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Volumn 44, Issue 7, 2014, Pages 2074-2084

NK cells gain higher IFN-γ competence during terminal differentiation

Author keywords

Cell differentiation; Chromatin remodeling; IFN ; NK cells

Indexed keywords

CELL DIFFERENTIATION; CHROMATIN REMODELING; IFN-Γ; NK CELLS;

EID: 84904389864     PISSN: 00142980     EISSN: 15214141     Source Type: Journal    
DOI: 10.1002/eji.201344072     Document Type: Article
Times cited : (93)

References (57)
  • 1
    • 0036885067 scopus 로고    scopus 로고
    • The lineage decisions of helper T cells
    • Murphy, K. M. and Reiner, S. L., The lineage decisions of helper T cells. Nat. Rev. Immunol. 2002. 2: 933-944.
    • (2002) Nat. Rev. Immunol. , vol.2 , pp. 933-944
    • Murphy, K.M.1    Reiner, S.L.2
  • 2
    • 58849092225 scopus 로고    scopus 로고
    • Epigenetic control of T-helper-cell differentiation
    • Wilson, C. B., Rowell, E. and Sekimata, M., Epigenetic control of T-helper-cell differentiation. Nat. Rev. Immunol. 2009. 9: 91-105.
    • (2009) Nat. Rev. Immunol. , vol.9 , pp. 91-105
    • Wilson, C.B.1    Rowell, E.2    Sekimata, M.3
  • 5
    • 65549118531 scopus 로고    scopus 로고
    • Sequential polarization and imprinting of type 1 T helper lymphocytes by interferon-gamma and interleukin-12
    • Schulz, E. G., Mariani, L., Radbruch, A. and Hofer, T., Sequential polarization and imprinting of type 1 T helper lymphocytes by interferon-gamma and interleukin-12. Immunity 2009. 30: 673-683.
    • (2009) Immunity , vol.30 , pp. 673-683
    • Schulz, E.G.1    Mariani, L.2    Radbruch, A.3    Hofer, T.4
  • 6
    • 77954903767 scopus 로고    scopus 로고
    • Modular utilization of distal cis-regulatory elements controls Ifng gene expression in T cells activated by distinct stimuli
    • Balasubramani, A., Shibata, Y., Crawford, G. E., Baldwin, A. S., Hatton, R. D. and Weaver, C. T., Modular utilization of distal cis-regulatory elements controls Ifng gene expression in T cells activated by distinct stimuli. Immunity 2010. 33: 35-47.
    • (2010) Immunity , vol.33 , pp. 35-47
    • Balasubramani, A.1    Shibata, Y.2    Crawford, G.E.3    Baldwin, A.S.4    Hatton, R.D.5    Weaver, C.T.6
  • 7
    • 77958572323 scopus 로고    scopus 로고
    • Regulation of the Ifng locus in the context of T-lineage specification and plasticity
    • Balasubramani, A., Mukasa, R., Hatton, R. D. and Weaver, C. T., Regulation of the Ifng locus in the context of T-lineage specification and plasticity. Immunol. Rev. 2010. 238: 216-232.
    • (2010) Immunol. Rev. , vol.238 , pp. 216-232
    • Balasubramani, A.1    Mukasa, R.2    Hatton, R.D.3    Weaver, C.T.4
  • 8
    • 0032490674 scopus 로고    scopus 로고
    • Distinct methylation of the interferon gamma (IFN-gamma) and interleukin 3 (IL-3) genes in newly activated primary CD8+ T lymphocytes: regional IFN-gamma promoter demethylation and mRNA expression are heritable in CD44(high)CD8+ T cells
    • Fitzpatrick, D. R., Shirley, K. M., McDonald, L. E., Bielefeldt-Ohmann, H., Kay, G. F. and Kelso, A., Distinct methylation of the interferon gamma (IFN-gamma) and interleukin 3 (IL-3) genes in newly activated primary CD8+ T lymphocytes: regional IFN-gamma promoter demethylation and mRNA expression are heritable in CD44(high)CD8+ T cells. J. Exp. Med. 1998. 188: 103-117.
