메뉴 건너뛰기




Volumn 10, Issue 10, 2014, Pages

Human Cytomegalovirus Drives Epigenetic Imprinting of the IFNG Locus in NKG2Chi Natural Killer Cells

Author keywords

[No Author keywords available]

Indexed keywords

CD57 ANTIGEN; GAMMA INTERFERON; GENOMIC DNA; CD56 ANTIGEN; KLRC2 PROTEIN, HUMAN; NATURAL KILLER CELL LECTIN LIKE RECEPTOR SUBFAMILY C;

EID: 84908348687     PISSN: 15537366     EISSN: 15537374     Source Type: Journal    
DOI: 10.1371/journal.ppat.1004441     Document Type: Article
Times cited : (203)

References (69)
  • 1
    • 0141924778 scopus 로고    scopus 로고
    • Constitutive cytokine mRNAs mark natural killer (NK) and NK T cells poised for rapid effector function
    • Stetson DB, Mohrs M, Reinhardt RL, Baron JL, Wang ZE, et al. (2003) Constitutive cytokine mRNAs mark natural killer (NK) and NK T cells poised for rapid effector function. J Exp Med 198: 1069–1076.
    • (2003) J Exp Med , vol.198 , pp. 1069-1076
    • Stetson, D.B.1    Mohrs, M.2    Reinhardt, R.L.3    Baron, J.L.4    Wang, Z.E.5
  • 2
    • 0036885067 scopus 로고    scopus 로고
    • The lineage decisions of helper T cells
    • Murphy KM, Reiner SL, (2002) The lineage decisions of helper T cells. Nat Rev Immunol 2: 933–944.
    • (2002) Nat Rev Immunol , vol.2 , pp. 933-944
    • Murphy, K.M.1    Reiner, S.L.2
  • 3
    • 58849092225 scopus 로고    scopus 로고
    • Epigenetic control of T-helper-cell differentiation
    • Wilson CB, Rowell E, Sekimata M, (2009) Epigenetic control of T-helper-cell differentiation. Nat Rev Immunol 9: 91–105.
    • (2009) Nat Rev Immunol , vol.9 , pp. 91-105
    • Wilson, C.B.1    Rowell, E.2    Sekimata, M.3
  • 4
    • 77958572323 scopus 로고    scopus 로고
    • Regulation of the Ifng locus in the context of T-lineage specification and plasticity
    • Balasubramani A, Mukasa R, Hatton RD, Weaver CT, (2010) Regulation of the Ifng locus in the context of T-lineage specification and plasticity. Immunol Rev 238: 216–232.
    • (2010) Immunol Rev , vol.238 , pp. 216-232
    • Balasubramani, A.1    Mukasa, R.2    Hatton, R.D.3    Weaver, C.T.4
  • 5
    • 1042278131 scopus 로고    scopus 로고
    • A distal enhancer in the interferon-gamma (IFN-gamma) locus revealed by genome sequence comparison
    • Lee DU, Avni O, Chen L, Rao A, (2004) A distal enhancer in the interferon-gamma (IFN-gamma) locus revealed by genome sequence comparison. J Biol Chem 279: 4802–4810.
    • (2004) J Biol Chem , vol.279 , pp. 4802-4810
    • Lee, D.U.1    Avni, O.2    Chen, L.3    Rao, A.4
  • 6
    • 4344574045 scopus 로고    scopus 로고
    • Evolutionarily conserved sequence elements that positively regulate IFN-gamma expression in T cells
    • Shnyreva M, Weaver WM, Blanchette M, Taylor SL, Tompa M, et al. (2004) Evolutionarily conserved sequence elements that positively regulate IFN-gamma expression in T cells. Proc Natl Acad Sci U S A 101: 12622–12627.
    • (2004) Proc Natl Acad Sci U S A , vol.101 , pp. 12622-12627
    • Shnyreva, M.1    Weaver, W.M.2    Blanchette, M.3    Taylor, S.L.4    Tompa, M.5
  • 7
    • 20644466433 scopus 로고    scopus 로고
    • NFAT proteins: key regulators of T-cell development and function
    • Macian F, (2005) NFAT proteins: key regulators of T-cell development and function. Nat Rev Immunol 5: 472–484.
