Suppression of the p66shc adapter protein by protocatechuic acid prevents the development of lung injury induced by intestinal ischemia reperfusion in mice

Journal of Trauma and Acute Care Surgery

Volumn 73, Issue 5, 2012, Pages 1130-1137

  Wang, Guang Zhi ^a   Yao, Ji Hong ^a   Jing, Hui Rong ^a   Zhang, Feng ^a   Lin, Mu Sen ^a   Shi, Lei ^a   Wu, Hang ^a   Gao, Dong Yan ^a   Liu, Ke Xin ^a   Tian, Xiao Feng ^a  

^a DALIAN MEDICAL UNIVERSITY   (China)

Author keywords

Intestinal I R; Lung injury; Mouse; p66shc; PCA

Indexed keywords

CASPASE 3; GLUTATHIONE; GLUTATHIONE PEROXIDASE; INTERLEUKIN 6; MANGANESE SUPEROXIDE DISMUTASE; MESSENGER RNA; P66SHC ADAPTOR PROTEIN; PROTEIN BCL XL; PROTEIN SHC; PROTOCATECHUIC ACID; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BLOOD SAMPLING; CONTROLLED STUDY; CYTOKINE PRODUCTION; DRUG EFFICACY; DRUG MEGADOSE; ENZYME ACTIVITY; ENZYME LINKED IMMUNOSORBENT ASSAY; HISTOPATHOLOGY; INTESTINE ISCHEMIA; LOW DRUG DOSE; LUNG INJURY; LUNG PARENCHYMA; MALE; MESENTERIC ARTERY; MESENTERIC ARTERY ISCHEMIA; MESENTERIC ISCHEMIA; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; RECEPTOR DOWN REGULATION; REPERFUSION INJURY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SUPERIOR MESENTERIC ANGIOGRAPHY; SURGICAL TECHNIQUE; TREATMENT DURATION; WESTERN BLOTTING;

ANIMALS; ANTICARCINOGENIC AGENTS; BCL-X PROTEIN; DISEASE MODELS, ANIMAL; HYDROXYBENZOATES; LUNG INJURY; MALE; MICE; MICE, INBRED ICR; REPERFUSION INJURY; RNA, MESSENGER; SHC SIGNALING ADAPTOR PROTEINS; SUPEROXIDE DISMUTASE;

EID: 84869763251     PISSN: 21630755     EISSN: 21630763     Source Type: Journal    
DOI: 10.1097/TA.0b013e318265d069     Document Type: Article

References (35)

