-
1
-
-
0033600176
-
Characterization of five human cDNAs with homology to the yeast SIR2 gene: Sir2-like proteins (sirtuins) metabolize NAD and may have protein ADP-ribosyltransferase activity
-
Frye RA. Characterization of five human cDNAs with homology to the yeast SIR2 gene: Sir2-like proteins (sirtuins) metabolize NAD and may have protein ADP-ribosyltransferase activity. Biochem Biophys Res Commun 1999; 260: 273-279.
-
(1999)
Biochem Biophys Res Commun
, vol.260
, pp. 273-279
-
-
Frye, R.A.1
-
2
-
-
79952806932
-
Sirtuins at a glance
-
Nakagawa T and Guarente L. Sirtuins at a glance. J Cell Sci 2011; 124: 833-838.
-
(2011)
J Cell Sci
, vol.124
, pp. 833-838
-
-
Nakagawa, T.1
Guarente, L.2
-
5
-
-
67949102053
-
Recent progress in the biology and physiology of sirtuins
-
Finkel T, Deng CX and Mostoslavsky R. Recent progress in the biology and physiology of sirtuins. Nature 2009; 460: 587-591.
-
(2009)
Nature
, vol.460
, pp. 587-591
-
-
Finkel, T.1
Deng, C.X.2
Mostoslavsky, R.3
-
6
-
-
84870999850
-
The NAD-dependent deacetylase SIRT2 is required for programmed necrosis
-
Narayan N, Lee IH, Borenstein R, Sun J, Wong R, Tong G, Fergusson MM, Liu J, Rovira II, Cheng HL, Wang G, Gucek M, Lombard D, Alt FW, Sack MN, Murphy E, Cao L and Finkel T. The NAD-dependent deacetylase SIRT2 is required for programmed necrosis. Nature 2012; 492: 199-204.
-
(2012)
Nature
, vol.492
, pp. 199-204
-
-
Narayan, N.1
Lee, I.H.2
Borenstein, R.3
Sun, J.4
Wong, R.5
Tong, G.6
Fergusson, M.M.7
Liu, J.8
Rovira, I.I.9
Cheng, H.L.10
Wang, G.11
Gucek, M.12
Lombard, D.13
Alt, F.W.14
Sack, M.N.15
Murphy, E.16
Cao, L.17
Finkel, T.18
-
7
-
-
34547599329
-
Sirtuin 2 inhibitors rescue α-synuclein-mediated toxicity in models of Parkinson’s disease
-
Outeiro TF, Kontopoulos E, Altmann SM, Kufareva I, Strathearn KE, Amore AM, Volk CB, Maxwell MM, Rochet JC and McLean PJ. Sirtuin 2 inhibitors rescue α-synuclein-mediated toxicity in models of Parkinson’s disease. Science 2007; 317: 516-519.
-
(2007)
Science
, vol.317
, pp. 516-519
-
-
Outeiro, T.F.1
Kontopoulos, E.2
Altmann, S.M.3
Kufareva, I.4
Strathearn, K.E.5
Amore, A.M.6
Volk, C.B.7
Maxwell, M.M.8
Rochet, J.C.9
McLean, P.J.10
-
8
-
-
77952413052
-
SIRT2 inhibition achieves neuroprotection by decreasing sterol biosynthesis
-
Luthi-Carter R, Taylor DM, Pallos J, Lambert E, Amore A, Parker A, Moffitt H, Smith DL, Runne H and Gokce O. SIRT2 inhibition achieves neuroprotection by decreasing sterol biosynthesis. Proc Nati Acad Sci U S A 2010; 107: 7927-7932.
