메뉴 건너뛰기




Volumn 39, Issue 6, 2014, Pages 407-416

Metabotropic glutamate receptor mGluR2/3 and mGluR5 binding in the anterior cingulate cortex in psychotic and nonpsychotic depression, bipolar disorder and schizophrenia: Implications for novel mGluR-based therapeutics

Author keywords

[No Author keywords available]

Indexed keywords

2 AMINO 2 (2 CARBOXYCYCLOPROPYL) 3 (XANTHEN 9 YL) PROPIONIC ACID; 2 METHYL 6 (PHENYLETHYNYL) PYRIDINE; METABOTROPIC RECEPTOR; METABOTROPIC RECEPTOR 2; METABOTROPIC RECEPTOR 3; METABOTROPIC RECEPTOR 5; UNCLASSIFIED DRUG; GRM5 PROTEIN, HUMAN;

EID: 84908271476     PISSN: 11804882     EISSN: 14882434     Source Type: Journal    
DOI: 10.1503/jpn.130242     Document Type: Article
Times cited : (58)

References (47)
  • 1
    • 84855545792 scopus 로고    scopus 로고
    • Novel glutamatergic agents for major depressive disorder and bipolar disorder
    • Machado-Vieira R, Ibrahim L, Henter ID, et al. Novel glutamatergic agents for major depressive disorder and bipolar disorder. Pharmacol Biochem Behav 2012;100:678-87.
    • (2012) Pharmacol Biochem Behav , vol.100 , pp. 678-687
    • McHado-Vieira, R.1    Ibrahim, L.2    Henter, I.D.3
  • 2
    • 84879375571 scopus 로고    scopus 로고
    • Challenges in the treatment of major depressive disorder with psychotic features
    • Rothschild AJ. Challenges in the treatment of major depressive disorder with psychotic features. Schizophr Bull 2013;39:787-96.
    • (2013) Schizophr Bull , vol.39 , pp. 787-796
    • Rothschild, A.J.1
  • 3
    • 84873108695 scopus 로고    scopus 로고
    • Localization of function in anterior cingulate cortex: From psychosurgery to functional neuroimaging
    • Gasquoine PG. Localization of function in anterior cingulate cortex: From psychosurgery to functional neuroimaging. Neurosci Biobehav Rev 2013;37:340-8.
    • (2013) Neurosci Biobehav Rev , vol.37 , pp. 340-348
    • Gasquoine, P.G.1
  • 4
    • 0342546475 scopus 로고    scopus 로고
    • Reduced glutamate in the anterior cingulate cortex in depression: An in vivo proton magnetic resonance spectroscopy study
    • Auer DP, Pütz B, Kraft E, et al. Reduced glutamate in the anterior cingulate cortex in depression: an in vivo proton magnetic resonance spectroscopy study. Biol Psychiatry 2000;47:305-13.
    • (2000) Biol Psychiatry , vol.47 , pp. 305-313
    • Auer, D.P.1    Pütz, B.2    Kraft, E.3
  • 5
    • 35848939420 scopus 로고    scopus 로고
    • Increased levels of glutamate in brains from patients with mood disorders
    • Hashimoto K, Sawa A, Iyo M. Increased levels of glutamate in brains from patients with mood disorders. Biol Psychiatry 2007;62:1310-6.
    • (2007) Biol Psychiatry , vol.62 , pp. 1310-1316
    • Hashimoto, K.1    Sawa, A.2    Iyo, M.3
  • 6
    • 7244220611 scopus 로고    scopus 로고
    • Glutamate and glutamine in the anterior cingulate and thalamus of medicated patients with chronic schizophrenia and healthy comparison subjects measured with 4.0-T proton MRS
    • Théberge J, Al-Semaan Y, Williamson PC, et al. Glutamate and glutamine in the anterior cingulate and thalamus of medicated patients with chronic schizophrenia and healthy comparison subjects measured with 4.0-T proton MRS. Am J Psychiatry 2003;160:2231-3.
    • (2003) Am J Psychiatry , vol.160 , pp. 2231-2233
    • Théberge, J.1    Al-Semaan, Y.2    Williamson, P.C.3
  • 7
    • 33746526525 scopus 로고    scopus 로고
    • Changes in NMDA receptor subunits and interacting PSD proteins in dorsolateral prefrontal and anterior cingulate cortex indicate abnormal regional expression in schizophrenia
    • Kristiansen LV, Beneyto M, Haroutunian V, et al. Changes in NMDA receptor subunits and interacting PSD proteins in dorsolateral prefrontal and anterior cingulate cortex indicate abnormal regional expression in schizophrenia. Mol Psychiatry 2006;11:737-47.
