Global structural motions from the strain of a single hydrogen bond

Proceedings of the National Academy of Sciences of the United States of America

Volumn 110, Issue 10, 2013, Pages 3829-3834

  Danielsson, Jens ^a   Awad, Wael ^b,c   Saraboji, Kadhirvel ^b   Kurnik, Martin ^a   Lang, Lisa ^a   Leinartaite, Lina ^a   Marklund, Stefan L ^d   Logan, Derek T ^b   Oliveberg, Mikael ^a  

^a STOCKHOLM UNIVERSITY   (Sweden)

^b LUND UNIVERSITY   (Sweden)

^c CAIRO UNIVERSITY   (Egypt)

^d UMEÅ UNIVERSITY   (Sweden)

Author keywords

Allostery; Local unfolding; Metal binding; Protein aggregation; Structural frustration

Indexed keywords

CARBONYL DERIVATIVE; COPPER; COPPER ZINC SUPEROXIDE DISMUTASE;

AMYOTROPHIC LATERAL SCLEROSIS; ARTICLE; BETA SHEET; DEGENERATIVE DISEASE; ENZYME ACTIVE SITE; HYDROGEN BOND; HYDROPHOBICITY; METAL BINDING; MOLECULAR DYNAMICS; MOTION; NUCLEAR MAGNETIC RESONANCE; PRIORITY JOURNAL; PROTEIN FOLDING; PROTEIN LOCALIZATION; PROTEIN PROCESSING; PROTEIN STABILITY; X RAY CRYSTALLOGRAPHY;

AMINO ACID SUBSTITUTION; AMYOTROPHIC LATERAL SCLEROSIS; APOENZYMES; CATALYTIC DOMAIN; CRYSTALLOGRAPHY, X-RAY; DEUTERIUM EXCHANGE MEASUREMENT; EVOLUTION, MOLECULAR; HUMANS; HYDROGEN BONDING; MODELS, MOLECULAR; MOLECULAR DYNAMICS SIMULATION; MOTION; MUTAGENESIS, SITE-DIRECTED; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; PROTEIN FOLDING; PROTEIN MULTIMERIZATION; PROTEIN STRUCTURE, SECONDARY; RECOMBINANT PROTEINS; SUPEROXIDE DISMUTASE;

EID: 84874588889     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1217306110     Document Type: Article

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