메뉴 건너뛰기




Volumn 88, Issue 21, 2014, Pages 12438-12451

Kinetic and phenotypic analysis of CD8+ T cell responses after priming with alphavirus replicons and homologous or heterologous booster immunizations

Author keywords

[No Author keywords available]

Indexed keywords

CD27 ANTIGEN; INTERLEUKIN 7 RECEPTOR; L SELECTIN; LEUKOSIALIN; POXVIRUS VECTOR; VIRUS DNA; DNA VACCINE; VIRUS VACCINE;

EID: 84908005427     PISSN: 0022538X     EISSN: 10985514     Source Type: Journal    
DOI: 10.1128/JVI.02223-14     Document Type: Article
Times cited : (27)

References (74)
  • 3
    • 80053004837 scopus 로고    scopus 로고
    • + T-cell immunity: focus on recombinant adenovirus vectors
    • + T-cell immunity: focus on recombinant adenovirus vectors. Expert Rev. Vaccines 10:1307-1319. http://dx.doi.org/10.1586/erv.11.88.
    • (2011) Expert Rev. Vaccines , vol.10 , pp. 1307-1319
    • Bassett, J.D.1    Swift, S.L.2    Bramson, J.L.3
  • 6
    • 84867896903 scopus 로고    scopus 로고
    • + T cell differentiation
    • + T cell differentiation. Nat. Rev. Immunol. 12:749-761. http://dx.doi.org/10.1038/nri3307.
    • (2012) Nat. Rev. Immunol. , vol.12 , pp. 749-761
    • Kaech, S.M.1    Cui, W.2
  • 7
    • 77958492018 scopus 로고    scopus 로고
    • From vaccines to memory and back
    • Sallusto F, Lanzavecchia A, Araki K, Ahmed R. 2010. From vaccines to memory and back. Immunity 33:451-463. http://dx.doi.org/10.1016/j.immuni.2010.10.008.
    • (2010) Immunity , vol.33 , pp. 451-463
    • Sallusto, F.1    Lanzavecchia, A.2    Araki, K.3    Ahmed, R.4
  • 8
    • 0033554726 scopus 로고    scopus 로고
    • Two subsets of memory T lymphocytes with distinct homing potentials and effector functions
    • Sallusto F, Lenig D, Förster R, Lipp M, Lanzavecchia A. 1999. Two subsets of memory T lymphocytes with distinct homing potentials and effector functions. Nature 401:708-712. http://dx.doi.org/10.1038/44385.
    • (1999) Nature , vol.401 , pp. 708-712
    • Sallusto, F.1    Lenig, D.2    Förster, R.3    Lipp, M.4    Lanzavecchia, A.5
  • 9
    • 0035937587 scopus 로고    scopus 로고
    • Preferential localization of effector memory cells in nonlymphoid tissue
    • Masopust D, Vezys V, Marzo AL, Lefrançois L. 2001. Preferential localization of effector memory cells in nonlymphoid tissue. Science 291: 2413-2417. http://dx.doi.org/10.1126/science.1058867.
    • (2001) Science , vol.291 , pp. 2413-2417
    • Masopust, D.1    Vezys, V.2    Marzo, A.L.3    Lefrançois, L.4
  • 10
    • 25444461647 scopus 로고    scopus 로고
    • + T cell subsets identified by expression of IL-7 receptor alpha and CD62L
    • + T cell subsets identified by expression of IL-7 receptor alpha and CD62L. J. Immunol. 175:4686-4696 http://dx.doi.org/10.4049/jimmunol.175.7.4686.
    • (2005) J. Immunol. , vol.175 , pp. 4686-4696
    • Bachmann, M.F.1    Wolint, P.2    Schwarz, K.3    Jäger, P.4    Oxenius, A.5
  • 13
    • 79956320655 scopus 로고    scopus 로고
    • + T cells is dictated by antigen exposure history and nature of the infection
    • + T cells is dictated by antigen exposure history and nature of the infection. Immunity 34:781-793. http://dx.doi.org/10.1016/j.immuni.2011.03.020.
