Diapocynin, a dimer of the NADPH oxidase inhibitor apocynin, reduces ROS production and prevents force loss in eccentrically contracting dystrophic muscle

PLoS ONE

Volumn 9, Issue 10, 2014, Pages

  Ismail, Hesham M ^a   Scapozza, Leonardo ^a   Ruegg, Urs T ^a   Dorchies, Olivier M ^a  

^a UNIVERSITY OF GENEVA   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

APOCYNIN; CALCIUM INDEPENDENT PHOSPHOLIPASE A2; CALCIUM ION; DIAPOCYNIN; DIMER; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; UNCLASSIFIED DRUG; ACETOPHENONE DERIVATIVE; ANTIOXIDANT; BIPHENYL DERIVATIVE; DYSTROPHIN; PHOSPHOLIPASE A2;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CALCIUM TRANSPORT; CONTROLLED STUDY; DRUG EFFICACY; ECCENTRIC MUSCLE CONTRACTION; IN VITRO STUDY; MEMBRANE DAMAGE; MOUSE; MUSCULAR DYSTROPHY; MYOTUBE; NONHUMAN; PROTEIN SYNTHESIS INHIBITION; WILD TYPE; ANIMAL; ANTAGONISTS AND INHIBITORS; BIOSYNTHESIS; CALCIUM SIGNALING; DEFICIENCY; DRUG EFFECTS; GENETICS; METABOLISM; MUSCLE CONTRACTION; MUSCULAR DYSTROPHY, DUCHENNE; PATHOLOGY; SKELETAL MUSCLE; X CHROMOSOME LINKED MUSCULAR DYSTROPHIC MOUSE;

ACETOPHENONES; ANIMALS; ANTIOXIDANTS; BIPHENYL COMPOUNDS; CALCIUM SIGNALING; DYSTROPHIN; MICE; MICE, INBRED MDX; MUSCLE CONTRACTION; MUSCLE, SKELETAL; MUSCULAR DYSTROPHY, DUCHENNE; NADPH OXIDASE; PHOSPHOLIPASES A2; REACTIVE OXYGEN SPECIES;

EID: 84908128403     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0110708     Document Type: Article

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