    • (2006) Mol Psychiatry , vol.11 , pp. 737-747
    • Kristiansen, L.V.1    Beneyto, M.2    Haroutunian, V.3
  • 8
    • 3042782805 scopus 로고    scopus 로고
    • Density of glutamic acid decarboxylase 67 messenger RNA-containing neurons that express the N-methyl-D-aspartate receptor subunit NR2A in the anterior cingulate cortex in schizophrenia and bipolar disorder
    • Woo T-U, Walsh JP, Benes FM. Density of glutamic acid decarboxylase 67 messenger RNA-containing neurons that express the N-methyl-D-aspartate receptor subunit NR2A in the anterior cingulate cortex in schizophrenia and bipolar disorder. Arch Gen Psychiatry 2004;61:649-57.
    • (2004) Arch Gen Psychiatry , vol.61 , pp. 649-657
    • Woo, T.-U.1    Walsh, J.P.2    Benes, F.M.3
  • 9
    • 84862810273 scopus 로고    scopus 로고
    • Gene expression of GABA and glutamate pathway markers in the prefrontal cortex of non-suicidal elderly depressed patients
    • Zhao J, Bao A-M, Qi X-R, et al. Gene expression of GABA and glutamate pathway markers in the prefrontal cortex of non-suicidal elderly depressed patients. J Affect Disord 2012;138:494-502.
    • (2012) J Affect Disord , vol.138 , pp. 494-502
    • Zhao, J.1    Bao, A.-M.2    Qi, X.-R.3
  • 10
    • 79954614494 scopus 로고    scopus 로고
    • Metabotropic glutamate receptors: From the workbench to the bedside
    • Nicoletti F, Bockaert J, Collingridge GL, et al. Metabotropic glutamate receptors: from the workbench to the bedside. Neuropharmacology 2011;60:1017-41.
    • (2011) Neuropharmacology , vol.60 , pp. 1017-1041
    • Nicoletti, F.1    Bockaert, J.2    Collingridge, G.L.3
  • 11
    • 84872735105 scopus 로고    scopus 로고
    • Metabotropic glutamate receptor 5 in the pathology and treatment of schizophrenia
    • Matosin N, Newell KA. Metabotropic glutamate receptor 5 in the pathology and treatment of schizophrenia. Neurosci Biobehav Rev 2013;37:256-68.
    • (2013) Neurosci Biobehav Rev , vol.37 , pp. 256-268
    • Matosin, N.1    Newell, K.A.2
  • 13
    • 84856072333 scopus 로고    scopus 로고
    • Metabotropic glutamate receptors as therapeutic targets for schizophrenia
    • Vinson PN, Conn JP. Metabotropic glutamate receptors as therapeutic targets for schizophrenia. Neuropharmacology 2012;62:1461-72.
    • (2012) Neuropharmacology , vol.62 , pp. 1461-1472
    • Vinson, P.N.1    Conn, J.P.2
  • 14
    • 84857921675 scopus 로고    scopus 로고
    • Reduced metabotropic glutamate receptor 5 in the Flinders Sensitive Line of rats, an animal model of depression: An autoradiographic study
    • Kovacevic T, Skelin I, Minuzzi L, et al. Reduced metabotropic glutamate receptor 5 in the Flinders Sensitive Line of rats, an animal model of depression: an autoradiographic study. Brain Res Bull 2012;87:406-12.
    • (2012) Brain Res Bull , vol.87 , pp. 406-412
    • Kovacevic, T.1    Skelin, I.2    Minuzzi, L.3
  • 15
    • 0035695488 scopus 로고    scopus 로고
    • Changes in the expression of metabotropic glutamate receptor 5 (mGluR5) in the rat hippocampus in an animal model of depression
    • Wieronska JM, Branski P, Szewczyk B, et al. Changes in the expression of metabotropic glutamate receptor 5 (mGluR5) in the rat hippocampus in an animal model of depression. Pol J Pharmacol 2001;53:659-62.
    • (2001) Pol J Pharmacol , vol.53 , pp. 659-662
    • Wieronska, J.M.1    Branski, P.2    Szewczyk, B.3
  • 16
    • 0034601620 scopus 로고    scopus 로고
    • The Stanley Foundation brain collection and Neuropathology Consortium
    • Torrey EF, Webster M, Knable M, et al. The Stanley Foundation brain collection and Neuropathology Consortium. Schizophr Res 2000;44:151-5.
