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Volumn 2, Issue 5, 2012, Pages

Molecular basis for the regulation of angiogenesis by thrombospondin-1 and -2

Author keywords

[No Author keywords available]

Indexed keywords

CD36 ANTIGEN; CD47 ANTIGEN; CISPLATIN; CYCLOPHOSPHAMIDE; N ACETYLSARCOSYLGLYCYLVALYL DEXTRO ALLOISOLEUCYLTHREONYLNORVALYLISOLEUCYLARGINYLPROLINE ETHYLAMIDE; THROMBOSPONDIN 1; THROMBOSPONDIN 2; VASCULOTROPIN; ANGIOGENESIS INHIBITOR; ANTINEOPLASTIC AGENT; FYN PROTEIN, HUMAN; LEUKOCYTE ANTIGEN; NITRIC OXIDE; PROTEIN KINASE FYN; THROMBOSPONDIN; VASCULOTROPIN A; VASCULOTROPIN RECEPTOR;

EID: 84867268459     PISSN: None     EISSN: 21571422     Source Type: Journal    
DOI: 10.1101/cshperspect.a006627     Document Type: Article
Times cited : (392)

References (95)
  • 1
    • 43049088843 scopus 로고    scopus 로고
    • Stem and progenitor cell-mediated tumor selective gene therapy
    • Aboody KS, Najbauer J, Danks MK. 2008. Stem and progenitor cell-mediated tumor selective gene therapy. Gene Ther 15: 739-752.
    • (2008) Gene Ther , vol.15 , pp. 739-752
    • Aboody, K.S.1    Najbauer, J.2    Danks, M.K.3
  • 3
    • 34548219477 scopus 로고    scopus 로고
    • ABT-510, a modified type 1 repeat peptide of thrombospondin, inhibits malignant glioma growth in vivo by inhibiting angiogenesis
    • Anderson JC, Grammer JR, Wang W, Nabors LB, Henkin J, Stewart JE Jr., GladsonCL. 2007. ABT-510, a modified type 1 repeat peptide of thrombospondin, inhibits malignant glioma growth in vivo by inhibiting angiogenesis. Cancer Biol Ther 6: 454-462.
    • (2007) Cancer Biol Ther , vol.6 , pp. 454-462
    • Anderson, J.C.1    Grammer, J.R.2    Wang, W.3    Nabors, L.B.4    Henkin, J.5    Stewart Jr., J.E.6    Gladson, C.L.7
  • 5
    • 0025171017 scopus 로고
    • Specific inhibition of endothelial cell proliferation by thrombospondin
    • Bagavandoss P, Wilks JW. 1990. Specific inhibition of endothelial cell proliferation by thrombospondin. Biochem Biophys Res Commun 170: 867-872.
    • (1990) Biochem Biophys Res Commun , vol.170 , pp. 867-872
    • Bagavandoss, P.1    Wilks, J.W.2
  • 7
    • 0034644748 scopus 로고    scopus 로고
    • Thrombospondin type 1 repeats interact with matrix metalloproteinase 2. Regulation of metalloproteinase activity
    • Bein K, Simons M. 2000. Thrombospondin type 1 repeats interact with matrix metalloproteinase 2. Regulation of metalloproteinase activity. J Biol Chem 275: 32167-32173.
    • (2000) J Biol Chem , vol.275 , pp. 32167-32173
    • Bein, K.1    Simons, M.2
  • 8
    • 0027745333 scopus 로고
    • Thrombospondin and in vivo angiogenesis induced by basic fibroblast growth factor or lipopolysaccharide
    • BenEzra D, Griffin BW, Maftzir G, Aharonov O. 1993. Thrombospondin and in vivo angiogenesis induced by basic fibroblast growth factor or lipopolysaccharide. Invest Ophthalmol Vis Sci 34: 3601-3608.
    • (1993) Invest Ophthalmol Vis Sci , vol.34 , pp. 3601-3608
    • BenEzra, D.1    Griffin, B.W.2    Maftzir, G.3    Aharonov, O.4
  • 9
    • 0242331613 scopus 로고    scopus 로고
    • Thrombospondin 1, a mediator of the antiangiogenic effects of low-dose metronomic chemotherapy
    • Bocci G, Francia G, Man S, Lawler J, Kerbel RS. 2003. Thrombospondin 1, a mediator of the antiangiogenic effects of low-dose metronomic chemotherapy. Proc Natl Acad Sci 100: 12917-12922.
    • (2003) Proc Natl Acad Sci , vol.100 , pp. 12917-12922
    • Bocci, G.1    Francia, G.2    Man, S.3    Lawler, J.4    Kerbel, R.S.5
  • 12
    • 77949621084 scopus 로고    scopus 로고
    • The thrombospondin-1 mimetic ABT-510 increases the uptake and effectiveness of cisplatin and paclitaxel in a mouse model of epithelial ovarian cancer
    • Campbell NE, Greenaway J, Henkin J, Moorehead RA, Petrik J. 2010. The thrombospondin-1 mimetic ABT-510 increases the uptake and effectiveness of cisplatin and paclitaxel in a mouse model of epithelial ovarian cancer. Neoplasia 12: 275-283.
