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Volumn 8, Issue SEP, 2014, Pages

Fluxes of lactate into, from, and among gap junction-coupled astrocytes and their interaction with noradrenaline

Author keywords

Acetate; Astrocyte; Lactate; Locus coeruleus; Memory; Monocarboxylic acid transporter; Neuron

Indexed keywords

CYCLIC AMP; GLUCOSE; GLUTAMIC ACID; LACTIC ACID; MEDIUM CHAIN TRIACYLGLYCEROL; MONOCARBOXYLATE TRANSPORTER; NORADRENALIN;

EID: 84907951741     PISSN: 16624548     EISSN: 1662453X     Source Type: Journal    
DOI: 10.3389/fnins.2014.00261     Document Type: Review
Times cited : (50)

References (70)
  • 1
    • 0028854370 scopus 로고
    • Labeling of metabolic pools by [6-14C]glucose during K(+)-induced stimulation of glucose utilization in rat brain
    • Adachi, K., Cruz, N. F., Sokoloff, L., and Dienel, G. A. (1995). Labeling of metabolic pools by [6-14C]glucose during K(+)-induced stimulation of glucose utilization in rat brain. J. Cereb. Blood Flow Metab. 15, 97-110. doi: 10.1038/jcbfm.1995.11
    • (1995) J. Cereb. Blood Flow Metab , vol.15 , pp. 97-110
    • Adachi, K.1    Cruz, N.F.2    Sokoloff, L.3    Dienel, G.A.4
  • 2
    • 0347689714 scopus 로고
    • Control of glutamate oxidation in brain and liver mitochondrial systems
    • Balazs, R. (1965). Control of glutamate oxidation in brain and liver mitochondrial systems. Biochem. J. 95, 497-508.
    • (1965) Biochem. J. , vol.95 , pp. 497-508
    • Balazs, R.1
  • 3
    • 73949138881 scopus 로고    scopus 로고
    • Trafficking of glucose, lactate, and amyloid-beta from the inferior colliculus through perivascular routes
    • Ball, K. K., Cruz, N. F., Mrak, R. E., and Dienel, G. A. (2010). Trafficking of glucose, lactate, and amyloid-beta from the inferior colliculus through perivascular routes. J. Cereb. Blood Flow Metab. 30, 162-176. doi: 10.1038/jcbfm.2009.206
    • (2010) J. Cereb. Blood Flow Metab , vol.30 , pp. 162-176
    • Ball, K.K.1    Cruz, N.F.2    Mrak, R.E.3    Dienel, G.A.4
  • 4
    • 35448976605 scopus 로고    scopus 로고
    • Astrocytic connexin distributions and rapid, extensive dye transfer via gap junctions in the inferior colliculus: implications for [(14)C]glucose metabolite trafficking
    • Ball, K. K., Gandhi, G. K., Thrash, J., Cruz, N. F., and Dienel, G. A. (2007). Astrocytic connexin distributions and rapid, extensive dye transfer via gap junctions in the inferior colliculus: implications for [(14)C]glucose metabolite trafficking. J. Neurosci. Res. 85, 3267-3283. doi: 10.1002/jnr.21376
    • (2007) J. Neurosci. Res , vol.85 , pp. 3267-3283
    • Ball, K.K.1    Gandhi, G.K.2    Thrash, J.3    Cruz, N.F.4    Dienel, G.A.5
  • 5
    • 52049121361 scopus 로고    scopus 로고
    • Locus coeruleus alpha-adrenergic-mediated activation of cortical astrocytes in vivo
    • Bekar, L. K., He, W., and Nedergaard, M. (2008). Locus coeruleus alpha-adrenergic-mediated activation of cortical astrocytes in vivo. Cereb. Cortex 18, 2789-2795. doi: 10.1093/cercor/bhn040
    • (2008) Cereb. Cortex , vol.18 , pp. 2789-2795
    • Bekar, L.K.1    He, W.2    Nedergaard, M.3
  • 6
    • 79951686964 scopus 로고    scopus 로고
    • The sirtuin pathway in ageing and Alzheimer disease: mechanistic and therapeutic considerations
    • Bonda, D. J., Lee, H. G., Camins, A., Pallas, M., Casadesus, G., Smith, M. A., et al. (2011). The sirtuin pathway in ageing and Alzheimer disease: mechanistic and therapeutic considerations. Lancet Neurol. 10, 275-279. doi: 10.1016/s1474-4422(11)70013-8
    • (2011) Lancet Neurol , vol.10 , pp. 275-279
    • Bonda, D.J.1    Lee, H.G.2    Camins, A.3    Pallas, M.4    Casadesus, G.5    Smith, M.A.6
  • 7
    • 0141863313 scopus 로고    scopus 로고
    • Regulation and modulation of pH in the brain
    • Chesler, M. (2003). Regulation and modulation of pH in the brain. Physiol. Rev. 83, 1183-1221. doi: 10.1152/physrev.00010.2003
    • (2003) Physiol. Rev , vol.83 , pp. 1183-1221
    • Chesler, M.1
  • 8