    • (2011) Immunity , vol.34 , pp. 781-793
    • Nolz, J.C.1    Harty, J.T.2
  • 17
    • 79951833033 scopus 로고    scopus 로고
    • + T cell responses with an adenoviral vectorbased hepatitis C virus vaccine encoding NS3 linked to the MHC class II chaperone protein invariant chain
    • + T cell responses with an adenoviral vectorbased hepatitis C virus vaccine encoding NS3 linked to the MHC class II chaperone protein invariant chain. J. Immunol. 186:2355-2364. http://dx.doi.org/10.4049/jimmunol.1001877.
    • (2011) J. Immunol. , vol.186 , pp. 2355-2364
    • Mikkelsen, M.1    Holst, P.J.2    Bukh, J.3    Thomsen, A.R.4    Christensen, J.P.5
  • 18
    • 34249782279 scopus 로고    scopus 로고
    • Comparative primeboost vaccinations using Semliki Forest virus, adenovirus, and ALVAC vectors demonstrate differences in the generation of a protective central memory CTL response against the P815 tumor
    • Näslund TI, Uyttenhove C, Nordström EKL, Colau D, Warnier G, Jondal M, Van den Eynde BJ, Liljeström P. 2007. Comparative primeboost vaccinations using Semliki Forest virus, adenovirus, and ALVAC vectors demonstrate differences in the generation of a protective central memory CTL response against the P815 tumor. J. Immunol. 178:6761-6769 http://dx.doi.org/10.4049/jimmunol.178.11.6761.
    • (2007) J. Immunol. , vol.178 , pp. 6761-6769
    • Näslund, T.I.1    Uyttenhove, C.2    Nordström, E.K.L.3    Colau, D.4    Warnier, G.5    Jondal, M.6    Van den Eynde, B.J.7    Liljeström, P.8
  • 20
    • 84894565637 scopus 로고    scopus 로고
    • A novel poxvirus-based vaccine, MVA-CHIKV, is highly immunogenic and protects mice against Chikungunya infection
    • García-Arriaza J, Cepeda V, Hallengärd D, Sorzano CóS, Kümmerer BM, Liljeström P, Esteban M. 2014. A novel poxvirus-based vaccine, MVA-CHIKV, is highly immunogenic and protects mice against Chikungunya infection. J. Virol. 88:3527-3547. http://dx.doi.org/10.1128/JVI.03418-13.
    • (2014) J. Virol. , vol.88 , pp. 3527-3547
    • García-Arriaza, J.1    Cepeda, V.2    Hallengärd, D.3    Sorzano, CóS.4    Kümmerer, B.M.5    Liljeström, P.6    Esteban, M.7
  • 22
    • 0032906979 scopus 로고    scopus 로고
    • Two-helper RNA system for production of recombinant Semliki Forest virus particles
    • Smerdou C, Liljeström P. 1999. Two-helper RNA system for production of recombinant Semliki Forest virus particles. J. Virol. 73:1092-1098.
    • (1999) J. Virol. , vol.73 , pp. 1092-1098
    • Smerdou, C.1    Liljeström, P.2
  • 23
  • 24
    • 0028152741 scopus 로고
    • A significantly improved Semliki Forest virus expression system based on translation enhancer segments from the viral capsid gene
    • Sjöberg EM, Suomalainen M, Garoff H. 1994. A significantly improved Semliki Forest virus expression system based on translation enhancer segments from the viral capsid gene. Biotechnology 12:1127-1131. http://dx.doi.org/10.1038/nbt1194-1127.
    • (1994) Biotechnology , vol.12 , pp. 1127-1131
    • Sjöberg, E.M.1    Suomalainen, M.2    Garoff, H.3
  • 25
    • 0028058011 scopus 로고
    • Foot-and-mouth disease virus 2A oligopeptide mediated cleavage of an artificial polyprotein
    • Ryan MD, Drew J. 1994. Foot-and-mouth disease virus 2A oligopeptide mediated cleavage of an artificial polyprotein. EMBO J. 13:928-933.
    • (1994) EMBO J. , vol.13 , pp. 928-933
    • Ryan, M.D.1    Drew, J.2
  • 26
    • 0035015174 scopus 로고    scopus 로고
    • Analysis of the aphthovirus 2A/2B polyprotein "cleavage" mechanism indicates not a proteolytic reaction, but a novel translational effect: a putative ribosomal "skip." J
    • Donnelly ML, Luke G, Mehrotra A, Li X, Hughes LE, Gani D, Ryan MD. 2001. Analysis of the aphthovirus 2A/2B polyprotein "cleavage" mechanism indicates not a proteolytic reaction, but a novel translational effect: a putative ribosomal "skip." J. Gen. Virol. 82:1013-1025.
