-
1
-
-
0029001244
-
Distinct roles of the receptor tyrosine kinases Tie-1 and Tie-2 in blood vessel formation
-
10.1038/376070a0, 7596437
-
Sato TN, Tozawa Y, Deutsch U, Wolburg-Buchholz K, Fujiwara Y, Gendron-Maguire M, Gridley T, Wolburg H, Risau W, Qin Y. Distinct roles of the receptor tyrosine kinases Tie-1 and Tie-2 in blood vessel formation. Nature 1995, 376:70-74. 10.1038/376070a0, 7596437.
-
(1995)
Nature
, vol.376
, pp. 70-74
-
-
Sato, T.N.1
Tozawa, Y.2
Deutsch, U.3
Wolburg-Buchholz, K.4
Fujiwara, Y.5
Gendron-Maguire, M.6
Gridley, T.7
Wolburg, H.8
Risau, W.9
Qin, Y.10
-
2
-
-
0030460424
-
Isolation of angiopoietin-1, a ligand for the TIE2 receptor, by secretion-trap expression cloning
-
10.1016/S0092-8674(00)81812-7, 8980223
-
Davis S, Aldrich TH, Jones PF, Acheson A, Compton DL, Jain V, Ryan TE, Bruno J, Radziejewski C, Maisonpierre PC, Yancopoulos GD. Isolation of angiopoietin-1, a ligand for the TIE2 receptor, by secretion-trap expression cloning. Cell 1996, 87:1161-1169. 10.1016/S0092-8674(00)81812-7, 8980223.
-
(1996)
Cell
, vol.87
, pp. 1161-1169
-
-
Davis, S.1
Aldrich, T.H.2
Jones, P.F.3
Acheson, A.4
Compton, D.L.5
Jain, V.6
Ryan, T.E.7
Bruno, J.8
Radziejewski, C.9
Maisonpierre, P.C.10
Yancopoulos, G.D.11
-
3
-
-
0030480322
-
Requisite role of angiopoietin-1, a ligand for the TIE2 receptor, during embryonic angiogenesis
-
10.1016/S0092-8674(00)81813-9, 8980224
-
Suri C, Jones PF, Patan S, Bartunkova S, Maisonpierre PC, Davis S, Sato TN, Yancopoulos GD. Requisite role of angiopoietin-1, a ligand for the TIE2 receptor, during embryonic angiogenesis. Cell 1996, 87:1171-1180. 10.1016/S0092-8674(00)81813-9, 8980224.
-
(1996)
Cell
, vol.87
, pp. 1171-1180
-
-
Suri, C.1
Jones, P.F.2
Patan, S.3
Bartunkova, S.4
Maisonpierre, P.C.5
Davis, S.6
Sato, T.N.7
Yancopoulos, G.D.8
-
4
-
-
0034036689
-
Angiopoietin-1 protects the adult vasculature against plasma leakage
-
10.1038/74725, 10742156
-
Thurston G, Rudge JS, Ioffe E, Zhou H, Ross L, Croll SD, Glazer N, Holash J, McDonald DM, Yancopoulos GD. Angiopoietin-1 protects the adult vasculature against plasma leakage. Nat Med 2000, 6:460-463. 10.1038/74725, 10742156.
-
(2000)
Nat Med
, vol.6
, pp. 460-463
-
-
Thurston, G.1
Rudge, J.S.2
Ioffe, E.3
Zhou, H.4
Ross, L.5
Croll, S.D.6
Glazer, N.7
Holash, J.8
McDonald, D.M.9
Yancopoulos, G.D.10
-
5
-
-
37549002096
-
Angiopoietin-1 increases survival and reduces the development of lung edema induced by endotoxin administration in a murine model of acute lung injury
-
10.1097/01.CCM.0000297955.02633.A4, 18007265
-
Huang YQ, Sauthoff H, Herscovici P, Pipiya T, Cheng J, Heitner S, Szentirmai O, Carter B, Hay JG. Angiopoietin-1 increases survival and reduces the development of lung edema induced by endotoxin administration in a murine model of acute lung injury. Crit Care Med 2008, 36:262-267. 10.1097/01.CCM.0000297955.02633.A4, 18007265.
-
(2008)
Crit Care Med
, vol.36
, pp. 262-267
-
-
Huang, Y.Q.1
Sauthoff, H.2
Herscovici, P.3
Pipiya, T.4
Cheng, J.5
Heitner, S.6
Szentirmai, O.7
Carter, B.8
Hay, J.G.9
-
6
-
-
79959546082
-
Acute administration of recombinant Angiopoietin-1 ameliorates multiple-organ dysfunction syndrome and improves survival in murine sepsis
-
10.1016/j.cyto.2011.04.005, 21531574
-
David S, Park JK, van Meurs M, Zijlstra JG, Koenecke C, Schrimpf C, Shushakova N, Gueler F, Haller H, Kümpers P. Acute administration of recombinant Angiopoietin-1 ameliorates multiple-organ dysfunction syndrome and improves survival in murine sepsis. Cytokine 2011, 55:251-259. 10.1016/j.cyto.2011.04.005, 21531574.
