase II study of ABT-510 (thrombospondin-1 analog) for the treatment of metastatic melanoma
-
Markovic SN, Suman VJ, Rao RA, Ingle JN, Kaur JS, Erickson LA, Pitot HC, Croghan GA, McWilliams RR, Merchan J, et al. 2007. A phase II study of ABT-510 (thrombospondin-1 analog) for the treatment of metastatic melanoma. Am J Clin Oncol 30: 303-309.
-
(2007)
Am J Clin Oncol
, vol.30
, pp. 303-309
-
-
Markovic, S.N.1
Suman, V.J.2
Rao, R.A.3
Ingle, J.N.4
Kaur, J.S.5
Erickson, L.A.6
Pitot, H.C.7
Croghan, G.A.8
McWilliams, R.R.9
Merchan, J.10
-
57
-
-
0035503689
-
Thrombospondin-1 type 1 repeat recombinant proteins inhibit tumor growth through transforming growth factor-β-dependent and-independent mechanisms
-
Miao WM, Seng WL, Duquette M, Lawler P, Laus C, Lawler J. 2001. Thrombospondin-1 type 1 repeat recombinant proteins inhibit tumor growth through transforming growth factor-β-dependent and-independent mechanisms. Cancer Res 61: 7830-7839.
-
(2001)
Cancer Res
, vol.61
, pp. 7830-7839
-
-
Miao, W.M.1
Seng, W.L.2
Duquette, M.3
Lawler, P.4
Laus, C.5
Lawler, J.6
-
58
-
-
21644489952
-
Nitric oxide, VEGF, and VEGFR-2: Interactions in activity-induced angiogenesis in rat skeletal muscle
-
Milkiewicz M, Hudlicka O, Brown MD, Silgram H. 2005. Nitric oxide, VEGF, and VEGFR-2: Interactions in activity-induced angiogenesis in rat skeletal muscle. Am J Physiol Heart Circ Physiol 289: H336-H343.
-
(2005)
Am J Physiol Heart Circ Physiol
, vol.289
-
-
Milkiewicz, M.1
Hudlicka, O.2
Brown, M.D.3
Silgram, H.4
-
59
-
-
65849274263
-
Thrombospondin and apoptosis: Molecular mechanisms and use for design of complementation treatments
-
Mirochnik Y, Kwiatek A, Volpert OV. 2008. Thrombospondin and apoptosis: Molecular mechanisms and use for design of complementation treatments. Curr Drug Targets 9: 851-862.
-
(2008)
Curr Drug Targets
, vol.9
, pp. 851-862
-
-
Mirochnik, Y.1
Kwiatek, A.2
Volpert, O.V.3
-
60
-
-
0037277578
-
Role of nitric oxide in the modulation of angiogenesis
-
Morbidelli L, Donnini S, Ziche M. 2003. Role of nitric oxide in the modulation of angiogenesis. Curr Pharm Des 9: 521-530.
-
(2003)
Curr Pharm Des
, vol.9
, pp. 521-530
-
-
Morbidelli, L.1
Donnini, S.2
Ziche, M.3
-
61
-
-
0032102292
-
Nitric oxide synthase modulates angiogenesis in response to tissue ischemia
-
Murohara T, Asahara T, Silver M, Bauters C, Masuda H, Kalka C, Kearney M, Chen D, Symes JF, Fishman MC, et al. 1998. Nitric oxide synthase modulates angiogenesis in response to tissue ischemia. J Clin Invest 101: 2567-2578.
-
(1998)
J Clin Invest
, vol.101
, pp. 2567-2578
-
-
Murohara, T.1
Asahara, T.2
Silver, M.3
Bauters, C.4
Masuda, H.5
Kalka, C.6
Kearney, M.7
Chen, D.8
Symes, J.F.9
Fishman, M.C.10
-
62
-
-
77749332056
-
A phase 1 trial of ABT-510 concurrent with standard chemoradiation for patients with newly diagnosed glioblastoma
-
Nabors LB, Fiveash JB, Markert JM, Kekan MS, Gillespie GY, Huang Z, JohnsonMJ, Meleth S, Kuo H, Gladson CL, et al. 2010. A phase 1 trial of ABT-510 concurrent with standard chemoradiation for patients with newly diagnosed glioblastoma. Arch Neurol 67: 313-319.