    • 0033503070 scopus 로고    scopus 로고
    • Rapid efflux of lactate from cerebral cortex during K+-induced spreading cortical depression
    • Cruz, N. F., Adachi, K., and Dienel, G. A. (1999). Rapid efflux of lactate from cerebral cortex during K+-induced spreading cortical depression. J. Cereb. Blood Flow Metab. 19, 380-392. doi: 10.1097/00004647-199904000-00004
    • (1999) J. Cereb. Blood Flow Metab , vol.19 , pp. 380-392
    • Cruz, N.F.1    Adachi, K.2    Dienel, G.A.3
  • 9
    • 0842322960 scopus 로고    scopus 로고
    • A reduced cerebral metabolic ratio in exercise reflects metabolism and not accumulation of lactate within the human brain
    • Dalsgaard, M. K., Quistorff, B., Danielsen, E. R., Selmer, C., Vogelsang, T., and Secher, N. H. (2004). A reduced cerebral metabolic ratio in exercise reflects metabolism and not accumulation of lactate within the human brain. J. Physiol. 554, 571-578. doi: 10.1113/jphysiol.2003.055053
    • (2004) J. Physiol , vol.554 , pp. 571-578
    • Dalsgaard, M.K.1    Quistorff, B.2    Danielsen, E.R.3    Selmer, C.4    Vogelsang, T.5    Secher, N.H.6
  • 10
    • 0017641188 scopus 로고
    • Comparative studies on glutamate metabolism in synpatic and non-synaptic rat brain mitochondria
    • Dennis, S. C., Lai, J. C., and Clark, J. B. (1977). Comparative studies on glutamate metabolism in synpatic and non-synaptic rat brain mitochondria. Biochem. J. 164, 727-736.
    • (1977) Biochem. J. , vol.164 , pp. 727-736
    • Dennis, S.C.1    Lai, J.C.2    Clark, J.B.3
  • 11
    • 84866697175 scopus 로고    scopus 로고
    • Fueling and imaging brain activation
    • Dienel, G. A. (2012). Fueling and imaging brain activation. ASN Neuro 4:e00093. doi: 10.1042/AN20120021
    • (2012) ASN Neuro , vol.4 , pp. e00093
    • Dienel, G.A.1
  • 12
    • 0035577699 scopus 로고    scopus 로고
    • Glucose and lactate metabolism during brain activation
    • Dienel, G. A., and Hertz, L. (2001). Glucose and lactate metabolism during brain activation. J. Neurosci. Res. 66, 824-838. doi: 10.1002/jnr.10079
    • (2001) J. Neurosci. Res , vol.66 , pp. 824-838
    • Dienel, G.A.1    Hertz, L.2
  • 13
    • 0029871779 scopus 로고    scopus 로고
    • Evidence that stress activates glial lactate formation in vivo assessed with rat hippocampus lactography
    • Elekes, O., Venema, K., Postema, F., Dringen, R., Hamprecht, B., and Korf, J. (1996). Evidence that stress activates glial lactate formation in vivo assessed with rat hippocampus lactography. Neurosci. Lett. 208, 69-72. doi: 10.1016/0304-3940(96)12553-2
    • (1996) Neurosci. Lett , vol.208 , pp. 69-72
    • Elekes, O.1    Venema, K.2    Postema, F.3    Dringen, R.4    Hamprecht, B.5    Korf, J.6
  • 14
    • 0028079648 scopus 로고
    • Astroglial gap junction communication is increased by treatment with either glutamate or high K+ concentration
    • Enkvist, M. O., and McCarthy, K. D. (1994). Astroglial gap junction communication is increased by treatment with either glutamate or high K+ concentration. J. Neurochem. 62, 489-495. doi: 10.1046/j.1471-4159.1994.62020489.x
    • (1994) J. Neurochem , vol.62 , pp. 489-495
    • Enkvist, M.O.1    McCarthy, K.D.2
  • 15
    • 0041923828 scopus 로고    scopus 로고
    • Differential binding of NAD+ and NADH allows the transcriptional corepressor carboxyl-terminal binding protein to serve as a metabolic sensor
    • Fjeld, C. C., Birdsong, W. T., and Goodman, R. H. (2003). Differential binding of NAD+ and NADH allows the transcriptional corepressor carboxyl-terminal binding protein to serve as a metabolic sensor. Proc. Natl. Acad. Sci. U.S.A. 100, 9202-9207. doi: 10.1073/pnas.1633591100
    • (2003) Proc. Natl. Acad. Sci. U.S.A , vol.100 , pp. 9202-9207
    • Fjeld, C.C.1    Birdsong, W.T.2    Goodman, R.H.3
  • 16
    • 0023780085 scopus 로고
    • Nonoxidative glucose consumption during focal physiologic neural activity
    • Fox, P. T., Raichle, M. E., Mintun, M. A., and Dence, C. (1988). Nonoxidative glucose consumption during focal physiologic neural activity. Science 241, 462-464. doi: 10.1126/science.3260686
