Paeonol pretreatment attenuates cerebral ischemic injury via upregulating expression of pAkt, Nrf2, HO-1 and ameliorating BBB permeability in mice

Brain Research Bulletin

Volumn 109, Issue , 2014, Pages 61-67

  Zhao, Yuan ^a   Fu, Baosheng ^a   Zhang, Xiangjian ^a,b,c   Zhao, Ting ^a   Chen, Linyu ^a,b,c   Zhang, Jian ^a,b,c   Wang, Xiaolu ^b  

^a HEBEI MEDICAL UNIVERSITY   (China)

^b Hebei Collaborative Innovation Center for Cerebrovascular Disease   (China)

^c Hebei Key Laboratory for Neurology   (China)

Author keywords

Claudin 5; HO 1; Ischemic stroke; Nrf2; Paeonol; PAkt

Indexed keywords

CLAUDIN 5; HEME OXYGENASE 1; MALONALDEHYDE; PEONOL; PROTEIN KINASE B; SUPEROXIDE DISMUTASE; TRANSCRIPTION FACTOR NRF2; ACETOPHENONE DERIVATIVE; NEUROPROTECTIVE AGENT; NFE2L2 PROTEIN, MOUSE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD BRAIN BARRIER; BRAIN INFARCTION SIZE; BRAIN ISCHEMIA; BRAIN WATER; CONTROLLED STUDY; MIDDLE CEREBRAL ARTERY OCCLUSION; NEUROLOGICAL DEFICIT SCORE; NONHUMAN; PROTEIN EXPRESSION; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SCORING SYSTEM; UPREGULATION; WESTERN BLOTTING; ANIMAL; CAPILLARY PERMEABILITY; DISEASE MODEL; DRUG EFFECTS; GENETICS; INFARCTION, MIDDLE CEREBRAL ARTERY; INSTITUTE FOR CANCER RESEARCH MOUSE; MALE; METABOLISM; MOUSE; SPECTROSCOPY;

ACETOPHENONES; ANIMALS; BLOOD-BRAIN BARRIER; CAPILLARY PERMEABILITY; CLAUDIN-5; DISEASE MODELS, ANIMAL; HEME OXYGENASE-1; INFARCTION, MIDDLE CEREBRAL ARTERY; MALE; MALONDIALDEHYDE; MICE; MICE, INBRED ICR; NEUROPROTECTIVE AGENTS; NF-E2-RELATED FACTOR 2; PROTO-ONCOGENE PROTEINS C-AKT; SPECTRUM ANALYSIS; SUPEROXIDE DISMUTASE; UP-REGULATION;

EID: 84908326764     PISSN: 03619230     EISSN: 18732747     Source Type: Journal    
DOI: 10.1016/j.brainresbull.2014.09.008     Document Type: Article

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