-
(2011)
Cytokine
, vol.55
, pp. 251-259
-
-
David, S.1
Park, J.K.2
van Meurs, M.3
Zijlstra, J.G.4
Koenecke, C.5
Schrimpf, C.6
Shushakova, N.7
Gueler, F.8
Haller, H.9
Kümpers, P.10
-
7
-
-
34248381322
-
Cell-based angiopoietin-1 gene therapy for acute lung injury
-
10.1164/rccm.200609-1370OC, 17322110
-
McCarter SD, Mei SH, Lai PF, Zhang QW, Parker CH, Suen RS, Hood RD, Zhao YD, Deng Y, Han RN, Dumont DJ, Stewart DJ. Cell-based angiopoietin-1 gene therapy for acute lung injury. Am J Respir Crit Care Med 2007, 175:1014-1026. 10.1164/rccm.200609-1370OC, 17322110.
-
(2007)
Am J Respir Crit Care Med
, vol.175
, pp. 1014-1026
-
-
McCarter, S.D.1
Mei, S.H.2
Lai, P.F.3
Zhang, Q.W.4
Parker, C.H.5
Suen, R.S.6
Hood, R.D.7
Zhao, Y.D.8
Deng, Y.9
Han, R.N.10
Dumont, D.J.11
Stewart, D.J.12
-
8
-
-
62649112414
-
COMP-Ang1 ameliorates leukocyte adhesion and reinforces endothelial tight junctions during endotoxemia
-
10.1016/j.bbrc.2009.02.096, 19245790
-
Hwang JA, Lee EH, Lee SD, Park JB, Jeon BH, Cho CH. COMP-Ang1 ameliorates leukocyte adhesion and reinforces endothelial tight junctions during endotoxemia. Biochem Biophys Res Commun 2009, 381:592-596. 10.1016/j.bbrc.2009.02.096, 19245790.
-
(2009)
Biochem Biophys Res Commun
, vol.381
, pp. 592-596
-
-
Hwang, J.A.1
Lee, E.H.2
Lee, S.D.3
Park, J.B.4
Jeon, B.H.5
Cho, C.H.6
-
9
-
-
72949100522
-
COMP-angiopoietin-1 decreases lipopolysaccharide-induced acute kidney injury
-
10.1038/ki.2009.387, 19812542
-
Kim DH, Jung YJ, Lee AS, Lee S, Kang KP, Lee TH, Lee SY, Jang KY, Moon WS, Choi KS, Yoon KH, Sung MJ, Park SK, Kim W. COMP-angiopoietin-1 decreases lipopolysaccharide-induced acute kidney injury. Kidney Int 2009, 76:1180-1191. 10.1038/ki.2009.387, 19812542.
-
(2009)
Kidney Int
, vol.76
, pp. 1180-1191
-
-
Kim, D.H.1
Jung, Y.J.2
Lee, A.S.3
Lee, S.4
Kang, K.P.5
Lee, T.H.6
Lee, S.Y.7
Jang, K.Y.8
Moon, W.S.9
Choi, K.S.10
Yoon, K.H.11
Sung, M.J.12
Park, S.K.13
Kim, W.14
-
10
-
-
34447627607
-
Angiopoietin-1 requires p190 RhoGAP to protect against vascular leakage in vivo
-
10.1074/jbc.M702169200, 17562701
-
Mammoto T, Parikh SM, Mammoto A, Gallagher D, Chan B, Mostoslavsky G, Ingber DE, Sukhatme VP. Angiopoietin-1 requires p190 RhoGAP to protect against vascular leakage in vivo. J Biol Chem 2007, 282:23910-23918. 10.1074/jbc.M702169200, 17562701.
-
(2007)
J Biol Chem
, vol.282
, pp. 23910-23918
-
-
Mammoto, T.1
Parikh, S.M.2
Mammoto, A.3
Gallagher, D.4
Chan, B.5
Mostoslavsky, G.6
Ingber, D.E.7
Sukhatme, V.P.8
-
11
-
-
11244337801
-
Protective role of angiopoietin-1 in endotoxic shock
-
10.1161/01.CIR.0000151287.08202.8E, 15611372
-
Witzenbichler B, Westermann D, Knueppel S, Schultheiss HP, Tschope C. Protective role of angiopoietin-1 in endotoxic shock. Circulation 2005, 111:97-105. 10.1161/01.CIR.0000151287.08202.8E, 15611372.
-
(2005)
Circulation
, vol.111
, pp. 97-105
-
-
Witzenbichler, B.1
Westermann, D.2
Knueppel, S.3
Schultheiss, H.P.4
Tschope, C.5
-
12
-
-
2542453735
-
The Tie-2 ligand angiopoietin-2 is stored in and rapidly released upon stimulation from endothelial cell Weibel-Palade bodies
-
10.1182/blood-2003-10-3685, 14976056
-
Fiedler U, Scharpfenecker M, Koidl S, Hegen A, Grunow V, Schmidt JM, Kriz W, Thurston G, Augustin HG. The Tie-2 ligand angiopoietin-2 is stored in and rapidly released upon stimulation from endothelial cell Weibel-Palade bodies. Blood 2004, 103:4150-4156. 10.1182/blood-2003-10-3685, 14976056.