    • (2010) Neoplasia , vol.12 , pp. 275-283
    • Campbell, N.E.1    Greenaway, J.2    Henkin, J.3    Moorehead, R.A.4    Petrik, J.5
  • 13
    • 0033734494 scopus 로고    scopus 로고
    • The cell biology of thrombospondin-1
    • Chen H, Herndon ME, Lawler J. 2000. The cell biology of thrombospondin-1. Matrix Biol 19: 597-614.
    • (2000) Matrix Biol , vol.19 , pp. 597-614
    • Chen, H.1    Herndon, M.E.2    Lawler, J.3
  • 14
    • 67649099677 scopus 로고    scopus 로고
    • Antiangiogenic strategies for treatment of malignant gliomas
    • Chi AS, Norden AD, Wen PY. 2009a. Antiangiogenic strategies for treatment of malignant gliomas. Neurotherapeutics 6: 513-526.
    • (2009) Neurotherapeutics , vol.6 , pp. 513-526
    • Chi, A.S.1    Norden, A.D.2    Wen, P.Y.3
  • 15
    • 68049113584 scopus 로고    scopus 로고
    • Angiogenesis as a therapeutic target in malignant gliomas
    • Chi AS, Sorensen AG, Jain RK, Batchelor TT. 2009b. Angiogenesis as a therapeutic target in malignant gliomas. Oncologist 14: 621-636.
    • (2009) Oncologist , vol.14 , pp. 621-636
    • Chi, A.S.1    Sorensen, A.G.2    Jain, R.K.3    Batchelor, T.T.4
  • 16
    • 77950551541 scopus 로고    scopus 로고
    • Non-peptidic thrombospondin-1 mimics as fibroblast growth factor-2 inhibitors: An integrated strategy for the development of new antiangiogenic compounds
    • Colombo G, Margosio B, Ragona L, Neves M, Bonifacio S, Annis DS, StravalaciM, Tomaselli S, Giavazzi R, Rusnati M, et al. 2010. Non-peptidic thrombospondin-1 mimics as fibroblast growth factor-2 inhibitors: An integrated strategy for the development of new antiangiogenic compounds. J Biol Chem 285: 8733-8742.
    • (2010) J Biol Chem , vol.285 , pp. 8733-8742
    • Colombo, G.1    Margosio, B.2    Ragona, L.3    Neves, M.4    Bonifacio, S.5    Annis, D.S.6    Stravalaci, M.7    Tomaselli, S.8    Giavazzi, R.9    Rusnati, M.10
  • 18
    • 0033027727 scopus 로고    scopus 로고
    • Three distinct D-amino acid substitutions confer potent antiangiogenic activity on an inactive peptide derived from a thrombospondin-1 type 1 repeat
    • Dawson DW, Volpert OV, Pearce SF, Schneider AJ, Silverstein RL, Henkin J, Bouck NP. 1999. Three distinct D-amino acid substitutions confer potent antiangiogenic activity on an inactive peptide derived from a thrombospondin-1 type 1 repeat. Mol Pharmacol 55: 332-338.
    • (1999) Mol Pharmacol , vol.55 , pp. 332-338
    • Dawson, D.W.1    Volpert, O.V.2    Pearce, S.F.3    Schneider, A.J.4    Silverstein, R.L.5    Henkin, J.6    Bouck, N.P.7
  • 19
    • 58149151390 scopus 로고    scopus 로고
    • Circulating endothelial cells, bone marrow-derived endothelial progenitor cells and proangiogenic hematopoietic cells in cancer: From biology to therapy
    • Dome B, Timar J, Ladanyi A, Paku S, Renyi-Vamos F, Klepetko W, Lang G, Dome P, Bogos K, Tovari J. 2009. Circulating endothelial cells, bone marrow-derived endothelial progenitor cells and proangiogenic hematopoietic cells in cancer: From biology to therapy. Crit Rev Oncol Hematol 69: 108-124.
    • (2009) Crit Rev Oncol Hematol , vol.69 , pp. 108-124
    • Dome, B.1    Timar, J.2    Ladanyi, A.3    Paku, S.4    Renyi-Vamos, F.5    Klepetko, W.6    Lang, G.7    Dome, P.8    Bogos, K.9    Tovari, J.10
  • 20
    • 1642619061 scopus 로고    scopus 로고
    • Role of eNOS in neovascularization: NO for endothelial progenitor cells
    • Duda DG, Fukumura D, Jain RK. 2004. Role of eNOS in neovascularization: NO for endothelial progenitor cells. Trends Mol Med 10: 143-145.
    • (2004) Trends Mol Med , vol.10 , pp. 143-145
    • Duda, D.G.1    Fukumura, D.2    Jain, R.K.3
  • 21
    • 34250731849 scopus 로고    scopus 로고
    • Life history of eNOS: Partners and pathways
    • Dudzinski DM, Michel T. 2007. Life history of eNOS: Partners and pathways. Cardiovasc Res 75: 247-260.
    • (2007) Cardiovasc Res , vol.75 , pp. 247-260
    • Dudzinski, D.M.1    Michel, T.2
  • 23
    • 0036070105 scopus 로고    scopus 로고
    • 2-terminal heparin-binding domain of the adhesive glycoprotein, thrombospondin-1, promotes endothelial tube formation and cell survival: A possible role for syndecan-4 proteoglycan
    • 2-terminal heparin-binding domain of the adhesive glycoprotein, thrombospondin-1, promotes endothelial tube formation and cell survival: A possible role for syndecan-4 proteoglycan. Matrix Biol 21: 311-324.