    • (2000) Schizophr Res , vol.44 , pp. 151-155
    • Torrey, E.F.1    Webster, M.2    Knable, M.3
  • 17
    • 84858062262 scopus 로고    scopus 로고
    • Identification of proteomic signatures associated with depression and psychotic depression in post-mortem brains from major depression patients
    • Martins-de-Souza D, Guest PC, Harris LW, et al. Identification of proteomic signatures associated with depression and psychotic depression in post-mortem brains from major depression patients. Transl Psychiatry 2012;2:e87.
    • (2012) Transl Psychiatry , vol.2
    • Martins-De-Souza, D.1    Guest, P.C.2    Harris, L.W.3
  • 18
    • 18444373887 scopus 로고    scopus 로고
    • Distribution and abundance of metabotropic glutamate receptor subtype 2 in rat brain revealed by [3H]LY354740 binding in vitro and quantitative radioautography: Correlation with the sites of synthesis, expression, and agonist stimulation of [35S]GTPγs binding
    • Richards G, Messer J, Malherbe P, et al. Distribution and abundance of metabotropic glutamate receptor subtype 2 in rat brain revealed by [3H]LY354740 binding in vitro and quantitative radioautography: correlation with the sites of synthesis, expression, and agonist stimulation of [35S]GTPγs binding. J Comp Neurol 2005;487:15-27.
    • (2005) J Comp Neurol , vol.487 , pp. 15-27
    • Richards, G.1    Messer, J.2    Malherbe, P.3
  • 19
    • 79955485335 scopus 로고    scopus 로고
    • Density of metabotropic glutamate receptors 2 and 3 (mGluR2/3) in the dorsolateral prefrontal cortex does not differ with schizophrenia diagnosis but decreases with age
    • Frank E, Newell KA, Huang XF. Density of metabotropic glutamate receptors 2 and 3 (mGluR2/3) in the dorsolateral prefrontal cortex does not differ with schizophrenia diagnosis but decreases with age. Schizophr Res 2011;128:56-60.
    • (2011) Schizophr Res , vol.128 , pp. 56-60
    • Frank, E.1    Newell, K.A.2    Huang, X.F.3
  • 20
    • 43849110886 scopus 로고    scopus 로고
    • mGluR5 metabotropic glutamate receptors and dyskinesias in MPTP monkeys
    • Samadi P, Grégoire L, Morissette M, et al. mGluR5 metabotropic glutamate receptors and dyskinesias in MPTP monkeys. Neurobiol Aging 2008;29:1040-51.
    • (2008) Neurobiol Aging , vol.29 , pp. 1040-1051
    • Samadi, P.1    Grégoire, L.2    Morissette, M.3
  • 21
    • 84875942805 scopus 로고    scopus 로고
    • Metabotropic glutamate receptor 5 binding and protein expression in schizophrenia and following antipsychotic drug treatment
    • Matosin N, Frank E, Deng C, et al. Metabotropic glutamate receptor 5 binding and protein expression in schizophrenia and following antipsychotic drug treatment. Schizophr Res 2013;146:170-6.
    • (2013) Schizophr Res , vol.146 , pp. 170-176
    • Matosin, N.1    Frank, E.2    Deng, C.3
  • 22
    • 72449182114 scopus 로고    scopus 로고
    • The stanley neuropathology consortium integrative database: A novel, web-based tool for exploring neuropathological markers in psychiatric disorders and the biological processes associated with abnormalities of those markers
    • Kim S, Webster MJ. The stanley neuropathology consortium integrative database: a novel, web-based tool for exploring neuropathological markers in psychiatric disorders and the biological processes associated with abnormalities of those markers. Neuropsychopharmacology 2010;35:473-82.
    • (2010) Neuropsychopharmacology , vol.35 , pp. 473-482
    • Kim, S.1    Webster, M.J.2
  • 23
    • 84865532845 scopus 로고    scopus 로고
    • Neuropathology markers and pathways associated with molecular targets for antipsychotic drugs in postmortem brain tissues: Exploration of drug targets through the Stanley Neuropathology Integrative Database
    • Kim S, Zavitsanou K, Gurguis G, et al. Neuropathology markers and pathways associated with molecular targets for antipsychotic drugs in postmortem brain tissues: exploration of drug targets through the Stanley Neuropathology Integrative Database. Eur Neuropsychopharmacol 2012;22:683-94.