    • (2005) Nat Rev Immunol , vol.5 , pp. 472-484
    • Macian, F.1
  • 8
    • 34250773899 scopus 로고    scopus 로고
    • Comprehensive epigenetic profiling identifies multiple distal regulatory elements directing transcription of the gene encoding interferon-gamma
    • Schoenborn JR, Dorschner MO, Sekimata M, Santer DM, Shnyreva M, et al. (2007) Comprehensive epigenetic profiling identifies multiple distal regulatory elements directing transcription of the gene encoding interferon-gamma. Nat Immunol 8: 732–742.
    • (2007) Nat Immunol , vol.8 , pp. 732-742
    • Schoenborn, J.R.1    Dorschner, M.O.2    Sekimata, M.3    Santer, D.M.4    Shnyreva, M.5
  • 9
    • 84875001418 scopus 로고    scopus 로고
    • Loss of methylation at the IFNG promoter and CNS-1 is associated with the development of functional IFN-gamma memory in human CD4(+) T lymphocytes
    • Dong J, Chang HD, Ivascu C, Qian Y, Rezai S, et al. (2013) Loss of methylation at the IFNG promoter and CNS-1 is associated with the development of functional IFN-gamma memory in human CD4(+) T lymphocytes. Eur J Immunol 43: 793–804.
    • (2013) Eur J Immunol , vol.43 , pp. 793-804
    • Dong, J.1    Chang, H.D.2    Ivascu, C.3    Qian, Y.4    Rezai, S.5
  • 10
    • 0032490674 scopus 로고    scopus 로고
    • Distinct methylation of the interferon gamma (IFN-gamma) and interleukin 3 (IL-3) genes in newly activated primary CD8+ T lymphocytes: regional IFN-gamma promoter demethylation and mRNA expression are heritable in CD44(high)CD8+ T cells
    • Fitzpatrick DR, Shirley KM, McDonald LE, Bielefeldt-Ohmann H, Kay GF, et al. (1998) Distinct methylation of the interferon gamma (IFN-gamma) and interleukin 3 (IL-3) genes in newly activated primary CD8+ T lymphocytes: regional IFN-gamma promoter demethylation and mRNA expression are heritable in CD44(high)CD8+ T cells. J Exp Med 188: 103–117.
    • (1998) J Exp Med , vol.188 , pp. 103-117
    • Fitzpatrick, D.R.1    Shirley, K.M.2    McDonald, L.E.3    Bielefeldt-Ohmann, H.4    Kay, G.F.5
  • 11
    • 28044433631 scopus 로고    scopus 로고
    • Histone hyperacetylated domains across the Ifng gene region in natural killer cells and T cells
    • Chang S, Aune TM, (2005) Histone hyperacetylated domains across the Ifng gene region in natural killer cells and T cells. Proc Natl Acad Sci U S A 102: 17095–17100.
    • (2005) Proc Natl Acad Sci U S A , vol.102 , pp. 17095-17100
    • Chang, S.1    Aune, T.M.2
  • 12
    • 3242771189 scopus 로고    scopus 로고
    • Cutting Edge: Innate production of IFN-gamma by NK cells is independent of epigenetic modification of the IFN-gamma promoter
    • Tato CM, Martins GA, High FA, DiCioccio CB, Reiner SL, et al. (2004) Cutting Edge: Innate production of IFN-gamma by NK cells is independent of epigenetic modification of the IFN-gamma promoter. J Immunol 173: 1514–1517.
    • (2004) J Immunol , vol.173 , pp. 1514-1517
    • Tato, C.M.1    Martins, G.A.2    High, F.A.3    Dicioccio, C.B.4    Reiner, S.L.5
  • 13
    • 33846208370 scopus 로고    scopus 로고
    • A distal conserved sequence element controls Ifng gene expression by T cells and NK cells
    • Hatton RD, Harrington LE, Luther RJ, Wakefield T, Janowski KM, et al. (2006) A distal conserved sequence element controls Ifng gene expression by T cells and NK cells. Immunity 25: 717–729.
    • (2006) Immunity , vol.25 , pp. 717-729
    • Hatton, R.D.1    Harrington, L.E.2    Luther, R.J.3    Wakefield, T.4    Janowski, K.M.5
  • 14
    • 84904389864 scopus 로고    scopus 로고
    • NK cells gain higher IFN-gamma competence during terminal differentiation
    • Luetke-Eversloh M, Cicek BB, Siracusa F, Thom JT, Hamann A, et al. (2014) NK cells gain higher IFN-gamma competence during terminal differentiation. Eur J Immunol 44: 2074–2084.