    • (2002) Matrix Biol , vol.21 , pp. 311-324
    • Ferrari do Outeiro-Bernstein, M.A.1    Nunes, S.S.2    Andrade, A.C.3    Alves, T.R.4    Legrand, C.5    Morandi, V.6
  • 24
    • 85013312416 scopus 로고
    • Tumor angiogenesis: Therapeutic implications
    • Folkman J. 1971. Tumor angiogenesis: Therapeutic implications. N Engl J Med 285: 1182-1186.
    • (1971) N Engl J Med , vol.285 , pp. 1182-1186
    • Folkman, J.1
  • 25
    • 0035956947 scopus 로고    scopus 로고
    • Predominant role of endothelial nitric oxide synthase in vascular endothelial growth factor-induced angiogenesis and vascular permeability
    • Fukumura D, Gohongi T, Kadambi A, Izumi Y, Ang J, Yun CO, Buerk DG, HuangPL, Jain RK. 2001. Predominant role of endothelial nitric oxide synthase in vascular endothelial growth factor-induced angiogenesis and vascular permeability. Proc Natl Acad Sci 98: 2604-2609.
    • (2001) Proc Natl Acad Sci , vol.98 , pp. 2604-2609
    • Fukumura, D.1    Gohongi, T.2    Kadambi, A.3    Izumi, Y.4    Ang, J.5    Yun, C.O.6    Buerk, D.G.7    Huang, P.L.8    Jain, R.K.9
  • 27
    • 0025147371 scopus 로고
    • A tumor suppressor-dependent inhibitor of angiogenesis is immunologically and functionally indistinguishable from a fragment of thrombospondin
    • Good DJ, Polverini PJ, Rastinejad F, Le Beau MM, Lemons RS, Frazier WA, BouckNP. 1990. A tumor suppressor-dependent inhibitor of angiogenesis is immunologically and functionally indistinguishable from a fragment of thrombospondin. Proc Natl Acad Sci 87: 6624-6628.
    • (1990) Proc Natl Acad Sci , vol.87 , pp. 6624-6628
    • Good, D.J.1    Polverini, P.J.2    Rastinejad, F.3    Le Beau, M.M.4    Lemons, R.S.5    Frazier, W.A.6    Bouck, N.P.7
  • 28
    • 57649139197 scopus 로고    scopus 로고
    • A phase 1 trial of 2 dose schedules of ABT-510, an antiangiogenic, thrombospondin-1-mimetic peptide, in patients with advanced cancer
    • Gordon MS, Mendelson D, Carr R, Knight RA, Humerickhouse RA, Iannone M, Stopeck AT. 2008. A phase 1 trial of 2 dose schedules of ABT-510, an antiangiogenic, thrombospondin-1-mimetic peptide, in patients with advanced cancer. Cancer 113: 3420-3429.
    • (2008) Cancer , vol.113 , pp. 3420-3429
    • Gordon, M.S.1    Mendelson, D.2    Carr, R.3    Knight, R.A.4    Humerickhouse, R.A.5    Iannone, M.6    Stopeck, A.T.7
  • 29
    • 33846598411 scopus 로고    scopus 로고
    • Thrombospondin-1 inhibits VEGF levels in the ovary directly by binding and internalization via the low density lipoprotein receptor-related protein-1 (LRP-1)
    • Greenaway J, Lawler J, Moorehead R, Bornstein P, Lamarre J, Petrik J. 2007. Thrombospondin-1 inhibits VEGF levels in the ovary directly by binding and internalization via the low density lipoprotein receptor-related protein-1 (LRP-1). J Cell Physiol 210: 807-818.
    • (2007) J Cell Physiol , vol.210 , pp. 807-818
    • Greenaway, J.1    Lawler, J.2    Moorehead, R.3    Bornstein, P.4    Lamarre, J.5    Petrik, J.6
  • 30
    • 58149521990 scopus 로고    scopus 로고
    • ABT-510 induces tumor cell apoptosis and inhibits ovarian tumor growth in an orthotopic, syngeneic model of epithelial ovarian cancer
    • Greenaway J, Henkin J, Lawler J, Moorehead R, Petrik J. 2009. ABT-510 induces tumor cell apoptosis and inhibits ovarian tumor growth in an orthotopic, syngeneic model of epithelial ovarian cancer. Mol Cancer Ther 8: 64-74.
    • (2009) Mol Cancer Ther , vol.8 , pp. 64-74
    • Greenaway, J.1    Henkin, J.2    Lawler, J.3    Moorehead, R.4    Petrik, J.5
  • 31
    • 0030874871 scopus 로고    scopus 로고
    • Antiproliferative and antitumor activities of D-reverse peptides derived from the second type-1 repeat of thrombospondin-1
    • Guo NH, Krutzsch HC, Inman JK, Shannon CS, Roberts DD. 1997. Antiproliferative and antitumor activities of D-reverse peptides derived from the second type-1 repeat of thrombospondin-1. J Pept Res 50: 210-221.
    • (1997) J Pept Res , vol.50 , pp. 210-221
    • Guo, N.H.1    Krutzsch, H.C.2    Inman, J.K.3    Shannon, C.S.4    Roberts, D.D.5
  • 32
    • 0009849965 scopus 로고    scopus 로고
    • Binding and displacement of vascular endothelial growth factor (VEGF) by thrombospondin: Effect on human microvascular endothelial cell proliferation and angiogenesis
    • Gupta K, Gupta P, Wild R, Ramakrishnan S, Hebbel RP. 1999. Binding and displacement of vascular endothelial growth factor (VEGF) by thrombospondin: Effect on human microvascular endothelial cell proliferation and angiogenesis. Angiogenesis 3: 147-158.
