메뉴 건너뛰기




Volumn 22, Issue 10, 2011, Pages 929-936

Postischemic administration of liposome-encapsulated luteolin prevents against ischemia-reperfusion injury in a rat middle cerebral artery occlusion model

Author keywords

Ischemia; Luteolin; Neuroprotectant; Oxidant antioxidant balance; Reactive oxygen species; Reperfusion

Indexed keywords

CATALASE; GLUTATHIONE; HYDROGEN PEROXIDE; LIPOSOME; LUTEOLIN; REACTIVE OXYGEN METABOLITE;

EID: 80053095215     PISSN: 09552863     EISSN: 18734847     Source Type: Journal    
DOI: 10.1016/j.jnutbio.2010.07.014     Document Type: Article
Times cited : (57)

References (61)
  • 1
    • 0031885478 scopus 로고    scopus 로고
    • Medical and neurological complications of ischemic stroke: experience from the RANTTAS trial. RANTTAS Investigators
    • Johnston K.C., Li J.Y., Lyden P.D., Hanson S.K., Feasby T.E., Adams R.J., et al. Medical and neurological complications of ischemic stroke: experience from the RANTTAS trial. RANTTAS Investigators. Stroke 1998, 29:447-453.
    • (1998) Stroke , vol.29 , pp. 447-453
    • Johnston, K.C.1    Li, J.Y.2    Lyden, P.D.3    Hanson, S.K.4    Feasby, T.E.5    Adams, R.J.6
  • 2
    • 65549165864 scopus 로고    scopus 로고
    • Challenges and possibilities of intravascular cell therapy in stroke
    • Hicks A., Jolkkonen J. Challenges and possibilities of intravascular cell therapy in stroke. Acta Neurobiol Exp 2009, 69:1-11.
    • (2009) Acta Neurobiol Exp , vol.69 , pp. 1-11
    • Hicks, A.1    Jolkkonen, J.2
  • 3
    • 33646711480 scopus 로고    scopus 로고
    • Protective effect of anthocyanins in middle cerebral artery occlusion and reperfusion model of cerebral ischemia in rats
    • Shin W.H., Park S.J., Kim E.J. Protective effect of anthocyanins in middle cerebral artery occlusion and reperfusion model of cerebral ischemia in rats. Life Sci 2006, 79:130-137.
    • (2006) Life Sci , vol.79 , pp. 130-137
    • Shin, W.H.1    Park, S.J.2    Kim, E.J.3
  • 4
    • 33947628060 scopus 로고    scopus 로고
    • Molecular targets in cerebral ischemia for developing novel therapeutics
    • Mehta S.L., Manhas N., Raghubir R. Molecular targets in cerebral ischemia for developing novel therapeutics. Brain Res Rev 2007, 54:34-66.
    • (2007) Brain Res Rev , vol.54 , pp. 34-66
    • Mehta, S.L.1    Manhas, N.2    Raghubir, R.3
  • 5
    • 0033751426 scopus 로고    scopus 로고
    • Molecular mechanisms of ischemic neuronal injury
    • Neumar R.W. Molecular mechanisms of ischemic neuronal injury. Ann Emerg Med 2000, 6:483-506.
    • (2000) Ann Emerg Med , vol.6 , pp. 483-506
    • Neumar, R.W.1
  • 6
    • 29844458758 scopus 로고    scopus 로고
    • Modulation of the oxidative stress and inflammatory response by PPAR-gamma agonists in the hippocampus of rats exposed to cerebral ischemia/reperfusion
    • Collino M., Aragno M., Mastrocola R., Gallicchio M., Rosa A.C., Dianzani C., et al. Modulation of the oxidative stress and inflammatory response by PPAR-gamma agonists in the hippocampus of rats exposed to cerebral ischemia/reperfusion. Eur J Pharmacol 2006, 530:70-80.
    • (2006) Eur J Pharmacol , vol.530 , pp. 70-80
    • Collino, M.1    Aragno, M.2    Mastrocola, R.3    Gallicchio, M.4    Rosa, A.C.5    Dianzani, C.6
  • 7
    • 0032575694 scopus 로고    scopus 로고
    • Stroke damaged neurons may commit cellular suicide
    • Barinaga M. Stroke damaged neurons may commit cellular suicide. Science 1998, 281:1302-1303.
