Novel microscale approaches for easy, rapid determination of protein stability in academic and commercial settings

Biochimica et Biophysica Acta - Proteins and Proteomics

Volumn 1844, Issue 12, 2014, Pages 2241-2250

  Alexander, Crispin G ^a   Wanner, Randy ^b,c   Johnson, Christopher M ^d   Breitsprecher, Dennis ^c   Winter, Gerhard ^b   Duhr, Stefan ^c   Baaske, Philipp ^c   Ferguson, Neil ^a  

^a UNIVERSITY COLLEGE DUBLIN   (Ireland)

^b UNIVERSITY OF MUNICH   (Germany)

^c NanoTemper Technologies GmbH   (Germany)

^d MRC LABORATORY OF MOLECULAR BIOLOGY   (United Kingdom)

Author keywords

Chemical denaturation; Ligand screening; Low protein consumption; Microscale thermophoresis; Thermal denaturation

Indexed keywords

ARTICLE; AUTOMATION; BINDING AFFINITY; DENATURATION; FLUORESCENCE; PDZ DOMAIN; PROTEIN AGGREGATION; PROTEIN INTAKE; PROTEIN INTERACTION; PROTEIN PURIFICATION; PROTEIN STABILITY; TEMPERATURE; TEMPERATURE DEPENDENCE; THERMODYNAMICS; TITRIMETRY;

EID: 84908193839     PISSN: 15709639     EISSN: 18781454     Source Type: Journal    
DOI: 10.1016/j.bbapap.2014.09.016     Document Type: Article

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