-
(2010)
Arch Neurol
, vol.67
, pp. 313-319
-
-
Nabors, L.B.1
Fiveash, J.B.2
Markert, J.M.3
Kekan, M.S.4
Gillespie, G.Y.5
Huang, Z.6
Johnson, M.J.7
Meleth, S.8
Kuo, H.9
Gladson, C.L.10
-
63
-
-
56649123212
-
Risk of venous thromboembolism with the angiogenesis inhibitor bevacizumab in cancer patients: A meta-analysis
-
Nalluri SR, Chu D, Keresztes R, Zhu X, Wu S. 2008. Risk of venous thromboembolism with the angiogenesis inhibitor bevacizumab in cancer patients: A meta-analysis. JAMA 300: 2277-2285.
-
(2008)
JAMA
, vol.300
, pp. 2277-2285
-
-
Nalluri, S.R.1
Chu, D.2
Keresztes, R.3
Zhu, X.4
Wu, S.5
-
64
-
-
0028157338
-
Matrix-bound thrombospondin promotes angiogenesis in vitro
-
Nicosia RF, Tuszynski GP. 1994. Matrix-bound thrombospondin promotes angiogenesis in vitro. J Cell Biol 124: 183-193.
-
(1994)
J Cell Biol
, vol.124
, pp. 183-193
-
-
Nicosia, R.F.1
Tuszynski, G.P.2
-
65
-
-
39449127385
-
Thrombospondins use the VLDL receptor and a nonapoptotic pathway to inhibit cell division in microvascular endothelial cells
-
Oganesian A, Armstrong LC, Migliorini MM, Strickland DK, Bornstein P. 2008. Thrombospondins use the VLDL receptor and a nonapoptotic pathway to inhibit cell division in microvascular endothelial cells. Mol Biol Cell 19: 563-571.
-
(2008)
Mol Biol Cell
, vol.19
, pp. 563-571
-
-
Oganesian, A.1
Armstrong, L.C.2
Migliorini, M.M.3
Strickland, D.K.4
Bornstein, P.5
-
66
-
-
48249112290
-
Improved vascular engraftment and graft function after inhibition of the angiostatic factor thrombospondin-1 in mouse pancreatic islets
-
Olerud J, Johansson M, Lawler J, Welsh N, Carlsson PO. 2008. Improved vascular engraftment and graft function after inhibition of the angiostatic factor thrombospondin-1 in mouse pancreatic islets. Diabetes 57: 1870-1877.
-
(2008)
Diabetes
, vol.57
, pp. 1870-1877
-
-
Olerud, J.1
Johansson, M.2
Lawler, J.3
Welsh, N.4
Carlsson, P.O.5
-
67
-
-
0029278614
-
A marker-free method to estimate joint centre of rotation by video image processing
-
Persson T, Lanshammar H, Medved V. 1995. A marker-free method to estimate joint centre of rotation by video image processing. Comput Methods Programs Biomed 46: 217-224.
-
(1995)
Comput Methods Programs Biomed
, vol.46
, pp. 217-224
-
-
Persson, T.1
Lanshammar, H.2
Medved, V.3
-
68
-
-
26444476029
-
Identification of CD36 molecular features required for its in vitro angiostatic activity
-
Primo L, Ferrandi C, Roca C, Marchio S, di Blasio L, Alessio M, Bussolino F. 2005. Identification of CD36 molecular features required for its in vitro angiostatic activity. FASEB J 19: 1713-1715.
-
(2005)
FASEB J
, vol.19
, pp. 1713-1715
-
-
Primo, L.1
Ferrandi, C.2
Roca, C.3
Marchio, S.4
di Blasio, L.5
Alessio, M.6
Bussolino, F.7
-
69
-
-
0037051655
-
Inhibition of tumor growth by systemic treatment with thrombospondin-1 peptide mimetics
-
Reiher FK, Volpert OV, Jimenez B, Crawford SE, Dinney CP, Henkin J, Haviv F, Bouck NP, Campbell SC. 2002. Inhibition of tumor growth by systemic treatment with thrombospondin-1 peptide mimetics. Int J Cancer 98: 682-689.
