CD8+ T effector memory cells protect against liver-stage malaria

Journal of Immunology

Volumn 187, Issue 3, 2011, Pages 1347-1357

  Reyes Sandoval, Arturo ^a   Wyllie, David H ^a   Bauza, Karolis ^a   Milicic, Anita ^a   Forbes, Emily K ^a   Rollier, Christine S ^a,b   Hill, Adrian V S ^a  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b CHURCHILL HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOVIRUS VECTOR; INTERLEUKIN 7 RECEPTOR; L SELECTIN; MALARIA VACCINE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIGEN SPECIFICITY; ARTICLE; CD8+ T LYMPHOCYTE; CENTRAL MEMORY T LYMPHOCYTE; CONTROLLED STUDY; EFFECTOR MEMORY T CELL; FEMALE; HEPATITIS; MALARIA; MOUSE; NONHUMAN; PLASMODIUM BERGHEI; PRIORITY JOURNAL; PROTECTION; SPOROZOITE; T LYMPHOCYTE; T LYMPHOCYTE SUBPOPULATION; VACCINATION;

ADENOVIRIDAE; ANIMALS; CD8-POSITIVE T-LYMPHOCYTES; EPITOPES, T-LYMPHOCYTE; FEMALE; GENETIC VECTORS; H-2 ANTIGENS; HUMANS; IMMUNOLOGIC MEMORY; LIVER DISEASES, PARASITIC; MALARIA; MALARIA VACCINES; MICE; MICE, INBRED BALB C; PLASMODIUM BERGHEI; PROTOZOAN PROTEINS; TRANSGENES; VACCINIA;

EID: 80051646256     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1100302     Document Type: Article

References (35)

