메뉴 건너뛰기




Volumn 7, Issue , 2014, Pages 251-259

Targeting of interleukin-17 in the treatment of psoriasis

Author keywords

Anti IL 17 agents; Brodalumab; IL 17; Ixekizumab; Psoriasis; Secukinumab

Indexed keywords

ASPARTATE AMINOTRANSFERASE; BRODALUMAB; CREATINE KINASE; ETANERCEPT; INTERLEUKIN 17 RECEPTOR; IXEKIZUMAB; PLACEBO; SECUKINUMAB; USTEKINUMAB;

EID: 84907876102     PISSN: None     EISSN: 11787015     Source Type: Journal    
DOI: 10.2147/CCID.S67534     Document Type: Review
Times cited : (77)

References (59)
  • 4
    • 33745727343 scopus 로고    scopus 로고
    • Epidemiology of psoriasis. Review and the German perspective
    • Schäfer T. Epidemiology of psoriasis. Review and the German perspective. Dermatology. 2006;212(4):327-337.
    • (2006) Dermatology , vol.212 , Issue.4 , pp. 327-337
    • Schäfer, T.1
  • 5
    • 77749334805 scopus 로고    scopus 로고
    • Assessment of risk of psoriatic arthritis in patients with plaque psoriasis: A systematic review of the literature
    • Prey S, Paul C, Bronsard V, et al. Assessment of risk of psoriatic arthritis in patients with plaque psoriasis: a systematic review of the literature. J Eur Acad Dermatol Venereol. 2012;24 Suppl 2:31-35.
    • J Eur Acad Dermatol Venereol. 2012;24 Suppl , vol.2 , pp. 31-35
    • Prey, S.1    Paul, C.2    Bronsard, V.3
  • 6
    • 64849094127 scopus 로고    scopus 로고
    • Epidemiology and clinical pattern of psoriatic arthritis in Germany: A prospective interdisciplinary epidemiological study of 1511 patients with plaque-type psoriasis
    • Reich K, Krüger K, Mössner R, Augustin M. Epidemiology and clinical pattern of psoriatic arthritis in Germany: a prospective interdisciplinary epidemiological study of 1511 patients with plaque-type psoriasis. Br J Dermatol. 2009;160(5):1040-1047.
    • (2009) Br J Dermatol , vol.160 , Issue.5 , pp. 1040-1047
    • Reich, K.1    Krüger, K.2    Mössner, R.3    Augustin, M.4
  • 7
    • 77749334815 scopus 로고    scopus 로고
    • Cardiovascular risk factors in patients with plaque psoriasis: A systematic review of epidemiological studies
    • Prey S, Paul C, Bronsard V, et al. Cardiovascular risk factors in patients with plaque psoriasis: a systematic review of epidemiological studies. J Eur Acad Dermatol Venereol. 2010;24(Suppl 2):23-30.
    • (2010) J Eur Acad Dermatol Venereol , vol.24 , pp. 23-30
    • Prey, S.1    Paul, C.2    Bronsard, V.3
  • 8
    • 77955868163 scopus 로고    scopus 로고
    • The risk of depression, anxiety, and suicidality in patients with psoriasis: A population-based cohort study
    • Kurd SK, Troxel AB, Crits-Christoph P, Gelfand JM. The risk of depression, anxiety, and suicidality in patients with psoriasis: a population-based cohort study. Arch Dermatol. 2010;146(8):891-895.
    • (2010) Arch Dermatol , vol.146 , Issue.8 , pp. 891-895
    • Kurd, S.K.1    Troxel, A.B.2    Crits-Christoph, P.3    Gelfand, J.M.4
  • 9
    • 1842555395 scopus 로고    scopus 로고
    • Psoriasis is common, carries a substantial burden even when not extensive, and is associated with widespread treatment dissatisfaction
    • Stern RS, Nijsten T, Feldman SR, Margolis DJ, Rolstad T. Psoriasis is common, carries a substantial burden even when not extensive, and is associated with widespread treatment dissatisfaction. J Investig Dermatol Symp Proc. 2004;9(2):136-139.