    • (1998) Science , vol.281 , pp. 1302-1303
    • Barinaga, M.1
  • 8
    • 38149001645 scopus 로고    scopus 로고
    • Oxidative stress and matrix metalloproteinase-9 in acute ischemic stroke: the Biomarker Evaluation for Antioxidant Therapies in Stroke (BEAT-Stroke) study
    • Kelly P.J., Morrow J.D., Ning M., Koroshetz W., Lo E.H., Terry E., et al. Oxidative stress and matrix metalloproteinase-9 in acute ischemic stroke: the Biomarker Evaluation for Antioxidant Therapies in Stroke (BEAT-Stroke) study. Stroke 2008, 39:100-104.
    • (2008) Stroke , vol.39 , pp. 100-104
    • Kelly, P.J.1    Morrow, J.D.2    Ning, M.3    Koroshetz, W.4    Lo, E.H.5    Terry, E.6
  • 9
    • 57449090234 scopus 로고    scopus 로고
    • Estrogen inhibits Fas-mediated apoptosis in experimental stroke
    • Jia J., Guan D., Zhu W., Alkayed N.J., Wang M.M., Hua Z., et al. Estrogen inhibits Fas-mediated apoptosis in experimental stroke. Exp Neurol 2009, 215:48-52.
    • (2009) Exp Neurol , vol.215 , pp. 48-52
    • Jia, J.1    Guan, D.2    Zhu, W.3    Alkayed, N.J.4    Wang, M.M.5    Hua, Z.6
  • 10
    • 65949103839 scopus 로고    scopus 로고
    • Prevention of ischemic brain injury by treatment with the membrane penetrating apoptosis inhibitor, TAT-BH4
    • Donnini S., Solito R., Monti M., Balduini W., Carloni S., Cimino M., et al. Prevention of ischemic brain injury by treatment with the membrane penetrating apoptosis inhibitor, TAT-BH4. Cell Cycle 2009, 8:1271-1278.
    • (2009) Cell Cycle , vol.8 , pp. 1271-1278
    • Donnini, S.1    Solito, R.2    Monti, M.3    Balduini, W.4    Carloni, S.5    Cimino, M.6
  • 12
    • 33745815173 scopus 로고    scopus 로고
    • Multipotent antioxidants: from screening to design
    • Zhang H.Y., Yang D.P., Tang G.Y. Multipotent antioxidants: from screening to design. Drug Discov Today 2006, 11:749-754.
    • (2006) Drug Discov Today , vol.11 , pp. 749-754
    • Zhang, H.Y.1    Yang, D.P.2    Tang, G.Y.3
  • 14
    • 58949100159 scopus 로고    scopus 로고
    • Antioxidant activities of polyphenols extracted from Perilla frutescens varieties
    • Meng L., Lozano Y.F., Gaydou E.M., Li B. Antioxidant activities of polyphenols extracted from Perilla frutescens varieties. Molecules 2008, 14:133-140.
    • (2008) Molecules , vol.14 , pp. 133-140
    • Meng, L.1    Lozano, Y.F.2    Gaydou, E.M.3    Li, B.4
  • 15
    • 73449092141 scopus 로고    scopus 로고
    • Functional activation of monoamine transporters by luteolin and apigenin isolated from the fruit of Perilla frutescens (L.) Britt
    • Zhao G., Qin G.W., Wang J., Chu W.J., Guo L.H. Functional activation of monoamine transporters by luteolin and apigenin isolated from the fruit of Perilla frutescens (L.) Britt. Neurochem Int 2010, 56:168-176.
    • (2010) Neurochem Int , vol.56 , pp. 168-176
    • Zhao, G.1    Qin, G.W.2    Wang, J.3    Chu, W.J.4    Guo, L.H.5
  • 16
    • 1642385070 scopus 로고    scopus 로고
    • Structural requirements for the flavonoid-mediated modulation of glutathione S-transferase P1-1 and GS-X pump activity in MCF7 breast cancer cells
    • Van Zanden J.J., Geraets L., Wortelboer H.M., van Bladeren P.J., Rietjens I.M., Cnubben N.H. Structural requirements for the flavonoid-mediated modulation of glutathione S-transferase P1-1 and GS-X pump activity in MCF7 breast cancer cells. Biochem Pharmacol 2004, 67:1607-1617.