    • (2014) Eur J Immunol , vol.44 , pp. 2074-2084
    • Luetke-Eversloh, M.1    Cicek, B.B.2    Siracusa, F.3    Thom, J.T.4    Hamann, A.5
  • 15
    • 84884697357 scopus 로고    scopus 로고
    • Memory of infections: an emerging role for natural killer cells
    • Rolle A, Pollmann J, Cerwenka A, (2013) Memory of infections: an emerging role for natural killer cells. PLoS Pathog 9: e1003548.
    • (2013) PLoS Pathog , vol.9 , pp. e1003548
    • Rolle, A.1    Pollmann, J.2    Cerwenka, A.3
  • 16
    • 59049094662 scopus 로고    scopus 로고
    • Adaptive immune features of natural killer cells
    • Sun JC, Beilke JN, Lanier LL, (2009) Adaptive immune features of natural killer cells. Nature 457: 557–561.
    • (2009) Nature , vol.457 , pp. 557-561
    • Sun, J.C.1    Beilke, J.N.2    Lanier, L.L.3
  • 17
    • 33645989497 scopus 로고    scopus 로고
    • T cell- and B cell-independent adaptive immunity mediated by natural killer cells
    • O'Leary JG, Goodarzi M, Drayton DL, von Andrian UH, (2006) T cell- and B cell-independent adaptive immunity mediated by natural killer cells. Nat Immunol 7: 507–516.
    • (2006) Nat Immunol , vol.7 , pp. 507-516
    • O'leary, J.G.1    Goodarzi, M.2    Drayton, D.L.3    Von Andrian, U.H.4
  • 19
  • 20
    • 84872225254 scopus 로고    scopus 로고
    • Sustained effector function of IL-12/15/18-preactivated NK cells against established tumors
    • Ni J, Miller M, Stojanovic A, Garbi N, Cerwenka A, (2012) Sustained effector function of IL-12/15/18-preactivated NK cells against established tumors. J Exp Med 209: 2351–2365.
    • (2012) J Exp Med , vol.209 , pp. 2351-2365
    • Ni, J.1    Miller, M.2    Stojanovic, A.3    Garbi, N.4    Cerwenka, A.5
  • 21
    • 0034774942 scopus 로고    scopus 로고
    • Specific and nonspecific NK cell activation during virus infection
    • Dokun AO, Kim S, Smith HR, Kang HS, Chu DT, et al. (2001) Specific and nonspecific NK cell activation during virus infection. Nat Immunol 2: 951–956.
    • (2001) Nat Immunol , vol.2 , pp. 951-956
    • Dokun, A.O.1    Kim, S.2    Smith, H.R.3    Kang, H.S.4    Chu, D.T.5
  • 22
    • 84863804916 scopus 로고    scopus 로고
    • Proinflammatory cytokine signaling required for the generation of natural killer cell memory
    • Sun JC, Madera S, Bezman NA, Beilke JN, Kaplan MH, et al. (2012) Proinflammatory cytokine signaling required for the generation of natural killer cell memory. J Exp Med 209: 947–954.
    • (2012) J Exp Med , vol.209 , pp. 947-954
    • Sun, J.C.1    Madera, S.2    Bezman, N.A.3    Beilke, J.N.4    Kaplan, M.H.5
  • 23
    • 84894261203 scopus 로고    scopus 로고
    • Costimulatory molecule DNAM-1 is essential for optimal differentiation of memory natural killer cells during mouse cytomegalovirus infection
    • Nabekura T, Kanaya M, Shibuya A, Fu G, Gascoigne NR, et al. (2014) Costimulatory molecule DNAM-1 is essential for optimal differentiation of memory natural killer cells during mouse cytomegalovirus infection. Immunity 40: 225–234.
    • (2014) Immunity , vol.40 , pp. 225-234
    • Nabekura, T.1    Kanaya, M.2    Shibuya, A.3    Fu, G.4    Gascoigne, N.R.5
  • 24
    • 84901057914 scopus 로고    scopus 로고
    • The transcription factor Zbtb32 controls the proliferative burst of virus-specific natural killer cells responding to infection
    • Beaulieu AM, Zawislak CL, Nakayama T, Sun JC, (2014) The transcription factor Zbtb32 controls the proliferative burst of virus-specific natural killer cells responding to infection. Nat Immunol 15: 546–553.
    • (2014) Nat Immunol , vol.15 , pp. 546-553
    • Beaulieu, A.M.1    Zawislak, C.L.2    Nakayama, T.3    Sun, J.C.4
  • 25
    • 84903780487 scopus 로고    scopus 로고
    • Proapoptotic Bim regulates antigen-specific NK cell contraction and the generation of the memory NK cell pool after cytomegalovirus infection
    • Min-Oo G, Bezman NA, Madera S, Sun JC, Lanier LL, (2014) Proapoptotic Bim regulates antigen-specific NK cell contraction and the generation of the memory NK cell pool after cytomegalovirus infection. J Exp Med 211: 1289–1296.