    • (2001) Gen. Virol. , vol.82 , pp. 1013-1025
    • Donnelly, M.L.1    Luke, G.2    Mehrotra, A.3    Li, X.4    Hughes, L.E.5    Gani, D.6    Ryan, M.D.7
  • 27
    • 83655212354 scopus 로고    scopus 로고
    • Inhibitors of alphavirus entry and replication identified with a stable Chikungunya replicon cell line and virus-based assays
    • Pohjala L, Utt A, Varjak M, Lulla A, Merits A, Ahola T, Tammela P. 2011 Inhibitors of alphavirus entry and replication identified with a stable Chikungunya replicon cell line and virus-based assays. PLoS One 6:e28923. http://dx.doi.org/10.1371/journal.pone.0028923.
    • (2011) PLoS One , vol.6
    • Pohjala, L.1    Utt, A.2    Varjak, M.3    Lulla, A.4    Merits, A.5    Ahola, T.6    Tammela, P.7
  • 32
    • 0038665308 scopus 로고    scopus 로고
    • + T cells undergoing primary and secondary responses to infection in the same host
    • + T cells undergoing primary and secondary responses to infection in the same host. J. Immunol. 170:4933-4942. http://dx.doi.org /10.4049/jimmunol.170.10.4933.
    • (2003) J. Immunol. , vol.170 , pp. 4933-4942
    • Badovinac, V.P.1    Messingham, K.A.2    Hamilton, S.E.3    Harty, J.T.4
  • 33
    • 0035865371 scopus 로고    scopus 로고
    • Direct analysis of the dynamics of the intestinal mucosa CD8 T cell response to systemic virus infection
    • Masopust D, Jiang J, Shen H, Lefrançois L. 2001. Direct analysis of the dynamics of the intestinal mucosa CD8 T cell response to systemic virus infection. J. Immunol. 166:2348-2356. http://dx.doi.org/10.4049/jimmunol.166.4.2348.
    • (2001) J. Immunol. , vol.166 , pp. 2348-2356
    • Masopust, D.1    Jiang, J.2    Shen, H.3    Lefrançois, L.4
  • 34
    • 33745810216 scopus 로고    scopus 로고
    • Stimulation history dictates memory CD8 T cell phenotype: implications for prime-boost vaccination
    • Masopust D, Ha S-J, Vezys V, Ahmed R. 2006. Stimulation history dictates memory CD8 T cell phenotype: implications for prime-boost vaccination. J. Immunol. 177:831-839. http://dx.doi.org/10.4049/jimmunol.177.2.831.
    • (2006) J. Immunol. , vol.177 , pp. 831-839
    • Masopust, D.1    Ha, S.-J.2    Vezys, V.3    Ahmed, R.4
  • 36
    • 33645843343 scopus 로고    scopus 로고
    • + T cells are more protective but slower to acquire a central-memory phenotype
    • + T cells are more protective but slower to acquire a central-memory phenotype. J. Exp. Med. 203:919-932. http://dx.doi.org/10.1084/jem.20052237.
    • (2006) J. Exp. Med. , vol.203 , pp. 919-932
    • Jabbari, A.1    Harty, J.T.2
  • 37
    • 23844478428 scopus 로고    scopus 로고
    • Type I interferons potently suppress gene expression following gene delivery using liposome(-)DNA complexes
    • Sellins K, Fradkin L, Liggitt D, Dow S. 2005. Type I interferons potently suppress gene expression following gene delivery using liposome(-)DNA complexes. Mol. Ther. 12:451-459. http://dx.doi.org/10.1016/j.ymthe.2005.04.008.
    • (2005) Mol. Ther. , vol.12 , pp. 451-459
    • Sellins, K.1    Fradkin, L.2    Liggitt, D.3    Dow, S.4
  • 38
    • 78751644761 scopus 로고    scopus 로고
    • Role of innate signaling pathways in the immunogenicity of alphaviral replicon-based vaccines
    • Näslund TI, Kostic L, Nordström EK, Chen M, Liljeström P. 2011. Role of innate signaling pathways in the immunogenicity of alphaviral replicon-based vaccines. Virol. J. 8:36. http://dx.doi.org/10.1186/1743-422X-8-36.