    • (1998) J. Exp. Med. , vol.188 , pp. 103-117
    • Fitzpatrick, D.R.1    Shirley, K.M.2    McDonald, L.E.3    Bielefeldt-Ohmann, H.4    Kay, G.F.5    Kelso, A.6
  • 9
    • 1442281449 scopus 로고    scopus 로고
    • Long-range histone acetylation of the Ifng gene is an essential feature of T cell differentiation
    • Zhou, W., Chang, S. and Aune, T. M., Long-range histone acetylation of the Ifng gene is an essential feature of T cell differentiation. Proc. Natl. Acad. Sci. USA 2004. 101: 2440-2445.
    • (2004) Proc. Natl. Acad. Sci. USA , vol.101 , pp. 2440-2445
    • Zhou, W.1    Chang, S.2    Aune, T.M.3
  • 10
    • 84875001418 scopus 로고    scopus 로고
    • Loss of methylation at the IFNG promoter and CNS-1 is associated with the development of functional IFN-gamma memory in human CD4(+) T lymphocytes
    • Dong, J., Chang, H. D., Ivascu, C., Qian, Y., Rezai, S., Okhrimenko, A., Cosmi, L. et al., Loss of methylation at the IFNG promoter and CNS-1 is associated with the development of functional IFN-gamma memory in human CD4(+) T lymphocytes. Eur. J. Immunol. 2013. 43: 793-804.
    • (2013) Eur. J. Immunol. , vol.43 , pp. 793-804
    • Dong, J.1    Chang, H.D.2    Ivascu, C.3    Qian, Y.4    Rezai, S.5    Okhrimenko, A.6    Cosmi, L.7
  • 12
    • 0141924778 scopus 로고    scopus 로고
    • Constitutive cytokine mRNAs mark natural killer (NK) and NK T cells poised for rapid effector function
    • Stetson, D. B., Mohrs, M., Reinhardt, R. L., Baron, J. L., Wang, Z. E., Gapin, L., Kronenberg, M. et al., Constitutive cytokine mRNAs mark natural killer (NK) and NK T cells poised for rapid effector function. J. Exp. Med. 2003. 198: 1069-1076.
    • (2003) J. Exp. Med. , vol.198 , pp. 1069-1076
    • Stetson, D.B.1    Mohrs, M.2    Reinhardt, R.L.3    Baron, J.L.4    Wang, Z.E.5    Gapin, L.6    Kronenberg, M.7
  • 13
    • 28044433631 scopus 로고    scopus 로고
    • Histone hyperacetylated domains across the Ifng gene region in natural killer cells and T cells
    • Chang, S. and Aune, T. M., Histone hyperacetylated domains across the Ifng gene region in natural killer cells and T cells. Proc. Natl. Acad. Sci. USA 2005. 102: 17095-17100.
    • (2005) Proc. Natl. Acad. Sci. USA , vol.102 , pp. 17095-17100
    • Chang, S.1    Aune, T.M.2
  • 14
    • 3242771189 scopus 로고    scopus 로고
    • Cutting edge: innate production of IFN-gamma by NK cells is independent of epigenetic modification of the IFN-gamma promoter
    • Tato, C. M., Martins, G. A., High, F. A., DiCioccio, C. B., Reiner, S. L. and Hunter, C. A., Cutting edge: innate production of IFN-gamma by NK cells is independent of epigenetic modification of the IFN-gamma promoter. J. Immunol. 2004. 173: 1514-1517.