    • (1999) Angiogenesis , vol.3 , pp. 147-158
    • Gupta, K.1    Gupta, P.2    Wild, R.3    Ramakrishnan, S.4    Hebbel, R.P.5
  • 33
    • 0030576517 scopus 로고    scopus 로고
    • Patterns and emerging mechanisms of the angiogenic switch during tumorigenesis
    • Hanahan D, Folkman J. 1996. Patterns and emerging mechanisms of the angiogenic switch during tumorigenesis. Cell 86: 353-364.
    • (1996) Cell , vol.86 , pp. 353-364
    • Hanahan, D.1    Folkman, J.2
  • 34
    • 20944443196 scopus 로고    scopus 로고
    • Thrombospondin-1 mimetic peptide inhibitors of angiogenesis and tumor growth: Design, synthesis, and optimization of pharmacokinetics and biological activities
    • Haviv F, Bradley MF, Kalvin DM, Schneider AJ, Davidson DJ, Majest SM, McKayLM, Haskell CJ, Bell RL, Nguyen B, et al. 2005. Thrombospondin-1 mimetic peptide inhibitors of angiogenesis and tumor growth: Design, synthesis, and optimization of pharmacokinetics and biological activities. J Med Chem 48: 2838-2846.
    • (2005) J Med Chem , vol.48 , pp. 2838-2846
    • Haviv, F.1    Bradley, M.F.2    Kalvin, D.M.3    Schneider, A.J.4    Davidson, D.J.5    Majest, S.M.6    McKay, L.M.7    Haskell, C.J.8    Bell, R.L.9    Nguyen, B.10
  • 38
    • 70849099495 scopus 로고    scopus 로고
    • The extracellular matrix: Not just pretty fibrils
    • Hynes RO. 2009. The extracellular matrix: Not just pretty fibrils. Science 326: 1216-1219.
    • (2009) Science , vol.326 , pp. 1216-1219
    • Hynes, R.O.1
  • 40
    • 65849137401 scopus 로고    scopus 로고
    • Regulation of thrombospondin1 by extracellular proteases
    • Iruela-Arispe ML. 2008. Regulation of thrombospondin1 by extracellular proteases. Curr Drug Targets 9: 863-868.
    • (2008) Curr Drug Targets , vol.9 , pp. 863-868
    • Iruela-Arispe, M.L.1
  • 41
    • 0033613226 scopus 로고    scopus 로고
    • Inhibition of angiogenesis by thrombospondin-1 is mediated by 2 independent regions within the type 1 repeats
    • Iruela-Arispe ML, Lombardo M, Krutzsch HC, Lawler J, Roberts DD. 1999. Inhibition of angiogenesis by thrombospondin-1 is mediated by 2 independent regions within the type 1 repeats. Circulation 100: 1423-1431.
    • (1999) Circulation , vol.100 , pp. 1423-1431
    • Iruela-Arispe, M.L.1    Lombardo, M.2    Krutzsch, H.C.3    Lawler, J.4    Roberts, D.D.5
  • 43
    • 33748747969 scopus 로고    scopus 로고
    • CD47 is necessary for inhibition of nitric oxide-stimulated vascular cell responses by thrombospondin-1
    • Isenberg JS, Ridnour LA, Dimitry J, Frazier WA, Wink DA, Roberts DD. 2006. CD47 is necessary for inhibition of nitric oxide-stimulated vascular cell responses by thrombospondin-1. J Biol Chem 281: 26069-26080.
    • (2006) J Biol Chem , vol.281 , pp. 26069-26080
    • Isenberg, J.S.1    Ridnour, L.A.2    Dimitry, J.3    Frazier, W.A.4    Wink, D.A.5    Roberts, D.D.6
  • 44
    • 34447508335 scopus 로고    scopus 로고
    • Thrombospondin-1 inhibits nitric oxide signaling via CD36 by inhibiting myristic acid uptake
    • Isenberg JS, Jia Y, Fukuyama J, Switzer CH, Wink DA, Roberts DD. 2007. Thrombospondin-1 inhibits nitric oxide signaling via CD36 by inhibiting myristic acid uptake. J Biol Chem 282: 15404-15415.
    • (2007) J Biol Chem , vol.282 , pp. 15404-15415
    • Isenberg, J.S.1    Jia, Y.2    Fukuyama, J.3    Switzer, C.H.4    Wink, D.A.5    Roberts, D.D.6
  • 46
    • 59449091909 scopus 로고    scopus 로고
    • Differential interactions of thrombospondin-1,-2, and-4 with CD47 and effects on cGMP signaling and ischemic injury responses
    • Isenberg JS, Annis DS, Pendrak ML, Ptaszynska M, Frazier WA, Mosher DF, Roberts DD. 2009a. Differential interactions of thrombospondin-1,-2, and-4 with CD47 and effects on cGMP signaling and ischemic injury responses. J Biol Chemo 284: 1116-1125.
