Release of tensile strain on engineered human tendon tissue disturbs cell adhesions, changes matrix architecture, and induces an inflammatory phenotype

PLoS ONE

Volumn 9, Issue 1, 2014, Pages

  Bayer, Monika L ^a   Schjerling, Peter ^a   Herchenhan, Andreas ^a   Zeltz, Cedric ^b   Heinemeier, Katja M ^a   Christensen, Lise ^c   Krogsgaard, Michael ^c   Gullberg, Donald ^b   Kjaer, Michael ^a  

^a UNIVERSITY OF COPENHAGEN   (Denmark)

^b UNIVERSITY OF BERGEN   (Norway)

^c UNIVERSITY OF COPENHAGEN   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA11 INTEGRIN; ALPHA2 INTEGRIN; GLYCOPROTEIN; INTEGRIN RECEPTOR; MATRIX PROTEIN; MESSENGER RNA; TRANSFORMING GROWTH FACTOR BETA1; UNCLASSIFIED DRUG;

ARTICLE; CELL ADHESION; CELL DIFFERENTIATION; COMPARATIVE STUDY; CONTROLLED STUDY; CYTOARCHITECTURE; EXTRACELLULAR MATRIX; HUMAN; HUMAN CELL; IN VITRO STUDY; INFLAMMATION; MECHANICAL STIMULATION; MECHANICAL STRESS; MONOLAYER CULTURE; PROTEIN EXPRESSION; TENDON; TISSUE ENGINEERING;

ADOLESCENT; ADULT; BIOLOGICAL MARKERS; CELL ADHESION; CELLULAR MICROENVIRONMENT; COLLAGEN; EXTRACELLULAR MATRIX; GENE EXPRESSION REGULATION; HUMANS; INFLAMMATION; INFLAMMATION MEDIATORS; INTEGRINS; PHENOTYPE; PROTEIN SUBUNITS; RNA, MESSENGER; STRESS, MECHANICAL; TENDONS; TENSILE STRENGTH; TIME FACTORS; TISSUE CULTURE TECHNIQUES; TISSUE ENGINEERING; TISSUE SCAFFOLDS; TRANSFORMING GROWTH FACTOR BETA1; YOUNG ADULT;

EID: 84908179517     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0086078     Document Type: Article

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