-
(2002)
Int J Cancer
, vol.98
, pp. 682-689
-
-
Reiher, F.K.1
Volpert, O.V.2
Jimenez, B.3
Crawford, S.E.4
Dinney, C.P.5
Henkin, J.6
Haviv, F.7
Bouck, N.P.8
Campbell, S.C.9
-
70
-
-
65949084271
-
A double hit to kill tumor and endothelial cells by TRAIL and antiangiogenic 3TSR
-
Ren B, Song K, Parangi S, Jin T, Ye M, Humphreys R, Duquette M, Zhang X, Benhaga N, Lawler J, Khosravi-Far R. 2009. A double hit to kill tumor and endothelial cells by TRAIL and antiangiogenic 3TSR. Cancer Res 69: 3856-3865.
-
(2009)
Cancer Res
, vol.69
, pp. 3856-3865
-
-
Ren, B.1
Song, K.2
Parangi, S.3
Jin, T.4
Ye, M.5
Humphreys, R.6
Duquette, M.7
Zhang, X.8
Benhaga, N.9
Lawler, J.10
Khosravi-Far, R.11
-
71
-
-
24944556468
-
Nitric oxide regulates angiogenesis through a functional switch involving thrombospondin-1
-
Ridnour LA, Isenberg JS, Espey MG, Thomas DD, Roberts DD, Wink DA. 2005. Nitric oxide regulates angiogenesis through a functional switch involving thrombospondin-1. Proc Natl Acad Sci 102: 13147-13152.
-
(2005)
Proc Natl Acad Sci
, vol.102
, pp. 13147-13152
-
-
Ridnour, L.A.1
Isenberg, J.S.2
Espey, M.G.3
Thomas, D.D.4
Roberts, D.D.5
Wink, D.A.6
-
73
-
-
0035940429
-
Thrombospondin-1 suppresses spontaneous tumor growth and inhibits activation of matrix metalloproteinase-9 and mobilization of vascular endothelial growth factor
-
Rodriguez-Manzaneque JC, Lane TF, Ortega MA, Hynes RO, Lawler J, Iruela-Arispe ML. 2001. Thrombospondin-1 suppresses spontaneous tumor growth and inhibits activation of matrix metalloproteinase-9 and mobilization of vascular endothelial growth factor. Proc Natl Acad Sci 98: 12485-12490.
-
(2001)
Proc Natl Acad Sci
, vol.98
, pp. 12485-12490
-
-
Rodriguez-Manzaneque, J.C.1
Lane, T.F.2
Ortega, M.A.3
Hynes, R.O.4
Lawler, J.5
Iruela-Arispe, M.L.6
-
74
-
-
63849148548
-
Assessment of therapeutic efficacy and fate of engineered human mesenchymal stem cells for cancer therapy
-
Sasportas LS, Kasmieh R, Wakimoto H, Hingtgen S, van de Water JA, MohapatraG, Figueiredo JL, Martuza RL, Weissleder R, Shah K. 2009. Assessment of therapeutic efficacy and fate of engineered human mesenchymal stem cells for cancer therapy. Proc Natl Acad Sci 106: 4822-4827.
-
(2009)
Proc Natl Acad Sci
, vol.106
, pp. 4822-4827
-
-
Sasportas, L.S.1
Kasmieh, R.2
Wakimoto, H.3
Hingtgen, S.4
van de Water, J.A.5
Mohapatra, G.6
Figueiredo, J.L.7
Martuza, R.L.8
Weissleder, R.9
Shah, K.10
-
75
-
-
19944432454
-
Genetic heterogeneity of the vasculogenic phenotype parallels angiogenesis: Implications for cellular surrogate marker analysis of antiangiogenesis
-
Shaked Y, Bertolini F, Man S, Rogers MS, Cervi D, Foutz T, Rawn K, Voskas D, Dumont DJ, Ben-David Y, et al. 2005. Genetic heterogeneity of the vasculogenic phenotype parallels angiogenesis: Implications for cellular surrogate marker analysis of antiangiogenesis. Cancer Cell 7: 101-111.
-
(2005)
Cancer Cell
, vol.7
, pp. 101-111
-
-
Shaked, Y.1
Bertolini, F.2
Man, S.3
Rogers, M.S.4
Cervi, D.5
Foutz, T.6
Rawn, K.7
Voskas, D.8
Dumont, D.J.9
Ben-David, Y.10
-
76
-
-
13944267041
-
Inhibition of endothelial cell migration by thrombospondin-1 type-1 repeats is mediated by beta1 integrins
-
Short SM, Derrien A, Narsimhan RP, Lawler J, Ingber DE, Zetter BR. 2005. Inhibition of endothelial cell migration by thrombospondin-1 type-1 repeats is mediated by beta1 integrins. J Cell Biol 168: 643-653.
