Insulin inhibits AMPK activity and phosphorylates AMPK Ser485/491 through Akt in hepatocytes, myotubes and incubated rat skeletal muscle

Archives of Biochemistry and Biophysics

Volumn 562, Issue , 2014, Pages 62-69

  Valentine, Rudy J ^a   Coughlan, Kimberly A ^a   Ruderman, Neil B ^a   Saha, Asish K ^a  

^a BOSTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

AMPK; Growth factors; Insulin; PKB; Ser485 491

Indexed keywords

HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; INSULIN; MAMMALIAN TARGET OF RAPAMYCIN; PROTEIN KINASE B; RAPAMYCIN; SERINE; AMP-ACTIVATED PROTEIN KINASE ALPHA1 PROTEIN, RAT; AMPK ALPHA1 SUBUNIT, MOUSE; AMPK ALPHA2 SUBUNIT, MOUSE; PRKAA1 PROTEIN, HUMAN; PRKAA2 PROTEIN, HUMAN; PRKAA2 PROTEIN, RAT; SOMATOMEDIN C;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; INSULIN TREATMENT; LIVER CELL; MALE; NONHUMAN; RAT; SKELETAL MUSCLE; ANIMAL; CELL LINE; DRUG EFFECTS; GENETICS; HEPG2 CELL LINE; HUMAN; METABOLISM; MOUSE; PHOSPHORYLATION; SPRAGUE DAWLEY RAT;

AMP-ACTIVATED PROTEIN KINASES; ANIMALS; CELL LINE; HEP G2 CELLS; HEPATOCYTES; HUMANS; INSULIN; INSULIN-LIKE GROWTH FACTOR I; MALE; MICE; MUSCLE FIBERS, SKELETAL; MUSCLE, SKELETAL; PHOSPHORYLATION; RATS; RATS, SPRAGUE-DAWLEY; SERINE; SIROLIMUS;

EID: 84907809393     PISSN: 00039861     EISSN: 10960384     Source Type: Journal    
DOI: 10.1016/j.abb.2014.08.013     Document Type: Article

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