    • (2011) Virol. J. , vol.8 , pp. 36
    • Näslund, T.I.1    Kostic, L.2    Nordström, E.K.3    Chen, M.4    Liljeström, P.5
  • 40
    • 33745091465 scopus 로고    scopus 로고
    • Functional signatures of protective antiviral T-cell immunity in human virus infections
    • Harari A, Dutoit V, Cellerai C, Bart PA, Du Pasquier RA, Pantaleo G. 2006 Functional signatures of protective antiviral T-cell immunity in human virus infections. Immunol. Rev. 211:236-254. http://dx.doi.org/10.1111/j.0105-2896.2006.00395.x.
    • (2006) Immunol. Rev. , vol.211 , pp. 236-254
    • Harari, A.1    Dutoit, V.2    Cellerai, C.3    Bart, P.A.4    Du Pasquier, R.A.5    Pantaleo, G.6
  • 41
    • 0030859122 scopus 로고    scopus 로고
    • Sequence analysis of the avirulent, demyelinating A7 strain of Semliki Forest virus
    • Tarbatt CJ, Glasgow GM, Mooney DA, Sheahan BJ, Atkins GJ. 1997. Sequence analysis of the avirulent, demyelinating A7 strain of Semliki Forest virus. J. Gen. Virol. 78(Pt 7):1551-1557.
    • (1997) J. Gen. Virol. , vol.78 , pp. 1551-1557
    • Tarbatt, C.J.1    Glasgow, G.M.2    Mooney, D.A.3    Sheahan, B.J.4    Atkins, G.J.5
  • 42
    • 77958469466 scopus 로고    scopus 로고
    • Immunologic basis of vaccine vectors
    • Liu MA. 2010. Immunologic basis of vaccine vectors. Immunity 33:504-515 http://dx.doi.org/10.1016/j.immuni.2010.10.004.
    • (2010) Immunity , vol.33 , pp. 504-515
    • Liu, M.A.1
  • 44
    • 84880756431 scopus 로고    scopus 로고
    • + T cells favor rapid memory differentiation and preservation of proliferative potential upon boosting
    • + T cells favor rapid memory differentiation and preservation of proliferative potential upon boosting. Immunity 39:171-183. http://dx.doi.org/10.1016/j.immuni.2013.07.003.
    • (2013) Immunity , vol.39 , pp. 171-183
    • Fraser, K.A.1    Schenkel, J.M.2    Jameson, S.C.3    Vezys, V.4    Masopust, D.5
  • 46
    • 84874244299 scopus 로고    scopus 로고
    • Temporal dynamics of the primary human T cell response to yellow fever virus 17D as it matures from an effector-to a memory-type response
    • Blom K, Braun M, Ivarsson MA, Gonzalez VD, Falconer K, Moll M, Ljunggren H-G, Michaëlsson J, Sandberg JK. 2013. Temporal dynamics of the primary human T cell response to yellow fever virus 17D as it matures from an effector-to a memory-type response. J. Immunol. 190: 2150-2158. http://dx.doi.org/10.4049/jimmunol.1202234.
    • (2013) J. Immunol. , vol.190 , pp. 2150-2158
    • Blom, K.1    Braun, M.2    Ivarsson, M.A.3    Gonzalez, V.D.4    Falconer, K.5    Moll, M.6    Ljunggren, H.-G.7    Michaëlsson, J.8    Sandberg, J.K.9
  • 49
    • 79960384537 scopus 로고    scopus 로고
    • Different patterns of expansion, contraction and memory differentiation of HIV-1 Gag-specific CD8 T cells elicited by adenovirus type 5 and modified vaccinia Ankara vaccines
    • Pillai VKB, Kannanganat S, Penaloza-Macmaster P, Chennareddi L, Robinson HL, Blackwell J, Amara RR. 2011. Different patterns of expansion, contraction and memory differentiation of HIV-1 Gag-specific CD8 T cells elicited by adenovirus type 5 and modified vaccinia Ankara vaccines. Vaccine 29:5399-5406. http://dx.doi.org/10.1016/j.vaccine.2011.05.083.
