The reactivity of ortho-methoxy-substituted catechol radicals with sulfhydryl groups: Contribution for the comprehension of the mechanism of inhibition of NADPH oxidase by apocynin

Biochemical Pharmacology

Volumn 74, Issue 3, 2007, Pages 457-464

  Kanegae, Marília P P ^a   da Fonseca, Luiz Marcos ^a   Brunetti, Iguatemy L ^a   de Oliveira Silva, Sueli ^b   Ximenes, Valdecir F ^a  

^a SÃO PAULO STATE UNIVERSITY UNESP   (Brazil)

^b STATE UNIVERSITY OF MARINGÁ   (Brazil)

Author keywords

Apocynin; Methoxy catechols; Myeloperoxidase; NADPH oxidase; Neutrophyl; Sulfhydryl residues

Indexed keywords

4 CYANOGUAIACOL; 4 ETHYLGUAIACOL; 4 NITROGUAIACOL; APOCYNIN; CATECHOL DERIVATIVE; CREOSOL; GLUTATHIONE; HYDROGEN PEROXIDE; HYDROXYL GROUP; METHOXYCATECHOL; OVALBUMIN; PEROXIDASE; RADICAL; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; THIOL GROUP; UNCLASSIFIED DRUG; VANILLIN;

ARTICLE; CONTROLLED STUDY; CORRELATION ANALYSIS; CYTOSOL; DRUG MECHANISM; ELECTRON; ENZYME INACTIVATION; ENZYME INHIBITION; HUMAN; HUMAN CELL; INHIBITION KINETICS; NEUTROPHIL; OXIDATION; PRIORITY JOURNAL; REDUCTION; STRUCTURE ACTIVITY RELATION;

ACETOPHENONES; CATECHOLS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; GLUTATHIONE; HUMANS; NADPH OXIDASE; NEUTROPHILS; OXYGEN; SULFHYDRYL COMPOUNDS;

EID: 34250720665     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bcp.2007.05.004     Document Type: Article

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