-
(2010)
Proc Nati Acad Sci U S A
, vol.107
, pp. 7927-7932
-
-
Luthi-Carter, R.1
Taylor, D.M.2
Pallos, J.3
Lambert, E.4
Amore, A.5
Parker, A.6
Moffitt, H.7
Smith, D.L.8
Runne, H.9
Gokce, O.10
-
9
-
-
84855769254
-
SIRT2 activity is required for the survival of C6 glioma cells
-
He X, Nie H, Hong Y, Sheng C, Xia W and Ying W. SIRT2 activity is required for the survival of C6 glioma cells. Biochem Biophys Res Commun 2012; 417: 468-472.
-
(2012)
Biochem Biophys Res Commun
, vol.417
, pp. 468-472
-
-
He, X.1
Nie, H.2
Hong, Y.3
Sheng, C.4
Xia, W.5
Ying, W.6
-
10
-
-
78650638268
-
SIRT2 down-regulation in HeLa can induce p53 accumulation via p38 MAPK activation-dependent p300 decrease, eventually leading to apoptosis
-
Li Y, Matsumori H, Nakayama Y, Osaki M, Kojima H, Kurimasa A, Ito H, Mori S, Katoh M and Oshimura M. SIRT2 down-regulation in HeLa can induce p53 accumulation via p38 MAPK activation-dependent p300 decrease, eventually leading to apoptosis. Genes Cells 2011; 16: 34-45.
-
(2011)
Genes Cells
, vol.16
, pp. 34-45
-
-
Li, Y.1
Matsumori, H.2
Nakayama, Y.3
Osaki, M.4
Kojima, H.5
Kurimasa, A.6
Ito, H.7
Mori, S.8
Katoh, M.9
Oshimura, M.10
-
11
-
-
0037405043
-
Role for human SIRT2 NAD-dependent deacetylase activity in control of mitotic exit in the cell cycle
-
Dryden SC, Nahhas FA, Nowak JE, Goustin AS and Tainsky MA. Role for human SIRT2 NAD-dependent deacetylase activity in control of mitotic exit in the cell cycle. Mol Cell Biol 2003; 23: 3173-3185.
-
(2003)
Mol Cell Biol
, vol.23
, pp. 3173-3185
-
-
Dryden, S.C.1
Nahhas, F.A.2
Nowak, J.E.3
Goustin, A.S.4
Tainsky, M.A.5
-
12
-
-
3142548829
-
Human histone deacetylase SIRT2 interacts with the homeobox transcription factor HOXA10
-
Bae NS, Swanson MJ, Vassilev A and Howard BH. Human histone deacetylase SIRT2 interacts with the homeobox transcription factor HOXA10. J Biochem 2004; 135: 695-700.
-
(2004)
J Biochem
, vol.135
, pp. 695-700
-
-
Bae, N.S.1
Swanson, M.J.2
Vassilev, A.3
Howard, B.H.4
-
13
-
-
33847053144
-
SIRT2, a tubulin deacetylase, acts to block the entry to chromosome condensation in response to mitotic stress
-
Inoue T, Hiratsuka M, Osaki M, Yamada H, Kishimoto I, Yamaguchi S, Nakano S, Katoh M, Ito H and Oshimura M. SIRT2, a tubulin deacetylase, acts to block the entry to chromosome condensation in response to mitotic stress. Oncogene 2007; 26: 945-957.
-
(2007)
Oncogene
, vol.26
, pp. 945-957
-
-
Inoue, T.1
Hiratsuka, M.2
Osaki, M.3
Yamada, H.4
Kishimoto, I.5
Yamaguchi, S.6
Nakano, S.7
Katoh, M.8
Ito, H.9
Oshimura, M.10
-
14
-
-
40849113090
-
The regulation of SIRT2 function by cyclin-dependent kinases affects cell motility
-
Pandithage R, Lilischkis R, Harting K, Wolf A, Jedamzik B, Lüscher-Firzlaff J, Vervoorts J, Lasonder E, Kremmer E and Knöll B. The regulation of SIRT2 function by cyclin-dependent kinases affects cell motility. J Cell biol 2008; 180: 915-929.
