Developing Pd(II) catalyzed double sp3 C-H alkoxylation for synthesis of symmetric and unsymmetric acetals

Organic Letters

Volumn 16, Issue 20, 2014, Pages 5278-5281

  Zong, Yu ^a   Rao, Yu ^a  

^a TSINGHUA UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 84908254800     PISSN: 15237060     EISSN: 15237052     Source Type: Journal    
DOI: 10.1021/ol502377x     Document Type: Article

References (55)

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55. The submission of the purified symmetrical acetals (Figure 2) to conditions described for the formation of unsymmetrical acetals only results in a small amount of unsymmetrical acetals (for more details, please see SI). This observation supports our proposed mechanism that the reaction does favor a sequential double C-H alkoxylation procedure, but not another pathway such as potential acetal exchange.