    • (2012) Eur Neuropsychopharmacol , vol.22 , pp. 683-694
    • Kim, S.1    Zavitsanou, K.2    Gurguis, G.3
  • 25
    • 79960539531 scopus 로고    scopus 로고
    • Reduced metabotropic glutamate receptor 5 density in major depression determined by [11C] ABP688 PET and postmortem study
    • Deschwanden A, Karolewicz B, Feyissa AM, et al. Reduced metabotropic glutamate receptor 5 density in major depression determined by [11C] ABP688 PET and postmortem study. Am J Psychiatry 2011;168:727-34.
    • (2011) Am J Psychiatry , vol.168 , pp. 727-734
    • Deschwanden, A.1    Karolewicz, B.2    Feyissa, A.M.3
  • 26
    • 79957492129 scopus 로고    scopus 로고
    • Altered expression of glutamate signaling, growth factor, and glia genes in the locus coeruleus of patients with major depression
    • Bernard R, Kerman IA, Thompson RC, et al. Altered expression of glutamate signaling, growth factor, and glia genes in the locus coeruleus of patients with major depression. Mol Psychiatry 2011;16:634-46.
    • (2011) Mol Psychiatry , vol.16 , pp. 634-646
    • Bernard, R.1    Kerman, I.A.2    Thompson, R.C.3
  • 27
    • 0036176446 scopus 로고    scopus 로고
    • Comparative analysis of group II metabotropic glutamate receptor immunoreactivity in Brodmann's area 46 of the dorsolateral prefrontal cortex from patients with schizophrenia and normal subjects
    • Crook JM, Akil M, Law BCW, et al. Comparative analysis of group II metabotropic glutamate receptor immunoreactivity in Brodmann's area 46 of the dorsolateral prefrontal cortex from patients with schizophrenia and normal subjects. Mol Psychiatry 2002;7:157-64.
    • (2002) Mol Psychiatry , vol.7 , pp. 157-164
    • Crook, J.M.1    Akil, M.2    Law, B.C.W.3
  • 28
    • 22544449233 scopus 로고    scopus 로고
    • Metabotropic glutamate receptor protein expression in the prefrontal cortex and striatum in schizophrenia
    • Gupta DS, McCullumsmith RE, Beneyto M, et al. Metabotropic glutamate receptor protein expression in the prefrontal cortex and striatum in schizophrenia. Synapse 2005;57:123-31.
    • (2005) Synapse , vol.57 , pp. 123-131
    • Gupta, D.S.1    McCullumsmith, R.E.2    Beneyto, M.3
  • 29
    • 0032078391 scopus 로고    scopus 로고
    • Expression of the human excitatory amino acid transporter 2 and metabotropic glutamate receptors 3 and 5 in the prefrontal cortex from normal individuals and patients with schizophrenia
    • Ohnuma T, Augood SJ, Arai H, et al. Expression of the human excitatory amino acid transporter 2 and metabotropic glutamate receptors 3 and 5 in the prefrontal cortex from normal individuals and patients with schizophrenia. Brain Res Mol Brain Res 1998;56:207-17.
    • (1998) Brain Res Mol Brain Res , vol.56 , pp. 207-217
    • Ohnuma, T.1    Augood, S.J.2    Arai, H.3
  • 30
    • 0034653205 scopus 로고    scopus 로고
    • Metabotropic glutamate receptor mRNA expression in the schizophrenic thalamus
    • Richardson-Burns SM, Haroutunian V, Davis KL, et al. Metabotropic glutamate receptor mRNA expression in the schizophrenic thalamus. Biol Psychiatry 2000;47:22-8.
    • (2000) Biol Psychiatry , vol.47 , pp. 22-28
    • Richardson-Burns, S.M.1    Haroutunian, V.2    Davis, K.L.3
  • 31
    • 78649743311 scopus 로고    scopus 로고
    • Alterations in metabotropic glutamate receptor 1a and regulator of G protein signaling 4 in the prefrontal cortex in schizophrenia
    • Volk DW, Eggan SM, Lewis DA. Alterations in metabotropic glutamate receptor 1a and regulator of G protein signaling 4 in the prefrontal cortex in schizophrenia. Am J Psychiatry 2010;167:1489-98.