-
(2004)
Blood
, vol.103
, pp. 4150-4156
-
-
Fiedler, U.1
Scharpfenecker, M.2
Koidl, S.3
Hegen, A.4
Grunow, V.5
Schmidt, J.M.6
Kriz, W.7
Thurston, G.8
Augustin, H.G.9
-
13
-
-
36248988406
-
Admission angiopoietin levels in children with septic shock
-
2754128, 18092380
-
Giuliano JS, Lahni PM, Harmon K, Wong HR, Doughty LA, Carcillo JA, Zingarelli B, Sukhatme VP, Parikh SM, Wheeler DS. Admission angiopoietin levels in children with septic shock. Shock 2007, 28:650-654. 2754128, 18092380.
-
(2007)
Shock
, vol.28
, pp. 650-654
-
-
Giuliano, J.S.1
Lahni, P.M.2
Harmon, K.3
Wong, H.R.4
Doughty, L.A.5
Carcillo, J.A.6
Zingarelli, B.7
Sukhatme, V.P.8
Parikh, S.M.9
Wheeler, D.S.10
-
14
-
-
57649116087
-
Excess circulating angiopoietin-2 is a strong predictor of mortality in critically ill medical patients
-
10.1186/cc7130, 2646310, 19025590
-
Kümpers P, Lukasz A, David S, Horn R, Hafer C, Faulhaber-Walter R, Fliser D, Haller H, Kielstein JT. Excess circulating angiopoietin-2 is a strong predictor of mortality in critically ill medical patients. Crit Care 2008, 12:R147. 10.1186/cc7130, 2646310, 19025590.
-
(2008)
Crit Care
, vol.12
-
-
Kümpers, P.1
Lukasz, A.2
David, S.3
Horn, R.4
Hafer, C.5
Faulhaber-Walter, R.6
Fliser, D.7
Haller, H.8
Kielstein, J.T.9
-
15
-
-
66249134941
-
Time course of angiopoietin-2 release during experimental human endotoxemia and sepsis
-
10.1186/cc7866, 2717419, 19416526
-
Kümpers P, van Meurs M, David S, Molema G, Bijzet J, Lukasz A, Biertz F, Haller H, Zijlstra JG. Time course of angiopoietin-2 release during experimental human endotoxemia and sepsis. Crit Care 2009, 13:R64. 10.1186/cc7866, 2717419, 19416526.
-
(2009)
Crit Care
, vol.13
-
-
Kümpers, P.1
van Meurs, M.2
David, S.3
Molema, G.4
Bijzet, J.5
Lukasz, A.6
Biertz, F.7
Haller, H.8
Zijlstra, J.G.9
-
16
-
-
77951207233
-
Angiopoietin-2 in patients requiring renal replacement therapy in the ICU: relation to acute kidney injury, multiple organ dysfunction syndrome and outcome
-
10.1007/s00134-009-1726-7, 19956923
-
Kümpers P, Hafer C, David S, Hecker H, Lukasz A, Fliser D, Haller H, Kielstein JT, Faulhaber-Walter R. Angiopoietin-2 in patients requiring renal replacement therapy in the ICU: relation to acute kidney injury, multiple organ dysfunction syndrome and outcome. Intensive Care Med 2010, 36:462-470. 10.1007/s00134-009-1726-7, 19956923.
-
(2010)
Intensive Care Med
, vol.36
, pp. 462-470
-
-
Kümpers, P.1
Hafer, C.2
David, S.3
Hecker, H.4
Lukasz, A.5
Fliser, D.6
Haller, H.7
Kielstein, J.T.8
Faulhaber-Walter, R.9
-
17
-
-
77952432851
-
The role of angiogenic factors in predicting clinical outcome in severe bacterial infection in Malawian children
-
10.1186/cc8323, 2911728, 20492647, Study Group
-
Mankhambo LA, Banda DL, , Jeffers G, White SA, Balmer P, Nkhoma S, Phiri H, Molyneux EM, Hart CA, Molyneux ME, Heyderman RS, Carrol ED. Study Group The role of angiogenic factors in predicting clinical outcome in severe bacterial infection in Malawian children. Crit Care 2010, 14:R91. 10.1186/cc8323, 2911728, 20492647, Study Group.
-
(2010)
Crit Care
, vol.14
-
-
Mankhambo, L.A.1
Banda, D.L.2
Jeffers, G.3
White, S.A.4
Balmer, P.5
Nkhoma, S.6
Phiri, H.7
Molyneux, E.M.8
Hart, C.A.9
Molyneux, M.E.10
Heyderman, R.S.11
Carrol, E.D.12
-
18
-
-
33845940689
-
Angiopoietin-2 is increased in severe sepsis: correlation with inflammatory mediators
-
10.1097/01.CCM.0000251640.77679.D7, 17110873
-
Orfanos SE, Kotanidou A, Glynos C, Athanasiou C, Tsigkos S, Dimopoulou I, Sotiropoulou C, Zakynthinos S, Armaganidis A, Papapetropoulos A, Roussos C. Angiopoietin-2 is increased in severe sepsis: correlation with inflammatory mediators. Crit Care Med 2007, 35:199-206. 10.1097/01.CCM.0000251640.77679.D7, 17110873.