    • (1988) Science , vol.241 , pp. 462-464
    • Fox, P.T.1    Raichle, M.E.2    Mintun, M.A.3    Dence, C.4
  • 17
    • 70350396945 scopus 로고    scopus 로고
    • Maintained cerebral metabolic ratio during exercise in patients with beta-adrenergic blockade
    • Gam, C. M., Rasmussen, P., Secher, N. H., Seifert, T., Larsen, F. S., and Nielsen, H. B. (2009). Maintained cerebral metabolic ratio during exercise in patients with beta-adrenergic blockade. Clin. Physiol. Funct. Imaging 29, 420-426. doi: 10.1111/j.1475-097X.2009.00889.x
    • (2009) Clin. Physiol. Funct. Imaging , vol.29 , pp. 420-426
    • Gam, C.M.1    Rasmussen, P.2    Secher, N.H.3    Seifert, T.4    Larsen, F.S.5    Nielsen, H.B.6
  • 18
    • 70349337150 scopus 로고    scopus 로고
    • Astrocytes are poised for lactate trafficking and release from activated brain and for supply of glucose to neurons
    • Gandhi, G. K., Cruz, N. F., Ball, K. K., and Dienel, G. A. (2009). Astrocytes are poised for lactate trafficking and release from activated brain and for supply of glucose to neurons. J. Neurochem. 111, 522-536. doi: 10.1111/j.1471-4159.2009.06333.x
    • (2009) J. Neurochem , vol.111 , pp. 522-536
    • Gandhi, G.K.1    Cruz, N.F.2    Ball, K.K.3    Dienel, G.A.4
  • 19
    • 33750443292 scopus 로고    scopus 로고
    • 2-Deoxy-D-glucose reduces epilepsy progression by NRSF-CtBP-dependent metabolic regulation of chromatin structure
    • Garriga-Canut, M., Schoenike, B., Qazi, R., Bergendahl, K., Daley, T. J., Pfender, R. M., et al. (2006). 2-Deoxy-D-glucose reduces epilepsy progression by NRSF-CtBP-dependent metabolic regulation of chromatin structure. Nat. Neurosci. 9, 1382-1387. doi: 10.1038/nn1791
    • (2006) Nat. Neurosci , vol.9 , pp. 1382-1387
    • Garriga-Canut, M.1    Schoenike, B.2    Qazi, R.3    Bergendahl, K.4    Daley, T.J.5    Pfender, R.M.6
  • 20
    • 0018350614 scopus 로고
    • Regulation of mitochondrial pyruvate carboxylation and gluconeogenesis in rat hepatocytes via an alpha-adrenergic, adenosine 3':5'-monophosphate-independent mechanism
    • Garrison, J. C., and Borland, M. K. (1979). Regulation of mitochondrial pyruvate carboxylation and gluconeogenesis in rat hepatocytes via an alpha-adrenergic, adenosine 3':5'-monophosphate-independent mechanism. J. Biol. chem. 254, 1129-1133.
    • (1979) J. Biol. chem. , vol.254 , pp. 1129-1133
    • Garrison, J.C.1    Borland, M.K.2
  • 21
    • 40949125201 scopus 로고    scopus 로고
    • Inhibition of astrocytic energy metabolism by D-lactate exposure impairs memory
    • Gibbs, M. E., and Hertz, L. (2008). Inhibition of astrocytic energy metabolism by D-lactate exposure impairs memory. Neurochem. Int. 52, 1012-1018. doi: 10.1016/j.neuint.2007.10.014
    • (2008) Neurochem. Int , vol.52 , pp. 1012-1018
    • Gibbs, M.E.1    Hertz, L.2
  • 22
    • 35449001544 scopus 로고    scopus 로고
    • Glycogen is a preferred glutamate precursor during learning in 1-day-old chick: biochemical and behavioral evidence
    • Gibbs, M. E., Lloyd, H. G., Santa, T., and Hertz, L. (2007). Glycogen is a preferred glutamate precursor during learning in 1-day-old chick: biochemical and behavioral evidence. J. Neurosci. Res. 85, 3326-3333. doi: 10.1002/jnr.21307
    • (2007) J. Neurosci. Res , vol.85 , pp. 3326-3333
    • Gibbs, M.E.1    Lloyd, H.G.2    Santa, T.3    Hertz, L.4
  • 23
    • 57649118670 scopus 로고    scopus 로고
    • Brain metabolism dictates the polarity of astrocyte control over arterioles
    • Gordon, G. R., Choi, H. B., Rungta, R. L., Ellis-Davies, G. C., and Macvicar, B. A. (2008). Brain metabolism dictates the polarity of astrocyte control over arterioles. Nature 456, 745-749. doi: 10.1038/nature07525
    • (2008) Nature , vol.456 , pp. 745-749
    • Gordon, G.R.1    Choi, H.B.2    Rungta, R.L.3    Ellis-Davies, G.C.4    Macvicar, B.A.5
  • 24
    • 77149172855 scopus 로고    scopus 로고
