메뉴 건너뛰기




Volumn 66, Issue 1, 1996, Pages 386-393

Exogenous glutamate concentration regulates the metabolic fate of glutamate in astrocytes

Author keywords

13C NMR spectroscopy; Astrocytes; Energy metabolism; Glutamine; Lactate; U 13C Glutamate

Indexed keywords

GLUTAMIC ACID;

EID: 0030061356     PISSN: 00223042     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1471-4159.1996.66010386.x     Document Type: Article
Times cited : (336)

References (42)
  • 1
    • 0026020414 scopus 로고
    • Fatty acid oxidation and ketogenesis by astrocytes in primary culture
    • Aueslad N., Korsak R. A., Morrow J. W., and Edmond J. (1991) Fatty acid oxidation and ketogenesis by astrocytes in primary culture. J. Neurochem. 56, 1376-1386.
    • (1991) J. Neurochem. , vol.56 , pp. 1376-1386
    • Aueslad, N.1    Korsak, R.A.2    Morrow, J.W.3    Edmond, J.4
  • 2
    • 0342316047 scopus 로고
    • 13C] glutamate to glutamine and lactate in cortical slices: An NMR study
    • 13C] glutamate to glutamine and lactate in cortical slices: an NMR study. (Abstr.) J. Neurochem. 63 (Suppl.), S48B.
    • (1994) J. Neurochem. , vol.63 , Issue.SUPPL.
    • Bachelard, H.1    Morris, P.2    Taylor, A.3
  • 5
    • 0015297282 scopus 로고
    • An improved colour reagent for the determination of blood glucose by the oxidase system
    • Barbara D. and Trinder P. (1972) An improved colour reagent for the determination of blood glucose by the oxidase system. Analyst 97, 142.
    • (1972) Analyst , vol.97 , pp. 142
    • Barbara, D.1    Trinder, P.2
  • 6
    • 0015447985 scopus 로고
    • Growth and cultivation of dissociated neurons and glial cells from embryonic chick, rat and human brain in flask cultures
    • Booher J. and Sensenbrenner M. (1972) Growth and cultivation of dissociated neurons and glial cells from embryonic chick, rat and human brain in flask cultures. Neurobiology 2, 97-105.
    • (1972) Neurobiology , vol.2 , pp. 97-105
    • Booher, J.1    Sensenbrenner, M.2
  • 7
    • 0025196959 scopus 로고
    • Metabolism and role of glutamate in mammalian brain
    • Erecińska M. and Silver I. A. (1990) Metabolism and role of glutamate in mammalian brain. Prog. Neurobiol. 35, 245-296.
    • (1990) Prog. Neurobiol. , vol.35 , pp. 245-296
    • Erecińska, M.1    Silver, I.A.2
  • 8
    • 0026668151 scopus 로고
    • Glutamate metabolism in rat cortical astrocyte cultures
    • Farinelli S. E. and Nicklas W. J. (1992) Glutamate metabolism in rat cortical astrocyte cultures. J. Neurochem. 58, 1905-1915.
    • (1992) J. Neurochem. , vol.58 , pp. 1905-1915
    • Farinelli, S.E.1    Nicklas, W.J.2
  • 10
    • 0018670663 scopus 로고
    • Functional interactions between neurons and astrocytes. I. Turnover and metabolism of putative amino acid neurotransmitters
    • Hertz L. (1979) Functional interactions between neurons and astrocytes. I. Turnover and metabolism of putative amino acid neurotransmitters. Prog. Neurobiol. 13, 277-323.
    • (1979) Prog. Neurobiol. , vol.13 , pp. 277-323
    • Hertz, L.1
  • 11
    • 0027465673 scopus 로고
    • Purification of cytosolic malic enzyme from bovine brain, generation of monoclonal antibodies, and immunocytochemical localization of the enzyme in glial cells of neural primary cultures
    • Kurz G. M., Weisinger H., and Hamprecht B. (1993) Purification of cytosolic malic enzyme from bovine brain, generation of monoclonal antibodies, and immunocytochemical localization of the enzyme in glial cells of neural primary cultures. J. Neurochem. 60, 1467-1474.
    • (1993) J. Neurochem. , vol.60 , pp. 1467-1474
    • Kurz, G.M.1    Weisinger, H.2    Hamprecht, B.3
  • 12
    • 0026701548 scopus 로고
    • Extracellular intermediates of glucose metabolism: Fluxes of endogenous lactate and alanine through extracellular pools in embryonic sympathetic ganglia
    • Larrabee M. G. (1992) Extracellular intermediates of glucose metabolism: fluxes of endogenous lactate and alanine through extracellular pools in embryonic sympathetic ganglia. J. Neurochem. 59, 1041-1052.
    • (1992) J. Neurochem. , vol.59 , pp. 1041-1052