    • (2004) J Investig Dermatol Symp Proc , vol.9 , Issue.2 , pp. 136-139
    • Stern, R.S.1    Nijsten, T.2    Feldman, S.R.3    Margolis, D.J.4    Rolstad, T.5
  • 10
    • 36049001754 scopus 로고    scopus 로고
    • Quality of life in patients with psoriasis and psoriasis arthritis with a special focus on stigmatization experience
    • Schmid-Ott G, Schallmayer S, Calliess IT. Quality of life in patients with psoriasis and psoriasis arthritis with a special focus on stigmatization experience. Clin Dermatol. 2007;25(6):547-554.
    • (2007) Clin Dermatol , vol.25 , Issue.6 , pp. 547-554
    • Schmid-Ott, G.1    Schallmayer, S.2    Calliess, I.T.3
  • 12
    • 84870512735 scopus 로고    scopus 로고
    • Collaborative Association Study of Psoriasis (CASP); Genetic Analysis of Psoriasis Consortium; Psoriasis Association Genetics Extension; Wellcome Trust Case Control Consortium 2, et al. Identification of 15 new psoriasis susceptibility loci highlights the role of innate immunity
    • Tsoi LC, Spain SL, Knight J, et al; Collaborative Association Study of Psoriasis (CASP); Genetic Analysis of Psoriasis Consortium; Psoriasis Association Genetics Extension; Wellcome Trust Case Control Consortium 2, et al. Identification of 15 new psoriasis susceptibility loci highlights the role of innate immunity. Nat Genet. 2012;44(12):1341-1348.
    • (2012) Nat Genet , vol.44 , Issue.12 , pp. 1341-1348
    • Tsoi, L.C.1    Spain, S.L.2    Knight, J.3
  • 13
    • 1842422281 scopus 로고    scopus 로고
    • The genetics of psoriasis, psoriatic arthritis and atopic dermatitis
    • Spec
    • Bowcock AM, Cookson WO. The genetics of psoriasis, psoriatic arthritis and atopic dermatitis. Hum Mol Genet. 2004;13 Spec No 1: R43-R55.
    • (2004) Hum Mol Genet , vol.13 , Issue.1 , pp. R43-R55
    • Bowcock, A.M.1    Cookson, W.O.2
  • 14
    • 84856934199 scopus 로고    scopus 로고
    • Psoriasis and other complex trait dermatoses: From Loci to functional pathways
    • Carpon F, Burden AD, Trembath RC, Barker JN. Psoriasis and other complex trait dermatoses: from Loci to functional pathways. J Invest Dermatol. 2012;132(3 Pt 2):915-922.
    • (2012) J Invest Dermatol , vol.132 , Issue.3 , pp. 915-922
    • Carpon, F.1    Burden, A.D.2    Trembath, R.C.3    Barker, J.N.4
  • 15
    • 79955769482 scopus 로고    scopus 로고
    • A genetic risk score combining ten psoriasis risk loci improves disease prediction
    • Chen H, Poon A, Yeung C, et al. A genetic risk score combining ten psoriasis risk loci improves disease prediction. PLoS One. 2011;6:e19454.
    • (2011) PLoS One , vol.6
    • Chen, H.1    Poon, A.2    Yeung, C.3
  • 16
    • 0031733127 scopus 로고    scopus 로고
    • Comparison of actual psoriasis surface area and the psoriasis area and severity index by the human eye and machine vision methods in following the treatment of psoriasis
    • Savolainen L, Kontinen J, Alatalo E, Röning J, Oikarinen A. Comparison of actual psoriasis surface area and the psoriasis area and severity index by the human eye and machine vision methods in following the treatment of psoriasis. Acta Derm Venereol. 1998;78(6):466-467.