    • (2004) Biochem Pharmacol , vol.67 , pp. 1607-1617
    • Van Zanden, J.J.1    Geraets, L.2    Wortelboer, H.M.3    van Bladeren, P.J.4    Rietjens, I.M.5    Cnubben, N.H.6
  • 17
    • 20444484556 scopus 로고    scopus 로고
    • Oral flavonoids delay recovery from experimental autoimmune encephalomyelitis in SJL mice
    • Verbeek R., van Tol E.A., van Noort J.M. Oral flavonoids delay recovery from experimental autoimmune encephalomyelitis in SJL mice. Biochem Pharmacol 2005, 70:220-228.
    • (2005) Biochem Pharmacol , vol.70 , pp. 220-228
    • Verbeek, R.1    van Tol, E.A.2    van Noort, J.M.3
  • 18
    • 58749115376 scopus 로고    scopus 로고
    • Luteolin inhibits proliferation and affects the function of stimulated rat synovial fibroblasts
    • Hou Y., Wu J., Huang Q., Guo L. Luteolin inhibits proliferation and affects the function of stimulated rat synovial fibroblasts. Cell Biol Int 2009, 33:135-147.
    • (2009) Cell Biol Int , vol.33 , pp. 135-147
    • Hou, Y.1    Wu, J.2    Huang, Q.3    Guo, L.4
  • 19
    • 33750567782 scopus 로고    scopus 로고
    • Immunomodulating effects of flavonoids on acute and chronic inflammatory responses caused by tumor necrosis factor alpha
    • Kumazawa Y., Kawaguchi K., Takimoto H. Immunomodulating effects of flavonoids on acute and chronic inflammatory responses caused by tumor necrosis factor alpha. Curr Pharm Des 2006, 12:4271-4279.
    • (2006) Curr Pharm Des , vol.12 , pp. 4271-4279
    • Kumazawa, Y.1    Kawaguchi, K.2    Takimoto, H.3
  • 20
    • 40849102404 scopus 로고    scopus 로고
    • Assessment of luteolin (3',4',5,7-tetrahydroxyflavone) neuropharmacological activity
    • Coleta M., Campos M.G., Cotrim M.D., Lima T.C., Cunha A.P. Assessment of luteolin (3',4',5,7-tetrahydroxyflavone) neuropharmacological activity. Behav Brain Res 2008, 189:75-82.
    • (2008) Behav Brain Res , vol.189 , pp. 75-82
    • Coleta, M.1    Campos, M.G.2    Cotrim, M.D.3    Lima, T.C.4    Cunha, A.P.5
  • 21
    • 33947379200 scopus 로고    scopus 로고
    • Effects of luteolin on learning acquisition in rats: involvement of the central cholinergic system
    • Tsai F.S., Peng W.H., Wang W.H., Wu C.R., Hsieh C.C., Lin Y.T., et al. Effects of luteolin on learning acquisition in rats: involvement of the central cholinergic system. Life Sci 2007, 80:1692-1698.
    • (2007) Life Sci , vol.80 , pp. 1692-1698
    • Tsai, F.S.1    Peng, W.H.2    Wang, W.H.3    Wu, C.R.4    Hsieh, C.C.5    Lin, Y.T.6
  • 22
    • 42949132323 scopus 로고    scopus 로고
    • Beta-secretase (BACE1) inhibitors from Perilla frutescens var. acuta
    • Choi S.H., Hur J.M., Yang E.J., Jun M., Park H.J., Lee K.B., et al. Beta-secretase (BACE1) inhibitors from Perilla frutescens var. acuta. Arch Pharm Res 2008, 31:183-187.
    • (2008) Arch Pharm Res , vol.31 , pp. 183-187
    • Choi, S.H.1    Hur, J.M.2    Yang, E.J.3    Jun, M.4    Park, H.J.5    Lee, K.B.6
  • 23
    • 2442530445 scopus 로고    scopus 로고
    • Flavones mitigate tumor necrosis factor-alpha-induced adhesion molecule upregulation in cultured human endothelial cells: role of nuclear factor-kB
    • Choi J.S., Choi Y.J., Park S.H., Kang J.S., Kang Y.H. Flavones mitigate tumor necrosis factor-alpha-induced adhesion molecule upregulation in cultured human endothelial cells: role of nuclear factor-kB. J Nutr 2004, 134:1013-1019.