1. Kalia N, Brown NJ, Wood R, Hopkinson K, Fairburn B, Pockley AG. Effects of intestinal ischemia-reperfusion injury on rat peripheral blood neutrophil activation. Dig Dis Sci. 2003;48: 1677-1684.
2. Pierro A, Eaton S. Intestinal ischemia reperfusion injury and multisystem organ failure. Semin Pediatr Surg. 2004;13: 11-17.
3. Hassoun HT, Kone BC, Mercer DW, Moody FG, Weisbrodt NW, Moore FA. Post-injury multiple organ failure: the role of the gut. Shock. 2001;15: 1-10.
4. Li C, Jackson RM. Reactive species mechanisms of cellular hypoxiareoxygenation injury. Am J Physiol Cell Physiol. 2002;282:C227YC241.
5. Guven A, Tunc T, Topal T, Kul M, Korkmaz A, Gundogdu G, Onguru O, Ozturk H. Alpha-lipoic acid and ebselen prevent ischemia/reperfusion injury in the rat intestine. Surg Today. 2008;38: 1029-1035.
6. Horie Y, Wolf R, Miyasaka M, Anderson DC, Granger DN. Leukocyte adhesion and hepatic microvascular responses to intestinal ischemia/reperfusion in rats. Gastroenterology. 1996;111: 666-673.
7. Schmeling DJ, Caty MG, Oldham KT, Guice KS, Hinshaw DB. Evidence for neutrophil-related acute lung injury after intestinal ischemia-reperfusion. Surgery. 1989;106: 195-201.
8. Ben DF, Yu XY, Ji GY, Zheng DY, Lv KY, Ma B, Xia ZF. TLR4 mediates lung injury and inflammation in intestinal ischemia-reperfusion. J Surg Res. 2012;174: 326-333.
9. Cerwinka WH, Cooper D, Krieglstein CF, Ross CR, McCord JM, Granger DN. Superoxide mediates endotoxin-induced platelet-endothelial cell adhesion in intestinal venules. Am J Physiol Heart Circ Physiol. 2003;284:H535YH541.
10. Farmer DG, Ke B, Shen XD, Kaldas FM, Gao F, Watson MJ, Busuttil RW, Kupiec-Weglinski JW. Interleukin-13 protects mouse intestine from ischemia and reperfusion injury through regulation of innate and adaptive immunity. Transplantation. 2011;91: 737-743.
11. Haga S, Terui K, Fukai M, Oikawa Y, Irani K, Furukawa H, Todo S, Ozaki M. Preventing hypoxia/reoxygenation damage to hepatocytes by p66shc ablation: up-regulation of antioxidant and antiapoptotic proteins. J Hepatol. 2008;48: 422-432.
12. Migliaccio E, Giorgio M, Mele S, Pelicci G, Reboldi P, Pandolfi PP, Lanfrancone L, Pelicci PG. The p66shc adaptor protein controls oxidative stress response and life span in mammals. Nature. 1999;402: 309-313.
13. Pellegrini M, Pacini S, Baldari CT. p66SHC: the apoptotic side of Shc proteins. Apoptosis. 2005;10: 13-18.
14. Francia P, Cosentino F, Schiavoni M, Huang Y, Perna E, Camici GG, Lüscher TF, Volpe M. p66 Shc protein, oxidative stress, and cardiovascular complications of diabetes: the missing link. J Mol Med. 2009;87: 885-891.
15. Purdom S, Chen QM. p66Shc: at the crossroad of oxidative stress and the genetics of aging. Trends Mol Med. 2003;9: 206-210.
16. Carpi A, Menabò R, Kaludercic N, Pelicci PG, Di Lisa F, Giorgio M. The cardioprotective effects elicited by p66Shc ablation demonstrate the crucial role of mitochondrial ROS formation in ischemia/reperfusion injury. Biochimica Biophys Acta. 2009;1787: 774-780.
17. Zaccagnini G, Martelli F, Magenta A, Cencioni C, Fasanaro P, Nicoletti C, Biglioli P, Pelicci PG, Capogrossi MC. p66ShcA and oxidative stress modulate myogenic differentiation and skeletal muscle regeneration after hind limb ischemia. J Biol Chem. 2007;282: 31453-31459.
18. Chan K, Chui SH,Wong D, Ha WY, Chan CL,Wong R. Protective effects of Danshensu from the aqueous extract of Salvia miltiorrhiza (Danshen) against homocysteine-induced endothelial dysfunction. Life Sci. 2004;75: 3157-3171.