-
(2005)
J Cell Biol
, vol.168
, pp. 643-653
-
-
Short, S.M.1
Derrien, A.2
Narsimhan, R.P.3
Lawler, J.4
Ingber, D.E.5
Zetter, B.R.6
-
77
-
-
14644433781
-
The antiangiogenic effect of thrombospondin-2 is mediated by CD36 and modulated by histidine-rich glycoprotein
-
Simantov R, Febbraio M, Silverstein RL. 2005. The antiangiogenic effect of thrombospondin-2 is mediated by CD36 and modulated by histidine-rich glycoprotein. Matrix Biol 24: 27-34.
-
(2005)
Matrix Biol
, vol.24
, pp. 27-34
-
-
Simantov, R.1
Febbraio, M.2
Silverstein, R.L.3
-
78
-
-
0036531805
-
Systemic inhibition of tumor growth and angiogenesis by thrombospondin-2 using cell-based antiangiogenic gene therapy
-
Streit M, Stephen AE, Hawighorst T, Matsuda K, Lange-Asschenfeldt B, BrownLF, Vacanti JP, Detmar M. 2002. Systemic inhibition of tumor growth and angiogenesis by thrombospondin-2 using cell-based antiangiogenic gene therapy. Cancer Res 62: 2004-2012.
-
(2002)
Cancer Res
, vol.62
, pp. 2004-2012
-
-
Streit, M.1
Stephen, A.E.2
Hawighorst, T.3
Matsuda, K.4
Lange-Asschenfeldt, B.5
Brown, L.F.6
Vacanti, J.P.7
Detmar, M.8
-
79
-
-
66149122536
-
Thrombospondin-1 modulates VEGF-A-mediated Akt signaling and capillary survival in the developing retina
-
Sun J, Hopkins BD, Tsujikawa K, Perruzzi C, Adini I, Swerlick R, Bornstein P, Lawler J, Benjamin LE. 2009. Thrombospondin-1 modulates VEGF-A-mediated Akt signaling and capillary survival in the developing retina. Am J Physiol Heart Circ Physiol 296: H1344-H1351.
-
(2009)
Am J Physiol Heart Circ Physiol
, vol.296
-
-
Sun, J.1
Hopkins, B.D.2
Tsujikawa, K.3
Perruzzi, C.4
Adini, I.5
Swerlick, R.6
Bornstein, P.7
Lawler, J.8
Benjamin, L.E.9
-
80
-
-
0037191047
-
Crystal structure of the TSP-1 type 1 repeats: A novel layered fold and its biological implication
-
Tan K, Duquette M, Liu JH, Dong Y, Zhang R, Joachimiak A, Lawler J, Wang JH. 2002. Crystal structure of the TSP-1 type 1 repeats: A novel layered fold and its biological implication. J Cell Biol 159: 373-382.
-
(2002)
J Cell Biol
, vol.159
, pp. 373-382
-
-
Tan, K.1
Duquette, M.2
Liu, J.H.3
Dong, Y.4
Zhang, R.5
Joachimiak, A.6
Lawler, J.7
Wang, J.H.8
-
81
-
-
0025370524
-
Platelet thrombospondin modulates endothelial cell adhesion, motility, and growth: A potential angiogenesis regulatory factor
-
Taraboletti G, Roberts D, Liotta LA, Giavazzi R. 1990. Platelet thrombospondin modulates endothelial cell adhesion, motility, and growth: A potential angiogenesis regulatory factor. J Cell Biol 111: 765-772.
-
(1990)
J Cell Biol
, vol.111
, pp. 765-772
-
-
Taraboletti, G.1
Roberts, D.2
Liotta, L.A.3
Giavazzi, R.4
-
82
-
-
31044432914
-
Identification of thrombospondin 1 (TSP-1) as a novel mediator of cell injury in kidney ischemia
-
Thakar CV, Zahedi K, Revelo MP, Wang Z, Burnham CE, Barone S, Bevans S, Lentsch AB, Rabb H, Soleimani M. 2005. Identification of thrombospondin 1 (TSP-1) as a novel mediator of cell injury in kidney ischemia. J Clin Invest 115: 3451-3459.