    • (2004) J Nutr , vol.134 , pp. 1013-1019
    • Choi, J.S.1    Choi, Y.J.2    Park, S.H.3    Kang, J.S.4    Kang, Y.H.5
  • 24
    • 1042287039 scopus 로고    scopus 로고
    • Dietary compounds prevent oxidative damage and nitric oxide production by cells involved in demyelinating disease
    • van Meeteren M.E., Hendriks J.J., Dijkstra C.D., van Tol E.A. Dietary compounds prevent oxidative damage and nitric oxide production by cells involved in demyelinating disease. Biochem Pharmacol 2004, 67:967-975.
    • (2004) Biochem Pharmacol , vol.67 , pp. 967-975
    • van Meeteren, M.E.1    Hendriks, J.J.2    Dijkstra, C.D.3    van Tol, E.A.4
  • 25
    • 0024364268 scopus 로고
    • Chelating and free radical scavenging mechanisms of inhibitory action of rutin and quercetin in lipid peroxidation
    • Afanas'av I.B., Dorozhko A.I., Brodskii A.V., Kostyuk V.A., Potapovich A.I. Chelating and free radical scavenging mechanisms of inhibitory action of rutin and quercetin in lipid peroxidation. Biochem Pharmacol 1989, 38:1763-1769.
    • (1989) Biochem Pharmacol , vol.38 , pp. 1763-1769
    • Afanas'av, I.B.1    Dorozhko, A.I.2    Brodskii, A.V.3    Kostyuk, V.A.4    Potapovich, A.I.5
  • 26
    • 0033118665 scopus 로고    scopus 로고
    • The mitogen-activated protein kinase pathway mediates estrogen neuroprotection after glutamate toxicity in primary cortical neurons
    • Singer C.A., Figueroa-Masot X.A., Batchelor R.H., Dorsa D.M. The mitogen-activated protein kinase pathway mediates estrogen neuroprotection after glutamate toxicity in primary cortical neurons. J Neurosci 1999, 19:2455-2463.
    • (1999) J Neurosci , vol.19 , pp. 2455-2463
    • Singer, C.A.1    Figueroa-Masot, X.A.2    Batchelor, R.H.3    Dorsa, D.M.4
  • 29
    • 0035667431 scopus 로고    scopus 로고
    • 2+-inducedmembrane permeability transition in brain mitochondria
    • 2+-inducedmembrane permeability transition in brain mitochondria. J Neurochem 2001, 79:1237-1245.
    • (2001) J Neurochem , vol.79 , pp. 1237-1245
    • Maciel, E.N.1    Vercesi, A.E.2    Castilho, R.F.3
  • 30
    • 42749085478 scopus 로고    scopus 로고
    • Nonclassical secretion of human catalase on the surface of CHO cells is more efficient than classical secretion
    • He Z., Sun X., Mei G., Yu S., Li N. Nonclassical secretion of human catalase on the surface of CHO cells is more efficient than classical secretion. Cell Biol Int 2008, 32:367-373.
    • (2008) Cell Biol Int , vol.32 , pp. 367-373
    • He, Z.1    Sun, X.2    Mei, G.3    Yu, S.4    Li, N.5
  • 32
    • 0017184389 scopus 로고
    • A rapid and sensitive method for the quantification of microgram quantities of protein utilizing the principle of protein-dye binding
    • Bradford M.M. A rapid and sensitive method for the quantification of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 1976, 72:248-254.
    • (1976) Anal Biochem , vol.72 , pp. 248-254
    • Bradford, M.M.1
  • 33
    • 0032948625 scopus 로고    scopus 로고
    • Lipid peroxidative damage on pyrethroid exposure and alterations in antioxidant status in rat erythrocytes: a possible involvement of reactive oxygen species
    • Kale M., Rathore N., John S., Bhatnagar D. Lipid peroxidative damage on pyrethroid exposure and alterations in antioxidant status in rat erythrocytes: a possible involvement of reactive oxygen species. Toxicol Lett 1999, 105:197-205.
