Manipulation of endogenous kinase activity in living cells using photoswitchable inhibitory peptides

ACS Synthetic Biology

Volumn 3, Issue 11, 2014, Pages 788-795

  Yi, Jason J ^a   Wang, Hui ^a   Vilela, Marco ^b   Danuser, Gaudenz ^b   Hahn, Klaus M ^a  

^a UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

Author keywords

CREB; Membrane dynamics; MLCK; Optogenetics; Peptide caging; PKA

Indexed keywords

CYCLIC AMP DEPENDENT PROTEIN KINASE; MYOSIN LIGHT CHAIN KINASE; PEPTIDE DERIVATIVE; PHOSPHOTRANSFERASE; PHOSPHOTRANSFERASE INHIBITOR; PEPTIDE; PHOTOTROPIN; PROTEIN KINASE INHIBITOR;

ANIMAL CELL; ARTICLE; CELL FUNCTION; ENZYME ACTIVITY; ENZYME INHIBITION; IMMUNOHISTOCHEMISTRY; MOUSE; NERVE CELL CULTURE; NONHUMAN; PROTEIN DOMAIN; PROTEIN PHOSPHORYLATION; PROTEIN STRUCTURE; SIGNAL TRANSDUCTION; ANIMAL; AVENA; CELL MEMBRANE; CHEMICAL STRUCTURE; CHEMISTRY; CHLOROCEBUS AETHIOPS; COS 1 CELL LINE; GENETICS; METABOLISM; OPTOGENETICS; PHOTOBIOLOGY; RADIATION RESPONSE;

ANIMALS; AVENA; CELL MEMBRANE; CERCOPITHECUS AETHIOPS; COS CELLS; CYCLIC AMP-DEPENDENT PROTEIN KINASES; MODELS, MOLECULAR; MYOSIN-LIGHT-CHAIN KINASE; OPTOGENETICS; PEPTIDES; PHOTOBIOLOGY; PHOTOTROPINS; PROTEIN KINASE INHIBITORS;

EID: 84908057379     PISSN: None     EISSN: 21615063     Source Type: Journal    
DOI: 10.1021/sb5001356     Document Type: Article

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