    • (2014) J Exp Med , vol.211 , pp. 1289-1296
    • Min-Oo, G.1    Bezman, N.A.2    Madera, S.3    Sun, J.C.4    Lanier, L.L.5
  • 26
    • 84890828108 scopus 로고    scopus 로고
    • Nfil3-independent lineage maintenance and antiviral response of natural killer cells
    • Firth MA, Madera S, Beaulieu AM, Gasteiger G, Castillo EF, et al. (2013) Nfil3-independent lineage maintenance and antiviral response of natural killer cells. J Exp Med 210: 2981–2990.
    • (2013) J Exp Med , vol.210 , pp. 2981-2990
    • Firth, M.A.1    Madera, S.2    Beaulieu, A.M.3    Gasteiger, G.4    Castillo, E.F.5
  • 27
    • 84876868417 scopus 로고    scopus 로고
    • Stage-specific regulation of natural killer cell homeostasis and response against viral infection by microRNA-155
    • Zawislak CL, Beaulieu AM, Loeb GB, Karo J, Canner D, et al. (2013) Stage-specific regulation of natural killer cell homeostasis and response against viral infection by microRNA-155. Proc Natl Acad Sci U S A 110: 6967–6972.
    • (2013) Proc Natl Acad Sci U S A , vol.110 , pp. 6967-6972
    • Zawislak, C.L.1    Beaulieu, A.M.2    Loeb, G.B.3    Karo, J.4    Canner, D.5
  • 28
    • 9444273448 scopus 로고    scopus 로고
    • Imprint of human cytomegalovirus infection on the NK cell receptor repertoire
    • Guma M, Angulo A, Vilches C, Gomez-Lozano N, Malats N, et al. (2004) Imprint of human cytomegalovirus infection on the NK cell receptor repertoire. Blood 104: 3664–3671.
    • (2004) Blood , vol.104 , pp. 3664-3671
    • Guma, M.1    Angulo, A.2    Vilches, C.3    Gomez-Lozano, N.4    Malats, N.5
  • 29
    • 33646422721 scopus 로고    scopus 로고
    • Expansion of CD94/NKG2C+ NK cells in response to human cytomegalovirus-infected fibroblasts
    • Guma M, Budt M, Saez A, Brckalo T, Hengel H, et al. (2006) Expansion of CD94/NKG2C+ NK cells in response to human cytomegalovirus-infected fibroblasts. Blood 107: 3624–3631.
    • (2006) Blood , vol.107 , pp. 3624-3631
    • Guma, M.1    Budt, M.2    Saez, A.3    Brckalo, T.4    Hengel, H.5
  • 30
    • 84863338121 scopus 로고    scopus 로고
    • Cytomegalovirus reactivation after allogeneic transplantation promotes a lasting increase in educated NKG2C+ natural killer cells with potent function
    • Foley B, Cooley S, Verneris MR, Pitt M, Curtsinger J, et al. (2012) Cytomegalovirus reactivation after allogeneic transplantation promotes a lasting increase in educated NKG2C+ natural killer cells with potent function. Blood 119: 2665–2674.
    • (2012) Blood , vol.119 , pp. 2665-2674
    • Foley, B.1    Cooley, S.2    Verneris, M.R.3    Pitt, M.4    Curtsinger, J.5
  • 31
    • 80052602721 scopus 로고    scopus 로고
    • Expansion of a unique CD57(+)NKG2Chi natural killer cell subset during acute human cytomegalovirus infection
    • Lopez-Verges S, Milush JM, Schwartz BS, Pando MJ, Jarjoura J, et al. (2011) Expansion of a unique CD57(+)NKG2Chi natural killer cell subset during acute human cytomegalovirus infection. Proc Natl Acad Sci U S A 108: 14725–14732.
    • (2011) Proc Natl Acad Sci U S A , vol.108 , pp. 14725-14732
    • Lopez-Verges, S.1    Milush, J.M.2    Schwartz, B.S.3    Pando, M.J.4    Jarjoura, J.5
  • 32
    • 84868593211 scopus 로고    scopus 로고
    • Human cytomegalovirus (CMV)-induced memory-like NKG2C(+) NK cells are transplantable and expand in vivo in response to recipient CMV antigen
    • Foley B, Cooley S, Verneris MR, Curtsinger J, Luo X, et al. (2012) Human cytomegalovirus (CMV)-induced memory-like NKG2C(+) NK cells are transplantable and expand in vivo in response to recipient CMV antigen. J Immunol 189: 5082–5088.
