Posttraumatic administration of luteolin protects mice from traumatic brain injury: Implication of autophagy and inflammation

Brain Research

Volumn 1582, Issue , 2014, Pages 237-246

  Xu, Jianguo ^a   Wang, Handong ^a   Lu, Xinyu ^a   Ding, Ke ^a   Zhang, Li ^a   He, Jin ^a   Wei, Wuting ^b   Wu, Yong ^a  

^a NANJING UNIVERSITY   (China)

^b SOUTHERN MEDICAL UNIVERSITY   (China)

Author keywords

Autophagy; Inflammation; Luteolin; Neuroprotection; Traumatic brain injury

Indexed keywords

INTERLEUKIN 1BETA; LUTEOLIN; MESSENGER RNA; SYNAPTOTAGMIN I; TUMOR NECROSIS FACTOR ALPHA; IL1B PROTEIN, MOUSE; NEUROPROTECTIVE AGENT;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTOPHAGY; BLOOD BRAIN BARRIER; BRAIN EDEMA; CONTROLLED STUDY; IMMUNOFLUORESCENCE; INFLAMMATION; MALE; MOUSE; NERVE CELL DEGENERATION; NEUROPROTECTION; NONHUMAN; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; TRAUMATIC BRAIN INJURY; WESTERN BLOTTING; ANIMAL; BRAIN; BRAIN INJURIES; CAPILLARY PERMEABILITY; DISEASE MODEL; DRUG EFFECTS; FLUORESCENT ANTIBODY TECHNIQUE; IMMUNOLOGY; IMMUNOMODULATION; METABOLISM; NERVE CELL; PATHOLOGY; PATHOPHYSIOLOGY; PHYSIOLOGY; RANDOMIZATION;

MUS;

ANIMALS; AUTOPHAGY; BLOOD-BRAIN BARRIER; BLOTTING, WESTERN; BRAIN; BRAIN EDEMA; BRAIN INJURIES; CAPILLARY PERMEABILITY; DISEASE MODELS, ANIMAL; FLUORESCENT ANTIBODY TECHNIQUE; INTERLEUKIN-1BETA; LUTEOLIN; MALE; MICE; NEUROIMMUNOMODULATION; NEURONS; NEUROPROTECTIVE AGENTS; RANDOM ALLOCATION; REAL-TIME POLYMERASE CHAIN REACTION; RNA, MESSENGER; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84907779422     PISSN: 00068993     EISSN: 18726240     Source Type: Journal    
DOI: 10.1016/j.brainres.2014.07.042     Document Type: Article

References (39)