    • (2009) J Biol Chemo , vol.284 , pp. 1116-1125
    • Isenberg, J.S.1    Annis, D.S.2    Pendrak, M.L.3    Ptaszynska, M.4    Frazier, W.A.5    Mosher, D.F.6    Roberts, D.D.7
  • 47
    • 60749091126 scopus 로고    scopus 로고
    • Regulation of nitric oxide signaling by thrombospondin 1: Implications for anti-angiogenic therapies
    • Isenberg JS, Martin-Manso G, Maxhimer JB, Roberts DD. 2009b. Regulation of nitric oxide signaling by thrombospondin 1: Implications for anti-angiogenic therapies. Nat Rev Cancer 9: 182-194.
    • (2009) Nat Rev Cancer , vol.9 , pp. 182-194
    • Isenberg, J.S.1    Martin-Manso, G.2    Maxhimer, J.B.3    Roberts, D.D.4
  • 48
    • 34447635695 scopus 로고    scopus 로고
    • Angiogenesis inhibitor therapies: Focus on kidney toxicity and hypertension
    • Izzedine H, Rixe O, Billemont B, Baumelou A, Deray G. 2007. Angiogenesis inhibitor therapies: Focus on kidney toxicity and hypertension. Am J Kidney Dis 50: 203-218.
    • (2007) Am J Kidney Dis , vol.50 , pp. 203-218
    • Izzedine, H.1    Rixe, O.2    Billemont, B.3    Baumelou, A.4    Deray, G.5
  • 50
    • 0035821779 scopus 로고    scopus 로고
    • c-Jun N-terminal kinase activation is required for the inhibition of neovascularization by thrombospondin-1
    • Jimenez B, Volpert OV, Reiher F, Chang L, Munoz A, Karin M, Bouck N. 2001. c-Jun N-terminal kinase activation is required for the inhibition of neovascularization by thrombospondin-1. Oncogene 20: 3443-3448.
    • (2001) Oncogene , vol.20 , pp. 3443-3448
    • Jimenez, B.1    Volpert, O.V.2    Reiher, F.3    Chang, L.4    Munoz, A.5    Karin, M.6    Bouck, N.7
  • 51
    • 0037219173 scopus 로고    scopus 로고
    • Brain angiogenesis inhibitor 1 is differentially expressed in normal brain and glioblastoma independently of p53 expression
    • Kaur B, Brat DJ, Calkins CC, Van Meir EG. 2003. Brain angiogenesis inhibitor 1 is differentially expressed in normal brain and glioblastoma independently of p53 expression. Am J Pathol 162: 19-27.
    • (2003) Am J Pathol , vol.162 , pp. 19-27
    • Kaur, B.1    Brat, D.J.2    Calkins, C.C.3    Van Meir, E.G.4
  • 52
    • 0035887379 scopus 로고    scopus 로고
    • Continuous administration of endostatin by intraperitoneally implanted osmotic pump improves the efficacy and potency of therapy in a mouse xenograft tumor model
    • Kisker O, Becker CM, Prox D, Fannon M, D'Amato R, Flynn E, Fogler WE, SimBK, Allred EN, Pirie-Shepherd, et al. 2001. Continuous administration of endostatin by intraperitoneally implanted osmotic pump improves the efficacy and potency of therapy in a mouse xenograft tumor model. Cancer Res 61: 7669-7674.
    • (2001) Cancer Res , vol.61 , pp. 7669-7674
    • Kisker, O.1    Becker, C.M.2    Prox, D.3    Fannon, M.4    D'Amato, R.5    Flynn, E.6    Fogler, W.E.7    Sim, B.K.8    Allred, E.N.9    Pirie-Shepherd10
  • 53
    • 79959706654 scopus 로고    scopus 로고
    • CD36-mediated activation of endothelial cell apoptosis by an N-terminal recombinant fragment of thrombospondin-2 inhibits breast cancer growth and metastasis in vivo
    • Koch M, Hussein F, Woeste A, Grundker C, Frontzek K, Emons G, HawighorstT. 2011. CD36-mediated activation of endothelial cell apoptosis by an N-terminal recombinant fragment of thrombospondin-2 inhibits breast cancer growth and metastasis in vivo. Breast Cancer Res Treat 128: 337-346.
    • (2011) Breast Cancer Res Treat , vol.128 , pp. 337-346
    • Koch, M.1    Hussein, F.2    Woeste, A.3    Grundker, C.4    Frontzek, K.5    Emons, G.6    Hawighorst, T.7
  • 54
    • 0018253429 scopus 로고
    • Isolation and characterization of a high molecular weight glycoprotein from human blood platelets
    • Lawler JW, Slayter HS, Coligan JE. 1978. Isolation and characterization of a high molecular weight glycoprotein from human blood platelets. J Biol Chem 253: 8609-8616.
    • (1978) J Biol Chem , vol.253 , pp. 8609-8616
    • Lawler, J.W.1    Slayter, H.S.2    Coligan, J.E.3
  • 55
    • 63849185760 scopus 로고    scopus 로고
    • Enhanced angiogenesis and reduced contraction in thrombospondin-2-null wounds is associated with increased levels of matrix metalloproteinases-2 and-9, and soluble VEGF
    • Maclauchlan S, Skokos EA, Agah A, Zeng J, Tian W, Davidson JM, Bornstein P, Kyriakides TR. 2009. Enhanced angiogenesis and reduced contraction in thrombospondin-2-null wounds is associated with increased levels of matrix metalloproteinases-2 and-9, and soluble VEGF. J Histochem Cytochem 57: 301-313.