    • (2012) J Immunol , vol.189 , pp. 5082-5088
    • Foley, B.1    Cooley, S.2    Verneris, M.R.3    Curtsinger, J.4    Luo, X.5
  • 33
  • 34
    • 84856055597 scopus 로고    scopus 로고
    • CMV drives clonal expansion of NKG2C+ NK cells expressing self-specific KIRs in chronic hepatitis patients
    • Beziat V, Dalgard O, Asselah T, Halfon P, Bedossa P, et al. (2012) CMV drives clonal expansion of NKG2C+ NK cells expressing self-specific KIRs in chronic hepatitis patients. Eur J Immunol 42: 447–457.
    • (2012) Eur J Immunol , vol.42 , pp. 447-457
    • Beziat, V.1    Dalgard, O.2    Asselah, T.3    Halfon, P.4    Bedossa, P.5
  • 36
    • 0032473478 scopus 로고    scopus 로고
    • Recognition of human histocompatibility leukocyte antigen (HLA)-E complexed with HLA class I signal sequence-derived peptides by CD94/NKG2 confers protection from natural killer cell-mediated lysis
    • Borrego F, Ulbrecht M, Weiss EH, Coligan JE, Brooks AG, (1998) Recognition of human histocompatibility leukocyte antigen (HLA)-E complexed with HLA class I signal sequence-derived peptides by CD94/NKG2 confers protection from natural killer cell-mediated lysis. J Exp Med 187: 813–818.
    • (1998) J Exp Med , vol.187 , pp. 813-818
    • Borrego, F.1    Ulbrecht, M.2    Weiss, E.H.3    Coligan, J.E.4    Brooks, A.G.5
  • 37
    • 0032574781 scopus 로고    scopus 로고
    • HLA-E is a major ligand for the natural killer inhibitory receptor CD94/NKG2A
    • Lee N, Llano M, Carretero M, Ishitani A, Navarro F, et al. (1998) HLA-E is a major ligand for the natural killer inhibitory receptor CD94/NKG2A. Proc Natl Acad Sci U S A 95: 5199–5204.
    • (1998) Proc Natl Acad Sci U S A , vol.95 , pp. 5199-5204
    • Lee, N.1    Llano, M.2    Carretero, M.3    Ishitani, A.4    Navarro, F.5
  • 38
    • 0030988540 scopus 로고    scopus 로고
    • The human major histocompatibility complex class Ib molecule HLA-E binds signal sequence-derived peptides with primary anchor residues at positions 2 and 9
    • Braud V, Jones EY, McMichael A, (1997) The human major histocompatibility complex class Ib molecule HLA-E binds signal sequence-derived peptides with primary anchor residues at positions 2 and 9. Eur J Immunol 27: 1164–1169.
    • (1997) Eur J Immunol , vol.27 , pp. 1164-1169
    • Braud, V.1    Jones, E.Y.2    McMichael, A.3
  • 39
    • 0032524965 scopus 로고    scopus 로고
    • HLA-E surface expression depends on binding of TAP-dependent peptides derived from certain HLA class I signal sequences
    • Lee N, Goodlett DR, Ishitani A, Marquardt H, Geraghty DE, (1998) HLA-E surface expression depends on binding of TAP-dependent peptides derived from certain HLA class I signal sequences. J Immunol 160: 4951–4960.
    • (1998) J Immunol , vol.160 , pp. 4951-4960
    • Lee, N.1    Goodlett, D.R.2    Ishitani, A.3    Marquardt, H.4    Geraghty, D.E.5
  • 40
    • 0034635414 scopus 로고    scopus 로고
    • Surface expression of HLA-E, an inhibitor of natural killer cells, enhanced by human cytomegalovirus gpUL40
    • Tomasec P, Braud VM, Rickards C, Powell MB, McSharry BP, et al. (2000) Surface expression of HLA-E, an inhibitor of natural killer cells, enhanced by human cytomegalovirus gpUL40. Science 287: 1031.
    • (2000) Science , vol.287 , pp. 1031
    • Tomasec, P.1    Braud, V.M.2    Rickards, C.3    Powell, M.B.4    McSharry, B.P.5
  • 41
    • 84875438461 scopus 로고    scopus 로고
    • Polymorphism in human cytomegalovirus UL40 impacts on recognition of human leukocyte antigen-E (HLA-E) by natural killer cells
    • Heatley SL, Pietra G, Lin J, Widjaja JM, Harpur CM, et al. (2013) Polymorphism in human cytomegalovirus UL40 impacts on recognition of human leukocyte antigen-E (HLA-E) by natural killer cells. J Biol Chem 288: 8679–8690.