    • SIRT2-mediated protein deacetylation: an emerging key regulator in brain physiology and pathology
    • Harting, K., and Knoll, B. (2010). SIRT2-mediated protein deacetylation: an emerging key regulator in brain physiology and pathology. Eur. J. Cell. Biol. 89, 262-269. doi: 10.1016/j.ejcb.2009.11.006
    • (2010) Eur. J. Cell. Biol , vol.89 , pp. 262-269
    • Harting, K.1    Knoll, B.2
  • 25
    • 33644856900 scopus 로고    scopus 로고
    • Dilation of retinal arterioles in response to lactate: role of nitric oxide, guanylyl cyclase, and ATP-sensitive potassium channels
    • Hein, T. W., Xu, W., and Kuo, L. (2006). Dilation of retinal arterioles in response to lactate: role of nitric oxide, guanylyl cyclase, and ATP-sensitive potassium channels. Invest. Ophthalmol. Vis. Sci. 47, 693-699. doi: 10.1167/iovs.05-1224
    • (2006) Invest. Ophthalmol. Vis. Sci , vol.47 , pp. 693-699
    • Hein, T.W.1    Xu, W.2    Kuo, L.3
  • 26
    • 78650917864 scopus 로고    scopus 로고
    • Brain glutamine synthesis requires neuronal aspartate: a commentary
    • Hertz, L. (2011). Brain glutamine synthesis requires neuronal aspartate: a commentary. J. Cereb. Blood Flow Metab. 31, 384-387. doi: 10.1038/jcbfm.2010.199
    • (2011) J. Cereb. Blood Flow Metab , vol.31 , pp. 384-387
    • Hertz, L.1
  • 27
    • 12244295472 scopus 로고    scopus 로고
    • Lactate transport and transporters: general principles and functional roles in brain cells
    • Hertz, L., and Dienel, G. A. (2005). Lactate transport and transporters: general principles and functional roles in brain cells. J. Neurosci. Res. 79, 11-18. doi: 10.1002/jnr.20294
    • (2005) J. Neurosci. Res , vol.79 , pp. 11-18
    • Hertz, L.1    Dienel, G.A.2
  • 28
    • 84901056651 scopus 로고    scopus 로고
    • Astrocytic-neuronal-astrocytic pathway selection for formation and degradation of glutamate/GABA
    • (eds.). e-Book Frontiers in Endocrinology.
    • Hertz, L., and Rodrigues, T. B. (eds.). (2014). Astrocytic-neuronal-astrocytic pathway selection for formation and degradation of glutamate/GABA. e-Book Frontiers in Endocrinology.
    • (2014)
    • Hertz, L.1    Rodrigues, T.B.2
  • 29
    • 0025875193 scopus 로고
    • Muscle lactate transport studied in sarcolemmal giant vesicles
    • Juel, C. (1991). Muscle lactate transport studied in sarcolemmal giant vesicles. Biochim. Biophys. Acta 1065, 15-20. doi: 10.1016/0005-2736(91)90004-R
    • (1991) Biochim. Biophys. Acta , vol.1065 , pp. 15-20
    • Juel, C.1
  • 30
    • 0344086180 scopus 로고    scopus 로고
    • Lactate transport in skeletal muscle-role and regulation of the monocarboxylate transporter
    • Juel, C., and Halestrap, A. P. (1999). Lactate transport in skeletal muscle-role and regulation of the monocarboxylate transporter. J. Physiol. 517 (Pt 3), 633-642. doi: 10.1111/j.1469-7793.1999.0633s.x
    • (1999) J. Physiol. , vol.517 , pp. 633-642
    • Juel, C.1    Halestrap, A.P.2
  • 31
    • 0028285096 scopus 로고
    • Kinetics of lactate transport in sarcolemmal giant vesicles obtained from human skeletal muscle
    • Juel, C., Kristiansen, S., Pilegaard, H., Wojtaszewski, J., and Richter, E. A. (1994). Kinetics of lactate transport in sarcolemmal giant vesicles obtained from human skeletal muscle. J. Appl. Physiol. 76, 1031-1036.
    • (1994) J. Appl. Physiol. , vol.76 , pp. 1031-1036
    • Juel, C.1    Kristiansen, S.2    Pilegaard, H.3    Wojtaszewski, J.4    Richter, E.A.5
  • 32
    • 0025012269 scopus 로고
    • Lactography as an approach to monitor glucose metabolism on-line in brain and muscle
    • Korf, J., and De Boer, J. (1990). Lactography as an approach to monitor glucose metabolism on-line in brain and muscle. Int. J. Biochem. 22, 1371-1378. doi: 10.1016/0020-711X(90)90225-R
    • (1990) Int. J. Biochem , vol.22 , pp. 1371-1378
    • Korf, J.1    De Boer, J.2
  • 33
    • 0036810314 scopus 로고    scopus 로고
    • Transcription corepressor CtBP is an NAD(+)-regulated dehydrogenase