    • (2009) J Histochem Cytochem , vol.57 , pp. 301-313
    • McLauchlan, S.1    Skokos, E.A.2    Agah, A.3    Zeng, J.4    Tian, W.5    Davidson, J.M.6    Bornstein, P.7    Kyriakides, T.R.8
  • 57
    • 0035503689 scopus 로고    scopus 로고
    • Thrombospondin-1 type 1 repeat recombinant proteins inhibit tumor growth through transforming growth factor-β-dependent and-independent mechanisms
    • Miao WM, Seng WL, Duquette M, Lawler P, Laus C, Lawler J. 2001. Thrombospondin-1 type 1 repeat recombinant proteins inhibit tumor growth through transforming growth factor-β-dependent and-independent mechanisms. Cancer Res 61: 7830-7839.
    • (2001) Cancer Res , vol.61 , pp. 7830-7839
    • Miao, W.M.1    Seng, W.L.2    Duquette, M.3    Lawler, P.4    Laus, C.5    Lawler, J.6
  • 58
    • 21644489952 scopus 로고    scopus 로고
    • Nitric oxide, VEGF, and VEGFR-2: Interactions in activity-induced angiogenesis in rat skeletal muscle
    • Milkiewicz M, Hudlicka O, Brown MD, Silgram H. 2005. Nitric oxide, VEGF, and VEGFR-2: Interactions in activity-induced angiogenesis in rat skeletal muscle. Am J Physiol Heart Circ Physiol 289: H336-H343.
    • (2005) Am J Physiol Heart Circ Physiol , vol.289
    • Milkiewicz, M.1    Hudlicka, O.2    Brown, M.D.3    Silgram, H.4
  • 59
    • 65849274263 scopus 로고    scopus 로고
    • Thrombospondin and apoptosis: Molecular mechanisms and use for design of complementation treatments
    • Mirochnik Y, Kwiatek A, Volpert OV. 2008. Thrombospondin and apoptosis: Molecular mechanisms and use for design of complementation treatments. Curr Drug Targets 9: 851-862.
    • (2008) Curr Drug Targets , vol.9 , pp. 851-862
    • Mirochnik, Y.1    Kwiatek, A.2    Volpert, O.V.3
  • 60
    • 0037277578 scopus 로고    scopus 로고
    • Role of nitric oxide in the modulation of angiogenesis
    • Morbidelli L, Donnini S, Ziche M. 2003. Role of nitric oxide in the modulation of angiogenesis. Curr Pharm Des 9: 521-530.
    • (2003) Curr Pharm Des , vol.9 , pp. 521-530
    • Morbidelli, L.1    Donnini, S.2    Ziche, M.3
  • 63
    • 56649123212 scopus 로고    scopus 로고
    • Risk of venous thromboembolism with the angiogenesis inhibitor bevacizumab in cancer patients: A meta-analysis
    • Nalluri SR, Chu D, Keresztes R, Zhu X, Wu S. 2008. Risk of venous thromboembolism with the angiogenesis inhibitor bevacizumab in cancer patients: A meta-analysis. JAMA 300: 2277-2285.
    • (2008) JAMA , vol.300 , pp. 2277-2285
    • Nalluri, S.R.1    Chu, D.2    Keresztes, R.3    Zhu, X.4    Wu, S.5
  • 64
    • 0028157338 scopus 로고
    • Matrix-bound thrombospondin promotes angiogenesis in vitro
    • Nicosia RF, Tuszynski GP. 1994. Matrix-bound thrombospondin promotes angiogenesis in vitro. J Cell Biol 124: 183-193.
    • (1994) J Cell Biol , vol.124 , pp. 183-193
    • Nicosia, R.F.1    Tuszynski, G.P.2
  • 65
    • 39449127385 scopus 로고    scopus 로고
    • Thrombospondins use the VLDL receptor and a nonapoptotic pathway to inhibit cell division in microvascular endothelial cells
    • Oganesian A, Armstrong LC, Migliorini MM, Strickland DK, Bornstein P. 2008. Thrombospondins use the VLDL receptor and a nonapoptotic pathway to inhibit cell division in microvascular endothelial cells. Mol Biol Cell 19: 563-571.
    • (2008) Mol Biol Cell , vol.19 , pp. 563-571
    • Oganesian, A.1    Armstrong, L.C.2    Migliorini, M.M.3    Strickland, D.K.4    Bornstein, P.5
  • 66
    • 48249112290 scopus 로고    scopus 로고
    • Improved vascular engraftment and graft function after inhibition of the angiostatic factor thrombospondin-1 in mouse pancreatic islets
    • Olerud J, Johansson M, Lawler J, Welsh N, Carlsson PO. 2008. Improved vascular engraftment and graft function after inhibition of the angiostatic factor thrombospondin-1 in mouse pancreatic islets. Diabetes 57: 1870-1877.
    • (2008) Diabetes , vol.57 , pp. 1870-1877
    • Olerud, J.1    Johansson, M.2    Lawler, J.3    Welsh, N.4    Carlsson, P.O.5
  • 67
    • 0029278614 scopus 로고
    • A marker-free method to estimate joint centre of rotation by video image processing
    • Persson T, Lanshammar H, Medved V. 1995. A marker-free method to estimate joint centre of rotation by video image processing. Comput Methods Programs Biomed 46: 217-224.