-
(2007)
Crit Care Med
, vol.35
, pp. 199-206
-
-
Orfanos, S.E.1
Kotanidou, A.2
Glynos, C.3
Athanasiou, C.4
Tsigkos, S.5
Dimopoulou, I.6
Sotiropoulou, C.7
Zakynthinos, S.8
Armaganidis, A.9
Papapetropoulos, A.10
Roussos, C.11
-
19
-
-
53649099512
-
Angiopoietin-2, permeability oedema, occurrence and severity of ALI/ARDS in septic and non-septic critically ill patients
-
10.1136/thx.2007.087387, 18559364
-
van der Heijden M, Nieuw Amerongen GP, Koolwijk P, van Hinsbergh VW, Groeneveld AB. Angiopoietin-2, permeability oedema, occurrence and severity of ALI/ARDS in septic and non-septic critically ill patients. Thorax 2008, 63:903-909. 10.1136/thx.2007.087387, 18559364.
-
(2008)
Thorax
, vol.63
, pp. 903-909
-
-
van der Heijden, M.1
Nieuw Amerongen, G.P.2
Koolwijk, P.3
van Hinsbergh, V.W.4
Groeneveld, A.B.5
-
20
-
-
44449145867
-
Circulating angiopoietin 2 correlates with mortality in a surgical population with acute lung injury/adult respiratory distress syndrome
-
Gallagher DC, Parikh SM, Balonov K, Miller A, Gautam S, Talmor D, Sukhatme VP. Circulating angiopoietin 2 correlates with mortality in a surgical population with acute lung injury/adult respiratory distress syndrome. Shock 2008, 29:656-661.
-
(2008)
Shock
, vol.29
, pp. 656-661
-
-
Gallagher, D.C.1
Parikh, S.M.2
Balonov, K.3
Miller, A.4
Gautam, S.5
Talmor, D.6
Sukhatme, V.P.7
-
21
-
-
52949126714
-
Plasma angiopoietin-2 levels increase in children following cardiopulmonary bypass
-
10.1007/s00134-008-1174-9, 2574898, 18516587
-
Giuliano JS, Lahni PM, Bigham MT, Manning PB, Nelson DP, Wong HR, Wheeler DS. Plasma angiopoietin-2 levels increase in children following cardiopulmonary bypass. Intensive Care Med 2008, 34:1851-1857. 10.1007/s00134-008-1174-9, 2574898, 18516587.
-
(2008)
Intensive Care Med
, vol.34
, pp. 1851-1857
-
-
Giuliano, J.S.1
Lahni, P.M.2
Bigham, M.T.3
Manning, P.B.4
Nelson, D.P.5
Wong, H.R.6
Wheeler, D.S.7
-
22
-
-
64849117308
-
Elevated serum angiopoietin 2 levels are associated with increased mortality in sepsis
-
10.1097/SHK.0b013e318188bd06, 18791490
-
Siner JM, Bhandari V, Engle KM, Elias JA, Siegel MD. Elevated serum angiopoietin 2 levels are associated with increased mortality in sepsis. Shock 2009, 31:348-353. 10.1097/SHK.0b013e318188bd06, 18791490.
-
(2009)
Shock
, vol.31
, pp. 348-353
-
-
Siner, J.M.1
Bhandari, V.2
Engle, K.M.3
Elias, J.A.4
Siegel, M.D.5
-
23
-
-
33645355399
-
Excess circulating angiopoietin-2 may contribute to pulmonary vascular leak in sepsis in humans
-
10.1371/journal.pmed.0030046, 1334221, 16417407
-
Parikh SM, Mammoto T, Schultz A, Yuan HT, Christiani D, Karumanchi SA, Sukhatme VP. Excess circulating angiopoietin-2 may contribute to pulmonary vascular leak in sepsis in humans. PLoS Med 2006, 3:e46. 10.1371/journal.pmed.0030046, 1334221, 16417407.
-
(2006)
PLoS Med
, vol.3
-
-
Parikh, S.M.1
Mammoto, T.2
Schultz, A.3
Yuan, H.T.4
Christiani, D.5
Karumanchi, S.A.6
Sukhatme, V.P.7
-
24
-
-
22944432543
-
Angiopoietin-2 causes inflammation in vivo by promoting vascular leakage
-
10.1124/jpet.105.086553, 15870388
-
Roviezzo F, Tsigkos S, Kotanidou A, Bucci M, Brancaleone V, Cirino G, Papapetropoulos A. Angiopoietin-2 causes inflammation in vivo by promoting vascular leakage. J Pharmacol Exp Ther 2005, 314:738-744. 10.1124/jpet.105.086553, 15870388.