    • (2004) J. Immunol. , vol.173 , pp. 1514-1517
    • Tato, C.M.1    Martins, G.A.2    High, F.A.3    DiCioccio, C.B.4    Reiner, S.L.5    Hunter, C.A.6
  • 16
    • 50949124847 scopus 로고    scopus 로고
    • Human natural killer cells
    • Caligiuri, M. A., Human natural killer cells. Blood 2008. 112: 461-469.
    • (2008) Blood , vol.112 , pp. 461-469
    • Caligiuri, M.A.1
  • 17
    • 30144443832 scopus 로고    scopus 로고
    • Synergy among receptors on resting NK cells for the activation of natural cytotoxicity and cytokine secretion
    • Bryceson, Y. T., March, M. E., Ljunggren, H. G. and Long, E. O., Synergy among receptors on resting NK cells for the activation of natural cytotoxicity and cytokine secretion. Blood 2006. 107: 159-166.
    • (2006) Blood , vol.107 , pp. 159-166
    • Bryceson, Y.T.1    March, M.E.2    Ljunggren, H.G.3    Long, E.O.4
  • 19
    • 66449134616 scopus 로고    scopus 로고
    • NCRs and DNAM-1 mediate NK cell recognition and lysis of human and mouse melanoma cell lines in vitro and in vivo
    • Lakshmikanth, T., Burke, S., Ali, T. H., Kimpfler, S., Ursini, F., Ruggeri, L., Capanni, M. et al., NCRs and DNAM-1 mediate NK cell recognition and lysis of human and mouse melanoma cell lines in vitro and in vivo. J. Clin. Invest. 2009. 119: 1251-1263.
    • (2009) J. Clin. Invest. , vol.119 , pp. 1251-1263
    • Lakshmikanth, T.1    Burke, S.2    Ali, T.H.3    Kimpfler, S.4    Ursini, F.5    Ruggeri, L.6    Capanni, M.7
  • 20
    • 20144385362 scopus 로고    scopus 로고
    • Analysis of the receptor-ligand interactions in the natural killer-mediated lysis of freshly isolated myeloid or lymphoblastic leukemias: evidence for the involvement of the Poliovirus receptor (CD155) and Nectin-2 (CD112)
    • Pende, D., Spaggiari, G. M., Marcenaro, S., Martini, S., Rivera, P., Capobianco, A., Falco, M. et al., Analysis of the receptor-ligand interactions in the natural killer-mediated lysis of freshly isolated myeloid or lymphoblastic leukemias: evidence for the involvement of the Poliovirus receptor (CD155) and Nectin-2 (CD112). Blood 2005. 105: 2066-2073.
    • (2005) Blood , vol.105 , pp. 2066-2073
    • Pende, D.1    Spaggiari, G.M.2    Marcenaro, S.3    Martini, S.4    Rivera, P.5    Capobianco, A.6    Falco, M.7
  • 21
    • 77950408682 scopus 로고    scopus 로고
    • Regulation of human NK-cell cytokine and chemokine production by target cell recognition
    • Fauriat, C., Long, E. O., Ljunggren, H. G. and Bryceson, Y. T., Regulation of human NK-cell cytokine and chemokine production by target cell recognition. Blood 2010. 115: 2167-2176.
    • (2010) Blood , vol.115 , pp. 2167-2176
    • Fauriat, C.1    Long, E.O.2    Ljunggren, H.G.3    Bryceson, Y.T.4
  • 22
    • 33750686595 scopus 로고    scopus 로고
    • Human natural killer cell development
    • Freud, A. G. and Caligiuri, M. A., Human natural killer cell development. Immunol. Rev. 2006. 214: 56-72.
    • (2006) Immunol. Rev. , vol.214 , pp. 56-72
    • Freud, A.G.1    Caligiuri, M.A.2
  • 24
    • 0022589079 scopus 로고
    • The relationship of CD16 (Leu-11) and Leu-19 (NKH-1) antigen expression on human peripheral blood NK cells and cytotoxic T lymphocytes
    • Lanier, L. L., Le, A. M., Civin, C. I., Loken, M. R. and Phillips, J. H., The relationship of CD16 (Leu-11) and Leu-19 (NKH-1) antigen expression on human peripheral blood NK cells and cytotoxic T lymphocytes. J. Immunol. 1986. 136: 4480-4486.