    • (1998) Acta Derm Venereol , vol.78 , Issue.6 , pp. 466-467
    • Savolainen, L.1    Kontinen, J.2    Alatalo, E.3    Röning, J.4    Oikarinen, A.5
  • 17
    • 0032811347 scopus 로고    scopus 로고
    • Clinical measures of disease severity and outcome in psoriasis: A critical appraisal of their quality
    • Ashcroft DM, Wan Po AL, Williams HC, Griffiths CE. Clinical measures of disease severity and outcome in psoriasis: a critical appraisal of their quality. Br J Dermatol. 1999;141(2):185-191.
    • (1999) Br J Dermatol , vol.141 , Issue.2 , pp. 185-191
    • Ashcroft, D.M.1    Wan Po, A.L.2    Williams, H.C.3    Griffiths, C.E.4
  • 18
    • 34447249510 scopus 로고    scopus 로고
    • Treatment goals in psoriasis
    • English, German
    • Reich K, Mrowietz U. Treatment goals in psoriasis. J Dtsch Dermatol Ges. 2007;5(7):566-574. English, German.
    • (2007) J Dtsch Dermatol Ges , vol.5 , Issue.7 , pp. 566-574
    • Reich, K.1    Mrowietz, U.2
  • 19
    • 70249137988 scopus 로고    scopus 로고
    • European S3-guidelines on the systemic treatment of psoriasis vulgaris
    • Pathirana D, Ormerod AD, Saiag P, et al. European S3-guidelines on the systemic treatment of psoriasis vulgaris. J Eur Acad Dermatol Venereol. 2009;23 Suppl 2:1-70.
    • (2009) J Eur Acad Dermatol Venereol , vol.23 , pp. 1-70
    • Pathirana, D.1    Ormerod, A.D.2    Saiag, P.3
  • 20
    • 80053600391 scopus 로고    scopus 로고
    • Recent advances in the IL-17 cytokine family
    • Gaffen SL. Recent advances in the IL-17 cytokine family. Curr Opin Immunol. 2011;23(5):613-619.
    • (2011) Curr Opin Immunol , vol.23 , Issue.5 , pp. 613-619
    • Gaffen, S.L.1
  • 21
    • 68849084891 scopus 로고    scopus 로고
    • Structure and signaling in the IL-17 receptor family
    • Gaffen SL. Structure and signaling in the IL-17 receptor family. Nat Rev Immunol. 2009;9(8):556-567.
    • (2009) Nat Rev Immunol , vol.9 , Issue.8 , pp. 556-567
    • Gaffen, S.L.1
  • 22
    • 53149138236 scopus 로고    scopus 로고
    • The human IL-17F/IL-17A heterodimeric cytokine signals through the IL-17RA/IL-17RC receptor complex
    • Wright JF, Bennett F, Li B, et al. The human IL-17F/IL-17A heterodimeric cytokine signals through the IL-17RA/IL-17RC receptor complex. J Immunol. 2008;181(4):2799-2805.
    • (2008) J Immunol , vol.181 , Issue.4 , pp. 2799-2805
    • Wright, J.F.1    Bennett, F.2    Li, B.3
  • 24
    • 84866992632 scopus 로고    scopus 로고
    • Psoriasis: Rationale for targeting interleukin-17
    • Girolomoni G, Mrowietz U, Paul C. Psoriasis: rationale for targeting interleukin-17. Br J Dermatol. 2012;167(4):717-724.
    • (2012) Br J Dermatol , vol.167 , Issue.4 , pp. 717-724
    • Girolomoni, G.1    Mrowietz, U.2    Paul, C.3
  • 25
    • 84886067284 scopus 로고    scopus 로고
    • Th17 cells and IL-17 a - focus on immunopathogenesis and immunotherapeutics
    • van den Berg WB, McInnes IB. Th17 cells and IL-17 a - focus on immunopathogenesis and immunotherapeutics. Semin Arthritis Rheum. 2013;43:158-170.
    • (2013) Semin Arthritis Rheum , vol.43 , pp. 158-170
    • Van Den Berg, W.B.1    McInnes, I.B.2
  • 27
    • 79959584686 scopus 로고    scopus 로고
    • Mast cells and neutrophils release IL-17 through extracellular trap formation in psoriasis
    • Lin AM, Rubin CJ, Khandpur R, et al. Mast cells and neutrophils release IL-17 through extracellular trap formation in psoriasis. J Immunol. 2011;187(1):490-500.