-
(2005)
J Pharmacol Exp Ther
, vol.314
, pp. 738-744
-
-
Roviezzo, F.1
Tsigkos, S.2
Kotanidou, A.3
Bucci, M.4
Brancaleone, V.5
Cirino, G.6
Papapetropoulos, A.7
-
25
-
-
10944262091
-
A short synthetic peptide inhibits signal transduction, migration and angiogenesis mediated by Tie2 receptor
-
10.1038/sj.embor.7400100, 1299011, 14978510
-
Tournaire R, Simon MP, le NF, Eichmann A, England P, Pouyssegur J. A short synthetic peptide inhibits signal transduction, migration and angiogenesis mediated by Tie2 receptor. EMBO Rep 2004, 5:262-267. 10.1038/sj.embor.7400100, 1299011, 14978510.
-
(2004)
EMBO Rep
, vol.5
, pp. 262-267
-
-
Tournaire, R.1
Simon, M.P.2
le, N.F.3
Eichmann, A.4
England, P.5
Pouyssegur, J.6
-
26
-
-
66249112824
-
Acceleration of diabetic wound healing by an angiopoietin peptide mimetic
-
10.1089/ten.tea.2007.0400, 18939935
-
van Slyke P, Alami J, Martin D, Kuliszewski M, Leong-Poi H, Sefton MV, Dumont D. Acceleration of diabetic wound healing by an angiopoietin peptide mimetic. Tissue Eng Part A 2009, 15:1269-1280. 10.1089/ten.tea.2007.0400, 18939935.
-
(2009)
Tissue Eng Part A
, vol.15
, pp. 1269-1280
-
-
van Slyke, P.1
Alami, J.2
Martin, D.3
Kuliszewski, M.4
Leong-Poi, H.5
Sefton, M.V.6
Dumont, D.7
-
27
-
-
70349682279
-
Chemokine CXCL1/KC and its receptor CXCR2 are responsible for neutrophil chemotaxis in adenoviral keratitis
-
10.1089/jir.2009.0006, 2956677, 19642907
-
Chintakuntlawar AV, Chodosh J. Chemokine CXCL1/KC and its receptor CXCR2 are responsible for neutrophil chemotaxis in adenoviral keratitis. J Interferon Cytokine Res 2009, 29:657-666. 10.1089/jir.2009.0006, 2956677, 19642907.
-
(2009)
J Interferon Cytokine Res
, vol.29
, pp. 657-666
-
-
Chintakuntlawar, A.V.1
Chodosh, J.2
-
28
-
-
33749414768
-
Activation of Tie2 by angiopoietin-1 and angiopoietin-2 results in their release and receptor internalization
-
10.1242/jcs.03077, 16895971
-
Bogdanovic E, Nguyen VP, Dumont DJ. Activation of Tie2 by angiopoietin-1 and angiopoietin-2 results in their release and receptor internalization. J Cell Sci 2006, 119:3551-3560. 10.1242/jcs.03077, 16895971.
-
(2006)
J Cell Sci
, vol.119
, pp. 3551-3560
-
-
Bogdanovic, E.1
Nguyen, V.P.2
Dumont, D.J.3
-
29
-
-
0037588986
-
The role of the endothelium in severe sepsis and multiple organ dysfunction syndrome
-
10.1182/blood-2002-06-1887, 12543869
-
Aird WC. The role of the endothelium in severe sepsis and multiple organ dysfunction syndrome. Blood 2003, 101:3765-3777. 10.1182/blood-2002-06-1887, 12543869.
-
(2003)
Blood
, vol.101
, pp. 3765-3777
-
-
Aird, W.C.1
-
30
-
-
27144483559
-
Microvascular dysfunction as a cause of organ dysfunction in severe sepsis
-
10.1186/cc3748, 16168075
-
Vincent JL, De Backer D. Microvascular dysfunction as a cause of organ dysfunction in severe sepsis. Crit Care 2005, 9(Suppl 4):S9-12. 10.1186/cc3748, 16168075.
-
(2005)
Crit Care
, vol.9
, Issue.SUPPL. 4
-
-
Vincent, J.L.1
De Backer, D.2
-
31
-
-
75749145866
-
Angiopoietin-1/Tie2 signaling pathway inhibits lipopolysaccharide-induced activation of RAW264.7 macrophage cells
-
10.1016/j.bbrc.2010.01.009, 20060382
-
Gu H, Cui M, Bai Y, Chen F, Ma K, Zhou C, Guo L. Angiopoietin-1/Tie2 signaling pathway inhibits lipopolysaccharide-induced activation of RAW264.7 macrophage cells. Biochem Biophys Res Commun 2010, 392:178-182. 10.1016/j.bbrc.2010.01.009, 20060382.
-
(2010)
Biochem Biophys Res Commun
, vol.392
, pp. 178-182
-
-
Gu, H.1
Cui, M.2
Bai, Y.3
Chen, F.4
Ma, K.5
Zhou, C.6
Guo, L.7
-
32
-
-
37549020378
-
Surviving Sepsis Campaign: international guidelines for management of severe sepsis and septic shock: 2008
-
10.1097/01.CCM.0000298158.12101.41, 18158437
-
Dellinger RP, Levy MM, Carlet JM, Bion J, Parker MM, Jaeschke R, Reinhart K, Angus DC, Brun-Buisson C, Beale R, Calandra T, Dhainaut JF, Gerlach H, Harvey M, Marini JJ, Marshall J, Ranieri M, Ramsay G, Sevransky J, Thompson BT, Townsend S, Vender JS, Zimmerman JL, Vincent JL. Surviving Sepsis Campaign: international guidelines for management of severe sepsis and septic shock: 2008. Crit Care Med 2008, 36:296-327. 10.1097/01.CCM.0000298158.12101.41, 18158437.
