HIV-1 protein NEF inhibits activity of ATP-binding cassette transporter A1 by targeting endoplasmic reticulum chaperone calnexin

Journal of Biological Chemistry

Volumn 289, Issue 42, 2014, Pages 28870-28884

  Jennelle, Lucas ^a,e   Hunegnaw, Ruth ^a   Dubrovsky, Larisa ^a   Pushkarsky, Tatiana ^a   Fitzgerald, Michael L ^b   Sviridov, Dmitri ^c   Popratiloff, Anastas ^d   Brichacek, Beda ^a   Bukrinsky, Michael ^a,f  

^a GEORGE WASHINGTON UNIVERSITY SCHOOL OF MEDICINE AND HEALTH SCIENCES   (United States)

^b MASSACHUSETTS GENERAL HOSPITAL   (United States)

^c BAKER IDI HEART AND DIABETES INSTITUTE   (Australia)

^d George Washington Center for Microscopy and Image Analysis Office of VP for Research   (United States)

^e UNIVERSITY OF VIRGINIA   (United States)

^f GEORGE WASHINGTON UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ATP-BINDING CASSETTE TRANSPORTERS; ENDOPLASMIC RETICULUM CHAPERONE;

ABC TRANSPORTER A1; CALNEXIN; GLYCOPROTEIN GP 160; NEF PROTEIN; SHORT HAIRPIN RNA; SMALL INTERFERING RNA; ABCA1 PROTEIN, HUMAN; CHOLESTEROL; GP160 PROTEIN, HUMAN IMMUNODEFICIENCY VIRUS 1; NEF PROTEIN, HUMAN IMMUNODEFICIENCY VIRUS 1; PROTEIN BINDING;

ARTICLE; BINDING AFFINITY; CELL DIFFERENTIATION; CELLULAR DISTRIBUTION; CHOLESTEROL METABOLISM; CHOLESTEROL TRANSPORT; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; DOWN REGULATION; ENDOPLASMIC RETICULUM; GENE SILENCING; GENETIC TRANSFECTION; GLYCOSYLATION; HEK293 CELL LINE; HELA CELL LINE; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS 1; MOLECULAR DYNAMICS; NONHUMAN; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN FOLDING; PROTEIN FUNCTION; PROTEIN PROCESSING; PROTEIN PROTEIN INTERACTION; PROTEIN TRANSPORT; REGULATORY MECHANISM; UPREGULATION; VIRUS CELL INTERACTION; ATHEROSCLEROSIS; ELECTROSPRAY MASS SPECTROMETRY; METABOLISM; TANDEM MASS SPECTROMETRY;

ATHEROSCLEROSIS; ATP BINDING CASSETTE TRANSPORTER 1; CALNEXIN; CHOLESTEROL; ENDOPLASMIC RETICULUM; GLYCOSYLATION; HEK293 CELLS; HELA CELLS; HIV ENVELOPE PROTEIN GP160; HIV-1; HUMANS; NEF GENE PRODUCTS, HUMAN IMMUNODEFICIENCY VIRUS; PROTEIN BINDING; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; TANDEM MASS SPECTROMETRY;

EID: 84908110298     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M114.583591     Document Type: Article

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