High-glucose inhibits human fibroblast cell migration in wound healing via repression of bFGF-regulating JNK phosphorylation

PLoS ONE

Volumn 9, Issue 9, 2014, Pages

  Xuan, Yuan Hu ^a   Huang, Bin Bin ^a   Tian, Hai Shan ^a   Chi, Li Sha ^a   Duan, Yuan Meng ^a   Wang, Xi ^a   Zhu, Zhong Xin ^a   Cai, Wan Hui ^a   Zhu, Yu Ting ^a   Wei, Tie Min ^a   Ye, Hong Bo ^b   Cong, Wei Tao ^a   Jin, Li Tai ^a  

^a WENZHOU MEDICAL UNIVERSITY   (China)

^b STANFORD UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

1 TERT BUTYL 3 [6 (3,5 DIMETHOXYPHENYL) 2 (4 DIETHYLAMINOBUTYLAMINO)PYRIDO[2,3 D]PYRIMIDIN 7 YL]UREA; 3 NITROTYROSINE; ANTHRA[1,9 CD]PYRAZOL 6(2H) ONE; FIBROBLAST GROWTH FACTOR 2; FIBROBLAST GROWTH FACTOR RECEPTOR 1; GLUCOSE; LIPOCORTIN 2; PLASMINOGEN ACTIVATOR INHIBITOR 1; RAC1 PROTEIN; REACTIVE OXYGEN METABOLITE; STRESS ACTIVATED PROTEIN KINASE; SUPEROXIDE; TUMOR NECROSIS FACTOR ALPHA; MITOGEN ACTIVATED PROTEIN KINASE KINASE 4;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL MIGRATION; CELL PROLIFERATION; CONTROLLED STUDY; FIBROBLAST; HUMAN; HUMAN CELL; INFLAMMATION; INSULIN DEPENDENT DIABETES MELLITUS; MALE; MIGRATION INHIBITION; NITRATION; NONHUMAN; PROTEIN PHOSPHORYLATION; PROTEOMICS; RAT; SIGNAL TRANSDUCTION; SKIN INJURY; WOUND HEALING; ANIMAL; CELL CULTURE; CELL MOTION; COMPLICATION; CYTOLOGY; DRUG EFFECTS; EXPERIMENTAL DIABETES MELLITUS; METABOLISM; PHOSPHORYLATION;

ANIMALS; APOPTOSIS; CELL MOVEMENT; CELLS, CULTURED; DIABETES MELLITUS, EXPERIMENTAL; FIBROBLAST GROWTH FACTOR 2; FIBROBLASTS; GLUCOSE; HUMANS; MAP KINASE KINASE 4; PHOSPHORYLATION; RATS; WOUND HEALING;

EID: 84907908976     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0108182     Document Type: Article

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