    • (1999) Toxicol Lett , vol.105 , pp. 197-205
    • Kale, M.1    Rathore, N.2    John, S.3    Bhatnagar, D.4
  • 34
    • 37349048899 scopus 로고    scopus 로고
    • Reduction of cerebral infarction in rats by biliverdin associated with amelioration of oxidative stress
    • Deguchi K., Hayashi T., Nagotan S., Sehara Y., Zhang H., Tsuchiya A., et al. Reduction of cerebral infarction in rats by biliverdin associated with amelioration of oxidative stress. Brain Res 2008, 1188:1-8.
    • (2008) Brain Res , vol.1188 , pp. 1-8
    • Deguchi, K.1    Hayashi, T.2    Nagotan, S.3    Sehara, Y.4    Zhang, H.5    Tsuchiya, A.6
  • 35
    • 58149279285 scopus 로고    scopus 로고
    • Resveratrol exerts its neuroprotective effect by modulating mitochondrial dysfunctions and associated cell death during cerebral ischemia
    • Yousuf S., Atif F., Ahmad M., Hoda N., Ishrat T., Khan B., et al. Resveratrol exerts its neuroprotective effect by modulating mitochondrial dysfunctions and associated cell death during cerebral ischemia. Brain Res 2009, 1250:242-253.
    • (2009) Brain Res , vol.1250 , pp. 242-253
    • Yousuf, S.1    Atif, F.2    Ahmad, M.3    Hoda, N.4    Ishrat, T.5    Khan, B.6
  • 36
    • 0036284568 scopus 로고    scopus 로고
    • Thrombolysis-related hemorrhagic infarction: a marker of early reperfusion, reduced infarct size, and improved outcome in patients with proximal middle cerebral artery occlusion
    • Molina C.A., Alvarez-Sabín J., Montaner J., Abilleira S., Arenillas J.F., Coscojuela P., et al. Thrombolysis-related hemorrhagic infarction: a marker of early reperfusion, reduced infarct size, and improved outcome in patients with proximal middle cerebral artery occlusion. Stroke 2002, 33:1551-1556.
    • (2002) Stroke , vol.33 , pp. 1551-1556
    • Molina, C.A.1    Alvarez-Sabín, J.2    Montaner, J.3    Abilleira, S.4    Arenillas, J.F.5    Coscojuela, P.6
  • 37
    • 65149094080 scopus 로고    scopus 로고
    • Integrated brain restoration after ischemic stroke - medical management, risk factors, nutrients, and other interventions for managing inflammation and enhancing brain plasticity
    • Kidd P.M. Integrated brain restoration after ischemic stroke - medical management, risk factors, nutrients, and other interventions for managing inflammation and enhancing brain plasticity. Altern Med Rev 2009, 14:14-35.
    • (2009) Altern Med Rev , vol.14 , pp. 14-35
    • Kidd, P.M.1
  • 39
    • 33750742747 scopus 로고    scopus 로고
    • An extended window of opportunity for G-CSF treatment in cerebral ischemia
    • Schneider A., Wysocki R., Pitzer C., Krüger C., Laage R., Schwab S., et al. An extended window of opportunity for G-CSF treatment in cerebral ischemia. BMC Biol 2006, 4:36.
    • (2006) BMC Biol , vol.4 , pp. 36
    • Schneider, A.1    Wysocki, R.2    Pitzer, C.3    Krüger, C.4    Laage, R.5    Schwab, S.6
  • 40
    • 60549106649 scopus 로고    scopus 로고
    • Protective effect of delayed treatment with low-dose glibenclamide in three models of ischemic stroke
    • Simard J.M., Yurovsky V., Tsymbalyuk N., Melnichenko L., Ivanova S., Gerzanich V. Protective effect of delayed treatment with low-dose glibenclamide in three models of ischemic stroke. Stroke 2009, 40:604-609.