1. J.C. Brooks, D.J. Strauss, R.M. Shavelle, D.R. Paculdo, F.M. Hammond, and C.L. Harrison-Felix Long-term disability and survival in traumatic brain injury: results from the National Institute on Disability and Rehabilitation Research Model Systems Arch. Phys. Med. Rehabil. 94 2013 2203 2209
2. D. Cederberg, and P. Siesjo What has inflammation to do with traumatic brain injury? Childs Nerv. Syst. 26 2010 221 226
3. F. Clausen, A. Hanell, C. Israelsson, J. Hedin, T. Ebendal, A.K. Mir, H. Gram, and N. Marklund Neutralization of interleukin-1beta reduces cerebral edema and tissue loss and improves late cognitive outcome following traumatic brain injury in mice Eur. J. Neurosci. 34 2011 110 123
4. F. Dajas, A.C. Andres, A. Florencia, E. Carolina, and R.M. Felicia Neuroprotective actions of flavones and flavonols: mechanisms and relationship to flavonoid structural features Cent. Nerv. Syst. Agents Med. Chem. 13 2013 30 35
5. S. Erlich, A. Alexandrovich, E. Shohami, and R. Pinkas-Kramarski Rapamycin is a neuroprotective treatment for traumatic brain injury Neurobiol. Dis. 26 2007 86 93
6. M.A. Flierl, P.F. Stahel, K.M. Beauchamp, S.J. Morgan, W.R. Smith, and E. Shohami Mouse closed head injury model induced by a weight-drop device Nat. Protoc. 4 2009 1328 1337
7. Y. Fujishima, S. Nishiumi, A. Masuda, J. Inoue, N.M. Nguyen, Y. Irino, M. Komatsu, K. Tanaka, H. Kutsumi, T. Azuma, and M. Yoshida Autophagy in the intestinal epithelium reduces endotoxin-induced inflammatory responses by inhibiting NF-kappaB activation Arch. Biochem. Biophys. 506 2011 223 235
8. S. Ghavami, S. Shojaei, B. Yeganeh, S.R. Ande, J.R. Jangamreddy, M. Mehrpour, J. Christoffersson, W. Chaabane, A.R. Moghadam, H.H. Kashani, M. Hashemi, A.A. Owji, and M.J. Los Autophagy and apoptosis dysfunction in neurodegenerative disorders Prog. Neurobiol. 112 2014 24 49
9. H.C. Huang, K.Y. Syu, and J.K. Lin Chemical composition of Solanum nigrum linn extract and induction of autophagy by leaf water extract and its major flavonoids in AU565 breast cancer cells J. Agric. Food Chem. 58 2010 8699 8708
10. J. Kim, T.Y. Kim, K.S. Cho, H.N. Kim, and J.Y. Koh Autophagy activation and neuroprotection by progesterone in the G93A-SOD1 transgenic mouse model of amyotrophic lateral sclerosis Neurobiol. Dis. 59 2013 80 85
11. A. Kumar, and D.J. Loane Neuroinflammation after traumatic brain injury: opportunities for therapeutic intervention Brain Behav. Immun. 26 2012 1191 1201
12. L. Li, J. Hai, Z. Li, Y. Zhang, H. Peng, K. Li, and X. Weng Resveratrol modulates autophagy and NF-kappaB activity in a murine model for treating non-alcoholic fatty liver disease Food Chem. Toxicol. 63 2014 166 173
13. X. Lin, S. Li, Y. Zhao, X. Ma, K. Zhang, X. He, and Z. Wang Interaction domains of p62: a bridge between p62 and selective autophagy DNA Cell Biol. 32 2013 220 227
14. C.L. Luo, B.X. Li, Q.Q. Li, X.P. Chen, Y.X. Sun, H.J. Bao, D.K. Dai, Y.W. Shen, H.F. Xu, H. Ni, L. Wan, Z.H. Qin, L.Y. Tao, and Z.Q. Zhao Autophagy is involved in traumatic brain injury-induced cell death and contributes to functional outcome deficits in mice Neuroscience 184 2011 54 63
15. L. Lv, L. Lv, Y. Zhang, and Q. Kong Luteolin prevents LPS-induced TNF-alpha expression in cardiac myocytes through inhibiting NF-kappaB signaling pathway Inflammation 34 2011 620 629
16. K.W. McConeghy, J. Hatton, L. Hughes, and A.M. Cook A review of neuroprotection pharmacology and therapies in patients with acute traumatic brain injury CNS Drugs 26 2012 613 636
17. C. Miracco, E. Cosci, G. Oliveri, P. Luzi, L. Pacenti, I. Monciatti, S. Mannucci, M.C. De Nisi, M. Toscano, V. Malagnino, S.M. Falzarano, L. Pirtoli, and P. Tosi Protein and mRNA expression of autophagy gene Beclin 1 in human brain tumours Int. J. Oncol. 30 2007 429 436
18. L. Murrow, and J. Debnath Autophagy as a stress-response and quality-control mechanism: implications for cell injury and human disease Annu. Rev. Pathol. 8 2013 105 137
19. C.M. Park, K.S. Jin, Y.W. Lee, and Y.S. Song Luteolin and chicoric acid synergistically inhibited inflammatory responses via inactivation of PI3K-Akt pathway and impairment of NF-kappaB translocation in LPS stimulated RAW 264.7 cells Eur. J. Pharmacol. 660 2011 454 459