-
(2005)
J Clin Invest
, vol.115
, pp. 3451-3459
-
-
Thakar, C.V.1
Zahedi, K.2
Revelo, M.P.3
Wang, Z.4
Burnham, C.E.5
Barone, S.6
Bevans, S.7
Lentsch, A.B.8
Rabb, H.9
Soleimani, M.10
-
83
-
-
3242772439
-
The thrombospondin type 1 repeat superfamily
-
Tucker RP. 2004. The thrombospondin type 1 repeat superfamily. Int J Biochem Cell Biol 36: 969-974.
-
(2004)
Int J Biochem Cell Biol
, vol.36
, pp. 969-974
-
-
Tucker, R.P.1
-
84
-
-
77953232760
-
Human stem cells expressing novel TSP-1 variant have anti-angiogenic effect on brain tumors
-
van Eekelen M, Sasportas LS, Kasmieh R, Yip S, Figueiredo JL, Louis DN, Weissleder R, Shah K. 2010. Human stem cells expressing novel TSP-1 variant have anti-angiogenic effect on brain tumors. Oncogene 29: 3185-3195.
-
(2010)
Oncogene
, vol.29
, pp. 3185-3195
-
-
van Eekelen, M.1
Sasportas, L.S.2
Kasmieh, R.3
Yip, S.4
Figueiredo, J.L.5
Louis, D.N.6
Weissleder, R.7
Shah, K.8
-
85
-
-
0036104828
-
Inducer-stimulated Fas targets activated endothelium for destruction by anti-angiogenic thrombospondin-1 and pigment epithelium-derived factor
-
Volpert OV, Zaichuk T, Zhou W, Reiher F, Ferguson TA, Stuart PM, Amin M, Bouck NP. 2002. Inducer-stimulated Fas targets activated endothelium for destruction by anti-angiogenic thrombospondin-1 and pigment epithelium-derived factor. Nat Med 8: 349-357.
-
(2002)
Nat Med
, vol.8
, pp. 349-357
-
-
Volpert, O.V.1
Zaichuk, T.2
Zhou, W.3
Reiher, F.4
Ferguson, T.A.5
Stuart, P.M.6
Amin, M.7
Bouck, N.P.8
-
86
-
-
13844292108
-
Internalization but not binding of thrombospondin-1 to low density lipoprotein receptor-related protein-1 requires heparan sulfate proteoglycans
-
Wang S, Herndon ME, Ranganathan S, Godyna S, Lawler J, Argraves WS, Liau G. 2004. Internalization but not binding of thrombospondin-1 to low density lipoprotein receptor-related protein-1 requires heparan sulfate proteoglycans. J Cell Biochem 91: 766-776.
-
(2004)
J Cell Biochem
, vol.91
, pp. 766-776
-
-
Wang, S.1
Herndon, M.E.2
Ranganathan, S.3
Godyna, S.4
Lawler, J.5
Argraves, W.S.6
Liau, G.7
-
87
-
-
33646922275
-
Enhanced proangiogenic signaling in thrombospondin-1-deficient retinal endothelial cells
-
Wang Y, Wang S, Sheibani N. 2006. Enhanced proangiogenic signaling in thrombospondin-1-deficient retinal endothelial cells. Microvasc Res 71: 143-151.
-
(2006)
Microvasc Res
, vol.71
, pp. 143-151
-
-
Wang, Y.1
Wang, S.2
Sheibani, N.3
-
88
-
-
34547768293
-
Novel antiangiogenic pathway of thrombospondin-1 mediated by suppression of the cell cycle
-
Yamauchi M, Imajoh-Ohmi S, Shibuya M. 2007. Novel antiangiogenic pathway of thrombospondin-1 mediated by suppression of the cell cycle. Cancer Sci 98: 1491-1497.
-
(2007)
Cancer Sci
, vol.98
, pp. 1491-1497
-
-
Yamauchi, M.1
Imajoh-Ohmi, S.2
Shibuya, M.3
-
89
-
-
25144488561
-
Metronomic low-dose chemotherapy boosts CD95-dependent antiangiogenic effect of the thrombospondin peptide ABT-510: A complementation antiangiogenic strategy
-
Yap R, Veliceasa D, Emmenegger U, Kerbel RS, McKay LM, Henkin J, VolpertOV. 2005. Metronomic low-dose chemotherapy boosts CD95-dependent antiangiogenic effect of the thrombospondin peptide ABT-510: A complementation antiangiogenic strategy. Clin Cancer Res 11: 6678-6685.