19. Tseng TH, Hsu JD, Lo MH, Chu CY, Chou FP, Huang CL, Wang CJ. Inhibitory effect of Hibiscus protocatechuic acid on tumor promotion in mouse skin. Cancer Lett. 1998;126: 199-207.
20. Liu YM, Jiang B, Bao YM, An LJ. Protocatechuic acid inhibits apoptosis by mitochondrial dysfunction in rotenone-induced PC12 cells. Toxicol In Vitro. 2008;22: 430-437.
21. Giovannini C, Scazzocchio B, Matarrese P, Varì R, D'Archivio M, Di Benedetto R, Casciani S, Dessì MR, Straface E, Malorni W, et al. Apoptosis induced by oxidized lipids is associated with up-regulation of p66Shc in intestinal Caco-2 cells: protective effects of phenolic compounds. J Nutr Biochem. 2008;19: 118-128.
22. Lane JS, Todd KE, Lewis MP, Gloor B, Ashley SW, Reber HA, McFadden DW, Chandler CF. Interleukin-10 reduces the systemic inflammatory response in a murine model of intestinal ischemia/reperfusion. Surgery. 1997;122: 288-294.
23. Krajka-Ku̧niak V, Szaefer H, Baer-Dubowska W. Hepatic and extrahepatic expression of glutathione S-transferase isozymes in mice and its modulation by naturally occurring phenolic acids. Environ Toxicol Pharmacol. 2008;25: 27-32.
24. Nakamura Y, Torikai K, Ohigashi H. Toxic dose of a simple phenolic antioxidant, protocatechuic acid, attenuates the glutathione level in ICR mouse liver and kidney. J Agric Food Chem. 2001;49: 5674-5678.
25. Chiu CJ, McArdle AH, Brown R, Scott HJ, Gurd FN. Intestinal mucosal lesion in low-flow states: I. A morphological, hemodynamic, and metabolic reappraisal. Arch Surg. 1970;101: 478-483.
26. Mikawa K, Nishina K, Takao Y, Obara H. ONO-1714, a nitric oxide synthase inhibitor, attenuates endotoxin-induced acute lung injury in rabbits. Anesth Analg. 2003;97: 1751-1755.
27. Zhao HD, Zhang F, Shen G, Li YB, Li YH, Jing HR, Ma LF, Yao JH, Tian XF. Sulforaphane protects liver injury induced by intestinal ischemia reperfusion through Nrf2-ARE pathway. World J Gastroenterol. 2010;16: 3002-3010.
28. Zhou Y, Wang Q, Evers BM, Chung DH. Signal transduction pathways involved in oxidative stress-induced intestinal epithelial cell apoptosis. Pediatr Res. 2005;58: 1192-1197.
29. An S, Hishikawa Y, Liu J, Koji T. Lung injury after ischemia-reperfusion of small intestine in rats involves apoptosis of type II alveolar epithelial cells mediated by TNF-alpha and activation of Bid pathway. Apoptosis. 2007;12: 1989-2001.
30. Clark JS, Faisal A, Baliga R, Nagamine Y, Arany I. Cisplatin induces apoptosis through the ERK-p66shc pathway in renal proximal tubule cells. Cancer Lett. 2010;297: 165-170.
31. Menini S, Iacobini C, Ricci C, Oddi G, Pesce C, Pugliese F, Block K, Abboud HE, Giorgio M, Migliaccio E, et al. Ablation of the gene encoding p66 Shc protects mice against AGE-induced glomerulopathy by preventing oxidant-dependent tissue injury and further AGE accumulation. Diabetologia. 2007;50: 1997-2007.
32. Li Y, Yao JH, Hu XW, Fan Z, Huang L, Jing HR, Liu KX, Tian XF. Inhibition of Rho kinase by fasudil hydrochloride attenuates lung injury induced by intestinal ischemia and reperfusion. Life Sci. 2011; 88: 104-109.
33. Kops GJ, Dansen TB, Polderman PE, Saarloos I, Wirtz KW, Coffer PJ, Huang TT, Bos JL, Medema RH, Burgering BM. Forkhead transcription factor FOXO3a protects quiescent cells from oxidative stress. Nature. 2002;419: 316-321.
34. Cai W, He JC, Zhu L, Chen X, Striker GE, Vlassara H. AGE-receptor-1 counteracts cellular oxidant stress induced by AGEs via negative regulation of p66shc-dependent FKHRL1 phosphorylation. Am J Physiol Cell Physiol. 2008;294:C145YC152.
35. Nemoto S, Finkel T. Redox regulation of forkhead proteins through a p66shc-dependent signaling pathway. Science. 2002;295: 2450-2452.