20. C.M. Park, and Y.S. Song Luteolin and luteolin-7-O-glucoside inhibit lipopolysaccharide-induced inflammatory responses through modulation of NF-kappaB/AP-1/PI3K-Akt signaling cascades in RAW 264.7 cells Nutr. Res. Pract. 7 2013 423 429
21. S.H. Park, H.S. Park, J.H. Lee, G.Y. Chi, G.Y. Kim, S.K. Moon, Y.C. Chang, J.W. Hyun, W.J. Kim, and Y.H. Choi Induction of endoplasmic reticulum stress-mediated apoptosis and non-canonical autophagy by luteolin in NCI-H460 lung carcinoma cells Food Chem. Toxicol. 56 2013 100 109
22. H. Qiao, L. Dong, X. Zhang, C. Zhu, X. Zhang, L. Wang, Z. Liu, L. Chen, Y. Xing, C. Wang, and Y. Li Protective effect of luteolin in experimental ischemic stroke: upregulated SOD1, CAT, Bcl-2 and claudin-5, down-regulated MDA and Bax expression Neurochem. Res. 37 2012 2014 2024
23. H. Qiao, X. Zhang, C. Zhu, L. Dong, L. Wang, X. Zhang, Y. Xing, C. Wang, Y. Ji, and X. Cao Luteolin downregulates TLR4, TLR5, NF-kappaB and p-p38MAPK expression, upregulates the p-ERK expression, and protects rat brains against focal ischemia Brain Res. 1448 2012 71 81
24. D.F. Romagnolo, and O.I. Selmin Flavonoids and cancer prevention: a review of the evidence J Nutr Gerontol Geriatr 31 2012 206 238
25. D.C. Rubinsztein, G. Marino, and G. Kroemer Autophagy and aging Cell 146 2011 682 695
26. D.C. Rubinsztein, P. Codogno, and B. Levine Autophagy modulation as a potential therapeutic target for diverse diseases Nat. Rev. Drug Discov. 11 2012 709 730
27. S.W. Ryter, S.M. Cloonan, and A.M. Choi Autophagy: a critical regulator of cellular metabolism and homeostasis Mol. Cells. 36 2013 7 16
28. D. Sawmiller, S. Li, M. Shahaduzzaman, A.J. Smith, D. Obregon, B. Giunta, C.V. Borlongan, P.R. Sanberg, and J. Tan Luteolin reduces Alzheimers disease pathologies induced by traumatic brain injury Int. J. Mol. Sci. 15 2014 895 904
29. V. Sharma, M. Mishra, S. Ghosh, R. Tewari, A. Basu, P. Seth, and E. Sen Modulation of interleukin-1beta mediated inflammatory response in human astrocytes by flavonoids: implications in neuroprotection Brain Res. Bull. 73 2007 55 63
30. C.C. Tan, J.T. Yu, M.S. Tan, T. Jiang, X.C. Zhu, and L. Tan Autophagy in aging and neurodegenerative diseases: implications for pathogenesis and therapy Neurobiol. Aging 35 2014 941 957
31. O. Uyama, N. Okamura, M. Yanase, M. Narita, K. Kawabata, and M. Sugita Quantitative evaluation of vascular permeability in the gerbil brain after transient ischemia using Evans blue fluorescence J. Cereb. Blood Flow Metab. 8 1988 282 284
32. G.G. Vecil, P.H. Larsen, S.M. Corley, L.M. Herx, A. Besson, C.G. Goodyer, and V.W. Yong Interleukin-1 is a key regulator of matrix metalloproteinase-9 expression in human neurons in culture and following mouse brain trauma in vivo J. Neurosci. Res. 61 2000 212 224
33. M.T. Viscomi, M. DAmelio, V. Cavallucci, L. Latini, E. Bisicchia, F. Nazio, F. Fanelli, M. Maccarrone, S. Moreno, F. Cecconi, and M. Molinari Stimulation of autophagy by rapamycin protects neurons from remote degeneration after acute focal brain damage Autophagy 8 2012 222 235
34. J. Wang, J. Fields, C. Zhao, J. Langer, R.K. Thimmulappa, T.W. Kensler, M. Yamamoto, S. Biswal, and S. Dore Role of Nrf2 in protection against intracerebral hemorrhage injury in mice Free Radic. Biol. Med. 43 2007 408 414
35. J. Xu, H. Wang, K. Ding, X. Lu, T. Li, J. Wang, C. Wang, and J. Wang Inhibition of cathepsin s produces neuroprotective effects after traumatic brain injury in mice Mediat. Inflamm. 2013 2013 187873
36. J. Xu, H. Wang, K. Ding, L. Zhang, C. Wang, T. Li, W. Wei, and X. Lu Luteolin provides neuroprotection in models of traumatic brain injury via the Nrf2-ARE pathway Free Radic. Biol. Med. 71C 2014 186 195
37. Y.B. Zhang, S.X. Li, X.P. Chen, L. Yang, Y.G. Zhang, R. Liu, and L.Y. Tao Autophagy is activated and might protect neurons from degeneration after traumatic brain injury Neurosci. Bull. 24 2008 143 149
38. Y.C. Zhang, F.F. Gan, S.B. Shelar, K.Y. Ng, and E.H. Chew Antioxidant and Nrf2 inducing activities of luteolin, a flavonoid constituent in Ixeris sonchifolia Hance, provide neuroprotective effects against ischemia-induced cellular injury Food Chem. Toxicol. 59 2013 272 280
39. G. Zhao, S.Y. Zang, Z.H. Jiang, Y.Y. Chen, X.H. Ji, B.F. Lu, J.H. Wu, G.W. Qin, and L.H. Guo Postischemic administration of liposome-encapsulated luteolin prevents against ischemia-reperfusion injury in a rat middle cerebral artery occlusion model J. Nutr. Biochem. 22 2011 929 936