    • (1986) J. Immunol. , vol.136 , pp. 4480-4486
    • Lanier, L.L.1    Le, A.M.2    Civin, C.I.3    Loken, M.R.4    Phillips, J.H.5
  • 25
    • 0035874522 scopus 로고    scopus 로고
    • Human natural killer cells: a unique innate immunoregulatory role for the CD56(bright) subset
    • Cooper, M. A., Fehniger, T. A., Turner, S. C., Chen, K. S., Ghaheri, B. A., Ghayur, T., Carson, W. E. et al., Human natural killer cells: a unique innate immunoregulatory role for the CD56(bright) subset. Blood 2001. 97: 3146-3151.
    • (2001) Blood , vol.97 , pp. 3146-3151
    • Cooper, M.A.1    Fehniger, T.A.2    Turner, S.C.3    Chen, K.S.4    Ghaheri, B.A.5    Ghayur, T.6    Carson, W.E.7
  • 27
    • 78149439385 scopus 로고    scopus 로고
    • CD57 defines a functionally distinct population of mature NK cells in the human CD56dimCD16+ NK-cell subset
    • Lopez-Verges, S., Milush, J. M., Pandey, S., York, V. A., Arakawa-Hoyt, J., Pircher, H., Norris, P. J. et al., CD57 defines a functionally distinct population of mature NK cells in the human CD56dimCD16+ NK-cell subset. Blood 2010. 116: 3865-3874.
    • (2010) Blood , vol.116 , pp. 3865-3874
    • Lopez-Verges, S.1    Milush, J.M.2    Pandey, S.3    York, V.A.4    Arakawa-Hoyt, J.5    Pircher, H.6    Norris, P.J.7
  • 28
    • 78149419031 scopus 로고    scopus 로고
    • Expression patterns of NKG2A, KIR, and CD57 define a process of CD56dim NK-cell differentiation uncoupled from NK-cell education
    • Bjorkstrom, N. K., Riese, P., Heuts, F., Andersson, S., Fauriat, C., Ivarsson, M. A., Bjorklund, A. T. et al., Expression patterns of NKG2A, KIR, and CD57 define a process of CD56dim NK-cell differentiation uncoupled from NK-cell education. Blood 2010. 116: 3853-3864.
    • (2010) Blood , vol.116 , pp. 3853-3864
    • Bjorkstrom, N.K.1    Riese, P.2    Heuts, F.3    Andersson, S.4    Fauriat, C.5    Ivarsson, M.A.6    Bjorklund, A.T.7
  • 29
    • 77957779206 scopus 로고    scopus 로고
    • NK cell terminal differentiation: correlated stepwise decrease of NKG2A and acquisition of KIRs
    • Beziat, V., Descours, B., Parizot, C., Debre, P. and Vieillard, V., NK cell terminal differentiation: correlated stepwise decrease of NKG2A and acquisition of KIRs. PLoS One 2010. 5: e11966.
    • (2010) PLoS One , vol.5
    • Beziat, V.1    Descours, B.2    Parizot, C.3    Debre, P.4    Vieillard, V.5
  • 32
    • 60549117539 scopus 로고    scopus 로고
    • IL-15 trans-presentation promotes human NK cell development and differentiation in vivo
    • Huntington, N. D., Legrand, N., Alves, N. L., Jaron, B., Weijer, K., Plet, A., Corcuff, E. et al., IL-15 trans-presentation promotes human NK cell development and differentiation in vivo. J. Exp. Med. 2009. 206: 25-34.