    • (2010) Am J Psychiatry , vol.167 , pp. 1489-1498
    • Volk, D.W.1    Eggan, S.M.2    Lewis, D.A.3
  • 32
    • 84879977184 scopus 로고    scopus 로고
    • mRNA and protein expression for novel GABAA receptors θ and ρ2 are altered in schizophrenia and mood disorders; relevance to FMRP-mGluR5 signaling pathway
    • Fatemi SH, Folsom TD, Rooney RJ, et al. mRNA and protein expression for novel GABAA receptors θ and ρ2 are altered in schizophrenia and mood disorders; relevance to FMRP-mGluR5 signaling pathway. Transl Psychiatry 2013;3:e271.
    • (2013) Transl Psychiatry , vol.3
    • Fatemi, S.H.1    Folsom, T.D.2    Rooney, R.J.3
  • 33
    • 84892915525 scopus 로고    scopus 로고
    • Rethinking metabotropic glutamate receptor 5 pathological findings in psychiatric disorders: Implications for the future of novel therapeutics
    • Newell KA, Matosin N. Rethinking metabotropic glutamate receptor 5 pathological findings in psychiatric disorders: implications for the future of novel therapeutics. BMC Psychiatry 2014;14:23.
    • (2014) BMC Psychiatry , vol.14 , pp. 23
    • Newell, K.A.1    Matosin, N.2
  • 34
    • 0035878542 scopus 로고    scopus 로고
    • Modulation of glutamate receptors in response to the novel antipsychotic olanzapine in rats
    • Tascedda F, Blom JMC, Brunello N, et al. Modulation of glutamate receptors in response to the novel antipsychotic olanzapine in rats. Biol Psychiatry 2001;50:117-22.
    • (2001) Biol Psychiatry , vol.50 , pp. 117-122
    • Tascedda, F.1    Blom, J.M.C.2    Brunello, N.3
  • 35
    • 0036070326 scopus 로고    scopus 로고
    • Imipramine treatment up-regulates the expression and function of mGlu2/3 metabotropic glutamate receptors in the rat hippocampus
    • Matrisciano F, Storto M, Ngomba RT, et al. Imipramine treatment up-regulates the expression and function of mGlu2/3 metabotropic glutamate receptors in the rat hippocampus. Neuropharmacology 2002; 42:1008-15.
    • (2002) Neuropharmacology , vol.42 , pp. 1008-1015
    • Matrisciano, F.1    Storto, M.2    Ngomba, R.T.3
  • 36
    • 0036063314 scopus 로고    scopus 로고
    • Effect of chronic imipramine or electroconvulsive shock on the expression of mGluR1a and mGluR5a immunoreactivity in rat brain hippocampus
    • Smiałowska M, Szewczyk B, Branski P, et al. Effect of chronic imipramine or electroconvulsive shock on the expression of mGluR1a and mGluR5a immunoreactivity in rat brain hippocampus. Neuropharmacology 2002;42:1016-23.
    • (2002) Neuropharmacology , vol.42 , pp. 1016-1023
    • Smiałowska, M.1    Szewczyk, B.2    Branski, P.3
  • 37
    • 84884263412 scopus 로고    scopus 로고
    • Metabotropic glutamate receptor 5 in schizophrenia: Emerging evidence for the development of antipsychotic drugs
    • Newell KA. Metabotropic glutamate receptor 5 in schizophrenia: emerging evidence for the development of antipsychotic drugs. Future Med Chem 2013;5:1471-4.
    • (2013) Future Med Chem , vol.5 , pp. 1471-1474
    • Newell, K.A.1
  • 38
    • 84861460686 scopus 로고    scopus 로고
    • Pharmacogenetic analysis of the mGlu2/3 agonist LY2140023 monohydrate in the treatment of schizophrenia
    • Liu W, Downing ACM, Munsie LM, et al. Pharmacogenetic analysis of the mGlu2/3 agonist LY2140023 monohydrate in the treatment of schizophrenia. Pharmacogenomics J 2012;12:246-54.
    • (2012) Pharmacogenomics J , vol.12 , pp. 246-254
    • Liu, W.1    Downing, A.C.M.2    Munsie, L.M.3
  • 39
    • 84883472017 scopus 로고    scopus 로고
    • Treating older adults with schizophrenia: Challenges and opportunities
    • Jeste DV, Maglione JE. Treating older adults with schizophrenia: challenges and opportunities. Schizophr Bull 2013;39:966-8.