    • (1995) Comput Methods Programs Biomed , vol.46 , pp. 217-224
    • Persson, T.1    Lanshammar, H.2    Medved, V.3
  • 68
    • 26444476029 scopus 로고    scopus 로고
    • Identification of CD36 molecular features required for its in vitro angiostatic activity
    • Primo L, Ferrandi C, Roca C, Marchio S, di Blasio L, Alessio M, Bussolino F. 2005. Identification of CD36 molecular features required for its in vitro angiostatic activity. FASEB J 19: 1713-1715.
    • (2005) FASEB J , vol.19 , pp. 1713-1715
    • Primo, L.1    Ferrandi, C.2    Roca, C.3    Marchio, S.4    di Blasio, L.5    Alessio, M.6    Bussolino, F.7
  • 72
    • 33847414524 scopus 로고    scopus 로고
    • Nitric oxide and its gatekeeper thrombospondin-1 in tumor angiogenesis
    • Roberts DD, Isenberg JS, Ridnour LA, Wink DA. 2007. Nitric oxide and its gatekeeper thrombospondin-1 in tumor angiogenesis. Clin Cancer Res 13: 795-798.
    • (2007) Clin Cancer Res , vol.13 , pp. 795-798
    • Roberts, D.D.1    Isenberg, J.S.2    Ridnour, L.A.3    Wink, D.A.4
  • 73
    • 0035940429 scopus 로고    scopus 로고
    • Thrombospondin-1 suppresses spontaneous tumor growth and inhibits activation of matrix metalloproteinase-9 and mobilization of vascular endothelial growth factor
    • Rodriguez-Manzaneque JC, Lane TF, Ortega MA, Hynes RO, Lawler J, Iruela-Arispe ML. 2001. Thrombospondin-1 suppresses spontaneous tumor growth and inhibits activation of matrix metalloproteinase-9 and mobilization of vascular endothelial growth factor. Proc Natl Acad Sci 98: 12485-12490.
    • (2001) Proc Natl Acad Sci , vol.98 , pp. 12485-12490
    • Rodriguez-Manzaneque, J.C.1    Lane, T.F.2    Ortega, M.A.3    Hynes, R.O.4    Lawler, J.5    Iruela-Arispe, M.L.6
  • 75
    • 19944432454 scopus 로고    scopus 로고
    • Genetic heterogeneity of the vasculogenic phenotype parallels angiogenesis: Implications for cellular surrogate marker analysis of antiangiogenesis
    • Shaked Y, Bertolini F, Man S, Rogers MS, Cervi D, Foutz T, Rawn K, Voskas D, Dumont DJ, Ben-David Y, et al. 2005. Genetic heterogeneity of the vasculogenic phenotype parallels angiogenesis: Implications for cellular surrogate marker analysis of antiangiogenesis. Cancer Cell 7: 101-111.
    • (2005) Cancer Cell , vol.7 , pp. 101-111
    • Shaked, Y.1    Bertolini, F.2    Man, S.3    Rogers, M.S.4    Cervi, D.5    Foutz, T.6    Rawn, K.7    Voskas, D.8    Dumont, D.J.9    Ben-David, Y.10
  • 76
    • 13944267041 scopus 로고    scopus 로고
    • Inhibition of endothelial cell migration by thrombospondin-1 type-1 repeats is mediated by beta1 integrins
    • Short SM, Derrien A, Narsimhan RP, Lawler J, Ingber DE, Zetter BR. 2005. Inhibition of endothelial cell migration by thrombospondin-1 type-1 repeats is mediated by beta1 integrins. J Cell Biol 168: 643-653.
    • (2005) J Cell Biol , vol.168 , pp. 643-653
    • Short, S.M.1    Derrien, A.2    Narsimhan, R.P.3    Lawler, J.4    Ingber, D.E.5    Zetter, B.R.6
  • 77
    • 14644433781 scopus 로고    scopus 로고
    • The antiangiogenic effect of thrombospondin-2 is mediated by CD36 and modulated by histidine-rich glycoprotein
    • Simantov R, Febbraio M, Silverstein RL. 2005. The antiangiogenic effect of thrombospondin-2 is mediated by CD36 and modulated by histidine-rich glycoprotein. Matrix Biol 24: 27-34.
    • (2005) Matrix Biol , vol.24 , pp. 27-34
    • Simantov, R.1    Febbraio, M.2    Silverstein, R.L.3
  • 80
  • 81
    • 0025370524 scopus 로고
    • Platelet thrombospondin modulates endothelial cell adhesion, motility, and growth: A potential angiogenesis regulatory factor
    • Taraboletti G, Roberts D, Liotta LA, Giavazzi R. 1990. Platelet thrombospondin modulates endothelial cell adhesion, motility, and growth: A potential angiogenesis regulatory factor. J Cell Biol 111: 765-772.
    • (1990) J Cell Biol , vol.111 , pp. 765-772
    • Taraboletti, G.1    Roberts, D.2    Liotta, L.A.3    Giavazzi, R.4
  • 83
    • 3242772439 scopus 로고    scopus 로고
    • The thrombospondin type 1 repeat superfamily
    • Tucker RP. 2004. The thrombospondin type 1 repeat superfamily. Int J Biochem Cell Biol 36: 969-974.
