Metallothionein prevents diabetes-induced cardiac pathological changes, likely via the inhibition of succinyl-CoA:3-ketoacid coenzyme A transferase-1 nitration at Trp374

American Journal of Physiology - Endocrinology and Metabolism

Volumn 304, Issue 8, 2013, Pages

  Cong, Weitao ^a   Ma, Weide ^a,b   Zhao, Ting ^a   Zhu, Zhongxin ^a   Wang, Yuehui ^c   Tan, Yi ^a,d   Li, Xiaokun ^a   Jin, Litai ^a   Cai, Lu ^a,d  

^a WENZHOU MEDICAL UNIVERSITY   (China)

^b WENZHOU PEOPLE'S HOSPITAL   (China)

^c THE SECOND HOSPITAL OF JILIN UNIVERSITY   (China)

^d University of Louisville School of Medicine   (United States)

Author keywords

3 nitrotyrosine; Cardiac pathological changes; Diabetes; Metallothionein; SCOT

Indexed keywords

3 NITROTYROSINE; 3 OXOACID COENZYME A TRANSFERASE; METALLOTHIONEIN; SUCCINYL COA:3 KETOACID COENZYME A TRANSFERASE 1; SUPEROXIDE; TRYPTOPHAN; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CATALYSIS; CONTROLLED STUDY; DIABETIC CARDIOMYOPATHY; ENZYME ACTIVE SITE; ENZYME INHIBITION; HISTOPATHOLOGY; MALE; MASS SPECTROMETRY; MOUSE; NITRATION; NITROSATIVE STRESS; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN STRUCTURE; STREPTOZOCIN DIABETES; WILD TYPE;

ANIMALS; COENZYME A-TRANSFERASES; DIABETES MELLITUS, EXPERIMENTAL; DISEASE MODELS, ANIMAL; ENERGY METABOLISM; HEART DISEASES; MALE; METALLOTHIONEIN; MICE; MICE, INBRED STRAINS; MICE, TRANSGENIC; MYOCARDIUM; NITROGEN; PROTEIN STRUCTURE, TERTIARY; SUPEROXIDES; TRYPTOPHAN; TYROSINE;

EID: 84878492166     PISSN: 01931849     EISSN: 15221555     Source Type: Journal    
DOI: 10.1152/ajpendo.00570.2012     Document Type: Article

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