    • Kumar, V., Carlson, J. E., Ohgi, K. A., Edwards, T. A., Rose, D. W., Escalante, C. R., et al. (2002). Transcription corepressor CtBP is an NAD(+)-regulated dehydrogenase. Mol. Cell 10, 857-869. doi: 10.1016/S1097-2765(02)00650-0
    • (2002) Mol. Cell , vol.10 , pp. 857-869
    • Kumar, V.1    Carlson, J.E.2    Ohgi, K.A.3    Edwards, T.A.4    Rose, D.W.5    Escalante, C.R.6
  • 34
    • 0023864449 scopus 로고
    • Effects of lactic acid infusions and pH on cerebral blood flow and metabolism
    • Laptook, A. R., Peterson, J., and Porter, A. M. (1988). Effects of lactic acid infusions and pH on cerebral blood flow and metabolism. J. Cereb. Blood Flow Metab. 8, 193-200. doi: 10.1038/jcbfm.1988.49
    • (1988) J. Cereb. Blood Flow Metab , vol.8 , pp. 193-200
    • Laptook, A.R.1    Peterson, J.2    Porter, A.M.3
  • 35
    • 84929046195 scopus 로고    scopus 로고
    • Lactate receptor sites link neurotransmission, neurovascular coupling, and brain energy metabolism
    • Lauritzen, K. H., Morland, C., Puchades, M., Holm-Hansen, S., Hagelin, E. M., Lauritzen, F., et al. (2013). Lactate receptor sites link neurotransmission, neurovascular coupling, and brain energy metabolism. Cereb. Cortex. 24, 2784-2795. doi: 10.1093/cercor/bht13
    • (2013) Cereb. Cortex , vol.24 , pp. 2784-2795
    • Lauritzen, K.H.1    Morland, C.2    Puchades, M.3    Holm-Hansen, S.4    Hagelin, E.M.5    Lauritzen, F.6
  • 36
    • 33645735689 scopus 로고    scopus 로고
    • A novel mechanism for regulation of retinal blood flow by lactate: gap junctions, hypoxia, and pericytes
    • Lombard, J. H. (2006). A novel mechanism for regulation of retinal blood flow by lactate: gap junctions, hypoxia, and pericytes. Am. J. Physiol. Heart Circ. Physiol. 290, H921-H922. doi: 10.1152/ajpheart.01268.2005
    • (2006) Am. J. Physiol. Heart Circ. Physiol , vol.290 , pp. H921-H922
    • Lombard, J.H.1
  • 37
    • 0033495941 scopus 로고    scopus 로고
    • Cerebral oxygen/glucose ratio is low during sensory stimulation and rises above normal during recovery: excess glucose consumption during stimulation is not accounted for by lactate efflux from or accumulation in brain tissue
    • Madsen, P. L., Cruz, N. F., Sokoloff, L., and Dienel, G. A. (1999). Cerebral oxygen/glucose ratio is low during sensory stimulation and rises above normal during recovery: excess glucose consumption during stimulation is not accounted for by lactate efflux from or accumulation in brain tissue. J. Cereb. Blood Flow Metab. 19, 393-400. doi: 10.1097/00004647-199904000-00005
    • (1999) J. Cereb. Blood Flow Metab , vol.19 , pp. 393-400
    • Madsen, P.L.1    Cruz, N.F.2    Sokoloff, L.3    Dienel, G.A.4
  • 38
    • 0028904071 scopus 로고
    • Persistent resetting of the cerebral oxygen/glucose uptake ratio by brain activation: evidence obtained with the Kety-Schmidt technique
    • Madsen, P. L., Hasselbalch, S. G., Hagemann, L. P., Olsen, K. S., Bulow, J., Holm, S., et al. (1995). Persistent resetting of the cerebral oxygen/glucose uptake ratio by brain activation: evidence obtained with the Kety-Schmidt technique. J. Cereb. Blood Flow Metab. 15, 485-491. doi: 10.1038/jcbfm.1995.60
    • (1995) J. Cereb. Blood Flow Metab , vol.15 , pp. 485-491
    • Madsen, P.L.1    Hasselbalch, S.G.2    Hagemann, L.P.3    Olsen, K.S.4    Bulow, J.5    Holm, S.6
  • 39
    • 84871427156 scopus 로고    scopus 로고
    • Metabolic Pathways and Activity-Dependent Modulation of Glutamate Concentration in the Human Brain
    • Mangia, S., Giove, F., and Dinuzzo, M. (2012). Metabolic Pathways and Activity-Dependent Modulation of Glutamate Concentration in the Human Brain. Neurochem. Res. 37, 2554-2561. doi: 10.1007/s11064-012-0848-4
    • (2012) Neurochem. Res , vol.37 , pp. 2554-2561
    • Mangia, S.1    Giove, F.2    Dinuzzo, M.3
  • 40
    • 64349101696 scopus 로고    scopus 로고
    • The in vivo neuron-to-astrocyte lactate shuttle in human brain: evidence from modeling of measured lactate levels during visual stimulation