    • (2011) J Immunol , vol.187 , Issue.1 , pp. 490-500
    • Lin, A.M.1    Rubin, C.J.2    Khandpur, R.3
  • 28
    • 45749101727 scopus 로고    scopus 로고
    • Induction and effector functions of T(H)17 cells
    • Bettelli E, Korn T, Oukka M, Kuchroo VK. Induction and effector functions of T(H)17 cells. Nature. 2008;453(7198):1051-1057.
    • (2008) Nature , vol.453 , Issue.7198 , pp. 1051-1057
    • Bettelli, E.1    Korn, T.2    Oukka, M.3    Kuchroo, V.K.4
  • 29
    • 47549112840 scopus 로고    scopus 로고
    • IL-21 and TGF-beta are required for differentiation of human T(H)17 cells
    • Yang L, Anderson DE, Baecher-Allan C, et al. IL-21 and TGF-beta are required for differentiation of human T(H)17 cells. Nature. 2008;454(7202):350-352.
    • (2008) Nature , vol.454 , Issue.7202 , pp. 350-352
    • Yang, L.1    Anderson, D.E.2    Baecher-Allan, C.3
  • 30
    • 58149296036 scopus 로고    scopus 로고
    • Interleukin-17 in host defence against bacterial, mycobacterial and fungal pathogens
    • Curtis MM, Way SS. Interleukin-17 in host defence against bacterial, mycobacterial and fungal pathogens. Immunology. 2009;126(2): 177-185.
    • (2009) Immunology , vol.126 , Issue.2 , pp. 177-185
    • Curtis, M.M.1    Way, S.S.2
  • 31
    • 79953284685 scopus 로고    scopus 로고
    • Chronic mucocutaneous candidiasis in humans with inborn errors of interleukin-17 immunity
    • Puel A, Cypowyj S, Bustamante J, et al. Chronic mucocutaneous candidiasis in humans with inborn errors of interleukin-17 immunity. Science. 2011;332(6025):65-68.
    • (2011) Science , vol.332 , Issue.6025 , pp. 65-68
    • Puel, A.1    Cypowyj, S.2    Bustamante, J.3
  • 32
    • 84864359374 scopus 로고    scopus 로고
    • Mucocutaneous candidiasis: The IL-17 pathway and implications for targeted immunotherapy
    • Huppler AR, Bishu S, Gaffen SL. Mucocutaneous candidiasis: the IL-17 pathway and implications for targeted immunotherapy. Arthritis Res Ther. 2012;14(4):217.
    • (2012) Arthritis Res Ther , vol.14 , Issue.4 , pp. 217
    • Huppler, A.R.1    Bishu, S.2    Gaffen, S.L.3
  • 33
    • 84861162719 scopus 로고    scopus 로고
    • Th17 cells in immunity to Candida albicans
    • Hernández-Santos N, Gaffen SL. Th17 cells in immunity to Candida albicans. Cell Host Microbe. 2012;11(5):425-435.
    • (2012) Cell Host Microbe , vol.11 , Issue.5 , pp. 425-435
    • Hernández-Santos, N.1    Gaffen, S.L.2
  • 34
    • 84907878013 scopus 로고    scopus 로고
    • Results after at least 52 weeks of open label treatment with ixekizumab, an anti-IL-17A monoclonal antibody, in a phase 2 study in chronic plaque psoriasis
    • Gordon K, Leonardi C, Braun D, et al. Results after at least 52 weeks of open label treatment with ixekizumab, an anti-IL-17A monoclonal antibody, in a phase 2 study in chronic plaque psoriasis. J Am Acad Dermatol. 2014;70(5 Supplement 1):AB183.
    • (2014) J Am Acad Dermatol , vol.70 , pp. AB183
    • Gordon, K.1    Leonardi, C.2    Braun, D.3
  • 35
    • 84866934694 scopus 로고    scopus 로고
    • Targeting IL-17 and TH17 cells in chronic inflammation
    • Miossec P, Kolls JK. Targeting IL-17 and TH17 cells in chronic inflammation. Nat Rev Drug Discov. 2012;11(10):763-776.