-
(2008)
Crit Care Med
, vol.36
, pp. 296-327
-
-
Dellinger, R.P.1
Levy, M.M.2
Carlet, J.M.3
Bion, J.4
Parker, M.M.5
Jaeschke, R.6
Reinhart, K.7
Angus, D.C.8
Brun-Buisson, C.9
Beale, R.10
Calandra, T.11
Dhainaut, J.F.12
Gerlach, H.13
Harvey, M.14
Marini, J.J.15
Marshall, J.16
Ranieri, M.17
Ramsay, G.18
Sevransky, J.19
Thompson, B.T.20
Townsend, S.21
Vender, J.S.22
Zimmerman, J.L.23
Vincent, J.L.24
more..
-
33
-
-
33845905763
-
The disconnect between animal models of sepsis and human sepsis
-
Rittirsch D, Hoesel LM, Ward PA. The disconnect between animal models of sepsis and human sepsis. J Leukoc Biol 2007, 81:137-143.
-
(2007)
J Leukoc Biol
, vol.81
, pp. 137-143
-
-
Rittirsch, D.1
Hoesel, L.M.2
Ward, P.A.3
-
34
-
-
11144355412
-
Designed angiopoietin-1 variant, COMP-Ang1, protects against radiation-induced endothelial cell apoptosis
-
10.1073/pnas.0307575101, 397421, 15060280
-
Cho CH, Kammerer RA, Lee HJ, Yasunaga K, Kim KT, Choi HH, Kim W, Kim SH, Park SK, Lee GM, Koh GY. Designed angiopoietin-1 variant, COMP-Ang1, protects against radiation-induced endothelial cell apoptosis. Proc Natl Acad Sci USA 2004, 101:5553-5558. 10.1073/pnas.0307575101, 397421, 15060280.
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 5553-5558
-
-
Cho, C.H.1
Kammerer, R.A.2
Lee, H.J.3
Yasunaga, K.4
Kim, K.T.5
Choi, H.H.6
Kim, W.7
Kim, S.H.8
Park, S.K.9
Lee, G.M.10
Koh, G.Y.11
-
35
-
-
33644800621
-
Angiopoietin-1 decreases plasma leakage by reducing number and size of endothelial gaps in venules
-
Baffert F, Le T, Thurston G, McDonald DM. Angiopoietin-1 decreases plasma leakage by reducing number and size of endothelial gaps in venules. Am J Physiol Heart Circ Physiol 2006, 290:H107-H118.
-
(2006)
Am J Physiol Heart Circ Physiol
, vol.290
-
-
Baffert, F.1
Le, T.2
Thurston, G.3
McDonald, D.M.4
-
36
-
-
0034730784
-
Angiopoietin-1 is an antipermeability and anti-inflammatory agent in vitro and targets cell junctions
-
Gamble JR, Drew J, Trezise L, Underwood A, Parsons M, Kasminkas L, Rudge J, Yancopoulos G, Vadas MA. Angiopoietin-1 is an antipermeability and anti-inflammatory agent in vitro and targets cell junctions. Circ Res 2000, 87:603-607.
-
(2000)
Circ Res
, vol.87
, pp. 603-607
-
-
Gamble, J.R.1
Drew, J.2
Trezise, L.3
Underwood, A.4
Parsons, M.5
Kasminkas, L.6
Rudge, J.7
Yancopoulos, G.8
Vadas, M.A.9
-
37
-
-
0006677050
-
Angiopoietin-1 regulates endothelial cell survival through the phosphatidylinositol 3'-Kinase/Akt signal transduction pathway
-
Kim I, Kim HG, So JN, Kim JH, Kwak HJ, Koh GY. Angiopoietin-1 regulates endothelial cell survival through the phosphatidylinositol 3'-Kinase/Akt signal transduction pathway. Circ Res 2000, 86:24-29.
-
(2000)
Circ Res
, vol.86
, pp. 24-29
-
-
Kim, I.1
Kim, H.G.2
So, J.N.3
Kim, J.H.4
Kwak, H.J.5
Koh, G.Y.6
-
38
-
-
79958231061
-
Effects of a synthetic PEG-ylated Tie-2 agonist peptide on endotoxemic lung injury and mortality
-
10.1152/ajplung.00459.2010, 21421750
-
David S, Ghosh CC, Kümpers P, Shushakova N, Van Slyke P, Khankin EV, Karumanchi SA, Dumont D, Parikh SM. Effects of a synthetic PEG-ylated Tie-2 agonist peptide on endotoxemic lung injury and mortality. Am J Physiol Lung Cell Mol Physiol 2011, 300:L851-862. 10.1152/ajplung.00459.2010, 21421750.