    • (2009) Stroke , vol.40 , pp. 604-609
    • Simard, J.M.1    Yurovsky, V.2    Tsymbalyuk, N.3    Melnichenko, L.4    Ivanova, S.5    Gerzanich, V.6
  • 42
    • 0034468736 scopus 로고    scopus 로고
    • Role of reactive oxygen species (ROS) in apoptosis induction
    • Simon H.U., Haj-Yehia A., Levi-Schaffer F. Role of reactive oxygen species (ROS) in apoptosis induction. Apoptosis 2000, 5:415-418.
    • (2000) Apoptosis , vol.5 , pp. 415-418
    • Simon, H.U.1    Haj-Yehia, A.2    Levi-Schaffer, F.3
  • 43
    • 33646675336 scopus 로고    scopus 로고
    • Redox modulation of heat shock protein expression by acetylcarnitine in aging brain: relationship to antioxidant status and mitochondrial function
    • Calabrese V., Colombrita C., Sultana R., Scapagnini G., Calvani M., Butterfield D.A., et al. Redox modulation of heat shock protein expression by acetylcarnitine in aging brain: relationship to antioxidant status and mitochondrial function. Antioxid Redox Signal 2006, 8:404-416.
    • (2006) Antioxid Redox Signal , vol.8 , pp. 404-416
    • Calabrese, V.1    Colombrita, C.2    Sultana, R.3    Scapagnini, G.4    Calvani, M.5    Butterfield, D.A.6
  • 44
    • 0034304391 scopus 로고    scopus 로고
    • NO synthase and NO-dependent signal pathways in brain aging and neurodegenerative disorders: the role of oxidant/antioxidant balance
    • Calabrese V., Bates T.E., Stella A.M. NO synthase and NO-dependent signal pathways in brain aging and neurodegenerative disorders: the role of oxidant/antioxidant balance. Neurochem Res 2000, 25:1315-1341.
    • (2000) Neurochem Res , vol.25 , pp. 1315-1341
    • Calabrese, V.1    Bates, T.E.2    Stella, A.M.3
  • 46
    • 80053108603 scopus 로고    scopus 로고
    • NMDA receptor blockage with 2-amino-5-phosphonovaleric acid improves oxidative stress after spinal cord trauma in rats
    • Vural M., Arslantaş A., Yazihan N., Köken T., Uzuner K., Arslantaş D., et al. NMDA receptor blockage with 2-amino-5-phosphonovaleric acid improves oxidative stress after spinal cord trauma in rats. Spinal Cord 2009, 100. 10.1038/sc.
    • (2009) Spinal Cord , pp. 100
    • Vural, M.1    Arslantaş, A.2    Yazihan, N.3    Köken, T.4    Uzuner, K.5    Arslantaş, D.6
  • 47
    • 0347318119 scopus 로고    scopus 로고
    • New perspectives on vitamin E: gamma-tocopherol and carboxyelthylhydroxychroman metabolites in biology and medicine
    • Hensley K., Benaksas E.J., Bolli R., Comp P., Grammas P., Hamdheydari L., et al. New perspectives on vitamin E: gamma-tocopherol and carboxyelthylhydroxychroman metabolites in biology and medicine. Free Radic Biol Med 2004, 36:1-15.
    • (2004) Free Radic Biol Med , vol.36 , pp. 1-15
    • Hensley, K.1    Benaksas, E.J.2    Bolli, R.3    Comp, P.4    Grammas, P.5    Hamdheydari, L.6
  • 48
    • 0036399717 scopus 로고    scopus 로고
    • Combination therapy for ischemic stroke: potential of neuroprotectants plus thrombolytics
    • Chen S.D., Lee J.M., Yang D.I., Nassief A., Hsu C.Y. Combination therapy for ischemic stroke: potential of neuroprotectants plus thrombolytics. Am J Cardiovasc Drugs 2002, 2:303-313.
    • (2002) Am J Cardiovasc Drugs , vol.2 , pp. 303-313
    • Chen, S.D.1    Lee, J.M.2    Yang, D.I.3    Nassief, A.4    Hsu, C.Y.5
  • 49
    • 0034648748 scopus 로고    scopus 로고
    • Accumulation of 4-hydroxynonenal-modified proteins in hippocampal CA1 pyramidal neurons precedes delayed neuronal damage in the gerbil brain
    • Urabe T., Yamasaki Y., Hattori N., Yoshikawa M., Uchida K., Mizuno Y. Accumulation of 4-hydroxynonenal-modified proteins in hippocampal CA1 pyramidal neurons precedes delayed neuronal damage in the gerbil brain. Neuroscience 2000, 100:241-250.