    • (2013) Schizophr Bull , vol.39 , pp. 966-968
    • Jeste, D.V.1    Maglione, J.E.2
  • 40
    • 0036850510 scopus 로고    scopus 로고
    • Selective alterations in ionotropic glutamate receptors in the anterior cingulate cortex in schizophrenia* 1
    • Zavitsanou K, Ward PB, Huang XF. Selective alterations in ionotropic glutamate receptors in the anterior cingulate cortex in schizophrenia* 1. Neuropsychopharmacology 2002;27:826-33.
    • (2002) Neuropsychopharmacology , vol.27 , pp. 826-833
    • Zavitsanou, K.1    Ward, P.B.2    Huang, X.F.3
  • 41
    • 34447098652 scopus 로고    scopus 로고
    • Expression of CB1 cannabinoid receptor in the anterior cingulate cortex in schizophrenia, bipolar disorder, and major depression
    • Koethe D, Llenos IC, Dulay JR, et al. Expression of CB1 cannabinoid receptor in the anterior cingulate cortex in schizophrenia, bipolar disorder, and major depression. J Neural Transm 2007;114:1055-63.
    • (2007) J Neural Transm , vol.114 , pp. 1055-1063
    • Koethe, D.1    Llenos, I.C.2    Dulay, J.R.3
  • 42
    • 38949102995 scopus 로고    scopus 로고
    • Low GABA concentrations in occipital cortex and anterior cingulate cortex in medication-free, recovered depressed patients
    • Bhagwagar Z, Wylezinska M, Jezzard P, et al. Low GABA concentrations in occipital cortex and anterior cingulate cortex in medication-free, recovered depressed patients. Int J Neuropsychopharmacol 2008;11:255-60.
    • (2008) Int J Neuropsychopharmacol , vol.11 , pp. 255-260
    • Bhagwagar, Z.1    Wylezinska, M.2    Jezzard, P.3
  • 43
    • 80054785554 scopus 로고    scopus 로고
    • Treatment of substance abusing patients with comorbid psychiatric disorders
    • Kelly TM, Daley DC, Douaihy AB. Treatment of substance abusing patients with comorbid psychiatric disorders. Addict Behav 2012;37:11-24.
    • (2012) Addict Behav , vol.37 , pp. 11-24
    • Kelly, T.M.1    Daley, D.C.2    Douaihy, A.B.3
  • 44
    • 12244296166 scopus 로고    scopus 로고
    • Substance misuse and psychiatric comorbidity: An overview of the OPCS National Psychiatric Morbidity Survey
    • Farrell M, Howes S, Taylor C, et al. Substance misuse and psychiatric comorbidity: an overview of the OPCS National Psychiatric Morbidity Survey. Int Rev Psychiatry 2003;15:43-9.
    • (2003) Int Rev Psychiatry , vol.15 , pp. 43-49
    • Farrell, M.1    Howes, S.2    Taylor, C.3
  • 45
    • 84878145810 scopus 로고    scopus 로고
    • mGluR1/5 receptor densities in the brains of alcoholic subjects: A whole-hemisphere autoradiography study
    • Kupila J, Kärkkäinen O, Laukkanen V, et al. mGluR1/5 receptor densities in the brains of alcoholic subjects: a whole-hemisphere autoradiography study. Psychiatry Res 2013;212:245-50.
    • (2013) Psychiatry Res , vol.212 , pp. 245-250
    • Kupila, J.1    Kärkkäinen, O.2    Laukkanen, V.3
  • 46
    • 84873691604 scopus 로고    scopus 로고
    • Rescue of infralimbic mGluR2 deficit restores control over drug-seeking behavior in alcohol dependence
    • Meinhardt MW, Hansson AC, Perreau-Lenz S, et al. Rescue of infralimbic mGluR2 deficit restores control over drug-seeking behavior in alcohol dependence. J Neurosci 2013;33:2794-806.
    • (2013) J Neurosci , vol.33 , pp. 2794-2806
    • Meinhardt, M.W.1    Hansson, A.C.2    Perreau-Lenz, S.3
  • 47
    • 70349782435 scopus 로고    scopus 로고
    • Metabotropic glutamate receptor ligands as potential therapeutics for addiction
    • Olive MF. Metabotropic glutamate receptor ligands as potential therapeutics for addiction. Curr Drug Abuse Rev 2009;2:83-98.
    • (2009) Curr Drug Abuse Rev , vol.2 , pp. 83-98
    • Olive, M.F.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.