-
(2011)
Am J Physiol Lung Cell Mol Physiol
, vol.300
-
-
David, S.1
Ghosh, C.C.2
Kümpers, P.3
Shushakova, N.4
Van Slyke, P.5
Khankin, E.V.6
Karumanchi, S.A.7
Dumont, D.8
Parikh, S.M.9
-
39
-
-
0035860845
-
Angiopoietin-1 reduces VEGF-stimulated leukocyte adhesion to endothelial cells by reducing ICAM-1, VCAM-1, and E-selectin expression
-
10.1161/hh1801.097034, 11557733
-
Kim I, Moon SO, Park SK, Chae SW, Koh GY. Angiopoietin-1 reduces VEGF-stimulated leukocyte adhesion to endothelial cells by reducing ICAM-1, VCAM-1, and E-selectin expression. Circ Res 2001, 89:477-479. 10.1161/hh1801.097034, 11557733.
-
(2001)
Circ Res
, vol.89
, pp. 477-479
-
-
Kim, I.1
Moon, S.O.2
Park, S.K.3
Chae, S.W.4
Koh, G.Y.5
-
40
-
-
78650763375
-
Angiopoietin-1 treatment reduces inflammation but does not prevent ventilator-induced lung injury
-
10.1371/journal.pone.0015653, 3001877, 21179479
-
Hegeman MA, Hennus MP, van MM, Cobelens PM, Kavelaars A, Jansen NJ, Schultz MJ, van Vught AJ, Molema G, Heijnen CJ. Angiopoietin-1 treatment reduces inflammation but does not prevent ventilator-induced lung injury. PLoS One 2010, 5:e15653. 10.1371/journal.pone.0015653, 3001877, 21179479.
-
(2010)
PLoS One
, vol.5
-
-
Hegeman, M.A.1
Hennus, M.P.2
van, M.M.3
Cobelens, P.M.4
Kavelaars, A.5
Jansen, N.J.6
Schultz, M.J.7
van Vught, A.J.8
Molema, G.9
Heijnen, C.J.10
-
41
-
-
38049141251
-
Blockade of airway inflammation and hyper-responsiveness by an angiopoietin-1 variant, COMP-Ang1
-
Lee KS, Lee KY, Kim SR, Park HS, Park SJ, Min KH, Cho CH, Koh GY, Park HS, Lee YC. Blockade of airway inflammation and hyper-responsiveness by an angiopoietin-1 variant, COMP-Ang1. Exp Mol Med 2007, 39:733-745.
-
(2007)
Exp Mol Med
, vol.39
, pp. 733-745
-
-
Lee, K.S.1
Lee, K.Y.2
Kim, S.R.3
Park, H.S.4
Park, S.J.5
Min, K.H.6
Cho, C.H.7
Koh, G.Y.8
Park, H.S.9
Lee, Y.C.10
-
42
-
-
33947650613
-
Angiopoietin chemotactic activities on neutrophils are regulated by PI-3K activation
-
10.1189/jlb.0906580, 17215522
-
Brkovic A, Pelletier M, Girard D, Sirois MG. Angiopoietin chemotactic activities on neutrophils are regulated by PI-3K activation. J Leukoc Biol 2007, 81:1093-1101. 10.1189/jlb.0906580, 17215522.
-
(2007)
J Leukoc Biol
, vol.81
, pp. 1093-1101
-
-
Brkovic, A.1
Pelletier, M.2
Girard, D.3
Sirois, M.G.4
-
43
-
-
23744515999
-
Angiopoietin affects neutrophil migration
-
10.1080/10739680590960296, 16020388
-
Sturn DH, Feistritzer C, Mosheimer BA, Djanani A, Bijuklic K, Patsch JR, Wiedermann CJ. Angiopoietin affects neutrophil migration. Microcirculation 2005, 12:393-403. 10.1080/10739680590960296, 16020388.
-
(2005)
Microcirculation
, vol.12
, pp. 393-403
-
-
Sturn, D.H.1
Feistritzer, C.2
Mosheimer, B.A.3
Djanani, A.4
Bijuklic, K.5
Patsch, J.R.6
Wiedermann, C.J.7
-
44
-
-
13544249614
-
Angiopoietins can directly activate endothelial cells and neutrophils to promote proinflammatory responses
-
10.1182/blood-2004-09-3531, 15498854
-
Lemieux C, Maliba R, Favier J, Theoret JF, Merhi Y, Sirois MG. Angiopoietins can directly activate endothelial cells and neutrophils to promote proinflammatory responses. Blood 2005, 105:1523-1530. 10.1182/blood-2004-09-3531, 15498854.
-
(2005)
Blood
, vol.105
, pp. 1523-1530
-
-
Lemieux, C.1
Maliba, R.2
Favier, J.3
Theoret, J.F.4
Merhi, Y.5
Sirois, M.G.6
-
45
-
-
0035010969
-
Defense mechanisms of the peritoneal cavity
-
10.1097/00075198-200104000-00009, 11373519
-
Broche F, Tellado JM. Defense mechanisms of the peritoneal cavity. Curr Opin Crit Care 2001, 7:105-116. 10.1097/00075198-200104000-00009, 11373519.