    • (2012) Nat Rev Drug Discov , vol.11 , Issue.10 , pp. 763-776
    • Miossec, P.1    Kolls, J.K.2
  • 37
    • 84876292569 scopus 로고    scopus 로고
    • Effect of IL-17A blockade with secukinumab in autoimmune diseases
    • Patel DD, Lee DM, Kolbinger F, Antoni C. Effect of IL-17A blockade with secukinumab in autoimmune diseases. Ann Rheum Dis. 2013; 72 Suppl 2:2116-2123.
    • (2013) Ann Rheum Dis , vol.72 , pp. 2116-2123
    • Patel, D.D.1    Lee, D.M.2    Kolbinger, F.3    Antoni, C.4
  • 40
    • 84872275425 scopus 로고    scopus 로고
    • The emerging role of IL-17 in the pathogenesis of psoriasis: Preclinical and clinical findings
    • Martin DA, Towne JE, Kricorian G, et al. The emerging role of IL-17 in the pathogenesis of psoriasis: preclinical and clinical findings. J Invest Dermatol. 2013;133(1):17-26.
    • (2013) J Invest Dermatol , vol.133 , Issue.1 , pp. 17-26
    • Martin, D.A.1    Towne, J.E.2    Kricorian, G.3
  • 41
    • 70349753261 scopus 로고    scopus 로고
    • Th17 cytokines stimulate CCL20 expression in keratinocytes in vitro and in vivo: Implications for psoriasis pathogenesis
    • Harper EG, Guo C, Rizzo H, et al. Th17 cytokines stimulate CCL20 expression in keratinocytes in vitro and in vivo: implications for psoriasis pathogenesis. J Invest Dermatol. 2009;129(9):2175-2183.
    • (2009) J Invest Dermatol , vol.129 , Issue.9 , pp. 2175-2183
    • Harper, E.G.1    Guo, C.2    Rizzo, H.3
  • 42
    • 84880790149 scopus 로고    scopus 로고
    • Therapeutic strategies in psoriasis patients with psoriatic arthritis: Focus on new agents
    • Gan EY, Chong WS, Tey HL. Therapeutic strategies in psoriasis patients with psoriatic arthritis: focus on new agents. BioDrugs. 2013;27(4):359-373.
    • (2013) BioDrugs , vol.27 , Issue.4 , pp. 359-373
    • Gan, E.Y.1    Chong, W.S.2    Tey, H.L.3
  • 43
    • 79961210510 scopus 로고    scopus 로고
    • The interleukin-17 cytokine family: Critical players in host defence and inflammatory diseases
    • Pappu R, Ramirez-Carrozzi V, Sambandam A. The interleukin-17 cytokine family: critical players in host defence and inflammatory diseases. Immunology. 2011;134(1):8-16.
    • (2011) Immunology , vol.134 , Issue.1 , pp. 8-16
    • Pappu, R.1    Ramirez-Carrozzi, V.2    Sambandam, A.3
  • 44
    • 84859017988 scopus 로고    scopus 로고
    • Brodalumab, an anti-interleukin-17-receptor antibody for psoriasis
    • Papp KA, Leonardi C, Menter A, et al. Brodalumab, an anti-interleukin-17-receptor antibody for psoriasis. N Engl J Med. 2012;366(13); 1181-1189.
    • (2012) N Engl J Med , vol.366 , Issue.13 , pp. 1181-1189
    • Papp, K.A.1    Leonardi, C.2    Menter, A.3
  • 45
    • 84907876101 scopus 로고    scopus 로고
    • Maintenance of clinical response with long-term brodalumab (AMG 827) therapy for psoriasis: Week 96 results from an open-label extension study
    • Papp K, Milmont C, Leonardi C, Ortonne JP, Klekotla P. Maintenance of clinical response with long-term brodalumab (AMG 827) therapy for psoriasis: Week 96 results from an open-label extension study. J Am Acad Dermatol. 2014;70(5 Suppl 1):AB174.