-
(2008)
J Cell biol
, vol.180
, pp. 915-929
-
-
Pandithage, R.1
Lilischkis, R.2
Harting, K.3
Wolf, A.4
Jedamzik, B.5
Lüscher-Firzlaff, J.6
Vervoorts, J.7
Lasonder, E.8
Kremmer, E.9
Knöll, B.10
-
16
-
-
19744380563
-
Resting microglial cells are highly dynamic surveillants of brain parenchyma in vivo
-
Nimmerjahn A, Kirchhoff F and Helmchen F. Resting microglial cells are highly dynamic surveillants of brain parenchyma in vivo. Science 2005; 308: 1314-1318.
-
(2005)
Science
, vol.308
, pp. 1314-1318
-
-
Nimmerjahn, A.1
Kirchhoff, F.2
Helmchen, F.3
-
18
-
-
84880089425
-
Microglial physiopathology: How to explain the dual role of microglia after acute neural disorders?
-
Gomes-Leal W. Microglial physiopathology: how to explain the dual role of microglia after acute neural disorders? Brain Behav 2012; 2: 345-356.
-
(2012)
Brain Behav
, vol.2
, pp. 345-356
-
-
Gomes-Leal, W.1
-
19
-
-
84885173084
-
The NAD-dependent deacetylase sirtuin 2 is a suppressor of microglial activation and brain inflammation
-
Pais TF, Szego EM, Marques O, Miller-Fleming L, Antas P, Guerreiro P, de Oliveira RM, Kasapoglu B and Outeiro TF. The NAD-dependent deacetylase sirtuin 2 is a suppressor of microglial activation and brain inflammation. EMBO J 2013; 32: 2603-16.
-
(2013)
EMBO J
, vol.32
, pp. 2603-2616
-
-
Pais, T.F.1
Szego, E.M.2
Marques, O.3
Miller-Fleming, L.4
Antas, P.5
Guerreiro, P.6
De Oliveira, R.M.7
Kasapoglu, B.8
Outeiro, T.F.9
-
20
-
-
77956915352
-
Liu B and Zhu Z. miR-126 functions as a tumour suppressor in human gastric cancer
-
Feng R, Chen X, Yu Y, Su L, Yu B, Li J, Cai Q, Yan M, Liu B and Zhu Z. miR-126 functions as a tumour suppressor in human gastric cancer. Cancer Lett 2010; 298: 50-63.
-
(2010)
Cancer Lett
, vol.298
, pp. 50-63
-
-
Feng, R.1
Chen, X.2
Yu, Y.3
Su, L.4
Yu, B.5
Li, J.6
Cai, Q.7
Yan, M.8
-
21
-
-
2442624618
-
Poly(ADP-ribose) polymerase-1-mediated cell death in astrocytes requires NAD+ depletion and mitochondrial permeability transition
-
Alano CC, Ying W and Swanson RA. Poly(ADP-ribose) polymerase-1-mediated cell death in astrocytes requires NAD+ depletion and mitochondrial permeability transition. J Biol Chem 2004; 279: 18895-18902.
-
(2004)
J Biol Chem
, vol.279
, pp. 18895-18902
-
-
Alano, C.C.1
Ying, W.2
Swanson, R.A.3
-
22
-
-
84878396726
-
Poly(ADP-ribose) polymerase mediates both cell death and ATP decreases in SIRT2 inhibitor AGK2-treated microglial BV2 cells
-
Li Y, Nie H, Wu D, Zhang J, Wei X and Ying W. Poly(ADP-ribose) polymerase mediates both cell death and ATP decreases in SIRT2 inhibitor AGK2-treated microglial BV2 cells. Neurosci Lett 2013; 544: 36-40.
-
(2013)
Neurosci Lett
, vol.544
, pp. 36-40
-
-
Li, Y.1
Nie, H.2
Wu, D.3
Zhang, J.4
Wei, X.5
Ying, W.6
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