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Bioorganic and Medicinal Chemistry Letters

Volumn 24, Issue 21, 2014, Pages 4948-4953

Synthesis and preliminary investigations into novel 1,2,3-triazole-derived androgen receptor antagonists inspired by bicalutamide

(6) Altimari, Jarrad M a Niranjan, Birunthi b Risbridger, Gail P b Schweiker, Stephanie S c Lohning, Anna E c Henderson, Luke C a

a DEAKIN UNIVERSITY (Australia)

b MONASH UNIVERSITY (Australia)

c BOND UNIVERSITY (Australia)

Author keywords

Androgen receptor; Bicalutamide; Click chemistry; Molecular modeling; Prostate cancer; Triazole

Indexed keywords

1,2,3 TRIAZOLE DERIVATIVE; ANDROGEN RECEPTOR ANTAGONIST; ANTINEOPLASTIC AGENT; BICALUTAMIDE; ANDROGEN RECEPTOR; ANILIDE; ANTIANDROGEN; AR PROTEIN, HUMAN; NITRILE; TOLUENESULFONIC ACID DERIVATIVE; TRIAZOLE DERIVATIVE;

ANTINEOPLASTIC ACTIVITY; ANTIPROLIFERATIVE ACTIVITY; ARTICLE; CANCER CELL; CONTROLLED STUDY; DRUG BINDING; DRUG DESIGN; DRUG SYNTHESIS; ENANTIOMER; HUMAN; HUMAN CELL; HYDROGEN BOND; MALE; MOLECULAR DOCKING; PROSTATE CANCER; STEREOCHEMISTRY; STEREOISOMERISM; STEROID BINDING; CELL SURVIVAL; CHEMISTRY; DRUG EFFECTS; METABOLISM; PROSTATIC NEOPLASMS; SYNTHESIS; TUMOR CELL CULTURE;

ANDROGEN ANTAGONISTS; ANDROGEN RECEPTOR ANTAGONISTS; ANILIDES; CELL SURVIVAL; HUMANS; MALE; NITRILES; PROSTATIC NEOPLASMS; RECEPTORS, ANDROGEN; TOSYL COMPOUNDS; TRIAZOLES; TUMOR CELLS, CULTURED;

EID: 84908012117 PISSN: 0960894X EISSN: 14643405 Source Type: Journal
DOI: 10.1016/j.bmcl.2014.09.036 Document Type: Article

Times cited : (9)

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