1. Snow, R. W., C. A. Guerra, A. M. Noor, H. Y. Myint, and S. I. Hay. 2005. The global distribution of clinical episodes of Plasmodium falciparum malaria. Nature 434: 214-217. (Pubitemid 40388051)
2. Casares, S., T. D. Brumeanu, and T. L. Richie. 2010. The RTS,S malaria vaccine. Vaccine 28: 4880-4894.
3. Hill, A. V. 2006. Pre-erythrocytic malaria vaccines: towards greater efficacy. Nat. Rev. Immunol. 6: 21-32. (Pubitemid 43279750)
4. Webster, D. P., S. Dunachie, J. M. Vuola, T. Berthoud, S. Keating, S. M. Laidlaw, S. J. McConkey, I. Poulton, L. Andrews, R. F. Andersen, et al. 2005. Enhanced T cell-mediated protection against malaria in human challenges by using the recombinant poxviruses FP9 and modified vaccinia virus Ankara. Proc. Natl. Acad. Sci. USA 102: 4836-4841. (Pubitemid 40471540)
5. Hill, A. V., A. Reyes-Sandoval, G. O'Hara, K. Ewer, A. Lawrie, A. Goodman, A. Nicosia, A. Folgori, S. Colloca, R. Cortese, et al. 2010. Prime-boost vectored malaria vaccines: progress and prospects. Hum. Vaccin. 6: 78-83.
6. Moorthy, V. S., and W. R. Ballou. 2009. Immunological mechanisms underlying protection mediated by RTS,S: a review of the available data. Malar. J. 8: 312.
7. Langhorne, J., F. M. Ndungu, A. M. Sponaas, and K. Marsh. 2008. Immunity to malaria: more questions than answers. Nat. Immunol. 9: 725-732. (Pubitemid 351859155)
8. Fletcher, H. A. 2007. Correlates of immune protection from tuberculosis. Curr. Mol. Med. 7: 319-325. (Pubitemid 46767789)
9. Berenzon, D., R. J. Schwenk, L. Letellier, M. Guebre-Xabier, J. Williams, and U. Krzych. 2003. Protracted protection to Plasmodium berghei malaria is linked to functionally and phenotypically heterogeneous liver memory CD8+ T cells. J. Immunol. 171: 2024-2034. (Pubitemid 36969799)
10. Sallusto, F., A. Lanzavecchia, K. Araki, and R. Ahmed. 2010. From vaccines to memory and back. Immunity 33: 451-463.
11. Clyde, D. F. 1975. Immunization of man against falciparum and vivax malaria by use of attenuated sporozoites. Am. J. Trop. Med. Hyg. 24: 397-401.
12. Nussenzweig, R. S., J. Vanderberg, H. Most, and C. Orton. 1967. Protective immunity produced by the injection of x-irradiated sporozoites of Plasmodium berghei. Nature 216: 160-162.
13. Belnoue, E., F. T. Costa, T. Frankenberg, A. M. Vigário, T. Voza, N. Leroy, M. M. Rodrigues, I. Landau, G. Snounou, and L. Rénia. 2004. Protective T cell immunity against malaria liver stage after vaccination with live sporozoites under chloroquine treatment. J. Immunol. 172: 2487-2495. (Pubitemid 38182399)
14. Roestenberg, M., M. McCall, J. Hopman, J. Wiersma, A. J. Luty, G. J. van Gemert, M. van de Vegte-Bolmer, B. van Schaijk, K. Teelen, T. Arens, et al. 2009. Protection against a malaria challenge by sporozoite inoculation. N. Engl. J. Med. 361: 468-477.
15. Cockburn, I. A., Y. C. Chen, M. G. Overstreet, J. R. Lees, N. van Rooijen, D. L. Farber, and F. Zavala. 2010. Prolonged antigen presentation is required for optimal CD8+ T cell responses against malaria liver stage parasites. PLoS Pathog. 6: e1000877.
16. Reyes-Sandoval, A., T. Berthoud, N. Alder, L. Siani, S. C. Gilbert, A. Nicosia, S. Colloca, R. Cortese, and A. V. Hill. 2010. Prime-boost immunization with adenoviral and modified vaccinia virus Ankara vectors enhances the durability and polyfunctionality of protective malaria CD8+ T-cell responses. Infect. Immun. 78: 145-153.
17. Reyes-Sandoval, A., S. Sridhar, T. Berthoud, A. C. Moore, J. T. Harty, S. C. Gilbert, G. Gao, H. C. Ertl, J. C. Wilson, and A. V. Hill. 2008. Single-dose immunogenicity and protective efficacy of simian adenoviral vectors against Plasmodium berghei. Eur. J. Immunol. 38: 732-741.
18. Tatsis, N., J. C. Fitzgerald, A. Reyes-Sandoval, K. C. Harris-McCoy, S. E. Hensley, D. Zhou, S. W. Lin, A. Bian, Z. Q. Xiang, A. Iparraguirre, et al. 2007. Adenoviral vectors persist in vivo and maintain activated CD8+ T cells: implications for their use as vaccines. Blood 110: 1916-1923. (Pubitemid 47443905)
19. Geiben-Lynn, R., J. R. Greenland, K. Frimpong-Boateng, and N. L. Letvin. 2008. Kinetics of recombinant adenovirus type 5, vaccinia virus, modified vaccinia ankara virus, and DNA antigen expression in vivo and the induction of memory T-lymphocyte responses. Clin. Vaccine Immunol. 15: 691-696. (Pubitemid 351967048)