    • (2009) J. Exp. Med. , vol.206 , pp. 25-34
    • Huntington, N.D.1    Legrand, N.2    Alves, N.L.3    Jaron, B.4    Weijer, K.5    Plet, A.6    Corcuff, E.7
  • 33
    • 0035499063 scopus 로고    scopus 로고
    • The biology of human natural killer-cell subsets
    • Cooper, M. A., Fehniger, T. A. and Caligiuri, M. A., The biology of human natural killer-cell subsets. Trends Immunol. 2001. 22: 633-640.
    • (2001) Trends Immunol. , vol.22 , pp. 633-640
    • Cooper, M.A.1    Fehniger, T.A.2    Caligiuri, M.A.3
  • 34
    • 33745567831 scopus 로고    scopus 로고
    • Self-tolerance of natural killer cells
    • Raulet, D. H. and Vance, R. E., Self-tolerance of natural killer cells. Nat. Rev. Immunol. 2006. 6: 520-531.
    • (2006) Nat. Rev. Immunol. , vol.6 , pp. 520-531
    • Raulet, D.H.1    Vance, R.E.2
  • 35
    • 33750735022 scopus 로고    scopus 로고
    • Licensing of natural killer cells by self-major histocompatibility complex class I
    • Yokoyama, W. M. and Kim, S., Licensing of natural killer cells by self-major histocompatibility complex class I. Immunol. Rev. 2006. 214: 143-154.
    • (2006) Immunol. Rev. , vol.214 , pp. 143-154
    • Yokoyama, W.M.1    Kim, S.2
  • 37
    • 79960914933 scopus 로고    scopus 로고
    • Unifying concepts of MHC-dependent natural killer cell education
    • Elliott, J. M. and Yokoyama, W. M., Unifying concepts of MHC-dependent natural killer cell education. Trends Immunol. 2011. 32: 364-372.
    • (2011) Trends Immunol. , vol.32 , pp. 364-372
    • Elliott, J.M.1    Yokoyama, W.M.2
  • 38
    • 61949439062 scopus 로고    scopus 로고
    • A role for cis interaction between the inhibitory Ly49A receptor and MHC class I for natural killer cell education
    • Chalifour, A., Scarpellino, L., Back, J., Brodin, P., Devevre, E., Gros, F., Levy, F. et al., A role for cis interaction between the inhibitory Ly49A receptor and MHC class I for natural killer cell education. Immunity 2009. 30: 337-347.
    • (2009) Immunity , vol.30 , pp. 337-347
    • Chalifour, A.1    Scarpellino, L.2    Back, J.3    Brodin, P.4    Devevre, E.5    Gros, F.6    Levy, F.7
  • 39
    • 79953840956 scopus 로고    scopus 로고
    • Confinement of activating receptors at the plasma membrane controls natural killer cell tolerance
    • Guia, S., Jaeger, B. N., Piatek, S., Mailfert, S., Trombik, T., Fenis, A., Chevrier, N. et al., Confinement of activating receptors at the plasma membrane controls natural killer cell tolerance. Sci. Signal. 2011. 4: ra21.
    • (2011) Sci. Signal. , vol.4
    • Guia, S.1    Jaeger, B.N.2    Piatek, S.3    Mailfert, S.4    Trombik, T.5    Fenis, A.6    Chevrier, N.7
  • 40
    • 79951470129 scopus 로고    scopus 로고
    • A role for Blimp1 in the transcriptional network controlling natural killer cell maturation
    • Kallies, A., Carotta, S., Huntington, N. D., Bernard, N. J., Tarlinton, D. M., Smyth, M. J. and Nutt, S. L., A role for Blimp1 in the transcriptional network controlling natural killer cell maturation. Blood 2011. 117: 1869-1879.