    • Mangia, S., Simpson, I. A., Vannucci, S. J., and Carruthers, A. (2009). The in vivo neuron-to-astrocyte lactate shuttle in human brain: evidence from modeling of measured lactate levels during visual stimulation. J. Neurochem. 109 (Suppl. 1), 55-62. doi: 10.1111/j.1471-4159.2009.06003.x
    • (2009) J. Neurochem. , vol.109 , pp. 55-62
    • Mangia, S.1    Simpson, I.A.2    Vannucci, S.J.3    Carruthers, A.4
  • 41
    • 35848965042 scopus 로고    scopus 로고
    • Dynamics of lactate concentration and blood oxygen level-dependent effect in the human visual cortex during repeated identical stimuli
    • Mangia, S., Tkac, I., Logothetis, N. K., Gruetter, R., Van De Moortele, P. F., and Ugurbil, K. (2007). Dynamics of lactate concentration and blood oxygen level-dependent effect in the human visual cortex during repeated identical stimuli. J. Neurosci. Res. 85, 3340-3346. doi: 10.1002/jnr.21371
    • (2007) J. Neurosci. Res , vol.85 , pp. 3340-3346
    • Mangia, S.1    Tkac, I.2    Logothetis, N.K.3    Gruetter, R.4    Van De Moortele, P.F.5    Ugurbil, K.6
  • 42
    • 84892176412 scopus 로고    scopus 로고
    • Glutamate pays its own way in astrocytes
    • McKenna, M. C. (2013). Glutamate pays its own way in astrocytes. Front. Endocrinol. 4:191. doi: 10.3389/fendo.2013.00191
    • (2013) Front. Endocrinol. , vol.4 , pp. 191
    • McKenna, M.C.1
  • 43
    • 0035576881 scopus 로고    scopus 로고
    • Alpha-cyano-4-hydroxycinnamate decreases both glucose and lactate metabolism in neurons and astrocytes: implications for lactate as an energy substrate for neurons
    • McKenna, M. C., Hopkins, I. B., and Carey, A. (2001). Alpha-cyano-4-hydroxycinnamate decreases both glucose and lactate metabolism in neurons and astrocytes: implications for lactate as an energy substrate for neurons. J. Neurosci. Res. 66, 747-754. doi: 10.1002/jnr.10084
    • (2001) J. Neurosci. Res , vol.66 , pp. 747-754
    • McKenna, M.C.1    Hopkins, I.B.2    Carey, A.3
  • 44
    • 0030061356 scopus 로고    scopus 로고
    • Exogenous glutamate concentration regulates the metabolic fate of glutamate in astrocytes
    • McKenna, M. C., Sonnewald, U., Huang, X., Stevenson, J., and Zielke, H. R. (1996). Exogenous glutamate concentration regulates the metabolic fate of glutamate in astrocytes. J. Neurochem. 66, 386-393. doi: 10.1046/j.1471-4159.1996.66010386.x
    • (1996) J. Neurochem , vol.66 , pp. 386-393
    • McKenna, M.C.1    Sonnewald, U.2    Huang, X.3    Stevenson, J.4    Zielke, H.R.5
  • 45
    • 0018558116 scopus 로고
    • Central catecholamine neuron systems: anatomy and physiology of the norepinephrine and epinephrine systems
    • Moore, R. Y., and Bloom, F. E. (1979). Central catecholamine neuron systems: anatomy and physiology of the norepinephrine and epinephrine systems. Annu. Rev. Neurosci. 2, 113-168. doi: 10.1146/annurev.ne.02.030179.000553
    • (1979) Annu. Rev. Neurosci , vol.2 , pp. 113-168
    • Moore, R.Y.1    Bloom, F.E.2
  • 46
    • 0022505025 scopus 로고
    • Acetate and fluoroacetate as possible markers for glial metabolism in vivo
    • Muir, D., Berl, S., and Clarke, D. D. (1986). Acetate and fluoroacetate as possible markers for glial metabolism in vivo. Brain Res. 380, 336-340. doi: 10.1016/0006-8993(86)90231-3
    • (1986) Brain Res , vol.380 , pp. 336-340
    • Muir, D.1    Berl, S.2    Clarke, D.D.3
  • 47
    • 84865482241 scopus 로고    scopus 로고
    • Overview of pyridine nucleotides review series
    • Nakamura, M., Bhatnagar, A., and Sadoshima, J. (2012). Overview of pyridine nucleotides review series. Circ. Res. 111, 604-610. doi: 10.1161/circresaha.111.247924
    • (2012) Circ. Res , vol.111 , pp. 604-610
    • Nakamura, M.1    Bhatnagar, A.2    Sadoshima, J.3
  • 48
    • 0027244386 scopus 로고
    • Carrier-mediated transport of lactic acid in cultured neurons and astrocytes
    • Nedergaard, M., and Goldman, S. A. (1993). Carrier-mediated transport of lactic acid in cultured neurons and astrocytes. Am. J. Physiol. 265, R282-R289.