    • (2011) Vaccine , vol.29 , pp. 5399-5406
    • Pillai, V.K.B.1    Kannanganat, S.2    Penaloza-Macmaster, P.3    Chennareddi, L.4    Robinson, H.L.5    Blackwell, J.6    Amara, R.R.7
  • 50
    • 0035949705 scopus 로고    scopus 로고
    • Complete, long-lasting protection against malaria of mice primed and boosted with two distinct viral vectors expressing the same plasmodial antigen
    • Bruña-Romero O, González-Aseguinolaza G, Hafalla JC, Tsuji M, Nussenzweig RS. 2001. Complete, long-lasting protection against malaria of mice primed and boosted with two distinct viral vectors expressing the same plasmodial antigen. Proc. Natl. Acad. Sci. U. S. A. 98:11491-11496. http://dx.doi.org/10.1073/pnas.191380898.
    • (2001) Proc. Natl. Acad. Sci. U. S. A. , vol.98 , pp. 11491-11496
    • Bruña-Romero, O.1    González-Aseguinolaza, G.2    Hafalla, J.C.3    Tsuji, M.4    Nussenzweig, R.S.5
  • 52
    • 0033524647 scopus 로고    scopus 로고
    • Immunization with recombinant Semliki Forest virus induces protection against influenza challenge in mice
    • Berglund P, Fleeton MN, Smerdou C, Liljeström P. 1999. Immunization with recombinant Semliki Forest virus induces protection against influenza challenge in mice. Vaccine 17:497-507.
    • (1999) Vaccine , vol.17 , pp. 497-507
    • Berglund, P.1    Fleeton, M.N.2    Smerdou, C.3    Liljeström, P.4
  • 54
    • 0031583842 scopus 로고    scopus 로고
    • Replicon-helper systems from attenuated Venezuelan equine encephalitis virus: expression of heterologous genes in vitro and immunization against heterologous pathogens in vivo
    • Pushko P, Parker M, Ludwig GV, Davis NL, Johnston RE, Smith JF. 1997 Replicon-helper systems from attenuated Venezuelan equine encephalitis virus: expression of heterologous genes in vitro and immunization against heterologous pathogens in vivo. Virology 239:389-401. http: //dx.doi.org/10.1006/viro.1997.8878.
    • (1997) Virology , vol.239 , pp. 389-401
    • Pushko, P.1    Parker, M.2    Ludwig, G.V.3    Davis, N.L.4    Johnston, R.E.5    Smith, J.F.6
  • 57
    • 34548694962 scopus 로고    scopus 로고
    • Innate recognition of viruses
    • Pichlmair A, Reis e Sousa C. 2007. Innate recognition of viruses. Immunity 27:370-383. http://dx.doi.org/10.1016/j.immuni.2007.08.012.
    • (2007) Immunity , vol.27 , pp. 370-383
    • Pichlmair, A.1    Reis e Sousa, C.2
  • 58
    • 67649210620 scopus 로고    scopus 로고
    • PKR acts early in infection to suppress Semliki Forest virus production and strongly enhances the type I interferon response
    • Barry G, Breakwell L, Fragkoudis R, Attarzadeh-Yazdi G, Rodriguez-Andres J, Kohl A, Fazakerley JK. 2009. PKR acts early in infection to suppress Semliki Forest virus production and strongly enhances the type I interferon response. J. Gen. Virol. 90:1382-1391. http://dx.doi.org/10.1099/vir.0.007336-0.
    • (2009) J. Gen. Virol. , vol.90 , pp. 1382-1391
    • Barry, G.1    Breakwell, L.2    Fragkoudis, R.3    Attarzadeh-Yazdi, G.4    Rodriguez-Andres, J.5    Kohl, A.6    Fazakerley, J.K.7
  • 59
    • 23244439085 scopus 로고    scopus 로고
    • Early alpha/beta interferon production by myeloid dendritic cells in response to UVinactivated virus requires viral entry and interferon regulatory factor 3 but not MyD88
    • Hidmark AS, McInerney GM, Nordström EKL, Douagi I, Werner KM, Liljeström P, Karlsson-Hedestam GB. 2005. Early alpha/beta interferon production by myeloid dendritic cells in response to UVinactivated virus requires viral entry and interferon regulatory factor 3 but not MyD88. J. Virol. 79:10376-10385. http://dx.doi.org/10.1128 /JVI.79.16.10376-10385.2005.