    • (2013) J Biol Chem , vol.288 , pp. 8679-8690
    • Heatley, S.L.1    Pietra, G.2    Lin, J.3    Widjaja, J.M.4    Harpur, C.M.5
  • 42
    • 0032503029 scopus 로고    scopus 로고
    • Viral strategies of immune evasion
    • Ploegh HL, (1998) Viral strategies of immune evasion. Science 280: 248–253.
    • (1998) Science , vol.280 , pp. 248-253
    • Ploegh, H.L.1
  • 43
    • 0345583696 scopus 로고    scopus 로고
    • Kinetics and peptide dependency of the binding of the inhibitory NK receptor CD94/NKG2-A and the activating receptor CD94/NKG2-C to HLA-E
    • Vales-Gomez M, Reyburn HT, Erskine RA, Lopez-Botet M, Strominger JL, (1999) Kinetics and peptide dependency of the binding of the inhibitory NK receptor CD94/NKG2-A and the activating receptor CD94/NKG2-C to HLA-E. EMBO J 18: 4250–4260.
    • (1999) EMBO J , vol.18 , pp. 4250-4260
    • Vales-Gomez, M.1    Reyburn, H.T.2    Erskine, R.A.3    Lopez-Botet, M.4    Strominger, J.L.5
  • 44
    • 84876878182 scopus 로고    scopus 로고
    • NK cell responses to cytomegalovirus infection lead to stable imprints in the human KIR repertoire and involve activating KIRs
    • Beziat V, Liu LL, Malmberg JA, Ivarsson MA, Sohlberg E, et al. (2013) NK cell responses to cytomegalovirus infection lead to stable imprints in the human KIR repertoire and involve activating KIRs. Blood 121: 2678–2688.
    • (2013) Blood , vol.121 , pp. 2678-2688
    • Beziat, V.1    Liu, L.L.2    Malmberg, J.A.3    Ivarsson, M.A.4    Sohlberg, E.5
  • 45
    • 33847690322 scopus 로고    scopus 로고
    • Terminal differentiation of lymphocytes depends on Blimp-1
    • Kallies A, Nutt SL, (2007) Terminal differentiation of lymphocytes depends on Blimp-1. Curr Opin Immunol 19: 156–162.
    • (2007) Curr Opin Immunol , vol.19 , pp. 156-162
    • Kallies, A.1    Nutt, S.L.2
  • 46
    • 0042432046 scopus 로고    scopus 로고
    • CD8 T cell-specific downregulation of histone hyperacetylation and gene activation of the IL-4 gene locus by ROG, repressor of GATA
    • Omori M, Yamashita M, Inami M, Ukai-Tadenuma M, Kimura M, et al. (2003) CD8 T cell-specific downregulation of histone hyperacetylation and gene activation of the IL-4 gene locus by ROG, repressor of GATA. Immunity 19: 281–294.
    • (2003) Immunity , vol.19 , pp. 281-294
    • Omori, M.1    Yamashita, M.2    Inami, M.3    Ukai-Tadenuma, M.4    Kimura, M.5
  • 47
    • 0033696204 scopus 로고    scopus 로고
    • ROG, repressor of GATA, regulates the expression of cytokine genes
    • Miaw SC, Choi A, Yu E, Kishikawa H, Ho IC, (2000) ROG, repressor of GATA, regulates the expression of cytokine genes. Immunity 12: 323–333.
    • (2000) Immunity , vol.12 , pp. 323-333
    • Miaw, S.C.1    Choi, A.2    Yu, E.3    Kishikawa, H.4    Ho, I.C.5
  • 48
    • 38449102144 scopus 로고    scopus 로고
    • Functional analysis of promoter CpG methylation using a CpG-free luciferase reporter vector
    • Klug M, Rehli M, (2006) Functional analysis of promoter CpG methylation using a CpG-free luciferase reporter vector. Epigenetics 1: 127–130.
    • (2006) Epigenetics , vol.1 , pp. 127-130
    • Klug, M.1    Rehli, M.2
  • 49
    • 30144443832 scopus 로고    scopus 로고
    • Synergy among receptors on resting NK cells for the activation of natural cytotoxicity and cytokine secretion
    • Bryceson YT, March ME, Ljunggren HG, Long EO, (2006) Synergy among receptors on resting NK cells for the activation of natural cytotoxicity and cytokine secretion. Blood 107: 159–166.