    • (2004) Int J Biochem Cell Biol , vol.36 , pp. 969-974
    • Tucker, R.P.1
  • 85
    • 0036104828 scopus 로고    scopus 로고
    • Inducer-stimulated Fas targets activated endothelium for destruction by anti-angiogenic thrombospondin-1 and pigment epithelium-derived factor
    • Volpert OV, Zaichuk T, Zhou W, Reiher F, Ferguson TA, Stuart PM, Amin M, Bouck NP. 2002. Inducer-stimulated Fas targets activated endothelium for destruction by anti-angiogenic thrombospondin-1 and pigment epithelium-derived factor. Nat Med 8: 349-357.
    • (2002) Nat Med , vol.8 , pp. 349-357
    • Volpert, O.V.1    Zaichuk, T.2    Zhou, W.3    Reiher, F.4    Ferguson, T.A.5    Stuart, P.M.6    Amin, M.7    Bouck, N.P.8
  • 86
    • 13844292108 scopus 로고    scopus 로고
    • Internalization but not binding of thrombospondin-1 to low density lipoprotein receptor-related protein-1 requires heparan sulfate proteoglycans
    • Wang S, Herndon ME, Ranganathan S, Godyna S, Lawler J, Argraves WS, Liau G. 2004. Internalization but not binding of thrombospondin-1 to low density lipoprotein receptor-related protein-1 requires heparan sulfate proteoglycans. J Cell Biochem 91: 766-776.
    • (2004) J Cell Biochem , vol.91 , pp. 766-776
    • Wang, S.1    Herndon, M.E.2    Ranganathan, S.3    Godyna, S.4    Lawler, J.5    Argraves, W.S.6    Liau, G.7
  • 87
    • 33646922275 scopus 로고    scopus 로고
    • Enhanced proangiogenic signaling in thrombospondin-1-deficient retinal endothelial cells
    • Wang Y, Wang S, Sheibani N. 2006. Enhanced proangiogenic signaling in thrombospondin-1-deficient retinal endothelial cells. Microvasc Res 71: 143-151.
    • (2006) Microvasc Res , vol.71 , pp. 143-151
    • Wang, Y.1    Wang, S.2    Sheibani, N.3
  • 88
    • 34547768293 scopus 로고    scopus 로고
    • Novel antiangiogenic pathway of thrombospondin-1 mediated by suppression of the cell cycle
    • Yamauchi M, Imajoh-Ohmi S, Shibuya M. 2007. Novel antiangiogenic pathway of thrombospondin-1 mediated by suppression of the cell cycle. Cancer Sci 98: 1491-1497.
    • (2007) Cancer Sci , vol.98 , pp. 1491-1497
    • Yamauchi, M.1    Imajoh-Ohmi, S.2    Shibuya, M.3
  • 89
    • 25144488561 scopus 로고    scopus 로고
    • Metronomic low-dose chemotherapy boosts CD95-dependent antiangiogenic effect of the thrombospondin peptide ABT-510: A complementation antiangiogenic strategy
    • Yap R, Veliceasa D, Emmenegger U, Kerbel RS, McKay LM, Henkin J, VolpertOV. 2005. Metronomic low-dose chemotherapy boosts CD95-dependent antiangiogenic effect of the thrombospondin peptide ABT-510: A complementation antiangiogenic strategy. Clin Cancer Res 11: 6678-6685.
    • (2005) Clin Cancer Res , vol.11 , pp. 6678-6685
    • Yap, R.1    Veliceasa, D.2    Emmenegger, U.3    Kerbel, R.S.4    McKay, L.M.5    Henkin, J.6    Volpert, O.V.7
  • 92
    • 34548821303 scopus 로고    scopus 로고
    • Thrombospondin-based antiangiogenic therapy
    • Zhang X, Lawler J. 2007. Thrombospondin-based antiangiogenic therapy. Microvasc Res 74: 90-99.
    • (2007) Microvasc Res , vol.74 , pp. 90-99
    • Zhang, X.1    Lawler, J.2
  • 93
    • 16844380395 scopus 로고    scopus 로고
    • Antiangiogenic treatment with the three thrombospondin-1 type 1 repeats recombinant protein in an orthotopic human pancreatic cancer model
    • Zhang X, Galardi E, Duquette M, Delic M, Lawler J, Parangi S. 2005. Antiangiogenic treatment with the three thrombospondin-1 type 1 repeats recombinant protein in an orthotopic human pancreatic cancer model. Clin Cancer Res 11: 2337-2344.
    • (2005) Clin Cancer Res , vol.11 , pp. 2337-2344
    • Zhang, X.1    Galardi, E.2    Duquette, M.3    Delic, M.4    Lawler, J.5    Parangi, S.6
  • 94
    • 33845674173 scopus 로고    scopus 로고
    • Continuous administration of the three thrombospondin-1 type 1 repeats recombinant protein improves the potency of therapy in an orthotopic human pancreatic cancer model
    • Zhang X, Connolly C, Duquette M, Lawler J, Parangi S. 2007. Continuous administration of the three thrombospondin-1 type 1 repeats recombinant protein improves the potency of therapy in an orthotopic human pancreatic cancer model. Cancer Lett 247: 143-149.
    • (2007) Cancer Lett , vol.247 , pp. 143-149
    • Zhang, X.1    Connolly, C.2    Duquette, M.3    Lawler, J.4    Parangi, S.5


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