    • (2011) Blood , vol.117 , pp. 1869-1879
    • Kallies, A.1    Carotta, S.2    Huntington, N.D.3    Bernard, N.J.4    Tarlinton, D.M.5    Smyth, M.J.6    Nutt, S.L.7
  • 41
    • 9144233578 scopus 로고    scopus 로고
    • Novel insights on human NK cells' immunological modalities revealed by gene expression profiling
    • Hanna, J., Bechtel, P., Zhai, Y., Youssef, F., McLachlan, K. and Mandelboim, O., Novel insights on human NK cells' immunological modalities revealed by gene expression profiling. J. Immunol. 2004. 173: 6547-6563.
    • (2004) J. Immunol. , vol.173 , pp. 6547-6563
    • Hanna, J.1    Bechtel, P.2    Zhai, Y.3    Youssef, F.4    McLachlan, K.5    Mandelboim, O.6
  • 42
    • 0034677646 scopus 로고    scopus 로고
    • A novel transcription factor, T-bet, directs Th1 lineage commitment
    • Szabo, S. J., Kim, S. T., Costa, G. L., Zhang, X., Fathman, C. G. and Glimcher, L. H., A novel transcription factor, T-bet, directs Th1 lineage commitment. Cell 2000. 100: 655-669.
    • (2000) Cell , vol.100 , pp. 655-669
    • Szabo, S.J.1    Kim, S.T.2    Costa, G.L.3    Zhang, X.4    Fathman, C.G.5    Glimcher, L.H.6
  • 44
    • 33846489173 scopus 로고    scopus 로고
    • Transcription factors T-bet and Runx3 cooperate to activate Ifng and silence Il4 in T helper type 1 cells
    • Djuretic, I. M., Levanon, D., Negreanu, V., Groner, Y., Rao, A. and Ansel, K. M., Transcription factors T-bet and Runx3 cooperate to activate Ifng and silence Il4 in T helper type 1 cells. Nat. Immunol. 2007. 8: 145-153.
    • (2007) Nat. Immunol. , vol.8 , pp. 145-153
    • Djuretic, I.M.1    Levanon, D.2    Negreanu, V.3    Groner, Y.4    Rao, A.5    Ansel, K.M.6
  • 45
    • 0036301997 scopus 로고    scopus 로고
    • Hlx is induced by and genetically interacts with T-bet to promote heritable T(H)1 gene induction
    • Mullen, A. C., Hutchins, A. S., High, F. A., Lee, H. W., Sykes, K. J., Chodosh, L. A. and Reiner, S. L., Hlx is induced by and genetically interacts with T-bet to promote heritable T(H)1 gene induction. Nat. Immunol. 2002. 3: 652-658.
    • (2002) Nat. Immunol. , vol.3 , pp. 652-658
    • Mullen, A.C.1    Hutchins, A.S.2    High, F.A.3    Lee, H.W.4    Sykes, K.J.5    Chodosh, L.A.6    Reiner, S.L.7
  • 46
    • 34250773899 scopus 로고    scopus 로고
    • Comprehensive epigenetic profiling identifies multiple distal regulatory elements directing transcription of the gene encoding interferon-gamma
    • Schoenborn, J. R., Dorschner, M. O., Sekimata, M., Santer, D. M., Shnyreva, M., Fitzpatrick, D. R., Stamatoyannopoulos, J. A. et al., Comprehensive epigenetic profiling identifies multiple distal regulatory elements directing transcription of the gene encoding interferon-gamma. Nat. Immunol. 2007. 8: 732-742.
    • (2007) Nat. Immunol. , vol.8 , pp. 732-742
    • Schoenborn, J.R.1    Dorschner, M.O.2    Sekimata, M.3    Santer, D.M.4    Shnyreva, M.5    Fitzpatrick, D.R.6    Stamatoyannopoulos, J.A.7
  • 47
    • 38449102144 scopus 로고    scopus 로고
    • Functional analysis of promoter CpG methylation using a CpG-free luciferase reporter vector
    • Klug, M. and Rehli, M., Functional analysis of promoter CpG methylation using a CpG-free luciferase reporter vector. Epigenetics 2006. 1: 127-130.