-
(2001)
Curr Opin Crit Care
, vol.7
, pp. 105-116
-
-
Broche, F.1
Tellado, J.M.2
-
46
-
-
59849086542
-
Alteration of microvascular permeability in acute kidney injury
-
10.1016/j.mvr.2008.09.004, 2680138, 18938184
-
Sutton TA. Alteration of microvascular permeability in acute kidney injury. Microvasc Res 2009, 77:4-7. 10.1016/j.mvr.2008.09.004, 2680138, 18938184.
-
(2009)
Microvasc Res
, vol.77
, pp. 4-7
-
-
Sutton, T.A.1
-
47
-
-
11144357304
-
COMP-Ang1: a designed angiopoietin-1 variant with nonleaky angiogenic activity
-
10.1073/pnas.0307574101, 397420, 15060279
-
Cho CH, Kammerer RA, Lee HJ, Steinmetz MO, Ryu YS, Lee SH, Yasunaga K, Kim KT, Kim I, Choi HH, Kim W, Kim SH, Park SK, Lee GM, Koh GY. COMP-Ang1: a designed angiopoietin-1 variant with nonleaky angiogenic activity. Proc Natl Acad Sci USA 2004, 101:5547-5552. 10.1073/pnas.0307574101, 397420, 15060279.
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 5547-5552
-
-
Cho, C.H.1
Kammerer, R.A.2
Lee, H.J.3
Steinmetz, M.O.4
Ryu, Y.S.5
Lee, S.H.6
Yasunaga, K.7
Kim, K.T.8
Kim, I.9
Choi, H.H.10
Kim, W.11
Kim, S.H.12
Park, S.K.13
Lee, G.M.14
Koh, G.Y.15
-
48
-
-
67349263020
-
A designed angiopoietin-2 variant, pentameric COMP-Ang2, strongly activates Tie2 receptor and stimulates angiogenesis
-
10.1016/j.bbamcr.2009.01.018, 19339208
-
Kim HZ, Jung K, Kim HM, Cheng Y, Koh GY. A designed angiopoietin-2 variant, pentameric COMP-Ang2, strongly activates Tie2 receptor and stimulates angiogenesis. Biochim Biophys Acta 2009, 1793:772-780. 10.1016/j.bbamcr.2009.01.018, 19339208.
-
(2009)
Biochim Biophys Acta
, vol.1793
, pp. 772-780
-
-
Kim, H.Z.1
Jung, K.2
Kim, H.M.3
Cheng, Y.4
Koh, G.Y.5
-
49
-
-
68049110523
-
Shock induced stress induces loss of microvascular endothelial Tie2 in the kidney which is not associated with reduced glomerular barrier function
-
10.1152/ajprenal.00137.2009, 19515812
-
van Meurs M, Kurniati NF, Wulfert F, Asgeirsdottir SA, de Graaf IA, Satchell SC, Mathieson PW, Jongman RM, Kümpers P, Zijlstra JG, Heeringa P, Molema G. Shock induced stress induces loss of microvascular endothelial Tie2 in the kidney which is not associated with reduced glomerular barrier function. Am J Physiol Renal Physiol 2009, 297:F272-F281. 10.1152/ajprenal.00137.2009, 19515812.
-
(2009)
Am J Physiol Renal Physiol
, vol.297
-
-
van Meurs, M.1
Kurniati, N.F.2
Wulfert, F.3
Asgeirsdottir, S.A.4
de Graaf, I.A.5
Satchell, S.C.6
Mathieson, P.W.7
Jongman, R.M.8
Kümpers, P.9
Zijlstra, J.G.10
Heeringa, P.11
Molema, G.12
-
50
-
-
45849146933
-
Regulation of angiopoietin expression by bacterial lipopolysaccharide
-
10.1152/ajplung.00449.2007, 18310225
-
Mofarrahi M, Nouh T, Qureshi S, Guillot L, Mayaki D, Hussain SN. Regulation of angiopoietin expression by bacterial lipopolysaccharide. Am J Physiol Lung Cell Mol Physiol 2008, 294:L955-L963. 10.1152/ajplung.00449.2007, 18310225.
-
(2008)
Am J Physiol Lung Cell Mol Physiol
, vol.294
-
-
Mofarrahi, M.1
Nouh, T.2
Qureshi, S.3
Guillot, L.4
Mayaki, D.5
Hussain, S.N.6
-
51
-
-
77149131838
-
The interaction of soluble Tie2 with angiopoietins and pulmonary vascular permeability in septic and nonseptic critically ill patients
-
10.1097/SHK.0b013e3181b2f978, 19543148
-
van der Heijden M, van Nieuw Amerongen GP, van Hinsbergh VW, Groeneveld AB. The interaction of soluble Tie2 with angiopoietins and pulmonary vascular permeability in septic and nonseptic critically ill patients. Shock 2010, 33:263-268. 10.1097/SHK.0b013e3181b2f978, 19543148.
-
(2010)
Shock
, vol.33
, pp. 263-268
-
-
van der Heijden, M.1
van Nieuw Amerongen, G.P.2
van Hinsbergh, V.W.3
Groeneveld, A.B.4
|