    • (2006) Blood , vol.107 , pp. 159-166
    • Bryceson, Y.T.1    March, M.E.2    Ljunggren, H.G.3    Long, E.O.4
  • 51
    • 83655196758 scopus 로고    scopus 로고
    • Immune modulation during latent herpesvirus infection
    • White DW, Suzanne Beard R, Barton ES, (2012) Immune modulation during latent herpesvirus infection. Immunol Rev 245: 189–208.
    • (2012) Immunol Rev , vol.245 , pp. 189-208
    • White, D.W.1    Suzanne Beard, R.2    Barton, E.S.3
  • 52
    • 24344489044 scopus 로고    scopus 로고
    • Broadly targeted human cytomegalovirus-specific CD4+ and CD8+ T cells dominate the memory compartments of exposed subjects
    • Sylwester AW, Mitchell BL, Edgar JB, Taormina C, Pelte C, et al. (2005) Broadly targeted human cytomegalovirus-specific CD4+ and CD8+ T cells dominate the memory compartments of exposed subjects. J Exp Med 202: 673–685.
    • (2005) J Exp Med , vol.202 , pp. 673-685
    • Sylwester, A.W.1    Mitchell, B.L.2    Edgar, J.B.3    Taormina, C.4    Pelte, C.5
  • 53
    • 2542506189 scopus 로고    scopus 로고
    • CD8(+) T-cell immunity to cytomegalovirus
    • Moss P, Khan N, (2004) CD8(+) T-cell immunity to cytomegalovirus. Hum Immunol 65: 456–464.
    • (2004) Hum Immunol , vol.65 , pp. 456-464
    • Moss, P.1    Khan, N.2
  • 55
    • 78651492046 scopus 로고    scopus 로고
    • Rapid expansion and long-term persistence of elevated NK cell numbers in humans infected with hantavirus
    • Bjorkstrom NK, Lindgren T, Stoltz M, Fauriat C, Braun M, et al. (2011) Rapid expansion and long-term persistence of elevated NK cell numbers in humans infected with hantavirus. J Exp Med 208: 13–21.
    • (2011) J Exp Med , vol.208 , pp. 13-21
    • Bjorkstrom, N.K.1    Lindgren, T.2    Stoltz, M.3    Fauriat, C.4    Braun, M.5
  • 56
    • 80053440812 scopus 로고    scopus 로고
    • Unconventional repertoire profile is imprinted during acute chikungunya infection for natural killer cells polarization toward cytotoxicity
    • Petitdemange C, Becquart P, Wauquier N, Beziat V, Debre P, et al. (2011) Unconventional repertoire profile is imprinted during acute chikungunya infection for natural killer cells polarization toward cytotoxicity. PLoS Pathog 7: e1002268.
    • (2011) PLoS Pathog , vol.7 , pp. e1002268
    • Petitdemange, C.1    Becquart, P.2    Wauquier, N.3    Beziat, V.4    Debre, P.5
  • 57
    • 77958130545 scopus 로고    scopus 로고
    • Contribution of herpesvirus specific CD8 T cells to anti-viral T cell response in humans
    • Sandalova E, Laccabue D, Boni C, Tan AT, Fink K, et al. (2010) Contribution of herpesvirus specific CD8 T cells to anti-viral T cell response in humans. PLoS Pathog 6: e1001051.
    • (2010) PLoS Pathog , vol.6 , pp. e1001051
    • Sandalova, E.1    Laccabue, D.2    Boni, C.3    Tan, A.T.4    Fink, K.5
  • 59
    • 34548627666 scopus 로고    scopus 로고
    • Human CD8+ T cell memory generation in Puumala hantavirus infection occurs after the acute phase and is associated with boosting of EBV-specific CD8+ memory T cells
    • Tuuminen T, Kekalainen E, Makela S, Ala-Houhala I, Ennis FA, et al. (2007) Human CD8+ T cell memory generation in Puumala hantavirus infection occurs after the acute phase and is associated with boosting of EBV-specific CD8+ memory T cells. J Immunol 179: 1988–1995.