    • (2000) Neuroscience , vol.100 , pp. 241-250
    • Urabe, T.1    Yamasaki, Y.2    Hattori, N.3    Yoshikawa, M.4    Uchida, K.5    Mizuno, Y.6
  • 50
    • 5444243895 scopus 로고    scopus 로고
    • Extracranial thrombotically active carotid plaque as a risk factor for ischemic stroke
    • Spagnoli L.G., Mauriello A., Sangiorgi G., Fratoni S., Bonanno E., Schwartz R.S., et al. Extracranial thrombotically active carotid plaque as a risk factor for ischemic stroke. JAMA 2004, 292:1845-1852.
    • (2004) JAMA , vol.292 , pp. 1845-1852
    • Spagnoli, L.G.1    Mauriello, A.2    Sangiorgi, G.3    Fratoni, S.4    Bonanno, E.5    Schwartz, R.S.6
  • 51
    • 36148988399 scopus 로고    scopus 로고
    • Luteolin suppresses inflammation-associated gene expression by blocking NF-kappaB and AP-1 activation pathway in mouse alveolar macrophages
    • Chen C.Y., Peng W.H., Tsai K.D., Hsu S.L. Luteolin suppresses inflammation-associated gene expression by blocking NF-kappaB and AP-1 activation pathway in mouse alveolar macrophages. Life Sci 2007, 81:1602-1614.
    • (2007) Life Sci , vol.81 , pp. 1602-1614
    • Chen, C.Y.1    Peng, W.H.2    Tsai, K.D.3    Hsu, S.L.4
  • 52
    • 3142709948 scopus 로고    scopus 로고
    • Bioactive compounds in nutrition and health research methodologies for establishing biological function: the antioxidant and anti-inflammatory effects of flavonoids on atherosclerosis
    • Kris-Etherton P.M., Lefevre M., Beecher G.R., Gross M.D., Keen C.L., Etherton T.D. Bioactive compounds in nutrition and health research methodologies for establishing biological function: the antioxidant and anti-inflammatory effects of flavonoids on atherosclerosis. Annu Rev Nutr 2004, 24:511-538.
    • (2004) Annu Rev Nutr , vol.24 , pp. 511-538
    • Kris-Etherton, P.M.1    Lefevre, M.2    Beecher, G.R.3    Gross, M.D.4    Keen, C.L.5    Etherton, T.D.6
  • 53
    • 70449707436 scopus 로고    scopus 로고
    • Luteolin as a therapeutic option for multiple sclerosis
    • Theoharides T.C. Luteolin as a therapeutic option for multiple sclerosis. J Neuroinflammation 2009, 6:29.
    • (2009) J Neuroinflammation , vol.6 , pp. 29
    • Theoharides, T.C.1
  • 54
    • 68049102040 scopus 로고    scopus 로고
    • The anti-amnesic effects of luteolin against amyloid β25-35 peptide-induced toxicity in mice involve the protection of neurovascular unit
    • Liu R., Gao M., Qiang G.F., Zhang T.T., Lan X., Ying J., et al. The anti-amnesic effects of luteolin against amyloid β25-35 peptide-induced toxicity in mice involve the protection of neurovascular unit. Neuroscience 2009, 162:1232-1243.
    • (2009) Neuroscience , vol.162 , pp. 1232-1243
    • Liu, R.1    Gao, M.2    Qiang, G.F.3    Zhang, T.T.4    Lan, X.5    Ying, J.6
  • 55
    • 55449137936 scopus 로고    scopus 로고
    • Mediterranean diet and cardioprotection: wild artichoke inhibits metalloproteinase 9
    • Bellosta S., Bogani P., Canavesi M., Galli C., Visioli F. Mediterranean diet and cardioprotection: wild artichoke inhibits metalloproteinase 9. Mol Nutr Food Res 2008, 52:1147-1152.