    • (2014) J Am Acad Dermatol , vol.70 , pp. AB174
    • Papp, K.1    Milmont, C.2    Leonardi, C.3    Ortonne, J.P.4    Klekotla, P.5
  • 46
    • 84866391313 scopus 로고    scopus 로고
    • Anti-IL-17 receptor antibody AMG 827 leads to rapid clinical response in subjects with moderate to severe psoriasis: Results from a phase I, randomized, placebo-controlled trial
    • Papp KA, Reid C, Foley P, et al. Anti-IL-17 receptor antibody AMG 827 leads to rapid clinical response in subjects with moderate to severe psoriasis: results from a phase I, randomized, placebo-controlled trial. J Invest Dermatol. 2012;132(10):2466-2469.
    • (2012) J Invest Dermatol , vol.132 , Issue.10 , pp. 2466-2469
    • Papp, K.A.1    Reid, C.2    Foley, P.3
  • 47
    • 77958072084 scopus 로고    scopus 로고
    • Effects of AIN457, a fully human antibody to interleukin-17A, on psoriasis, rheumatoid arthritis, and uveitis
    • Psoriasis Study Group, et al; Rheumatoid Arthritis Study Group, et al; Uveitis Study Group, et al
    • Hueber W, Patel DD, Dryja T, et al. Psoriasis Study Group, et al; Rheumatoid Arthritis Study Group, et al; Uveitis Study Group, et al. Effects of AIN457, a fully human antibody to interleukin-17A, on psoriasis, rheumatoid arthritis, and uveitis. Sci Transl Med. 2010;2(52):52-72.
    • (2010) Sci Transl Med , vol.2 , Issue.52 , pp. 52-72
    • Hueber, W.1    Patel, D.D.2    Dryja, T.3
  • 48
    • 84873124241 scopus 로고    scopus 로고
    • Efficacy and safety of secukinumab in the treatment of moderate-to-severe plaque psoriasis: A randomized, double-blind, placebo-controlled phase II dose-ranging study
    • Papp KA, Langley RG, Sigurgeirsson B, et al. Efficacy and safety of secukinumab in the treatment of moderate-to-severe plaque psoriasis: a randomized, double-blind, placebo-controlled phase II dose-ranging study. Br J Dermatol. 2013;168(2):412-421.
    • (2013) Br J Dermatol , vol.168 , Issue.2 , pp. 412-421
    • Papp, K.A.1    Langley, R.G.2    Sigurgeirsson, B.3
  • 49
    • 84907871730 scopus 로고    scopus 로고
    • Secukinumab improves the signs and symptoms of moderate-to-severe plaque psoriasis in subjects with involvement of hands and/or feet: Subanalysis of a randomized, double-blind, placebo-controlled, phase 2 dose-ranging study
    • Epub December 13
    • Sigurgeirsson B, Kircik L, Nemoto O, et al. Secukinumab improves the signs and symptoms of moderate-to-severe plaque psoriasis in subjects with involvement of hands and/or feet: subanalysis of a randomized, double-blind, placebo-controlled, phase 2 dose-ranging study. J Eur Acad Dermatol Venereol. Epub December 13, 2013.
    • (2013) J Eur Acad Dermatol Venereol
    • Sigurgeirsson, B.1    Kircik, L.2    Nemoto, O.3
  • 50
    • 84873168729 scopus 로고    scopus 로고
    • Secukinumab induction and maintenance therapy in moderate-to-severe plaque psoriasis: A randomized, double-blind, placebo-controlled, phase II regimen-finding study
    • Rich P, Sigurgeirsson B, Thaci D, et al. Secukinumab induction and maintenance therapy in moderate-to-severe plaque psoriasis: a randomized, double-blind, placebo-controlled, phase II regimen-finding study. Br J Dermatol. 2012;168(2):402-411.
