Stereoselective synthesis of β-alkylated α-amino acids via palladium-catalyzed alkylation of unactivated methylene C(sp3)-H Bonds with Primary Alkyl Halides

Journal of the American Chemical Society

Volumn 135, Issue 32, 2013, Pages 12135-12141

  Zhang, Shu Yu ^a   Li, Qiong ^a   He, Gang ^a   Nack, William A ^a   Chen, Gong ^a  

^a PENNSYLVANIA STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

C-H BOND; CARBOXAMIDES; CATALYTIC ALKYLATION; HALOACETATE; METHYL IODIDE; PALLADIUM-CATALYZED; PRIMARY ALKYL HALIDES; STEREOSELECTIVE SYNTHESIS;

ALKYLATION; CATALYSIS; ISOTOPES; SCAFFOLDS; STEREOCHEMISTRY; STEREOSELECTIVITY;

AMINO ACIDS;

ALPHA AMINO ACID; AMIDE; CARBENE; METHYL IODIDE; PALLADIUM;

ALKYLATION; ARTICLE; CHEMICAL STRUCTURE; COVALENT BOND; HYDROGEN BOND; STEREOCHEMISTRY; SYNTHESIS;

ACETATES; ALKYLATION; AMIDES; AMINO ACIDS; CATALYSIS; HALOGENS; HYDROCARBONS, IODINATED; PALLADIUM; STEREOISOMERISM;

EID: 84882270894     PISSN: 00027863     EISSN: 15205126     Source Type: Journal    
DOI: 10.1021/ja406484v     Document Type: Article

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