    • (1993) Am. J. Physiol. , vol.265 , pp. R282-R289
    • Nedergaard, M.1    Goldman, S.A.2
  • 49
    • 84883652625 scopus 로고    scopus 로고
    • Techniques and strategies in neurocritical care originating from southern Scandinavia
    • Nordström, C. H., Nielsen, T. H., and Jacobsen, A. (2013). Techniques and strategies in neurocritical care originating from southern Scandinavia. J. Rehabil. Med. 45, 710-717. doi: 10.2340/16501977-1157
    • (2013) J. Rehabil. Med , vol.45 , pp. 710-717
    • Nordström, C.H.1    Nielsen, T.H.2    Jacobsen, A.3
  • 50
    • 10644285757 scopus 로고    scopus 로고
    • Neuroglial metabolism in the awake rat brain: CO2 fixation increases with brain activity
    • öz, G., Berkich, D. A., Henry, P. G., Xu, Y., Lanoue, K., Hutson, S. M., et al. (2004). Neuroglial metabolism in the awake rat brain: CO2 fixation increases with brain activity. J. Neurosci. 24, 11273-11279. doi: 10.1523/JNEUROSCI.3564-04.2004
    • (2004) J. Neurosci , vol.24 , pp. 11273-11279
    • Öz, G.1    Berkich, D.A.2    Henry, P.G.3    Xu, Y.4    Lanoue, K.5    Hutson, S.M.6
  • 51
    • 78650897135 scopus 로고    scopus 로고
    • Brain glutamine synthesis requires neuronal-born aspartate as amino donor for glial glutamate formation
    • Pardo, B., Rodrigues, T. B., Contreras, L., Garzon, M., Llorente-Folch, I., Kobayashi, K., et al. (2011). Brain glutamine synthesis requires neuronal-born aspartate as amino donor for glial glutamate formation. J. Cereb. Blood Flow Metab. 31, 90-101. doi: 10.1038/jcbfm.2010.146
    • (2011) J. Cereb. Blood Flow Metab , vol.31 , pp. 90-101
    • Pardo, B.1    Rodrigues, T.B.2    Contreras, L.3    Garzon, M.4    Llorente-Folch, I.5    Kobayashi, K.6
  • 52
    • 0028046768 scopus 로고
    • High extracellular potassium concentrations stimulate oxidative metabolism in a glutamatergic neuronal culture and glycolysis in cultured astrocytes but have no stimulatory effect in a GABAergic neuronal culture
    • Peng, L., Zhang, X., and Hertz, L. (1994). High extracellular potassium concentrations stimulate oxidative metabolism in a glutamatergic neuronal culture and glycolysis in cultured astrocytes but have no stimulatory effect in a GABAergic neuronal culture. Brain Res. 663, 168-172. doi: 10.1016/0006-8993(94)90475-8
    • (1994) Brain Res , vol.663 , pp. 168-172
    • Peng, L.1    Zhang, X.2    Hertz, L.3
  • 53
    • 0027418622 scopus 로고
    • Transport of lactate and other monocarboxylates across mammalian plasma membranes
    • Poole, R. C., and Halestrap, A. P. (1993). Transport of lactate and other monocarboxylates across mammalian plasma membranes. Am. J. Physiol. 264, C761-C782.
    • (1993) Am. J. Physiol. , vol.264 , pp. C761-C782
    • Poole, R.C.1    Halestrap, A.P.2
  • 54
    • 54049143854 scopus 로고    scopus 로고
    • Lactate fuels the human brain during exercise
    • Quistorff, B., Secher, N. H., and Van Lieshout, J. J. (2008). Lactate fuels the human brain during exercise. FASEB J. 22, 3443-3449. doi: 10.1096/fj.08-106104
    • (2008) FASEB J , vol.22 , pp. 3443-3449
    • Quistorff, B.1    Secher, N.H.2    Van Lieshout, J.J.3
  • 55
    • 84857913840 scopus 로고    scopus 로고
    • Ca2+ signals of astrocytes are modulated by the NAD+/NADH redox state
    • Requardt, R. P., Hirrlinger, P. G., Wilhelm, F., Winkler, U., Besser, S., and Hirrlinger, J. (2012). Ca2+ signals of astrocytes are modulated by the NAD+/NADH redox state. J. Neurochem. 120, 1014-1025. doi: 10.1111/j.1471-4159.2012.07645.x
    • (2012) J. Neurochem , vol.120 , pp. 1014-1025
    • Requardt, R.P.1    Hirrlinger, P.G.2    Wilhelm, F.3    Winkler, U.4    Besser, S.5    Hirrlinger, J.6
  • 56
    • 0019554835 scopus 로고
    • Intracellular pH
    • Roos, A., and Boron, W. F. (1981). Intracellular pH. Physiol. Rev. 61, 296-434.
