Inhibition of autophagy by 3-MA potentiates purvalanol-induced apoptosis in Bax deficient HCT 116 colon cancer cells

Experimental Cell Research

Volumn 328, Issue 1, 2014, Pages 87-98

  Coker Gurkan, Ajda ^a   Arisan, Elif Damla ^a   Obakan, Pinar ^a   Guvenir, Esin ^a   Unsal, Narcin Palavan ^a  

^a ISTANBUL KULTUR UNIVERSITY   (Turkey)

Author keywords

Apoptosis; Autophagy; Bax; CDK inhibitors; Colon cancer

Indexed keywords

3 METHYLADENINE; BECLIN 1; CASPASE 3; CASPASE 7; CASPASE 9; CYCLIN B1; CYCLIN E; PROTEIN BAX; PROTEIN BCL 2; PROTEIN P53; PURVALANOL; ROSCOVITINE; 3 METHYLCHOLANTHRENE; 6-((3-CHLORO)ANILINO)-2-(ISOPROPYL-2-HYDROXYETHYLAMINO)-9-ISOPROPYLPURINE; ANTINEOPLASTIC AGENT; BAX PROTEIN, HUMAN; CYCLIN DEPENDENT KINASE; CYCLIN DEPENDENT KINASE 1; PURINE DERIVATIVE;

APOPTOSIS; ARTICLE; AUTOPHAGY; CANCER CELL; CANCER INHIBITION; CANCER RESISTANCE; CELL CYCLE ARREST; CELL CYCLE PROGRESSION; CELL CYCLE REGULATION; CELL PROLIFERATION; CELL SURVIVAL; CELL VACUOLE; CELL VIABILITY; COLON CANCER; CONTROLLED STUDY; DRUG MECHANISM; DRUG POTENTIATION; ENZYME ACTIVITY; HUMAN; HUMAN CELL; MITOCHONDRIAL MEMBRANE POTENTIAL; PROTEIN DEPHOSPHORYLATION; PROTEIN EXPRESSION; UPREGULATION; ANTAGONISTS AND INHIBITORS; CELL CYCLE; COLONIC NEOPLASMS; DRUG EFFECTS; ENZYME LINKED IMMUNOSORBENT ASSAY; FLOW CYTOMETRY; IMMUNOPRECIPITATION; METABOLISM; PATHOLOGY; TUMOR CELL CULTURE; WESTERN BLOTTING;

ANTINEOPLASTIC AGENTS; APOPTOSIS; AUTOPHAGY; BCL-2-ASSOCIATED X PROTEIN; BLOTTING, WESTERN; CDC2 PROTEIN KINASE; CELL CYCLE; CELL PROLIFERATION; COLONIC NEOPLASMS; CYCLIN-DEPENDENT KINASES; DRUG SYNERGISM; ENZYME-LINKED IMMUNOSORBENT ASSAY; FLOW CYTOMETRY; HUMANS; IMMUNOPRECIPITATION; MEMBRANE POTENTIAL, MITOCHONDRIAL; METHYLCHOLANTHRENE; PURINES; TUMOR CELLS, CULTURED;

EID: 84908051096     PISSN: 00144827     EISSN: 10902422     Source Type: Journal    
DOI: 10.1016/j.yexcr.2014.07.022     Document Type: Article

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