    • (2005) J. Virol. , vol.79 , pp. 10376-10385
    • Hidmark, A.S.1    McInerney, G.M.2    Nordström, E.K.L.3    Douagi, I.4    Werner, K.M.5    Liljeström, P.6    Karlsson-Hedestam, G.B.7
  • 60
    • 0030760873 scopus 로고    scopus 로고
    • Death mechanisms in cultured cells infected by Semliki Forest virus
    • Glasgow GM, McGee MM, Sheahan BJ, Atkins GJ. 1997. Death mechanisms in cultured cells infected by Semliki Forest virus. J. Gen. Virol. 78(Pt 7):1559-1563.
    • (1997) J. Gen. Virol. , vol.78 , pp. 1559-1563
    • Glasgow, G.M.1    McGee, M.M.2    Sheahan, B.J.3    Atkins, G.J.4
  • 65
    • 84856354852 scopus 로고    scopus 로고
    • + T cell memory independent of IL-12 and type I IFN is dependent on CD27/OX40 signaling
    • + T cell memory independent of IL-12 and type I IFN is dependent on CD27/OX40 signaling. Vaccine 30:1154-1161. http://dx.doi.org/10.1016/j.vaccine.2011.12.017.
    • (2012) Vaccine , vol.30 , pp. 1154-1161
    • Sanchez, P.J.1    Kedl, R.M.2
  • 66
    • 64849085607 scopus 로고    scopus 로고
    • Programming for CD8 T cell memory development requires IL-12 or type I IFN
    • Xiao Z, Casey KA, Jameson SC, Curtsinger JM, Mescher MF. 2009. Programming for CD8 T cell memory development requires IL-12 or type I IFN. J. Immunol. 182:2786-2794. http://dx.doi.org/10.4049/jimmunol.0803484.
    • (2009) J. Immunol. , vol.182 , pp. 2786-2794
    • Xiao, Z.1    Casey, K.A.2    Jameson, S.C.3    Curtsinger, J.M.4    Mescher, M.F.5
  • 67
    • 0033583516 scopus 로고    scopus 로고
    • Two roads diverged: interferon alpha/beta-and interleukin 12-mediated pathways in promoting T cell interferon gamma responses during viral infection
    • Cousens LP, Peterson R, Hsu S, Dorner A, Altman JD, Ahmed R, Biron CA. 1999. Two roads diverged: interferon alpha/beta-and interleukin 12-mediated pathways in promoting T cell interferon gamma responses during viral infection. J. Exp. Med. 189:1315-1328. http://dx.doi.org/10.1084/jem.189.8.1315.
    • (1999) J. Exp. Med. , vol.189 , pp. 1315-1328
    • Cousens, L.P.1    Peterson, R.2    Hsu, S.3    Dorner, A.4    Altman, J.D.5    Ahmed, R.6    Biron, C.A.7
  • 68
    • 17644419950 scopus 로고    scopus 로고
    • T cell vaccines for microbial infections
    • Robinson HL, Amara RR. 2005. T cell vaccines for microbial infections. Nat. Med. 11:S25-S32. http://dx.doi.org/10.1038/nm1212.
    • (2005) Nat. Med. , vol.11 , pp. S25-S32
    • Robinson, H.L.1    Amara, R.R.2
  • 71
  • 73
    • 84862598313 scopus 로고    scopus 로고
    • Hidden memories: frontline memory T cells and early pathogen interception
    • Masopust D, Picker LJ. 2012. Hidden memories: frontline memory T cells and early pathogen interception. J. Immunol. 188:5811-5817. http: //dx.doi.org/10.4049/jimmunol.1102695.
    • (2012) J. Immunol. , vol.188 , pp. 5811-5817
    • Masopust, D.1    Picker, L.J.2
  • 74
    • 84897543043 scopus 로고    scopus 로고
    • Cutting edge: resident memory CD8 T cells occupy frontline niches in secondary lymphoid organs
    • Schenkel JM, Fraser KA, Masopust D. 2014. Cutting edge: resident memory CD8 T cells occupy frontline niches in secondary lymphoid organs. J. Immunol. 192:2961-2964. http://dx.doi.org/10.4049/jimmunol.1400003.
    • (2014) J. Immunol. , vol.192 , pp. 2961-2964
    • Schenkel, J.M.1    Fraser, K.A.2    Masopust, D.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.