Vasculotide, an Angiopoietin-1 mimetic, reduces acute skin ionizing radiation damage in a preclinical mouse model

BMC Cancer

Volumn 14, Issue 1, 2014, Pages

  Korpela, Elina ^a,b   Yohan, Darren ^c   Chin, Lee C L ^b,c,d   Kim, Anthony ^d   Huang, Xiaoyong ^a   Sade, Shachar ^a,b   Van Slyke, Paul ^a   Dumont, Daniel J ^a,b   Liu, Stanley K ^a,b  

^a SUNNYBROOK RESEARCH INSTITUTE   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

^c RYERSON UNIVERSITY   (Canada)

^d DEPARTMENT OF RADIATION ONCOLOGY   (Canada)

Author keywords

Acute radiation toxicity; Angiopoietin 1; Diffuse reflectance spectroscopy; Endothelial cells; Inflammation; Radiotherapy; Skin; Tie2; Vasculotide; Wound healing

Indexed keywords

CYTOKINE; HEMOGLOBIN; MYELOPEROXIDASE; RADIOPROTECTIVE AGENT; UNCLASSIFIED DRUG; VASCULOTIDE; ANGIOPOIETIN 1; BIOMIMETIC MATERIAL; PEPTIDE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BIOASSAY; BIOLUMINESCENCE; CAPILLARY ENDOTHELIAL CELL; CELL SURVIVAL; CONTROLLED STUDY; DIFFUSE REFLECTANCE SPECTROSCOPY; DRUG MECHANISM; DRUG RESPONSE; FEMALE; HISTOLOGY; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; IN VIVO STUDY; INFLAMMATION; IONIZING RADIATION; MOUSE; NEUTROPHIL; NONHUMAN; PROTEIN BLOOD LEVEL; RADIATION DOSE; RADIATION EXPOSURE; RADIATION INJURY; RADIATION PROTECTION; SKIN INJURY; SPECTROSCOPY; WOUND HEALING; XENOGRAFT; ANGIOGENESIS; ANIMAL; BLOOD; CELL LINE; CHEMISTRY; CYTOLOGY; DOSE RESPONSE; DRUG EFFECTS; ENDOTHELIUM CELL; HUMAN; NUDE MOUSE; PATHOLOGY; RADIATION INJURIES, EXPERIMENTAL; RADIATION RESPONSE; SKIN;

ANGIOPOIETIN-1; ANIMALS; BIOMIMETIC MATERIALS; CELL LINE; CELL SURVIVAL; CYTOKINES; DOSE-RESPONSE RELATIONSHIP, DRUG; DOSE-RESPONSE RELATIONSHIP, RADIATION; ENDOTHELIAL CELLS; HUMANS; MICE; MICE, NUDE; NEOVASCULARIZATION, PHYSIOLOGIC; PEPTIDES; RADIATION INJURIES, EXPERIMENTAL; RADIATION, IONIZING; SKIN; WOUND HEALING;

EID: 84908069395     PISSN: None     EISSN: 14712407     Source Type: Journal    
DOI: 10.1186/1471-2407-14-614     Document Type: Article

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