Tolerogenic signaling by pulmonary CD1c+ dendritic cells induces regulatory T cells in patients with chronic obstructive pulmonary disease by IL-27/IL-10/inducible costimulator ligand

Journal of Allergy and Clinical Immunology

Volumn 134, Issue 4, 2014, Pages 944-954.e8

  Tsoumakidou, Maria ^a   Tousa, Sofia ^b   Semitekolou, Maria ^b   Panagiotou, Panagiota ^a   Panagiotou, Anna ^a   Morianos, Ioannis ^b   Litsiou, Eleni ^a   Trochoutsou, Aikaterini I ^b   Konstantinou, Maria ^c   Potaris, Konstantinos ^c   Footitt, Joseph ^d   Mallia, Patrick ^d   Zakynthinos, Spyros ^a   Johnston, Sebastian L ^d   Xanthou, Georgina ^b  

^a UNIVERSITY OF ATHENS MEDICAL SCHOOL   (Greece)

^b BIOMEDICAL RESEARCH FOUNDATION   (Greece)

^c SOTIRIA GENERAL HOSPITAL   (Greece)

^d NATIONAL HEART AND LUNG INSTITUTE   (United Kingdom)

Author keywords

Chronic obstructive pulmonary disease; dendritic cells; IL 10; IL 27; inducible costimulator ligand; regulatory T cells

Indexed keywords

CD1C ANTIGEN; CHEMOKINE RECEPTOR CCR7; CYTOTOXIC T LYMPHOCYTE ANTIGEN 4; GAMMA INTERFERON; HLA G ANTIGEN; INDUCIBLE T CELL COSTIMULATOR LIGAND; INTERLEUKIN 10; INTERLEUKIN 17; INTERLEUKIN 23; INTERLEUKIN 27; INTERLEUKIN 6; LIPOPOLYSACCHARIDE; ALLOANTIGEN; CD1 ANTIGEN; CD1C PROTEIN, HUMAN; GLYCOPROTEIN; INDUCIBLE T CELL COSTIMULATOR;

ADULT; ARTICLE; CELL PROLIFERATION; CELL SUSPENSION; CHRONIC OBSTRUCTIVE LUNG DISEASE; CONTROLLED STUDY; DENDRITIC CELL; DISEASE EXACERBATION; FEMALE; FLOW CYTOMETRY; HUMAN; HUMAN TISSUE; IMMUNE RESPONSE; IMMUNOSUPPRESSIVE TREATMENT; IMMUNOSURVEILLANCE; IN VITRO STUDY; IN VIVO STUDY; ISOLATED LUNG; LYMPHOCYTE DIFFERENTIATION; MAJOR CLINICAL STUDY; MALE; MIXED LYMPHOCYTE REACTION; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; REGULATORY T LYMPHOCYTE; RHINOVIRUS; RHINOVIRUS INFECTION; SCANNING ELECTRON MICROSCOPY; UPREGULATION; AGED; BYSTANDER EFFECT; CELL CULTURE; CELL DIFFERENTIATION; COMPLICATION; DISEASE COURSE; GENETICS; HELPER CELL; IMMUNOLOGICAL TOLERANCE; IMMUNOLOGY; LUNG; LYMPHOCYTE ACTIVATION; METABOLISM; MIDDLE AGED; MIXED LYMPHOCYTE CULTURE; SIGNAL TRANSDUCTION; VIROLOGY;

AGED; ANTIGENS, CD1; BYSTANDER EFFECT; CELL DIFFERENTIATION; CELLS, CULTURED; DENDRITIC CELLS; DISEASE PROGRESSION; FEMALE; GLYCOPROTEINS; HUMANS; IMMUNE TOLERANCE; INDUCIBLE T-CELL CO-STIMULATOR PROTEIN; INTERLEUKIN-10; INTERLEUKIN-27; ISOANTIGENS; LUNG; LYMPHOCYTE ACTIVATION; LYMPHOCYTE CULTURE TEST, MIXED; MALE; MIDDLE AGED; PULMONARY DISEASE, CHRONIC OBSTRUCTIVE; RHINOVIRUS; SIGNAL TRANSDUCTION; T-LYMPHOCYTES, HELPER-INDUCER; T-LYMPHOCYTES, REGULATORY;

EID: 84908145000     PISSN: 00916749     EISSN: 10976825     Source Type: Journal    
DOI: 10.1016/j.jaci.2014.05.045     Document Type: Article

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