    • (2006) Epigenetics , vol.1 , pp. 127-130
    • Klug, M.1    Rehli, M.2
  • 49
    • 77951649964 scopus 로고    scopus 로고
    • Effects of MHC class I alleles on licensing of Ly49A+ NK cells
    • Jonsson, A. H., Yang, L., Kim, S., Taffner, S. M. and Yokoyama, W. M., Effects of MHC class I alleles on licensing of Ly49A+ NK cells. J. Immunol. 2010. 184: 3424-3432.
    • (2010) J. Immunol. , vol.184 , pp. 3424-3432
    • Jonsson, A.H.1    Yang, L.2    Kim, S.3    Taffner, S.M.4    Yokoyama, W.M.5
  • 50
    • 33745753087 scopus 로고    scopus 로고
    • Inhibition of IFN-gamma transcription by site-specific methylation during T helper cell development
    • Jones, B. and Chen, J., Inhibition of IFN-gamma transcription by site-specific methylation during T helper cell development. EMBO J. 2006. 25: 2443-2452.
    • (2006) EMBO J. , vol.25 , pp. 2443-2452
    • Jones, B.1    Chen, J.2
  • 52
    • 0032567436 scopus 로고    scopus 로고
    • The roles of nuclear factor of activated T cells and ying-yang 1 in activation-induced expression of the interferon-gamma promoter in T cells
    • Sweetser, M. T., Hoey, T., Sun, Y. L., Weaver, W. M., Price, G. A. and Wilson, C. B., The roles of nuclear factor of activated T cells and ying-yang 1 in activation-induced expression of the interferon-gamma promoter in T cells. J. Biol. Chem. 1998. 273: 34775-34783.
    • (1998) J. Biol. Chem. , vol.273 , pp. 34775-34783
    • Sweetser, M.T.1    Hoey, T.2    Sun, Y.L.3    Weaver, W.M.4    Price, G.A.5    Wilson, C.B.6
  • 53
    • 0029732843 scopus 로고    scopus 로고
    • The proximal regulatory element of the interferon-gamma promoter mediates selective expression in T cells
    • Penix, L. A., Sweetser, M. T., Weaver, W. M., Hoeffler, J. P., Kerppola, T. K. and Wilson, C. B., The proximal regulatory element of the interferon-gamma promoter mediates selective expression in T cells. J. Biol. Chem. 1996. 271: 31964-31972.
    • (1996) J. Biol. Chem. , vol.271 , pp. 31964-31972
    • Penix, L.A.1    Sweetser, M.T.2    Weaver, W.M.3    Hoeffler, J.P.4    Kerppola, T.K.5    Wilson, C.B.6
  • 54
    • 84883670186 scopus 로고    scopus 로고
    • Epigenetic regulation of NK cell differentiation and effector functions
    • Cichocki, F., Miller, J. S., Anderson, S. K. and Bryceson, Y. T., Epigenetic regulation of NK cell differentiation and effector functions. Front Immunol. 2013. 4: 55.
    • (2013) Front Immunol. , vol.4 , pp. 55
    • Cichocki, F.1    Miller, J.S.2    Anderson, S.K.3    Bryceson, Y.T.4
  • 55
  • 57
    • 61849164458 scopus 로고    scopus 로고
    • Cytokine-induced human IFN-gamma-secreting effector-memory Th cells in chronic autoimmune inflammation
    • Sattler, A., Wagner, U., Rossol, M., Sieper, J., Wu, P., Krause, A., Schmidt et al., Cytokine-induced human IFN-gamma-secreting effector-memory Th cells in chronic autoimmune inflammation. Blood 2009. 113: 1948-1956.
    • (2009) Blood , vol.113 , pp. 1948-1956
    • Sattler, A.1    Wagner, U.2    Rossol, M.3    Sieper, J.4    Wu, P.5    Krause, A.6    Schmidt, W.A.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.