    • (2007) J Immunol , vol.179 , pp. 1988-1995
    • Tuuminen, T.1    Kekalainen, E.2    Makela, S.3    Ala-Houhala, I.4    Ennis, F.A.5
  • 60
    • 78149419031 scopus 로고    scopus 로고
    • Expression patterns of NKG2A, KIR, and CD57 define a process of CD56dim NK-cell differentiation uncoupled from NK-cell education
    • Bjorkstrom NK, Riese P, Heuts F, Andersson S, Fauriat C, et al. (2010) Expression patterns of NKG2A, KIR, and CD57 define a process of CD56dim NK-cell differentiation uncoupled from NK-cell education. Blood 116: 3853–3864.
    • (2010) Blood , vol.116 , pp. 3853-3864
    • Bjorkstrom, N.K.1    Riese, P.2    Heuts, F.3    Andersson, S.4    Fauriat, C.5
  • 61
    • 34250823515 scopus 로고    scopus 로고
    • Gene-specific control of inflammation by TLR-induced chromatin modifications
    • Foster SL, Hargreaves DC, Medzhitov R, (2007) Gene-specific control of inflammation by TLR-induced chromatin modifications. Nature 447: 972–978.
    • (2007) Nature , vol.447 , pp. 972-978
    • Foster, S.L.1    Hargreaves, D.C.2    Medzhitov, R.3
  • 62
    • 33751578866 scopus 로고    scopus 로고
    • TLR4-dependent NF-kappaB activation and mitogen- and stress-activated protein kinase 1-triggered phosphorylation events are central to Helicobacter pylori peptidyl prolyl cis-, trans-isomerase (HP0175)-mediated induction of IL-6 release from macrophages
    • Pathak SK, Basu S, Bhattacharyya A, Pathak S, Banerjee A, et al. (2006) TLR4-dependent NF-kappaB activation and mitogen- and stress-activated protein kinase 1-triggered phosphorylation events are central to Helicobacter pylori peptidyl prolyl cis-, trans-isomerase (HP0175)-mediated induction of IL-6 release from macrophages. J Immunol 177: 7950–7958.
    • (2006) J Immunol , vol.177 , pp. 7950-7958
    • Pathak, S.K.1    Basu, S.2    Bhattacharyya, A.3    Pathak, S.4    Banerjee, A.5
  • 64
    • 61849164458 scopus 로고    scopus 로고
    • Cytokine-induced human IFN-gamma-secreting effector-memory Th cells in chronic autoimmune inflammation
    • Sattler A, Wagner U, Rossol M, Sieper J, Wu P, et al. (2009) Cytokine-induced human IFN-gamma-secreting effector-memory Th cells in chronic autoimmune inflammation. Blood 113: 1948–1956.
    • (2009) Blood , vol.113 , pp. 1948-1956
    • Sattler, A.1    Wagner, U.2    Rossol, M.3    Sieper, J.4    Wu, P.5
  • 65
    • 84866860120 scopus 로고    scopus 로고
    • Gel-free multiplexed reduced representation bisulfite sequencing for large-scale DNA methylation profiling
    • Boyle P, Clement K, Gu H, Smith ZD, Ziller M, et al. (2012) Gel-free multiplexed reduced representation bisulfite sequencing for large-scale DNA methylation profiling. Genome Biol 13: R92.
    • (2012) Genome Biol , vol.13 , pp. R92
    • Boyle, P.1    Clement, K.2    Gu, H.3    Smith, Z.D.4    Ziller, M.5
  • 66
    • 80255127234 scopus 로고    scopus 로고
    • Cutadapt removes adapter sequences from high-throughput sequencing reads
    • Martin M, (2011) Cutadapt removes adapter sequences from high-throughput sequencing reads. EMBnetjournal 17: 10–12.
    • (2011) EMBnetjournal , vol.17 , pp. 10-12
    • Martin, M.1
  • 67
    • 77951820899 scopus 로고    scopus 로고
    • Fast and SNP-tolerant detection of complex variants and splicing in short reads
    • Wu TD, Nacu S, (2010) Fast and SNP-tolerant detection of complex variants and splicing in short reads. Bioinformatics 26: 873–881.
    • (2010) Bioinformatics , vol.26 , pp. 873-881
    • Wu, T.D.1    Nacu, S.2
  • 68
    • 84863565553 scopus 로고    scopus 로고
    • Bis-SNP: Combined DNA methylation and SNP calling for Bisulfite-seq data
    • Liu Y, Siegmund KD, Laird PW, Berman BP, (2012) Bis-SNP: Combined DNA methylation and SNP calling for Bisulfite-seq data. Genome Biol 13: R61.
    • (2012) Genome Biol , vol.13 , pp. R61
    • Liu, Y.1    Siegmund, K.D.2    Laird, P.W.3    Berman, B.P.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.