    • (2008) Mol Nutr Food Res , vol.52 , pp. 1147-1152
    • Bellosta, S.1    Bogani, P.2    Canavesi, M.3    Galli, C.4    Visioli, F.5
  • 56
    • 38149001645 scopus 로고    scopus 로고
    • Oxidative stress and matrix metalloproteinase-9 in acute ischemic stroke: the Biomarker Evaluation for Antioxidant Therapies in Stroke (BEAT-Stroke) study
    • Lee H., Stevenson E., Lederer M., Furie K.L. Oxidative stress and matrix metalloproteinase-9 in acute ischemic stroke: the Biomarker Evaluation for Antioxidant Therapies in Stroke (BEAT-Stroke) study. Stroke 2008, 39:100-104.
    • (2008) Stroke , vol.39 , pp. 100-104
    • Lee, H.1    Stevenson, E.2    Lederer, M.3    Furie, K.L.4
  • 57
    • 4243063942 scopus 로고    scopus 로고
    • Flavonoids from artichoke (Cynara scolymus L.) up-regulate endothelial-type nitric-oxide synthase gene expression in human endothelial cells
    • Li H., Xia N., Brausch I., Yao Y., Förstermann U. Flavonoids from artichoke (Cynara scolymus L.) up-regulate endothelial-type nitric-oxide synthase gene expression in human endothelial cells. J Pharmacol Exp Ther 2004, 310:926-932.
    • (2004) J Pharmacol Exp Ther , vol.310 , pp. 926-932
    • Li, H.1    Xia, N.2    Brausch, I.3    Yao, Y.4    Förstermann, U.5
  • 58
    • 34447311424 scopus 로고    scopus 로고
    • Flavonoids inhibit the platelet TxA(2) signalling pathway and antagonize TxA(2) receptors (TP) in platelets and smooth muscle cells
    • Guerrero J.A., Navarro-Nuñez L., Lozano M.L., Martínez C., Vicente V., Gibbins J.M., et al. Flavonoids inhibit the platelet TxA(2) signalling pathway and antagonize TxA(2) receptors (TP) in platelets and smooth muscle cells. Br J Clin Pharmacol 2007, 64:133-144.
    • (2007) Br J Clin Pharmacol , vol.64 , pp. 133-144
    • Guerrero, J.A.1    Navarro-Nuñez, L.2    Lozano, M.L.3    Martínez, C.4    Vicente, V.5    Gibbins, J.M.6
  • 59
    • 0033637140 scopus 로고    scopus 로고
    • The effects of plant flavonoids on mammalian cells: implications for inflammation, heart disease, and cancer
    • Middleton E., Kandaswami C., Theoharides T.C. The effects of plant flavonoids on mammalian cells: implications for inflammation, heart disease, and cancer. Pharmacol Rev 2000, 52:673-751.
    • (2000) Pharmacol Rev , vol.52 , pp. 673-751
    • Middleton, E.1    Kandaswami, C.2    Theoharides, T.C.3
  • 60
    • 77950210766 scopus 로고    scopus 로고
    • Luteolin inhibits lysophosphatidylcholine-induced apoptosis in endothelial cells by a calcium/mithocondrion/caspases-dependent pathway
    • Song J., Liu K., Yi J., Zhu D., Liu G., Liu B. Luteolin inhibits lysophosphatidylcholine-induced apoptosis in endothelial cells by a calcium/mithocondrion/caspases-dependent pathway. Planta Med 2010, 76:433-438.
    • (2010) Planta Med , vol.76 , pp. 433-438
    • Song, J.1    Liu, K.2    Yi, J.3    Zhu, D.4    Liu, G.5    Liu, B.6
  • 61
    • 38449086141 scopus 로고    scopus 로고
    • Luteolin protects rat PC12 and C6 cells against MPP+ induced toxicity via an ERK dependent Keap1-Nrf2-ARE pathway
    • Wruck C.J., Claussen M., Fuhrmann G., Römer L., Schulz A., Pufe T., et al. Luteolin protects rat PC12 and C6 cells against MPP+ induced toxicity via an ERK dependent Keap1-Nrf2-ARE pathway. J Neural Transm Suppl 2007, 72:57-67.
    • (2007) J Neural Transm Suppl , vol.72 , pp. 57-67
    • Wruck, C.J.1    Claussen, M.2    Fuhrmann, G.3    Römer, L.4    Schulz, A.5    Pufe, T.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.