    • (2012) Br J Dermatol , vol.168 , Issue.2 , pp. 402-411
    • Rich, P.1    Sigurgeirsson, B.2    Thaci, D.3
  • 51
    • 84912024938 scopus 로고    scopus 로고
    • Secukinumab improves hand, foot and nail lesions in moderate-to-severe plaque psoriasis: Subanalysis of a randomized, double-blind, placebo-controlled, regimen-finding phase 2 trial
    • The CAIN457A2211 study group, Epub January 7
    • Paul C, Reich K, Gottlieb AB, et al; The CAIN457A2211 study group. Secukinumab improves hand, foot and nail lesions in moderate-to-severe plaque psoriasis: subanalysis of a randomized, double-blind, placebo-controlled, regimen-finding phase 2 trial. J Eur Acad Dermatol Venereol. Epub January 7, 2014.
    • (2014) J Eur Acad Dermatol Venereol
    • Paul, C.1    Reich, K.2    Gottlieb, A.B.3
  • 53
    • 84907879638 scopus 로고    scopus 로고
    • Secukinumab efficacy in subjects with moderate to severe plaque psoriasis: Pooled subgroup analyses by patient age of 4 phase 3 clinical studies
    • Warren R, Guettner A, Morita A, Gisondi P, Cooper S. Secukinumab efficacy in subjects with moderate to severe plaque psoriasis: Pooled subgroup analyses by patient age of 4 phase 3 clinical studies. J Am Acad Dermatol. 2014;70(5 Supplement 1):AB186.
    • (2014) J Am Acad Dermatol , vol.70 , pp. AB186
    • Warren, R.1    Guettner, A.2    Morita, A.3    Gisondi, P.4    Cooper, S.5
  • 54
    • 84907864706 scopus 로고    scopus 로고
    • Secukinumab versus placebo or etanercept on time to response on patient-reported psoriasis symptoms of pain, itching, and scaling (FIXTURE study)
    • Elewski B, McLeod L, Lebwohl M, Mallya UG, Zhao Y. Secukinumab versus placebo or etanercept on time to response on patient-reported psoriasis symptoms of pain, itching, and scaling (FIXTURE study). J Am Acad Dermatol. 2014;70(5 Supplement 1):AB189.
    • (2014) J Am Acad Dermatol , vol.70 , pp. AB189
    • Elewski, B.1    McLeod, L.2    Lebwohl, M.3    Mallya, U.G.4    Zhao, Y.5
  • 55
    • 84862860846 scopus 로고    scopus 로고
    • IL-17A is essential for cell activation and inflammatory gene circuits in subjects with psoriasis
    • Krueger JG, Fretzin S, Suárez-Fariñas M, et al. IL-17A is essential for cell activation and inflammatory gene circuits in subjects with psoriasis. J Allergy Clin Immunol. 2012;130(1):145-154.
    • (2012) J Allergy Clin Immunol , vol.130 , Issue.1 , pp. 145-154
    • Krueger, J.G.1    Fretzin, S.2    Suárez-Fariñas, M.3
  • 56
    • 84859073115 scopus 로고    scopus 로고
    • Anti-interleukin-17 monoclonal antibody ixekizumab in chronic plaque psoriasis
    • Leonardi C, Matheson R, Zachariae C, et al. Anti-interleukin-17 monoclonal antibody ixekizumab in chronic plaque psoriasis. N Engl J Med. 2012;366(13):1190-1199.
    • (2012) N Engl J Med , vol.366 , Issue.13 , pp. 1190-1199
    • Leonardi, C.1    Matheson, R.2    Zachariae, C.3
  • 57
    • 84887968942 scopus 로고    scopus 로고
    • Early clinical response as a predictor of subsequent response to ixekizumab treatment: Results from a phase II study of patients with moderate-to-severe plaque psoriasis
    • Zhu B, Edson-Heredia E, Cameron GS, et al. Early clinical response as a predictor of subsequent response to ixekizumab treatment: results from a phase II study of patients with moderate-to-severe plaque psoriasis. Br J Dermatol. 2013;169(6):1337-1341.
    • (2013) Br J Dermatol , vol.169 , Issue.6 , pp. 1337-1341
    • Zhu, B.1    Edson-Heredia, E.2    Cameron, G.S.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.