    • (1981) Physiol. Rev. , vol.61 , pp. 296-434
    • Roos, A.1    Boron, W.F.2
  • 57
    • 80052830781 scopus 로고    scopus 로고
    • 13C MRS studies of neuroenergetics and neurotransmitter cycling in humans
    • Rothman, D. L., De Feyter, H. M., De Graaf, R. A., Mason, G. F., and Behar, K. L. (2011). 13C MRS studies of neuroenergetics and neurotransmitter cycling in humans. NMR Biomed. 24, 943-957. doi: 10.1002/nbm.1772
    • (2011) NMR Biomed , vol.24 , pp. 943-957
    • Rothman, D.L.1    De Feyter, H.M.2    De Graaf, R.A.3    Mason, G.F.4    Behar, K.L.5
  • 58
    • 84874458753 scopus 로고    scopus 로고
    • A genetically encoded FRET lactate sensor and its use to detect the Warburg effect in single cancer cells
    • San Martin, A., Ceballo, S., Ruminot, I., Lerchundi, R., Frommer, W. B., and Barros, L. F. (2013). A genetically encoded FRET lactate sensor and its use to detect the Warburg effect in single cancer cells. PLoS ONE 8:e57712. doi: 10.1371/journal.pone.0057712
    • (2013) PLoS ONE , vol.8 , pp. e57712
    • San Martin, A.1    Ceballo, S.2    Ruminot, I.3    Lerchundi, R.4    Frommer, W.B.5    Barros, L.F.6
  • 59
    • 0036144176 scopus 로고    scopus 로고
    • Activation-induced resetting of cerebral metabolism and flow is abolished by beta-adrenergic blockade with propranolol
    • Schmalbruch, I. K., Linde, R., Paulson, O. B., and Madsen, P. L. (2002). Activation-induced resetting of cerebral metabolism and flow is abolished by beta-adrenergic blockade with propranolol. Stroke 33, 251-255. doi: 10.1161/hs0102.101233
    • (2002) Stroke , vol.33 , pp. 251-255
    • Schmalbruch, I.K.1    Linde, R.2    Paulson, O.B.3    Madsen, P.L.4
  • 62
    • 84860502652 scopus 로고    scopus 로고
    • Biochemical issues in estimation of cytosolic free NAD/NADH ratio
    • Sun, F., Dai, C., Xie, J., and Hu, X. (2012). Biochemical issues in estimation of cytosolic free NAD/NADH ratio. PLoS ONE 7:e34525. doi: 10.1371/journal.pone.0034525
    • (2012) PLoS ONE , vol.7 , pp. e34525
    • Sun, F.1    Dai, C.2    Xie, J.3    Hu, X.4
  • 63
    • 84904760530 scopus 로고    scopus 로고
    • Lactate-mediated glia-neuronal signalling in the mammalian brain
    • Tang, F., Lane, S., Korsak, A., Paton, J. F., Gourine, A. V., Kasparov, S., et al. (2014). Lactate-mediated glia-neuronal signalling in the mammalian brain. Nat. Commun. 5:3284. doi: 10.1038/ncomms4284
    • (2014) Nat. Commun. , vol.5 , pp. 3284
    • Tang, F.1    Lane, S.2    Korsak, A.3    Paton, J.F.4    Gourine, A.V.5    Kasparov, S.6
  • 65
    • 0015105242 scopus 로고
    • Metabolic characteristics of mitochondria isolated from rabbit brain
    • Von Korff, R. W., Steinman, S., and Welch, A. S. (1971). Metabolic characteristics of mitochondria isolated from rabbit brain. J. Neurochem. 18, 1577-1587. doi: 10.1111/j.1471-4159.1971.tb00019.x
    • (1971) J. Neurochem , vol.18 , pp. 1577-1587
    • Von Korff, R.W.1    Steinman, S.2    Welch, A.S.3
  • 66
    • 0032527892 scopus 로고    scopus 로고
    • Preferential utilization of acetate by astrocytes is attributable to transport
    • Waniewski, R. A., and Martin, D. L. (1998). Preferential utilization of acetate by astrocytes is attributable to transport. J. Neurosci. 18, 5225-5233.
    • (1998) J. Neurosci. , vol.18 , pp. 5225-5233
    • Waniewski, R.A.1    Martin, D.L.2
  • 67
    • 84885998103 scopus 로고    scopus 로고
    • Inhibitors of glutamate dehydrogenase block sodium-dependent glutamate uptake in rat brain membranes
    • Whitelaw, B. S., and Robinson, M. B. (2013). Inhibitors of glutamate dehydrogenase block sodium-dependent glutamate uptake in rat brain membranes. Front. Endocrinol. (Lausanne) 4:123. doi: 10.3389/fendo.2013.00123
    • (2013) Front. Endocrinol. (Lausanne) , vol.4 , pp. 123
    • Whitelaw, B.S.1    Robinson, M.B.2
  • 68
    • 84871433548 scopus 로고    scopus 로고
    • Multifunctional Roles of NAD(+) and NADH in Astrocytes
    • Wilhelm, F., and Hirrlinger, J. (2012). Multifunctional Roles of NAD(+) and NADH in Astrocytes. Neurochem. Res. 37, 2317-2325. doi: 10.1007/s11064-012-0760-y
    • (2012) Neurochem. Res , vol.37 , pp. 2317-2325
    • Wilhelm, F.1    Hirrlinger, J.2
  • 69
    • 33645730887 scopus 로고    scopus 로고
    • Extracellular lactate as a dynamic vasoactive signal in the rat retinal microvasculature
    • Yamanishi, S., Katsumura, K., Kobayashi, T., and Puro, D. G. (2006). Extracellular lactate as a dynamic vasoactive signal in the rat retinal microvasculature. Am. J. Physiol. Heart. Circ. Physiol. 290, H925-H934. doi: 10.1152/ajpheart.01012.2005
    • (2006) Am. J. Physiol. Heart. Circ. Physiol , vol.290 , pp. H925-H934
    • Yamanishi, S.1    Katsumura, K.2    Kobayashi, T.3    Puro, D.G.4
  • 70
    • 0020335372 scopus 로고
    • Metabolic fate of 14C-labeled glutamate in astrocytes in primary cultures
    • Yu, A. C., Schousboe, A., and Hertz, L. (1982). Metabolic fate of 14C-labeled glutamate in astrocytes in primary cultures. J. Neurochem. 39, 954-960. doi: 10.1111/j.1471-4159.1982.tb11482.x
    • (1982) J. Neurochem , vol.39 , pp. 954-960
    • Yu, A.C.1    Schousboe, A.2    Hertz, L.3


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