Hepatic monoacylglycerol O-acyltransferase 1 as a promising therapeutic target for steatosis, obesity, and type 2 diabetes

Molecular Therapy Nucleic Acids

Volumn 3, Issue , 2014, Pages e154-

  Hayashi, Yasuhiro ^a   Suemitsu, Erina ^a   Kajimoto, Kazuaki ^a   Sato, Yusuke ^a   Akhter, Afsana ^a   Sakurai, Yu ^a   Hatakeyama, Hiroto ^a   Hyodo, Mamoru ^a   Kaji, Noritada ^b   Baba, Yoshinobu ^b,c   Harashima, Hideyoshi ^a  

^a HOKKAIDO UNIVERSITY   (Japan)

^b NAGOYA UNIVERSITY   (Japan)

^c NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY AIST   (Japan)

Author keywords

In vivo siRNA delivery; Liver; Microarray; Monoacylglycerol O acyltransferase 1 (Mogat1); Type 2 diabetes

Indexed keywords

ACYLTRANSFERASE; ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; CHOLESTEROL; FATTY ACID; GLUCOSE; HOE 33342; INSULIN; LIVER ENZYME; MONOACYLGLYCEROL O ACYLTRANSFERASE 1; NANOPARTICLE; RHODAMINE; SMALL INTERFERING RNA; TRIACYLGLYCEROL; UNCLASSIFIED DRUG;

ALANINE AMINOTRANSFERASE BLOOD LEVEL; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; CHOLESTEROL BLOOD LEVEL; COMPARATIVE STUDY; CONFOCAL LASER MICROSCOPY; CONTROLLED STUDY; DIET INDUCED OBESITY; DISEASE ASSOCIATION; DISEASE COURSE; DNA MICROARRAY; DOWN REGULATION; ENZYME ACTIVITY; ENZYME ANALYSIS; ENZYME LINKED IMMUNOSORBENT ASSAY; FATTY LIVER; GENE SILENCING; GENE TARGETING; GLUCOSE BLOOD LEVEL; HISTOPATHOLOGY; IN VIVO STUDY; INSULIN BLOOD LEVEL; LIPID ABSORPTION; LIPID METABOLISM; LIQUID SCINTILLATION COUNTING; MALE; METABOLIC PARAMETERS; MOUSE; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; NONVIRAL GENE DELIVERY SYSTEM; OBESITY; PRIORITY JOURNAL; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TISSUE DISTRIBUTION; TRANSCRIPTOMICS; UPREGULATION;

EID: 84908108811     PISSN: None     EISSN: 21622531     Source Type: Journal    
DOI: 10.1038/mtna.2014.4     Document Type: Article

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