    • Larrabee, M.G.1
  • 15
    • 0027727915 scopus 로고
    • Regulation of energy metabolism in synaptic terminals and cultured rat brain astrocytes: Differences revealed using aminooxyacetate
    • McKenna M. C., Tildon J. T., Stevenson J. H. Jr., Boatright R., and Huang S. (1993) Regulation of energy metabolism in synaptic terminals and cultured rat brain astrocytes: differences revealed using aminooxyacetate. Dev. Neurosci. 15, 320-329.
    • (1993) Dev. Neurosci. , vol.15 , pp. 320-329
    • McKenna, M.C.1    Tildon, J.T.2    Stevenson Jr., J.H.3    Boatright, R.4    Huang, S.5
  • 16
    • 0028658335 scopus 로고
    • Energy metabolism in cortical synaptic terminals from weanling and mature rat brain: Evidence for multiple compartments of tricarboxylic acid cycle activity
    • McKenna M. C., Tildon J. T., Stevenson J. H., and Hopkins I. B. (1994) Energy metabolism in cortical synaptic terminals from weanling and mature rat brain: evidence for multiple compartments of tricarboxylic acid cycle activity. Dev. Neurosci. 16, 291-300.
    • (1994) Dev. Neurosci. , vol.16 , pp. 291-300
    • McKenna, M.C.1    Tildon, J.T.2    Stevenson, J.H.3    Hopkins, I.B.4
  • 17
    • 0025777874 scopus 로고
    • Utilization of alpha-ketoglutarate as a precursor for transmitter glutamate in cultured cerebellar granular cells
    • Peng L., Schousboe A., and Hertz L. (1991) Utilization of alpha-ketoglutarate as a precursor for transmitter glutamate in cultured cerebellar granular cells. Neurochem. Res. 16, 29-34.
    • (1991) Neurochem. Res. , vol.16 , pp. 29-34
    • Peng, L.1    Schousboe, A.2    Hertz, L.3
  • 18
    • 0017718021 scopus 로고
    • Uptake and metabolism of glutamate in astrocytes cultured from dissociated mouse brain hemispheres
    • Schousboe A., Svenneby G., and Hertz L. (1977) Uptake and metabolism of glutamate in astrocytes cultured from dissociated mouse brain hemispheres. J. Neurochem. 29, 999-1005.
    • (1977) J. Neurochem. , vol.29 , pp. 999-1005
    • Schousboe, A.1    Svenneby, G.2    Hertz, L.3
  • 20
    • 0023890868 scopus 로고
    • Lactate-supported synaptic function in the rat hippocampal slice preparation
    • Schurr A., West C. A., and Rigor B. M. (1988) Lactate-supported synaptic function in the rat hippocampal slice preparation. Science 240, 1326-1328.
    • (1988) Science , vol.240 , pp. 1326-1328
    • Schurr, A.1    West, C.A.2    Rigor, B.M.3
  • 21
    • 0024591219 scopus 로고
    • Electrophysiology of energy metabolism and neuronal function in the hippocampal slice preparation
    • Schurr A., West C. A., and Rigor B. M. (1989) Electrophysiology of energy metabolism and neuronal function in the hippocampal slice preparation. J. Neurosci. Methods 28, 7-13.
    • (1989) J. Neurosci. Methods , vol.28 , pp. 7-13
    • Schurr, A.1    West, C.A.2    Rigor, B.M.3
  • 22
    • 0019482340 scopus 로고
    • Present status and significance of the glutamine cycle in neural tissue
    • Shank R. P. and Aprison M. (1981) Present status and significance of the glutamine cycle in neural tissue. Life Sci. 28, 837-842.
    • (1981) Life Sci. , vol.28 , pp. 837-842
    • Shank, R.P.1    Aprison, M.2
  • 23
    • 85052772258 scopus 로고
    • Glutamate as a neurotransmitter
    • Kvamme E., ed. CRC Press, Boca Raton, Florida
    • Shank R. P. and Aprison M. (1988) Glutamate as a neurotransmitter, in Glutamate and Glutamine in Mammals, Vol. 2 (Kvamme E., ed), pp. 3-20. CRC Press, Boca Raton, Florida.
    • (1988) Glutamate and Glutamine in Mammals, Vol. 2 , vol.2 , pp. 3-20
    • Shank, R.P.1    Aprison, M.2
  • 24
    • 0019991447 scopus 로고
    • Glutamine and α-ketoglutarate uptake and metabolism by nerve terminal enriched material from mouse cerebellum
    • Shank R. P. and Campbell G. LeM. (1982) Glutamine and α-ketoglutarate uptake and metabolism by nerve terminal enriched material from mouse cerebellum. Neurochem. Res. 7, 601-611.
    • (1982) Neurochem. Res. , vol.7 , pp. 601-611
    • Shank, R.P.1    Campbell, G.LeM.2
  • 25
    • 0021332488 scopus 로고