-
(2005)
Clin Cancer Res
, vol.11
, pp. 6678-6685
-
-
Yap, R.1
Veliceasa, D.2
Emmenegger, U.3
Kerbel, R.S.4
McKay, L.M.5
Henkin, J.6
Volpert, O.V.7
-
90
-
-
23344452702
-
Endothelial nitric oxide synthase is critical for ischemic remodeling, mural cell recruitment, and blood flow reserve
-
Yu J, deMuinck ED, Zhuang Z, Drinane M, Kauser K, Rubanyi GM, Qian HS, Murata T, Escalante B, Sessa WC. 2005. Endothelial nitric oxide synthase is critical for ischemic remodeling, mural cell recruitment, and blood flow reserve. Proc Natl Acad Sci 102: 10999-11004.
-
(2005)
Proc Natl Acad Sci
, vol.102
, pp. 10999-11004
-
-
Yu, J.1
deMuinck, E.D.2
Zhuang, Z.3
Drinane, M.4
Kauser, K.5
Rubanyi, G.M.6
Qian, H.S.7
Murata, T.8
Escalante, B.9
Sessa, W.C.10
-
91
-
-
77957160710
-
Regional control of tumor growth
-
Zaslavsky A, Chen C, Grillo J, Baek KH, Holmgren L, Yoon SS, Folkman J, Ryeom S. 2010. Regional control of tumor growth. Mol Cancer Res 8: 1198-1206.
-
(2010)
Mol Cancer Res
, vol.8
, pp. 1198-1206
-
-
Zaslavsky, A.1
Chen, C.2
Grillo, J.3
Baek, K.H.4
Holmgren, L.5
Yoon, S.S.6
Folkman, J.7
Ryeom, S.8
-
92
-
-
34548821303
-
Thrombospondin-based antiangiogenic therapy
-
Zhang X, Lawler J. 2007. Thrombospondin-based antiangiogenic therapy. Microvasc Res 74: 90-99.
-
(2007)
Microvasc Res
, vol.74
, pp. 90-99
-
-
Zhang, X.1
Lawler, J.2
-
93
-
-
16844380395
-
Antiangiogenic treatment with the three thrombospondin-1 type 1 repeats recombinant protein in an orthotopic human pancreatic cancer model
-
Zhang X, Galardi E, Duquette M, Delic M, Lawler J, Parangi S. 2005. Antiangiogenic treatment with the three thrombospondin-1 type 1 repeats recombinant protein in an orthotopic human pancreatic cancer model. Clin Cancer Res 11: 2337-2344.
-
(2005)
Clin Cancer Res
, vol.11
, pp. 2337-2344
-
-
Zhang, X.1
Galardi, E.2
Duquette, M.3
Delic, M.4
Lawler, J.5
Parangi, S.6
-
94
-
-
33845674173
-
Continuous administration of the three thrombospondin-1 type 1 repeats recombinant protein improves the potency of therapy in an orthotopic human pancreatic cancer model
-
Zhang X, Connolly C, Duquette M, Lawler J, Parangi S. 2007. Continuous administration of the three thrombospondin-1 type 1 repeats recombinant protein improves the potency of therapy in an orthotopic human pancreatic cancer model. Cancer Lett 247: 143-149.
-
(2007)
Cancer Lett
, vol.247
, pp. 143-149
-
-
Zhang, X.1
Connolly, C.2
Duquette, M.3
Lawler, J.4
Parangi, S.5
-
95
-
-
70349658097
-
Thrombospondin-1 modulates vascular endothelial growth factor activity at the receptor level
-
Zhang X, Kazerounian S, Duquette M, Perruzzi C, Nagy JA, Dvorak HF, ParangiS, Lawler J. 2009. Thrombospondin-1 modulates vascular endothelial growth factor activity at the receptor level. FASEB J 23: 3368-3376.
-
(2009)
FASEB J
, vol.23
, pp. 3368-3376
-
-
Zhang, X.1
Kazerounian, S.2
Duquette, M.3
Perruzzi, C.4
Nagy, J.A.5
Dvorak, H.F.6
Parangi, S.7
Lawler, J.8
|