Anti-hyperglycemic activity of Caralluma umbellata haw

BioImpacts

Volumn 4, Issue 3, 2014, Pages 113-116

  Bellamakondi, Pavan Kumar ^a   Godavarthi, Ashok ^a   Ibrahim, Mohammed ^b  

^a Radiant Research Services Pvt Ltd   (India)

^b Nizam Institute of Pharmacy   (India)

Author keywords

Alpha amylase; Diabetes mellitus; Pancreatic lipase; PI3 kinase; Wortmannin

Indexed keywords

AMYLASE; ANTIDIABETIC AGENT; CARALLUMA UMBELLATA EXTRACT; GLUCOSE; PLANT EXTRACT; TRIACYLGLYCEROL LIPASE; UNCLASSIFIED DRUG;

ANTIDIABETIC ACTIVITY; ARTICLE; CARALLUMA UMBELLATA; CONTROLLED STUDY; CYTOTOXICITY TEST; DRUG MECHANISM; DRUG SCREENING; ENZYME INHIBITION; GLUCOSE TRANSPORT; IN VITRO STUDY; MEDICINAL PLANT; MYOTUBE;

CARALLUMA UMBELLATA;

EID: 84908211789     PISSN: 22285652     EISSN: 22285660     Source Type: Journal    
DOI: 10.15171/bi.2014.003     Document Type: Article

References (25)

1. Rother KI. Diabetes treatment bridging the divide. N Engl J Med 2007; 356: 1499-501.
2. Clements RS Jr, Bell DS. Complications of diabetes: prevalence, detection, current treatment, and prognosis. Am J Med 1985; 79: 2-7.
3. Habibuddin M, Daghriri HA, Humaira T, Qahtani M, Hefzi A. Antidiabetic effect of alcoholic extract of Caralluma sinaica L. on streptozotocin-induced diabetic rabbits. J Ethnopharmacol 2008; 117: 215-20.
4. Latha S, Rajaram K, Suresh Kumar P. Hepatoprotective and antidiabetic effect of methanol extract of Caralluma fimbriata in streptatozocin induced diabetic albino rats. Int J Pharm Pharm Sci 2004; 6: 665-68.
5. Shanmugam G, Ayyavu M, Dowlathabad MR, Thangadurai D, Ganesan S. Hepatoprotective effect of Caralluma umbellata against acetaminophen induced oxidative stress and liver damage in rat. Journal of Pharmacy Research 2013;6:342-45.
6. de Sousa E, Zanatta IS, Pizzolatti MG, Szpoganicz B, Barreto Silva FRM. Hypoglycemic effect and antioxidant potential of Kaempferol-3, 7-O-(r)-di rhamnoside from Bauhinia forficata leaves. J Nat Prod 2004;6:829-32.
7. Hanamura T, Toshihiko H, Hirokazu K. Structural and functional characterization of polyphenols isolated from Acerola (Malpighia emarginata DC.) fruit. Biosci Biotechnol Biochem 2005; 69:280-6
8. Bellamakondi P, Godavarthi A, Ibrahim M, Kulkarni S, Naik RM, Maradam S. In vitro cytotoxicity of caralluma species by MTT and trypan blue dye exclusion. Asian J Pharm Clin Res 2014;7:17-19.
9. Kawanoa A, Nakamurab H, Hatab S, Minakawaa M, Miuraa Y, Yagasaki K. Hypoglycemic effect of aspalathin, a rooibos tea component from Aspalathus linearis, in type 2 diabetic model db/db mice. Phytomedicine 2009; 16:437-43
10. Oboh G, Ademiluyi AO, Faloye YM. Effect of combination on the antioxidant and inhibitory properties of tropical pepper varieties against α-amylase and α-glucosidase activities in vitro. J Med Food 2011;14:1152-58.
11. Bustanji Y, Issa A, Mohammad M, Hudaib M, Tawah K, Alkhatib H, et al. Inhibition of hormone sensitive lipase and pancreatic lipase by Rosmarinus officinalis extract and selected phenolic constituents. J Med Plants Res 2010; 4: 2235-42.
12. Ramesh M, Nageshwara RY, Rama KM, Rao A, Prabhakar MC, Madhava Reddy B. Antinociceptive and anti-inflammatory activity of carumbelloside-I isolated from Caralluma umbellata. J Ethnopharmacol 1999; 68:349-52.
13. Noipha K, Ratanachaiyavong S, Ninla-Aesong P. Enhancement of glucose transport by selected plant foods in muscle cell line L6. Diabetes Res Clin Pract 2010;89:e22-e26.
14. Jung KH, Ha E, Kim MJ, Uhm YK, Kim HK, Hong SJ, et al. Ganoderma lucidum extract stimulates glucose uptake in L6 rat skeletal muscle cells. Acta Biochim Pol 2006; 53: 597-601.
15. Khoddami A, Wilkes MA, Roberts TH. Techniques for Analysis of Plant Phenolic Compounds. Molecules 2013; 18: 2328-75.
16. Cheng Z, Pang T, Gu M, Gao AH, Xie CM, Li JY, et al. Berberine-stimulated glucose uptake in L6 myotubes involves both AMPK and p38 MAPK. Biochim Biophys Acta 2006; 1760:1682-9.
17. Wijesekara N, Thong FSL, Antonescu CN, Klip A. Diverse Signals Regulate Glucose Uptake into Skeletal Muscle. Can J Diabetes 2006; 30:80-8.
18. Rhabasa-Lhoret R, Chiasson JL. Alpha-glucosidase inhibitiors. 3rd edition. In: Defronzo RA, Ferrannini E, Keen H, Zimmet P, editors. International Textbook of Diabetes Mellitus. Chichester:John Wiley; 2004.
19. Bhandari MR, Nilubon JA, Hong G, Kawabata J. α-Glucosidase and α- amylase inhibitory activities of Nepalese medicinal herb Pakhanbhed (Bergeniaciliata, Haw.). Food Chem 2004; 106: 247-52.
20. Kim JS, Hyun TK, Kim MJ. The inhibitory effects of ethanol extracts from sorghum, foxtail millet and proso millet on α-glucosidase and α-amylase activities. Food Chem 2011; 124: 1647-51.
21. Birari RB, Bhutani KK. Pancreatic lipase inhibitors from natural sources: unexplored potential. Drug Discov Today 2007; 12:879-9.
22. Lowe ME. Pancreatic triglyceride lipase and colipase: insights into dietary fat digestion. Gastroenterology 1994; 107:1524-36.
23. Kim TH, Kim JK, Ito H, Jo C. Enhancement of pancreatic lipase inhibitory activity of curcumin by radiolytic transformation. Bioorg Med Chem Lett 2011; 21:1512-14.
24. Liu S, Li D, Huang B, Chen Y, Lu X, Wang Y. Inhibition of pancreatic lipase, α-glucosidase, α-amylase, and hypolipidemic effects of the total flavonoids from Nelumbo nucifera leaves. J Ethnopharmacol 2013; 149: 263-9.
25. Sugiyama H, Akazome Y, Shoji T, Yamaguchi A, Yasue M, Kanda T, et al. Oligomeric procyanidins in apple polyphenol are main active components for inhibition of pancreatic lipase and triglyceride absorption. J. Agric Food Chem 2007; 55:4604-09.