    • α-Ketoglutarate and malate uptake and metabolism by synaptosomes: Further evidence for an astrocyte-to-neuron metabolic shuttle
    • Shank R. P. and Campbell G. LeM. (1984) α-Ketoglutarate and malate uptake and metabolism by synaptosomes: further evidence for an astrocyte-to-neuron metabolic shuttle. J. Neurochem. 42, 1153-1161.
    • (1984) J. Neurochem. , vol.42 , pp. 1153-1161
    • Shank, R.P.1    Campbell, G.L.2
  • 29
    • 0027338137 scopus 로고
    • 13C NMR spectroscopy: Incorporation of more label into lactate than into glutamine demonstrates the importance of the tricarboxylic acid cycle
    • 13C NMR spectroscopy: incorporation of more label into lactate than into glutamine demonstrates the importance of the tricarboxylic acid cycle. J. Neurochem. 61, 1179-1182.
    • (1993) J. Neurochem. , vol.61 , pp. 1179-1182
    • Sonnewald, U.1    Westergaard, N.2    Petersen, S.B.3    Unsgård, G.4    Schousboe, A.5
  • 31
    • 0003072603 scopus 로고
    • Determination of glucose in blood using glucose oxidase with an alternative oxygen acceptor
    • Trinder P. (1969) Determination of glucose in blood using glucose oxidase with an alternative oxygen acceptor. Ann. Clin. Biochem. 6, 24.
    • (1969) Ann. Clin. Biochem. , vol.6 , pp. 24
    • Trinder, P.1
  • 32
    • 0024260649 scopus 로고
    • Lactate release from cultured astrocytes and neurons: A comparison
    • Walz W. and Mukerji S. (1988) Lactate release from cultured astrocytes and neurons: a comparison. Glia 1, 366-370.
    • (1988) Glia , vol.1 , pp. 366-370
    • Walz, W.1    Mukerji, S.2
  • 33
    • 0026595752 scopus 로고
    • Physiological levels of ammonia regulate glutamine synthesis from extracellular glutamate in astrocyte cultures
    • Waniewski R. A. (1992) Physiological levels of ammonia regulate glutamine synthesis from extracellular glutamate in astrocyte cultures. J. Neurochem. 58, 167-174.
    • (1992) J. Neurochem. , vol.58 , pp. 167-174
    • Waniewski, R.A.1
  • 34
    • 0022478666 scopus 로고
    • Exogenous glutamate is metabolized to glutamine and exported by rat primary astrocyte cultures
    • Waniewski R. A. and Martin D. L. (1986) Exogenous glutamate is metabolized to glutamine and exported by rat primary astrocyte cultures. J. Neurochem. 47, 304-313.
    • (1986) J. Neurochem. , vol.47 , pp. 304-313
    • Waniewski, R.A.1    Martin, D.L.2
  • 36
    • 0020335372 scopus 로고
    • 14C-labelled glutamate in astrocytes in primary cultures
    • 14C-labelled glutamate in astrocytes in primary cultures. J. Neurochem. 39, 954-960.
    • (1982) J. Neurochem. , vol.39 , pp. 954-960
    • Yu, A.C.1    Schousboe, A.2    Hertz, L.3
  • 37
    • 0023820776 scopus 로고
    • 15N]glutamine: Implications for the glutamine-glutamate cycle
    • 15N]glutamine: implications for the glutamine-glutamate cycle. J. Neurochem. 51, 843-850.
    • (1988) J. Neurochem. , vol.51 , pp. 843-850
    • Yudkoff, M.1    Nissim, I.2    Pleasure, D.3
  • 39
    • 0027080877 scopus 로고
    • Nitrogen metabolism: Neuronal-astroglial relationships
    • Yu A. C. H., Hertz L., Norenberg M. D., Sykova E., and Waxman S. G., eds. Elsevier Science Publishers, Amsterdam
    • Yudkoff M., Nissim I., Hertz L., Pleasure D., and Erecińska M. (1992) Nitrogen metabolism: neuronal-astroglial relationships, in Progress in Brain Research, Vol. 94 (Yu A. C. H., Hertz L., Norenberg M. D., Sykova E., and Waxman S. G., eds), pp. 213-224. Elsevier Science Publishers, Amsterdam.
    • (1992) Progress in Brain Research, Vol. 94 , vol.94 , pp. 213-224
    • Yudkoff, M.1    Nissim, I.2    Hertz, L.3    Pleasure, D.4    Erecińska, M.5
  • 42
    • 0025613128 scopus 로고
    • Effect of 8-bromo-cAMP and dexamethasone on glutamate metabolism in rat astrocytes
    • Zielke H. R., Tildon J. T., Landry M. E., and Max S. R. (1990) Effect of 8-bromo-cAMP and dexamethasone on glutamate metabolism in rat astrocytes. Neurochem. Res. 15, 1115-1122.
    • (1990) Neurochem. Res. , vol.15 , pp. 1115-1122
    • Zielke, H.R.1    Tildon, J.T.2    Landry, M.E.3    Max, S.R.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.