20. Bachmann, M. F., P. Wolint, K. Schwarz, P. Jäger, and A. Oxenius. 2005. Functional properties and lineage relationship of CD8+ T cell subsets identified by expression of IL-7 receptor alpha and CD62L. J. Immunol. 175: 4686-4696. (Pubitemid 41362010)
21. Gilbert, S. C., M. Plebanski, S. J. Harris, C. E. Allsopp, R. Thomas, G. T. Layton, and A. V. Hill. 1997. A protein particle vaccine containing multiple malaria epitopes. Nat. Biotechnol. 15: 1280-1284. (Pubitemid 27465140)
22. McConkey, S. J., W. H. Reece, V. S. Moorthy, D. Webster, S. Dunachie, G. Butcher, J. M. Vuola, T. J. Blanchard, P. Gothard, K. Watkins, et al. 2003. Enhanced T-cell immunogenicity of plasmid DNA vaccines boosted by recombinant modified vaccinia virus Ankara in humans. Nat. Med. 9: 729-735. (Pubitemid 36749222)
23. Schneider, J., S. C. Gilbert, T. J. Blanchard, T. Hanke, K. J. Robson, C. M. Hannan, M. Becker, R. Sinden, G. L. Smith, and A. V. Hill. 1998. Enhanced immunogenicity for CD8+ T cell induction and complete protective efficacy of malaria DNA vaccination by boosting with modified vaccinia virus Ankara. Nat. Med. 4: 397-402. (Pubitemid 28212753)
24. Roy, S., G. Gao, Y. Lu, X. Zhou, M. Lock, R. Calcedo, and J. M. Wilson. 2004. Characterization of a family of chimpanzee adenoviruses and development of molecular clones for gene transfer vectors. Hum. Gene Ther. 15: 519-530. (Pubitemid 38639622)
25. Janse, C. J., B. Franke-Fayard, G. R. Mair, J. Ramesar, C. Thiel, S. Engelmann, K. Matuschewski, G. J. van Gemert, R. W. Sauerwein, and A. P. Waters. 2006. High efficiency transfection of Plasmodium berghei facilitates novel selection procedures. Mol. Biochem. Parasitol. 145: 60-70. (Pubitemid 41691855)
26. Ploemen, I. H., M. Prudêncio, B. G. Douradinha, J. Ramesar, J. Fonager, G. J. van Gemert, A. J. Luty, C. C. Hermsen, R. W. Sauerwein, F. G. Baptista, et al. 2009. Visualisation and quantitative analysis of the rodent malaria liver stage by real time imaging. PLoS ONE 4: e7881.
27. Bejon, P., L. Andrews, R. F. Andersen, S. Dunachie, D. Webster, M. Walther, S. C. Gilbert, T. Peto, and A. V. Hill. 2005. Calculation of liver-to-blood inocula, parasite growth rates, and preerythrocytic vaccine efficacy, from serial quantitative polymerase chain reaction studies of volunteers challenged with malaria sporozoites. J. Infect. Dis. 191: 619-626. (Pubitemid 40216679)
28. Sallusto, F., D. Lenig, R. Förster, M. Lipp, and A. Lanzavecchia. 1999. Two subsets of memory T lymphocytes with distinct homing potentials and effector functions. Nature 401: 708-712.
29. Wherry, E. J., V. Teichgräber, T. C. Becker, D. Masopust, S. M. Kaech, R. Antia, U. H. von Andrian, and R. Ahmed. 2003. Lineage relationship and protective immunity of memory CD8 T cell subsets. Nat. Immunol. 4: 225-234. (Pubitemid 36322131)
30. Witney, A. A., D. L. Doolan, R. M. Anthony, W. R. Weiss, S. L. Hoffman, and D. J. Carucci. 2001. Determining liver stage parasite burden by real time quantitative PCR as a method for evaluating pre-erythrocytic malaria vaccine efficacy. Mol. Biochem. Parasitol. 118: 233-245. (Pubitemid 34001686)
31. Aly, A. S., A. M. Vaughan, and S. H. Kappe. 2009. Malaria parasite development in the mosquito and infection of the mammalian host. Annu. Rev. Microbiol. 63: 195-221.
32. Overstreet, M. G., I. A. Cockburn, Y. C. Chen, and F. Zavala. 2008. Protective CD8 T cells against Plasmodium liver stages: immunobiology of an 'unnatural'immune response. Immunol. Rev. 225: 272-283.
33. Dunachie, S. J., M. Walther, J. E. Epstein, S. Keating, T. Berthoud, L. Andrews, R. F. Andersen, P. Bejon, N. Goonetilleke, I. Poulton, et al. 2006. A DNA prime-modified vaccinia virus ankara boost vaccine encoding thrombospondin-related adhesion protein but not circumsporozoite protein partially protects healthy malaria-naive adults against Plasmodium falciparum sporozoite challenge. Infect. Immun. 74: 5933-5942. (Pubitemid 44484581)
34. Bachmann, M. F., P. Wolint, K. Schwarz, and A. Oxenius. 2005. Recall proliferation potential of memory CD8+ T cells and antiviral protection. J. Immunol. 175: 4677-4685. (Pubitemid 41362009)
35. Schmidt, N. W., N. S. Butler, V. P. Badovinac, and J. T. Harty. 2010. Extreme CD8 T cell requirements for anti-malarial liver-stage immunity following immunization with radiation attenuated sporozoites. PLoS Pathog. 6: e1000998.